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Results: 279
Masato Miyake, Akitoshi Nomura, Atsushi Ogura, Kenji Takehana, Yoshihiro Kitahara, Kazuna Takahara, Kazue Tsugawa, Chinobu Miyamoto, Naoko Miura, Ryosuke Sato, Kiyoe Kurahashi, Heather P Harding, Miho Oyadomari, David Ron, Seiichi Oyadomari
Apr 28, 2016
Understanding the role of eco-evolutionary feedbacks in host-parasite coevolution
It is widely recognised that eco-evolutionary feedbacks can have important implications for evolution. However, many models of host-parasite coevolution omit eco-evolutionary feedbacks for the sake of simplicity, typically by...
Why are patients dissatisfied following a total knee replacement? A systematic review
Naoki Nakano, Haitham Shoman, Fernando Olavarria, Tomoyuki Matsumoto, Ryosuke Kuroda, Vikas Khanduja
Oct 23, 2020
Understanding the role of eco-evolutionary feedbacks in host-parasite coevolution
It is widely recognised that eco-evolutionary feedbacks can have important implications for evolution. However, many models of host-parasite coevolution omit eco-evolutionary feedbacks for the sake of simplicity, typically by...
Why are patients dissatisfied following a total knee replacement? A systematic review.
Naoki Nakano, Haitham Shoman, Fernando Olavarria, Tomoyuki Matsumoto, Ryosuke Kuroda, Vikas Khanduja
Nov 26, 2020
BACKGROUND: Although total knee replacement (TKR) is an effective intervention for end-stage arthritis of the knee, a significant number of patients remain dissatisfied following this procedure. Our aim was to identify and...
Why are patients dissatisfied following a total knee replacement? A systematic review
Naoki Nakano, Haitham Shoman, Fernando Olavarria, Tomoyuki Matsumoto, Ryosuke Kuroda, Vikas Khanduja
Jul 28, 2021
Connectivity Gradient in the Human Left Inferior Frontal Gyrus
Takuro Nakae, Riki Matsumoto, Takeharu Kunieda, Yoshiki Arakawa, Katsuya Kobayashi, Akihiro Shimotake, Yukihiro Yamao, Takayuki Kikuchi, Toshihiko Aso, Masao Matsuhashi, Kazumichi Yoshida, Akio Ikeda, Ryosuke Takahashi, Matthew A Lambon Ralph, Susumu Miyamoto
Mar 11, 2020
In the dual-stream model of language processing, the exact connectivity of the ventral stream to the anterior temporal lobe remains elusive. To investigate the connectivity between the inferior frontal gyrus (IFG) and the...
Renin-a in the Subfornical Organ Plays a Critical Role in the Maintenance of Salt-Sensitive Hypertension.
Silvana G Cooper, Lucas AC Souza, Caleb J Worker, Ariana Julia B Gayban, Sophie Buller, Ryosuke Satou, Yumei Feng Earley
Oct 24, 2022
The brain renin-angiotensin system plays important roles in blood pressure and cardiovascular regulation. There are two isoforms of prorenin in the brain: the classic secreted form (prorenin/sREN) encoded by renin-a, and an...
NAD(P)H oxidase angiotensin receptor autonomic control Renin-Angiotensin System salt-sensitive hypertension Angiotensin II Animals Cholinergic Agents Desoxycorticosterone Acetate Hypertension Mice NADPH Oxidase 2 RNA Messenger Renin Sodium Chloride sodium Dietary Subfornical Organ Tyrosine 3-Monooxygenase
Evidence for a deep, distributed and dynamic code for animacy in human ventral anterior temporal cortex.
Timothy T Rogers, Christopher R Cox, Qihong Lu, Akihiro Shimotake, Takayuki Kikuchi, Takeharu Kunieda, Susumu Miyamoto, Ryosuke Takahashi, Akio Ikeda, Riki Matsumoto, Matthew A Lambon Ralph
Jan 06, 2022
Benign preparation of aqueous core poly lactic-co-glycolic acid (PLGA) microcapsules.
Poly lactic-co-glycolic acid (PLGA) has attracted considerable attention as a polymer for drug delivery carriers. However, the hydrophobic property of PLGA often leads to the use of harmful organic solvents and poor...
Renin-a in the Subfornical Organ Plays a Critical Role in the Maintenance of Salt-Sensitive Hypertension.
