Search
Results: 915
Brain-Penetrating Histone Deacetylase Inhibitor RG2833 Reduces the Viability of Human Malignant Melanoma Cell Lines SK-MEL-5 and SK-MEL-28 in vitro
Lauren Green
Jan 01, 0001
Histone deacetylases (HDACs) play an important role in the epigenetic control of gene expression in both normal and cancer cells. Previous studies have demonstrated that pharmaceutical inhibition of HDACs can kill and/or...
Published by: Winthrop University
Chan-Vese Reformulation for Selective Image Segmentation.
Selective segmentation involves incorporating user input to partition an image into foreground and background, by discriminating between objects of a similar type. Typically, such methods involve introducing additional...
Validation of Performance Homogeneity of Chan-Vese Model on Selected Tumour Cells
This study aims to analyze the Chan-Vese model's performance using a variety of tumor images. The processes involve the tumors' segmentation, detecting the tumors, identifying the segmented tumor region, and extracting the...
Published by: IGI Global Scientific Publishing
The ‘ownership’ of science
Dr Catherine Rhodes is a research fellow at the Institute for Science, Ethics and Innovation specialising in the international regulations relevant to control of biotechnology. Professor John Harris is director of the Institute...
Brain-Penetrating Histone Deacetylase Inhibitor RG2833: A Potential Malignant Melanoma Growth Suppressor
Histone deacetylases (HDACs) play an important role in the epigenetic control of gene expression in both normal and cancer cells. Previous studies have demonstrated that pharmaceutical inhibition of HDACs can kill and/or...
Published by: Winthrop University
Uncovering Regulators of Whole-Body Metabolism by Chemoproteomic Profiling of the Adipocyte Secretome
Chan Hee J Choi
Jan 01, 0001
A major threat to human health, obesity is associated with increased risk of cardiometabolic complications such as cardiovascular disease, type 2 diabetes, hypertension, and many types of cancers. Whereas white adipocytes...
Published by: Rockefeller University
Supernumerary kidneys
Peter Rehder, Rafael Rehwald, Julia M Böhm, Astrid E Grams, Alexander Loizides, Marco Pedrini, Jannik Stühmeier, Bernhard Glodny
Oct 16, 2020
BACKGROUND: A supernumerary kidney (SK) is an additional kidney with its own capsule and blood supply that is not fused with the ipsilateral kidney (IK). Because individual case reports indicate a high morbidity rate, the aim of...
Tuning of Neuronal Excitation by a Brain Specific Microrna MIR-128: From Targets to Behavior
Chan Lek Tan
Jan 01, 0001
MicroRNAs constitute a vital new component of our evolving understanding of regulatory mechanisms that shape cellular gene expression. As ubiquitous regulators of protein translation, microRNAs have a unique regulatory function...
Published by: Rockefeller University
Mutational landscape of normal epithelial cells in Lynch Syndrome patients.
Bernard CH Lee, Philip S Robinson, Tim HH Coorens, Helen HN Yan, Sigurgeir Olafsson, Henry Lee-Six, Mathijs A Sanders, Hoi Cheong Siu, James Hewinson, Sarah SK Yue, Wai Yin Tsui, Annie SY Chan, Anthony KW Chan, Siu Lun Ho, Peter J Campbell, Inigo Martincorena, Simon JA Buczacki, Siu Tsan Yuen, Suet Yi Leung, Michael R Stratton
Jun 29, 2022
Lynch Syndrome (LS) is an autosomal dominant disease conferring a high risk of colorectal cancer due to germline heterozygous mutations in a DNA mismatch repair (MMR) gene. Although cancers in LS patients show elevated somatic...
Controversial Issues in Arthroscopic Surgery for Femoroacetabular Impingement.
Femoroacetabular impingement (FAI) is a common cause of painful hip in the young and middle-aged population. This condition frequently leads to a labral tear, damage of acetabular cartilage, and secondary arthritis of the hip....
Issue Information - TOC
SK Williams
Oct 18, 2018
Despite recent scholarship historians still know relatively little about the dynamics of the maintenance of illegitimate children under the old poor law. This article examines the affiliation system in Southwark and Lambeth...
Statistical Signal Properties of the Pressure-Reactivity Index (PRx)
Objectives: The pressure-reactivity index (PRx) is defined in terms of the moving correlation
coefficient between intracranial pressure (ICP) and mean arterial pressure (MAP) and is a
measure of cerebral autoregulation ability....
Does Knowledge Really Help?
Drawing on the self-determination theory, this study explored the effect of three kinds of low-carbon knowledge (LCB), including system knowledge (SK), action-related knowledge (AK), and effectiveness knowledge (EK), on college...
Published by: IGI Global Scientific Publishing
The Lantern Vol. 65, No. 1, Fall 1997
Joe Catalfano, Brian Hamrick, Janel Reppert, Paul Guidry, Jennifer Herbst, Andrew Gerchak, Jessica Demers, Tom Howard, Larry Santucci, Lyndsay Petersen, Amanda Chiampi, Tom Howard, Matt Klinger, Oana Nechita, Dennis Cormac McCarthy
Jan 01, 0001
The Substitute Style The Greatest of These The No-Zone The Smell of Flowers The Wine Cellar Last Rites The Missing Sock In Loving Memory New Jersey Let's Play a Game Track Eleven U Cab Chan Kina ...
Ursinus College Collegeville Pennsylvania Lantern Literary Magazine poetry fiction Creative Nonfiction Arts and Humanities Creative Writing fiction illustration Nonfiction poetry
Published by: Ursinus College
Evaluation of Diagnostic Performance of Machine Learning Algorithms to Classify the Fetal Heart Rate Baseline From Cardiotocograph
Cardiotocography (CTG) is the widely used cost-effective, non-invasive technique to monitor the fetal heart and mother’s uterine contraction pressure to assess the wellbeing of the fetus. The most important parameters of fetal...
Published by: IGI Global Scientific Publishing
Mutational landscape of normal epithelial cells in Lynch Syndrome patients.
Bernard CH Lee, Philip S Robinson, Tim HH Coorens, Helen HN Yan, Sigurgeir Olafsson, Henry Lee-Six, Mathijs A Sanders, Hoi Cheong Siu, James Hewinson, Sarah SK Yue, Wai Yin Tsui, Annie SY Chan, Anthony KW Chan, Siu Lun Ho, Peter J Campbell, Inigo Martincorena, Simon JA Buczacki, Siu Tsan Yuen, Suet Yi Leung, Michael R Stratton
May 17, 2022
Lynch Syndrome (LS) is an autosomal dominant disease conferring a high risk of colorectal cancer due to germline heterozygous mutations in a DNA mismatch repair (MMR) gene. Although cancers in LS patients show elevated somatic...
LEAP-GWU-2015
As part of the LEAP-GWU-2015 exercise, a dynamic centrifuge test was conducted at the University of Cambridge on a 5° slope of medium dense Ottawa F-65 sand. The model preparation and saturation details are presented in this...
Dynamic and monotonic response of Monopile Foundations for Offshore wind turbines using centrifuge testing
Abstract The seismic response of monopile foundations is a growing area of research as the offshore wind industry expands worldwide, including in earthquake prone regions of the world. This paper...
|
|< |
< |
1 |