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Results: 1140
General tax structures and the Lévy insurance risk model
In the spirit of Albrecher and Hipp (2007), and Albrecher, Renaud, and Zhou (2008) we consider a Levy insurance risk model with tax payments of a more general structure than in the aforementioned papers, which was also...
General tax structures and the Lévy insurance risk model
In the spirit of Albrecher and Hipp (2007), and Albrecher, Renaud, and Zhou (2008) we consider a Levy insurance risk model with tax payments of a more general structure than in the aforementioned papers, which was also...
Insights into azalomycin F assembly-line contribute to evolution-guided polyketide synthase engineering and identification of intermodular recognition.
Guifa Zhai, Yan Zhu, Guo Sun, Fan Zhou, Yangning Sun, Zhou Hong, Chuan Dong, Peter F Leadlay, Kui Hong, Zixin Deng, Fuling Zhou, Yuhui Sun
Feb 09, 2023
Insights into azalomycin F assembly-line contribute to evolution-guided polyketide synthase engineering and identification of intermodular recognition.
Guifa Zhai, Yan Zhu, Guo Sun, Fan Zhou, Yangning Sun, Zhou Hong, Chuan Dong, Peter F Leadlay, Kui Hong, Zixin Deng, Fuling Zhou, Yuhui Sun
Mar 07, 2023
Modular polyketide synthase (PKS) is an ingenious core machine that catalyzes abundant polyketides in nature. Exploring interactions among modules in PKS is very important for understanding the overall biosynthetic process and...
Published by: Nature Communications
Study on Influences of Fringing Reef on Harbor Oscillations Triggered by N-Waves
Influences of topographic variations of the offshore fringing reef on the harbor oscillations excited by incident N-waves with different amplitudes and waveform types are studied for the first time. Both the propagation of...
Fringing-reef topography FUNWAVE-TVD Harbor oscillations N-waves Numerical simulations /dk/atira/pure/subjectarea/asjc/1900/1910 name=Oceanography /dk/atira/pure/subjectarea/asjc/2100/2105 name=Renewable Energy, Sustainability and the Environment /dk/atira/pure/subjectarea/asjc/2200/2212 name=Ocean Engineering /dk/atira/pure/subjectarea/asjc/2200/2210 name=Mechanical Engineering /dk/atira/pure/sustainabledevelopmentgoals/affordable_and_clean_energy name=SDG 7 - Affordable and Clean Energy
Genetic and psychosocial stressors have independent effects on the level of subclinical psychosis
B Pignon, H Peyre, A Ayrolles, JB Kirkbride, S Jamain, A Ferchiou, JR Richard, G Baudin, S Tosato, H Jongsma, L de Haan, I Tarricone, M Bernardo, E Velthorst, M Braca, C Arango, M Arrojo, J Bobes, CM Del-Ben, M Di Forti, C Gayer-Anderson, PB Jones, C La Cascia, A Lasalvia, PR Menezes, D Quattrone, J Sanjuán, JP Selten, A Tortelli, PM Llorca, J van Os, BPF Rutten, RM Murray, C Morgan, M Leboyer, A Szöke, F Schürhoff
Oct 28, 2022
AIMS: Gene x environment (G×E) interactions, i.e. genetic modulation of the sensitivity to environmental factors and/or environmental control of the gene expression, have not been reliably established regarding aetiology of...
