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The Pupillary Light Reflex as a Biomarker of Concussion.
Frederick Robert Carrick, Sergio F Azzolino, Melissa Hunfalvay, Guido Pagnacco, Elena Oggero, Ryan CN D'Arcy, Mahera Abdulrahman, Kiminobu Sugaya
Jan 06, 2022
The size of our pupils changes continuously in response to variations in ambient light levels, a process known as the pupillary light reflex (PLR). The PLR is not a simple reflex as its function is modulated by cognitive brain...
The Pupillary Light Reflex as a Biomarker of Concussion.
Frederick Robert Carrick, Sergio F Azzolino, Melissa Hunfalvay, Guido Pagnacco, Elena Oggero, Ryan CN D'Arcy, Mahera Abdulrahman, Kiminobu Sugaya
Oct 19, 2021
The size of our pupils changes continuously in response to variations in ambient light levels, a process known as the pupillary light reflex (PLR). The PLR is not a simple reflex as its function is modulated by cognitive brain...
Anti-cN-1A autoantibodies are absent in juvenile dermatomyositis
Objective: To assess anti–cytosolic 5′-nucleotidase 1A (anti–cN-1A) autoantibodies in children with juvenile dermatomyositis (DM) and healthy controls, using 3 different methods of antibody detection, as well as verification...
Anti-cN-1A autoantibodies are absent in juvenile dermatomyositis
Objective: To assess anti–cytosolic 5′-nucleotidase 1A (anti–cN-1A) autoantibodies in children with juvenile dermatomyositis (DM) and healthy controls, using 3 different methods of antibody detection, as well as verification...
Brain Vital Signs in Elite Ice Hockey
Frederick R Carrick, Guido Pagnacco, Sergio F Azzolino, Melissa Hunfalvay, Elena Oggero, Tory Frizzell, Christopher J Smith, Gabriela Pawlowski, Natasha KJ Campbell, Shaun D Fickling, Bimal Lakhani, Ryan CN D'Arcy
Sep 26, 2021
Background: Prior concussion studies have shown that objective neurophysiological measures are sensitive to detecting concussive and subconcussive impairments in youth ice-hockey. These studies monitored brain vital signs at...
The Grizzly, February 7, 1995
Marc Ellman, Mark Leiser, Jayson Blocksidge, Michelle Ryan, Phil Caiazzo, Amy K. Davenport, Tarik Qasim, Nicole D'orsaneo, Michael A. Pizzi, Doug Plitt, Fred Klee, Joel Schofer, Ellen Cosgrove, Charlie Weingroff
Jan 01, 0001
Faculty and Administrators Focus on Sophomore Concerns Survey of Ursinus Freshmen Voice of Ursinus Rings Clear Border Dispute Between Ecuador and Peru Tabby Buckingham Dies at 16 Ursinus Students Attend March for Life ...
Ursinus College Collegeville Pennsylvania newspaper gymnastics Basketball Swimming Bridget Cauley Ellen Cosgrove campus security WVOU radio station Abortion Tabby Buckingham Michelle Ryan CIRP Sophomore Week cultural history Higher Education Liberal Studies Social History United States History
Published by: Ursinus College
Constraining cold accretion onto supermassive black holes
Tom Rose, A. C. Edge, F. Combes, M. Gaspari, S. Hamer, N. Nesvadba, A. B. Peck, C. Sarazin, G. R. Tremblay, S. A. Baum, M. N. Bremer, B. R. McNamara, C. O'Dea, J. B. R. Oonk, H. Russell, P. Salomé, M. Donahue, A. C. Fabian, G. Ferland, R. Mittal, A. Vantyghem
Oct 31, 2019
To advance our understanding of the fuelling and feedback processes which power the Universe's most massive black holes, we require a significant increase in our knowledge of the molecular gas which exists in their immediate...
Constraining cold accretion onto supermassive black holes
Tom Rose, A. C. Edge, F. Combes, M. Gaspari, S. Hamer, N. Nesvadba, A. B. Peck, C. Sarazin, G. R. Tremblay, S. A. Baum, M. N. Bremer, B. R. McNamara, C. O'Dea, J. B. R. Oonk, H. Russell, P. Salomé, M. Donahue, A. C. Fabian, G. Ferland, R. Mittal, A. Vantyghem
Oct 31, 2019
To advance our understanding of the fuelling and feedback processes which power the Universe's most massive black holes, we require a significant increase in our knowledge of the molecular gas which exists in their immediate...
