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Increased platelet adhesion and thrombus formation in a mouse model of Alzheimer's disease
Vascular dysfunctions and Alzheimer's disease show significant similarities and overlaps. Cardiovascular risk factors (hypercholesterolemia, hypertension, obesity, atherosclerosis and diabetes) increase the risk of vascular...
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Increased platelet adhesion and thrombus formation in a mouse model of Alzheimer's disease
Vascular dysfunctions and Alzheimer's disease show significant similarities and overlaps. Cardiovascular risk factors (hypercholesterolemia, hypertension, obesity, atherosclerosis and diabetes) increase the risk of vascular...
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Amyloid β-peptide-dependent activation of human platelets

Alzheimer's disease is associated with the accumulation of Aβ (amyloid β)-peptides in the brain. Besides their cytotoxic effect on neurons, Aβ-peptides are thought to be responsible for the atherothrombotic complications...

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Amyloid β-peptide-dependent activation of human platelets

Alzheimer's disease is associated with the accumulation of Aβ (amyloid β)-peptides in the brain. Besides their cytotoxic effect on neurons, Aβ-peptides are thought to be responsible for the atherothrombotic complications...

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Nonlinear elastic multi-path reciprocal method for damage localisation in composite materials
Nonlinear ultrasonic techniques rely on the measurement of nonlinear elastic effects caused by the interaction of ultrasonic waves with the material damage, and have shown high sensitivity to detect micro-cracks and defects in...
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Mesenchymal Stem Cells as Promoters, Enhancers, and Playmakers of the Translational Regenerative Medicine.
Since their first isolation and characterization by Friedenstein et al. in 1974 [1], mesenchymal stem cells (MSCs) were proven essential for tissue regeneration and homeostasis.
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Inhibition of the Eukaryotic 80S Ribosome as a Potential Anticancer Therapy
Protein biosynthesis is a vital process for all kingdoms of life. The ribosome is the massive ribonucleoprotein machinery that reads the genetic code, in the form of messenger RNA (mRNA), to produce proteins. The mechanism of...
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Inhibition of the Eukaryotic 80S Ribosome as a Potential Anticancer Therapy
Protein biosynthesis is a vital process for all kingdoms of life. The ribosome is the massive ribonucleoprotein machinery that reads the genetic code, in the form of messenger RNA (mRNA), to produce proteins. The mechanism of...
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Nonlinear elastic multi-path reciprocal method for damage localisation in composite materials
Nonlinear ultrasonic techniques rely on the measurement of nonlinear elastic effects caused by the interaction of ultrasonic waves with the material damage, and have shown high sensitivity to detect micro-cracks and defects in...
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Recent advances of HCI in decision-making tasks for optimized clinical workflows and precision medicine.
The ever-increasing amount of biomedical data is enabling new large-scale studies, even though ad hoc computational solutions are required. The most recent Machine Learning (ML) and Artificial Intelligence (AI) techniques have...
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Quantifying the Role of Homophily in Human Cooperation Using Multiplex Evolutionary Game Theory.
Nature shows as human beings live and grow inside social structures. This assumption allows us to explain and explore how it may shape most of our behaviours and choices, and why we are not just blindly driven by instincts: our...
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Neurochemical Correlates of Brain Atrophy in Fibromyalgia Syndrome
(1) Background: Recently, a series of clinical neuroimaging studies on fibromyalgia (FM) have shown a reduction in cortical volume and abnormally high glutamate (Glu) and glutamate + glutamine (Glx) levels in regions associated...
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Heritability of human "directed" functional connectome.
INTRODUCTION: The functional connectivity patterns in the brain are highly heritable; however, it is unclear how genetic factors influence the directionality of such "information flows." Studying the "directionality" of the...
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A Computational Study on Temperature Variations in MRgFUS Treatments Using PRF Thermometry Techniques and Optical Probes
Structural and metabolic imaging are fundamental for diagnosis, treatment and follow-up in oncology. Beyond the well-established diagnostic imaging applications, ultrasounds are currently emerging in the clinical practice as a...
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