The continuity of effect of schizophrenia polygenic risk score and patterns of cannabis use on transdiagnostic symptom dimensions at first-episode psychosis
Diego Quattrone, Ulrich Reininghaus, Alex L Richards, Giada Tripoli, Laura Ferraro, Andrea Quattrone, Paolo Marino, Victoria Rodriguez, Edoardo Spinazzola, Charlotte Gayer-Anderson, Hannah E Jongsma, Peter B Jones, Caterina La Cascia, Daniele La Barbera, Ilaria Tarricone, Elena Bonora, Sarah Tosato, Antonio Lasalvia, Andrei Szöke, Celso Arango, Miquel Bernardo, Julio Bobes, Cristina Marta Del Ben, Paulo Rossi Menezes, Pierre-Michel Llorca, Jose Luis Santos, Julio Sanjuán, Manuel Arrojo, Andrea Tortelli, Eva Velthorst, Steven Berendsen, Lieuwe de Haan, Bart P F Rutten, Michael T Lynskey, Tom P Freeman, James B Kirkbride, Pak C Sham, Michael C O'Donovan, Alastair G Cardno, Evangelos Vassos, Jim van Os, Craig Morgan, Robin M Murray, Cathryn M Lewis, Marta Di Forti
Sep 11, 2021
Diagnostic categories do not completely reflect the heterogeneous expression of psychosis. Using data from the EU-GEI study, we evaluated the impact of schizophrenia polygenic risk score (SZ-PRS) and patterns of cannabis use on...
Published by: Translational psychiatry
The continuity of effect of schizophrenia polygenic risk score and patterns of cannabis use on transdiagnostic symptom dimensions at first-episode psychosis
Diego Quattrone, Ulrich Reininghaus, Alex L. Richards, Giada Tripoli, Laura Ferraro, Andrea Quattrone, Paolo Marino, Victoria Rodriguez, Edoardo Spinazzola, Charlotte Gayer-Anderson, Hannah E. Jongsma, Peter B. Jones, Caterina La Cascia, Daniele La Barbera, Ilaria Tarricone, Elena Bonora, Sarah Tosato, Antonio Lasalvia, Andrei Szöke, Celso Arango, Miquel Bernardo, Julio Bobes, Cristina Marta Del Ben, Paulo Rossi Menezes, Pierre-Michel Llorca, Jose Luis Santos, Julio Sanjuán, Manuel Arrojo, Andrea Tortelli, Eva Velthorst, Steven Berendsen, Lieuwe de Haan, Bart P. F. Rutten, Michael T. Lynskey, Tom P. Freeman, James B. Kirkbride, Pak C. Sham, Michael C. O’Donovan, Alastair G. Cardno, Evangelos Vassos, Jim van Os, Craig Morgan, Robin M. Murray, Cathryn M. Lewis, Marta Di Forti, Kathryn Hubbard, Stephanie Beards, Simona A. Stilo, Mara Parellada, David Fraguas, Marta Rapado Castro, Álvaro Andreu-Bernabeu, Gonzalo López, Mario Matteis, Emiliano González, Manuel Durán-Cutilla, Covadonga M. Díaz-Caneja, Pedro Cuadrado, José Juan Rodríguez Solano, Angel Carracedo, Javier Costas, Emilio Sánchez, Silvia Amoretti, Esther Lorente-Rovira, Paz Garcia-Portilla, Estela Jiménez-López, Nathalie Franke, Daniella van Dam, Fabian Termorshuizen, Elsje van der Ven, Elles Messchaart, Marion Leboyer, Franck Schürhoff, Stéphane Jamain, Grégoire Baudin, Aziz Ferchiou, Baptiste Pignon, Jean-Romain Richard, Thomas Charpeaud, Anne-Marie Tronche, Flora Frijda, Giovanna Marrazzo, Lucia Sideli, Crocettarachele Sartorio, Fabio Seminerio, Camila Marcelino Loureiro, Rosana Shuhama, Mirella Ruggeri, Chiara Bonetto, Doriana Cristofalo, Domenico Berardi, Marco Seri, Giuseppe D’Andrea
Aug 11, 2021
Abstract: Diagnostic categories do not completely reflect the heterogeneous expression of psychosis. Using data from the EU-GEI study, we evaluated the impact of schizophrenia polygenic risk score (SZ-PRS) and patterns of...
Neuregulin 1 Type I Overexpression Is Associated with Reduced NMDA Receptor-Mediated Synaptic Signaling in Hippocampal Interneurons Expressing PV or CCK.