A meta-analysis of techniques to promote motivation for health behaviour change from a self-determination theory perspective
A systematic review and meta-analysis was conducted of the techniques used to promote psychological need satisfaction and motivation within health interventions based on self-determination theory (SDT; Ryan & Deci, 2017)....
Autophagy Induction as a Therapeutic Strategy for Neurodegenerative Diseases.
Alvin Djajadikerta, Swati Keshri, Mariana Pavel, Ryan Prestil, Laura Ryan, David C Rubinsztein
Dec 11, 2019
Autophagy is a major, conserved cellular pathway by which cells deliver cytoplasmic contents to lysosomes for degradation. Genetic studies have revealed extensive links between autophagy and neurodegenerative disease, and...
Spinal muscular atrophy diagnosis and carrier screening from genome sequencing data.
Xiao Chen, Alba Sanchis-Juan, Courtney E French, Andrew J Connell, Isabelle Delon, Zoya Kingsbury, Aditi Chawla, Aaron L Halpern, Ryan J Taft, NIHR BioResource, David R Bentley, Matthew ER Butchbach, F Lucy Raymond, Michael A Eberle
Feb 17, 2021
PURPOSE: Spinal muscular atrophy (SMA), caused by loss of the SMN1 gene, is a leading cause of early childhood death. Due to the near identical sequences of SMN1 and SMN2, analysis of this region is challenging. Population-wide...
DIA label-free proteomic analysis of murine bone-marrow-derived macrophages.
Christa P Baker, Iain R Phair, Alejandro J Brenes, Abdelmadjid Atrih, Dylan G Ryan, Roland Bruderer, Albena T Dinkova-Kostova, Douglas J Lamont, J Simon C Arthur, Andrew JM Howden
Oct 28, 2022
Here, we describe an optimized protocol to analyze murine bone-marrow-derived macrophages using label-free data-independent acquisition (DIA) proteomics. We provide a complete step-by-step protocol describing sample preparation...
A meta-analysis of techniques to promote motivation for health behaviour change from a self-determination theory perspective
A systematic review and meta-analysis was conducted of the techniques used to promote psychological need satisfaction and motivation within health interventions based on self-determination theory (SDT; Ryan & Deci, 2017)....
Achieving robustness to aleatoric uncertainty with heteroscedastic Bayesian optimisation
Ryan-Rhys Griffiths, Alexander A Aldrick, Miguel Garcia-Ortegon, Vidhi Lalchand, Alpha A Lee
Nov 23, 2021
Abstract: Bayesian optimisation is a sample-efficient search methodology that holds great promise for accelerating drug and materials discovery programs. A frequently-overlooked modelling consideration in Bayesian optimisation...
Evidence of Next-Nearest-Neighbor Electronic Coupling in a Series of Cyano-Bridged trans-Fe(II)-Pt(IV)-M(II) (M=Fe, Ru) Asymmetric Trimers
Michael C Esposito
Jan 01, 0001
This work describes the synthesis and characterization of a series of cyano-bridged dimers and trimers of the M-Pt (M = Fe, Ru) and M-Pt-M' (M/M' = Fe, Ru) type and their electronic properties in the UV-Visible spectrum. These...
Marcus-Hush Theory Remote Electronic Coupling charge transfer Chemistry Physical Sciences and Mathematics
Published by: Ursinus College
The Utility of Arterial Spin Labeling MRI in Medial Temporal Lobe as a Vascular Biomarker in Alzheimer's Disease Spectrum
Efthymia Maria Kapasouri, Diomidis C Ioannidis, Donnie Cameron, Vassilios S Vassiliou, Michael Hornberger
Jan 25, 2023
We sought to systematically review and meta-analy the role of cerebral blood flow (CBF) in the medial temporal lobe (MTL) using arterial spin labeling magnetic resonance imaging (ASL-MRI) and compare this in patients with...
Intraoperative Monitoring of the Cochlear Nerve during Neurofibromatosis Type-2 Vestibular Schwannoma Surgery and Description of a "Test Intracochlear Electrode".
