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Results: 477
Phosphorylation and Stabilization of PIN1 by JNK Promote Intrahepatic Cholangiocarcinoma Growth.
Alessio Lepore, Pui Man Choy, Nathan CW Lee, Maria Annunziata Carella, Rosy Favicchio, Marco A Briones-Orta, Shannon S Glaser, Gianfranco Alpini, Clive D'Santos, Reuben M Tooze, Mihaela Lorger, Wing-Kin Syn, Athanasios Papakyriakou, Georgios Giamas, Concetta Bubici, Salvatore Papa
Sep 15, 2021
BACKGROUND AND AIMS: Intrahepatic cholangiocarcinoma (ICC) is a highly aggressive type of liver cancer in urgent need of treatment options. Aberrant activation of the c-Jun N-terminal kinase (JNK) pathway is a key feature in ICC...
Animals Antineoplastic Agents Bile Duct Neoplasms Carcinogenesis Cell Line Tumor Cholangiocarcinoma Female Gene Knockdown Techniques Humans MAP Kinase Signaling System Mice Mice Inbred NOD Mice SCID Mitogen-Activated Protein Kinase 8 Mitogen-Activated Protein Kinase 9 NIMA-Interacting Peptidylprolyl Isomerase Phosphorylation RNA Small Interfering Tretinoin Tumor Burden Xenograft Model Antitumor Assays
Hunger Series Begins With Dec. 2 Program on Food Security
Winthrop University
Jan 01, 0001
This series consists of five different programs aimed at informing the campus and community about hunger, which is one of the most important social issues both here at home and throughout the world. The first event will take...
Published by: Winthrop University
Viroplasms
Viroplasms are cytoplasmic, membraneless structures assembled in rotavirus (RV)-infected cells, which are intricately involved in viral replication. Two virus-encoded, non-structural proteins, NSP2 and NSP5, are the main drivers...
Viroplasms
Viroplasms are cytoplasmic, membraneless structures assembled in rotavirus (RV)-infected cells, which are intricately involved in viral replication. Two virus-encoded, non-structural proteins, NSP2 and NSP5, are the main drivers...
Reverse Genetics Rotavirus Replication Cycle Nsp2 liquid-liquid phase separation Viroplasm Protein-Rna Condensates Nsp5 Crispr-Csy4 Genome Editing
Published by: Viruses
Association between self-control and health risk behaviors
Roberta Corradi Astolfi, Maria Alvim Leite, Cassio Henrique Gomide Papa, Marcelo Ryngelblum, Manuel Eisner, Maria Fernanda Tourinho Peres
Sep 20, 2021
Abstract: Background: Self-control (SC) has been consistently found associated with diverse health risk behaviors (HRBs), but little research refers to low- and middle-income countries. Furthermore, there is evidence that some...
Viroplasms
Viroplasms are cytoplasmic, membraneless structures assembled in rotavirus (RV)-infected cells, which are intricately involved in viral replication. Two virus-encoded, non-structural proteins, NSP2 and NSP5, are the main drivers...
Crispr-Csy4 Genome Editing Nsp2 Nsp5 liquid-liquid phase separation Protein-Rna Condensates Replication Cycle Reverse Genetics Rotavirus Viroplasm Animals Capsid Proteins Cytoplasm Cytosol Humans Phosphorylation RNA-Binding Proteins Rotavirus Rotavirus Infections Viral Nonstructural Proteins Viral Replication Compartments Virus Assembly Virus Replication
Sequences in the cytoplasmic tail of SARS-CoV-2 Spike facilitate expression at the cell surface and syncytia formation.
Jérôme Cattin-Ortolá, Lawrence G Welch, Sarah L Maslen, Guido Papa, Leo C James, Sean Munro
Oct 13, 2021
The Spike (S) protein of SARS-CoV-2 binds ACE2 to direct fusion with host cells. S comprises a large external domain, a transmembrane domain, and a short cytoplasmic tail. Understanding the intracellular trafficking of S is...