Silvana G Cooper, Lucas AC Souza, Caleb J Worker, Ariana Julia B Gayban, Sophie Buller, Ryosuke Satou, Yumei Feng Earley
Aug 25, 2022
The brain renin-angiotensin system plays important roles in blood pressure and cardiovascular regulation. There are two isoforms of prorenin in the brain: the classic secreted form (prorenin/sREN) encoded by renin-a, and an...
Activated Microglia Desialylate and Phagocytose Cells via Neuraminidase, Galectin-3, and Mer Tyrosine Kinase
Observed and Modeled Mountain Waves from the Surface to the Mesosphere Near the Drake Passage
Christopher Kruse, M. Joan Alexander, Lars Hoffmann, Annelize van Niekerk, Inna Polichtchouk, Julio Bacmeister, Laura A. Holt, Riwal Plougonven, Petr Sacha, Corwin Wright, Kaoru Sato, Ryosuke Shibuya, Sonja Gisinger, Manfred Ern, Catrin Meyer, Olaf Stein
Apr 01, 2022
Four state-of-the-science numerical weather prediction (NWP) models were used to perform mountain wave (MW)-resolving hindcasts over the Drake Passage of a 10-day period in 2010 with numerous observed MW cases. The Integrated...
dynamics Forcing Gravity waves Instrumentation/sensors Mesoscale processes Middle atmosphere Model comparison Model errors Model evaluation/performance momentum Mountain waves Orographic effects Parameterization Regional models Satellite observations Spectral analysis/models/distribution Stratosphere-troposphere coupling Subgrid-scale processes /dk/atira/pure/subjectarea/asjc/1900/1902 name=Atmospheric Science /dk/atira/pure/sustainabledevelopmentgoals/climate_action name=SDG 13 - Climate Action
Evidence for a deep, distributed and dynamic code for animacy in human ventral anterior temporal cortex.
Timothy T Rogers, Christopher R Cox, Qihong Lu, Akihiro Shimotake, Takayuki Kikuchi, Takeharu Kunieda, Susumu Miyamoto, Ryosuke Takahashi, Akio Ikeda, Riki Matsumoto, Matthew Lambon Ralph
Oct 28, 2021
Observed and Modeled Mountain Waves from the Surface to the Mesosphere Near the Drake Passage
Christopher Kruse, M. Joan Alexander, Lars Hoffmann, Annelize van Niekerk, Inna Polichtchouk, Julio Bacmeister, Laura A. Holt, Riwal Plougonven, Petr Sacha, Corwin Wright, Kaoru Sato, Ryosuke Shibuya, Sonja Gisinger, Manfred Ern, Catrin Meyer, Olaf Stein
Apr 01, 2022
Four state-of-the-science numerical weather prediction (NWP) models were used to perform mountain wave (MW)-resolving hindcasts over the Drake Passage of a 10-day period in 2010 with numerous observed MW cases. The Integrated...
dynamics Forcing Gravity waves Instrumentation/sensors Mesoscale processes Middle atmosphere Model comparison Model errors Model evaluation/performance momentum Mountain waves Orographic effects Parameterization Regional models Satellite observations Spectral analysis/models/distribution Stratosphere-troposphere coupling Subgrid-scale processes /dk/atira/pure/subjectarea/asjc/1900/1902 name=Atmospheric Science /dk/atira/pure/sustainabledevelopmentgoals/climate_action name=SDG 13 - Climate Action
Ancient Jomon genome sequence analysis sheds light on migration patterns of early East Asian populations
Takashi Gakuhari, Shigeki Nakagome, Simon Rasmussen, Morten E. Allentoft, Takehiro Sato, Thorfinn Korneliussen, Blánaid Ní Chuinneagáin, Hiromi Matsumae, Kae Koganebuchi, Ryan Schmidt, Souichiro Mizushima, Osamu Kondo, Nobuo Shigehara, Minoru Yoneda, Ryosuke Kimura, Hajime Ishida, Tadayuki Masuyama, Yasuhiro Yamada, Atsushi Tajima, Hiroki Shibata, Atsushi Toyoda, Toshiyuki Tsurumoto, Tetsuaki Wakebe, Hiromi Shitara, Tsunehiko Hanihara, Eske Willerslev, Martin Sikora, Hiroki Oota
Aug 25, 2020
Ancient Jomon genome sequence analysis sheds light on migration patterns of early East Asian populations
Takashi Gakuhari, Shigeki Nakagome, Simon Rasmussen, Morten E. Allentoft, Takehiro Sato, Thorfinn Korneliussen, Blánaid Ní Chuinneagáin, Hiromi Matsumae, Kae Koganebuchi, Ryan Schmidt, Souichiro Mizushima, Osamu Kondo, Nobuo Shigehara, Minoru Yoneda, Ryosuke Kimura, Hajime Ishida, Tadayuki Masuyama, Yasuhiro Yamada, Atsushi Tajima, Hiroki Shibata, Atsushi Toyoda, Toshiyuki Tsurumoto, Tetsuaki Wakebe, Hiromi Shitara, Tsunehiko Hanihara, Eske Willerslev, Martin Sikora, Hiroki Oota
Aug 26, 2021
Galectin-3 released in response to traumatic brain injury acts as an alarmin orchestrating brain immune response and promoting neurodegeneration
PK Yip, A Carrillo-Jimenez, P King, A Vilalta, K Nomura, CC Chau, AMS Egerton, Z-H Liu, AJ Shetty, JL Tremoleda, M Davies, T Deierborg, JV Priestley, GC Brown, AT Michael-Titus, JL Venero, MA Burguillos
Apr 19, 2017
Biallelic UFM1 and UFC1 mutations expand the essential role of ufmylation in brain development.