Anand V Kasbekar, Yu Chuen Tam, Robert P Carlyon, John M Deeks, Neil Donnelly, James Tysome, Richard Mannion, Patrick R Axon
Mar 15, 2019
Objectives A decision on whether to insert a cochlear implant can be made in neurofibromatosis 2 (NF2) if there is objective evidence of cochlear nerve (CN) function post vestibular schwannoma (VS) excision. We aimed to develop...
Prognostic effect of cytoreductive nephrectomy in synchronous metastatic renal cell carcinoma
Tobias Klatte, Kate Fife, Sarah J Welsh, Manavi Sachdeva, James N Armitage, Tevita 'Aho, Antony C Riddick, Athena Matakidou, Tim Eisen, Grant D Stewart
Feb 23, 2018
PURPOSE: To test the hypothesis that cytoreductive nephrectomy (CN) improves overall survival (OS) of patients with synchronous metastatic renal cell carcinoma (mRCC), who subsequently receive targeted therapies (TT). METHODS...
Nephrectomy Pazopanib Prognosis Sunitinib survival Aged Anilides Antibodies Monoclonal Antineoplastic Agents Carcinoma Renal Cell Cohort Studies Combined Modality Therapy Cytoreduction Surgical Procedures Female Humans Indazoles Indoles Kaplan-Meier Estimate Kidney Neoplasms Liver Neoplasms Lung Neoplasms Male Middle Aged Molecular Targeted Therapy Neoplasm Metastasis Nephrectomy Nivolumab Probability Prognosis Proportional Hazards Models Pyridines Pyrimidines Pyrroles Retrospective Studies Sex Factors Sulfonamides Sunitinib Survival Rate Thrombocytosis
<i>In vitro</i> conditions for performance evaluation of products for intravascular administration
Currently, there are no compendial in vitro release tests specifically indicated for parenteral formulations. Consideration of biorelevant and clinically relevant test media represents a valuable approach for the development...
Rational Design of Carbon Nitride Photoelectrodes with High Activity Toward Organic Oxidations
Carolina Pulignani, Camilo A Mesa, Sam AJ Hillman, Taylor Uekert, Sixto Giménez, James R Durrant, Erwin Reisner
Nov 15, 2022
Carbon nitride (CN x ) is a light‐absorber with excellent performance in photocatalytic suspension systems, but the activity of CN x photoelectrodes has remained low. Here, cyanamide‐functionalized CN x (NCNCN x ) was...
Construction of Bi<sub>2</sub>WO<sub>6</sub>/RGO/g-C<sub>3</sub>N<sub>4</sub> 2D/2D/2D hybrid Z-scheme heterojunctions with large interfacial contact area for efficient charge separation and high-performance photoreduction of CO<sub>2</sub> and H<sub>2</sub>O into solar fuels
We have rationally constructed a hybrid heterojunction comprising of Bi2WO6, reduced graphene oxide, and g-C3N4 (BWO/RGO/CN) with a 2D/2D/2D configuration for efficient...
2D/2D/2D architecture g-CN Hybrid heterojunction Solar energy conversion Z-scheme charge transfer /dk/atira/pure/subjectarea/asjc/1500/1503 name=Catalysis /dk/atira/pure/subjectarea/asjc/2300/2300 name=General Environmental Science /dk/atira/pure/subjectarea/asjc/1500/1508 name=Process Chemistry and Technology
Nonlinear mechanisms in Al and Ti superconducting travelling-wave parametric amplifiers
The underlying nonlinear mechanisms behind the operation of travelling-wave
parametric amplifiers (TWPAs) are important in determining their performance in
terms of added noise, maximum gain, and bandwidth. We describe a method...
Defining the molecular basis of BubR1 kinetochore interactions and APC/C-CDC20 inhibition.
BubR1 is essential for the mitotic checkpoint that prevents aneuploidy in cellular progeny by triggering anaphase delay in response to kinetochores incorrectly/not attached to the mitotic spindle. Here, we define the molecular...
Amino Acid Sequence Anaphase-Promoting Complex-Cyclosome Cdc20 Proteins Cell Cycle Proteins Crystallization Crystallography X-Ray Humans Kinetochores Microtubule-Associated Proteins Microtubules Molecular Sequence Data Protein Conformation Protein Serine-Threonine Kinases Sequence Homology Amino Acid Two-Hybrid System Techniques Ubiquitin-Protein Ligase Complexes
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