Dimitrios Kotzadimitriou, Wiebke Nissen, Melinda Paizs, Kathryn Newton, Paul J Harrison, Ole Paulsen, Karri Lamsa
May 16, 2018
Hypofunction of N-methyl-d-aspartate receptors (NMDARs) in inhibitory GABAergic interneurons is implicated in the pathophysiology of schizophrenia (SZ), a heritable disorder with many susceptibility genes. However, it is still...
The progression of disorder-specific brain pattern expression in schizophrenia over 9 years.
Johannes Lieslehto, Erika Jääskeläinen, Vesa Kiviniemi, Marianne Haapea, Peter B Jones, Graham K Murray, Juha Veijola, Udo Dannlowski, Dominik Grotegerd, Susanne Meinert, Tim Hahn, Anne Ruef, Matti Isohanni, Peter Falkai, Jouko Miettunen, Dominic B Dwyer, Nikolaos Koutsouleris
Jul 28, 2021
Age plays a crucial role in the performance of schizophrenia vs. controls (SZ-HC) neuroimaging-based machine learning (ML) models as the accuracy of identifying first-episode psychosis from controls is poor compared to chronic...
Published by: NPJ schizophrenia
Study on Influences of Fringing Reef on Harbor Oscillations Triggered by N-Waves
Influences of topographic variations of the offshore fringing reef on the harbor oscillations excited by incident N-waves with different amplitudes and waveform types are studied for the first time. Both the propagation of...
Fringing-reef topography FUNWAVE-TVD Harbor oscillations N-waves Numerical simulations /dk/atira/pure/subjectarea/asjc/1900/1910 name=Oceanography /dk/atira/pure/subjectarea/asjc/2100/2105 name=Renewable Energy, Sustainability and the Environment /dk/atira/pure/subjectarea/asjc/2200/2212 name=Ocean Engineering /dk/atira/pure/subjectarea/asjc/2200/2210 name=Mechanical Engineering /dk/atira/pure/sustainabledevelopmentgoals/affordable_and_clean_energy name=SDG 7 - Affordable and Clean Energy
The progression of disorder-specific brain pattern expression in schizophrenia over 9 years
Johannes Lieslehto, Erika Jääskeläinen, Vesa Kiviniemi, Marianne Haapea, Peter B. Jones, Graham K. Murray, Juha Veijola, Udo Dannlowski, Dominik Grotegerd, Susanne Meinert, Tim Hahn, Anne Ruef, Matti Isohanni, Peter Falkai, Jouko Miettunen, Dominic B. Dwyer, Nikolaos Koutsouleris
Jun 14, 2021
Abstract: Age plays a crucial role in the performance of schizophrenia vs. controls (SZ-HC) neuroimaging-based machine learning (ML) models as the accuracy of identifying first-episode psychosis from controls is poor compared to...
The progression of disorder-specific brain pattern expression in schizophrenia over 9 years.
Johannes Lieslehto, Erika Jääskeläinen, Vesa Kiviniemi, Marianne Haapea, Peter B Jones, Graham K Murray, Juha Veijola, Udo Dannlowski, Dominik Grotegerd, Susanne Meinert, Tim Hahn, Anne Ruef, Matti Isohanni, Peter Falkai, Jouko Miettunen, Dominic B Dwyer, Nikolaos Koutsouleris
Jul 21, 2021
Age plays a crucial role in the performance of schizophrenia vs. controls (SZ-HC) neuroimaging-based machine learning (ML) models as the accuracy of identifying first-episode psychosis from controls is poor compared to chronic...
Research on supporting mechanism of ancillary service of PV system to grid energy efficiency based on multi-time and space-time operation.
Under the background of high-energy penetration of new energy into the power grid, this paper takes the ancillary service capability of photovoltaic energy integrated into the grid as the starting point and builds a photovoltaic...
No Evolution in the Half-mass Radius of Milky Way-type Galaxies over the Last 10 Gyr
Abstract
The Milky Way (MW) galaxy is in focus, thanks to new observational data. Here we shed new light on the MW’s past by studying the structural evolution of MW progenitors...