Michael S Nahorski, Sateesh Maddirevula, Ryosuke Ishimura, Saud Alsahli, Angela F Brady, Anaïs Begemann, Tsunehiro Mizushima, Francisco J Guzmán-Vega, Miki Obata, Yoshinobu Ichimura, Hessa S Alsaif, Shams Anazi, Niema Ibrahim, Firdous Abdulwahab, Mais Hashem, Dorota Monies, Mohamed Abouelhoda, Brian F Meyer, Majid Alfadhel, Wafa Eyaid, Markus Zweier, Katharina Steindl, Anita Rauch, Stefan T Arold, C Geoffrey Woods, Masaaki Komatsu, Fowzan S Alkuraya
Apr 30, 2018
The post-translational modification of proteins through the addition of UFM1, also known as ufmylation, plays a critical developmental role as revealed by studies in animal models. The recent finding that biallelic mutations in...
Ancient Jomon genome sequence analysis sheds light on migration patterns of early East Asian populations.
Takashi Gakuhari, Shigeki Nakagome, Simon Rasmussen, Morten E Allentoft, Takehiro Sato, Thorfinn Korneliussen, Blánaid Ní Chuinneagáin, Hiromi Matsumae, Kae Koganebuchi, Ryan Schmidt, Souichiro Mizushima, Osamu Kondo, Nobuo Shigehara, Minoru Yoneda, Ryosuke Kimura, Hajime Ishida, Tadayuki Masuyama, Yasuhiro Yamada, Atsushi Tajima, Hiroki Shibata, Atsushi Toyoda, Toshiyuki Tsurumoto, Tetsuaki Wakebe, Hiromi Shitara, Tsunehiko Hanihara, Eske Willerslev, Martin Sikora, Hiroki Oota
Oct 12, 2020
Anatomically modern humans reached East Asia more than 40,000 years ago. However, key questions still remain unanswered with regard to the route(s) and the number of wave(s) in the dispersal into East Eurasia. Ancient genomes at...
Rare Protein-Truncating Variants in APOB, Lower Low-Density Lipoprotein Cholesterol, and Protection Against Coronary Heart Disease.
Gina M Peloso, Akihiro Nomura, Amit V Khera, Mark Chaffin, Hong-Hee Won, Diego Ardissino, John Danesh, Heribert Schunkert, James G Wilson, Nilesh Samani, Jeanette Erdmann, Ruth McPherson, Hugh Watkins, Danish Saleheen, Shane McCarthy, Tanya M Teslovich, Joseph B Leader, H Lester Kirchner, Jaume Marrugat, Atsushi Nohara, Masa-Aki Kawashiri, Hayato Tada, Frederick E Dewey, David J Carey, Aris Baras, Sekar Kathiresan
Apr 15, 2019
Phenotypic Consequences of a Genetic Predisposition to Enhanced Nitric Oxide Signaling.
