Three highly conserved, multisubunit RNA polymerase (RNAP) enzymes, RNAPs I, II, and III, transcribe the eukaryotic nuclear genome (reviewed by Cramer et al. 2008, Vannini and Cramer 2012, Griesenbeck et al. 2017, Cramer 2019)....
UDP-glycosyltransferases (UGTs) are important conjugation enzymes found in all kingdoms of life, catalyzing a sugar conjugation with small lipophilic compounds and playing a crucial role in detoxification and homeostasis. The...
UDP-glycosyltransferases (UGTs) are important conjugation enzymes found in all kingdoms of life, catalyzing a sugar conjugation with small lipophilic compounds and playing a crucial role in detoxification and homeostasis. The...
The catalytic activities of enzymes can be described using Gene Ontology (GO) terms and Enzyme Commission (EC) numbers. These annotations are available from numerous biological databases and are routinely accessed by researchers...
Moderator: Marian Dolan (USA)
Panelists:
Sonja Greiner (Europa Cantat, Germany)
Ann Meier Baker (Chorus America, USA)
Fred Sj?berg (International Federation for Choral Music, Sweden)
Patricia Abbott (CAMMAC and...
Moderator: Marian Dolan (USA)
Panelists:
Sonja Greiner (Europa Cantat, Germany)
Ann Meier Baker (Chorus America, USA)
Fred Sj?berg (International Federation for Choral Music, Sweden)
Patricia Abbott (CAMMAC and...
The neprilysin (M13) family of metalloendopeptidases comprises highly conserved ectoenzymes that cleave and thereby inactivate many physiologically relevant peptides in the extracellular space. Impaired neprilysin activity is...
Brief summaries describing the function of each gene's product(s) are of great value to the research community, especially when interpreting genome-wide studies that reveal changes to hundreds of genes. However, manually writing...
Over the last ten years, results from [48], [49], [22], and [47] decomposing high-frequency Helmholtz solutions into “low”- and “high”-frequency components have had a large impact in the numerical analysis of the Helmholtz...
Over the last ten years, results from [48], [49], [22], and [47] decomposing high-frequency Helmholtz solutions into “low”- and “high”-frequency components have had a large impact in the numerical analysis of the Helmholtz...
DNA synthesis during replication or repair is a fundamental cellular process that is catalyzed by a set of evolutionary conserved polymerases. Despite a large body of research, the DNA polymerases of Drosophila melanogaster have...
FlyBase (flybase.org) is a knowledge base that supports the community of researchers that use the fruit fly, Drosophila melanogaster, as a model organism. The FlyBase team curates and organizes a diverse array of genetic...
Argument Metrological techniques to establish shared quantitative measures have often been seen as signs of rational modernization. The cases considered here show instead the close relation of such techniques with antiquarian...
BACKGROUND: This study aimed to compare and externally validate risk scores developed to predict incident colorectal cancer (CRC) that include variables routinely available or easily obtainable via self-completed questionnaire....