Cortical and subcortical neuroanatomical signatures of schizotypy in 3004 individuals assessed in a worldwide ENIGMA study.
Matthias Kirschner, Benazir Hodzic-Santor, Mathilde Antoniades, Igor Nenadic, Tilo Kircher, Axel Krug, Tina Meller, Dominik Grotegerd, Alex Fornito, Aurina Arnatkeviciute, Mark A Bellgrove, Jeggan Tiego, Udo Dannlowski, Katharina Koch, Carina Hülsmann, Harald Kugel, Verena Enneking, Melissa Klug, Elisabeth J Leehr, Joscha Böhnlein, Marius Gruber, David Mehler, Pamela DeRosse, Ashley Moyett, Bernhard T Baune, Melissa Green, Yann Quidé, Christos Pantelis, Raymond Chan, Yi Wang, Ulrich Ettinger, Martin Debbané, Melodie Derome, Christian Gaser, Bianca Besteher, Kelly Diederen, Tom J Spencer, Paul Fletcher, Wulf Rössler, Lukasz Smigielski, Veena Kumari, Preethi Premkumar, Haeme RP Park, Kristina Wiebels, Imke Lemmers-Jansen, James Gilleen, Paul Allen, Petya Kozhuharova, Jan-Bernard Marsman, Irina Lebedeva, Alexander Tomyshev, Anna Mukhorina, Stefan Kaiser, Anne-Kathrin Fett, Iris Sommer, Sanne Schuite-Koops, Casey Paquola, Sara Larivière, Boris Bernhardt, Alain Dagher, Phillip Grant, Theo GM van Erp, Jessica A Turner, Paul M Thompson, André Aleman, Gemma Modinos
Apr 29, 2022
Neuroanatomical abnormalities have been reported along a continuum from at-risk stages, including high schizotypy, to early and chronic psychosis. However, a comprehensive neuroanatomical mapping of schizotypy remains to be...
Research on supporting mechanism of ancillary service of PV system to grid energy efficiency based on multi-time and space-time operation.
Under the background of high-energy penetration of new energy into the power grid, this paper takes the ancillary service capability of photovoltaic energy integrated into the grid as the starting point and builds a photovoltaic...
Harmonic Analyses of Hydrodynamic Characteristics for Gap Resonance Between Fixed Box and Vertical Wall
Two marine structures arranged side by side with a narrow gap may suffer from violent free-surface resonance, which would cause green water on deck, dramatically raise hydrodynamic loads on structures and seriously threaten...
Gap resonance harmonic analyses OpenFOAM® resonant wave height Wave loads /dk/atira/pure/subjectarea/asjc/1900/1910 name=Oceanography /dk/atira/pure/subjectarea/asjc/2100/2105 name=Renewable Energy, Sustainability and the Environment /dk/atira/pure/subjectarea/asjc/2200/2212 name=Ocean Engineering /dk/atira/pure/subjectarea/asjc/2200/2210 name=Mechanical Engineering /dk/atira/pure/sustainabledevelopmentgoals/clean_water_and_sanitation name=SDG 6 - Clean Water and Sanitation /dk/atira/pure/sustainabledevelopmentgoals/affordable_and_clean_energy name=SDG 7 - Affordable and Clean Energy /dk/atira/pure/sustainabledevelopmentgoals/life_below_water name=SDG 14 - Life Below Water
Budding-like division of all-aqueous emulsion droplets modulated by networks of protein nanofibrils.
Yang Song, Thomas CT Michaels, Qingming Ma, Zhou Liu, Hao Yuan, Shuichi Takayama, Tuomas PJ Knowles, Ho Cheung Shum
Sep 29, 2018
Networks of natural protein nanofibrils, such as cytoskeletal filaments, control the shape and the division of cells, yet mimicking this functionality in a synthetic setting has proved challenging. Here, we demonstrate that...
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