Connor A Emdin, Amit V Khera, Derek Klarin, Pradeep Natarajan, Seyedeh M Zekavat, Akihiro Nomura, Mary Haas, Krishna Aragam, Diego Ardissino, James G Wilson, Heribert Schunkert, Ruth McPherson, Hugh Watkins, Roberto Elosua, Matthew J Bown, Nilesh J Samani, Usman Baber, Jeanette Erdmann, Padhraig Gormley, Aarno Palotie, Nathan O Stitziel, Namrata Gupta, John Danesh, Danish Saleheen, Stacey Gabriel, Sekar Kathiresan
Jan 19, 2018
BACKGROUND: Nitric oxide signaling plays a key role in the regulation of vascular tone and platelet activation. Here, we seek to understand the impact of a genetic predisposition to enhanced nitric oxide signaling on risk for...
cardiovascular disease Genetics Nitric oxide nitric oxide synthase blood pressure Coronary Disease Genetic Association Studies Genetic Predisposition to Disease Humans Mutation Nitric oxide Nitric Oxide Synthase Type III Peripheral Arterial Disease Phenotype Polymorphism Single Nucleotide Protective factors Risk Factors Signal Transduction Soluble Guanylyl Cyclase stroke
Methods for biogeochemical studies of sea ice
LA Miller, F Fripiat, BGT Else, JS Bowman, KA Brown, RE Collins, M Ewert, A Fransson, M Gosselin, D Lannuzel, KM Meiners, C Michel, J Nishioka, D Nomura, S Papadimitriou, LM Russell, LL Sørensen, DN Thomas, JL Tison, MA Van Leeuwe, M Vancoppenolle, EW Wolff, J Zhou
Mar 19, 2015
Heterozygous ABCG5 Gene Deficiency and Risk of Coronary Artery Disease.
Akihiro Nomura, Connor A Emdin, Hong Hee Won, Gina M Peloso, Pradeep Natarajan, Diego Ardissino, John Danesh, Heribert Schunkert, Adolfo Correa, Matthew J Bown, Nilesh J Samani, Jeanette Erdmann, Ruth McPherson, Hugh Watkins, Danish Saleheen, Roberto Elosua, Masa-Aki Kawashiri, Hayato Tada, Namrata Gupta, Svati H Shah, Daniel J Rader, Stacey Gabriel, Amit V Khera, Sekar Kathiresan
Dec 17, 2020
Coronary Artery Disease Lipids Odds Ratio Pedigree prevalence ATP Binding Cassette Transporter Subfamily G Member 5 ATP Binding Cassette Transporter Subfamily G Member 8 Adult Case-Control Studies Cholesterol LDL Coronary Artery Disease Female Heterozygote Humans Hypercholesterolemia Intestinal Diseases Lipid Metabolism Inborn Errors Lipoproteins Loss of Function Mutation Male Middle Aged Odds Ratio Phytosterols Risk Factors Sitosterols
The 3rd DBCLS BioHackathon
Toshiaki Katayama, Mark D Wilkinson, Gos Micklem, Shuichi Kawashima, Atsuko Yamaguchi, Mitsuteru Nakao, Yasunori Yamamoto, Shinobu Okamoto, Kenta Oouchida, Hong-Woo Chun, Jan Aerts, Hammad Afzal, Erick Antezana, Kazuharu Arakawa, Bruno Aranda, Francois Belleau, Jerven Bolleman, Raoul Jp Bonnal, Brad Chapman, Peter Ja Cock, Tore Eriksson, Paul Mk Gordon, Naohisa Goto, Kazuhiro Hayashi, Heiko Horn, Ryosuke Ishiwata, Eli Kaminuma, Arek Kasprzyk, Hideya Kawaji, Nobuhiro Kido, Young Joo Kim, Akira R Kinjo, Fumikazu Konishi, Kyung-Hoon Kwon, Alberto Labarga, Anna-Lena Lamprecht, Yu Lin, Pierre Lindenbaum, Luke McCarthy, Hideyuki Morita, Katsuhiko Murakami, Koji Nagao, Kozo Nishida, Kunihiro Nishimura, Tatsuya Nishizawa, Soichi Ogishima, Keiichiro Ono, Kazuki Oshita, Keun-Joon Park, Pjotr Prins, Taro L Saito, Matthias Samwald, Venkata P Satagopam, Yasumasa Shigemoto, Richard Smith, Andrea Splendiani, Hideaki Sugawara, James Taylor, Rutger A Vos, David Withers, Chisato Yamasaki, Christian M Zmasek, Shoko Kawamoto, Kosaku Okubo, Kiyoshi Asai, Toshihisa Takagi
Mar 06, 2013
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