Genome-wide analysis of ionotropic receptors provides insight into their evolution in Heliconius butterflies.
Victims, bullies and bully-victims
Ana Paula Loch, Roberta Corradi Astolfi, Maria Alvim Leite, Cassio Henrique Gomide Papa, Marcelo Ryngelblum, Manuel Eisner, Maria Fernanda Tourinho Peres
Oct 15, 2020
OBJECTIVES: To estimate the prevalence of self-reported bullying as victims, bullies or bully-victims among 9th grade adolescents in the city of São Paulo, Brazil; to investigate association between bullying with negative health...
Sequences in the cytoplasmic tail of SARS-CoV-2 Spike facilitate expression at the cell surface and syncytia formation
Jérôme Cattin-Ortolá, Lawrence G. Welch, Sarah L. Maslen, Guido Papa, Leo C. James, Sean Munro
Sep 09, 2021
Abstract: The Spike (S) protein of SARS-CoV-2 binds ACE2 to direct fusion with host cells. S comprises a large external domain, a transmembrane domain, and a short cytoplasmic tail. Understanding the intracellular trafficking of...
Nonlinear elastic multi-path reciprocal method for damage localisation in composite materials
Nonlinear ultrasonic techniques rely on the measurement of nonlinear elastic effects caused by the interaction of ultrasonic waves with the material damage, and have shown high sensitivity to detect micro-cracks and defects in...
Association between self-control and health risk behaviors
Roberta Corradi Astolfi, Maria Alvim Leite, Cassio Henrique Gomide Papa, Marcelo Ryngelblum, Manuel Eisner, Maria Fernanda Tourinho Peres
Nov 24, 2021
BACKGROUND: Self-control (SC) has been consistently found associated with diverse health risk behaviors (HRBs), but little research refers to low- and middle-income countries. Furthermore, there is evidence that some HRBs tend...
The Grizzly, September 4, 1987
Jean M. Kiss, Lora L. Hart, E.T. Shrdlu, Karen Singhofen, Richard P. Richter, Chris Goldberg, Jill Theurer, Anne Woodworth, Andrea Power, Craig DiLouie, Steve Gall, Scott McCartney
Jan 01, 0001
Convocation Greets Academic Year Eisenhower Speech Kicks off New Year Land of the Rising Sun "Student Life" Shapes Up Letter: Just Call Me Papa Juan Just When You Thought It was Safe Garrick Joins Resident Director...
Ursinus College Collegeville Pennsylvania newspaper academic convocation Tohoku Gakuin University David Eisenhower Office of Student Life Football cross country field hockey Cathy Garrick Debbie Heil Katherine Hager Michelle Quinlan Evening school Keith Hardman Jeffrey Neslen Elliot Tannenbaum Soccer video rental stores Grateful Dead cultural history Higher Education Liberal Studies Social History United States History
Published by: Ursinus College
Design and development of a heatsink for thermo-electric power harvesting in aerospace applications
In recent years, the growing interest of aerospace companies in wireless structural health monitoring (SHM) systems has led to the research of new energy efficient sources and power harvesting solutions. Among available...
heatsink Power generation thermoeletric /dk/atira/pure/subjectarea/asjc/1700/1711 name=Signal Processing /dk/atira/pure/subjectarea/asjc/2200/2205 name=Civil and Structural Engineering /dk/atira/pure/subjectarea/asjc/3100/3107 name=Atomic and Molecular Physics, and Optics /dk/atira/pure/subjectarea/asjc/2500/2500 name=General Materials Science /dk/atira/pure/subjectarea/asjc/3100/3104 name=Condensed Matter Physics /dk/atira/pure/subjectarea/asjc/2200/2211 name=Mechanics of Materials /dk/atira/pure/subjectarea/asjc/2200/2208 name=Electrical and Electronic Engineering
Design and development of a heatsink for thermo-electric power harvesting in aerospace applications
In recent years, the growing interest of aerospace companies in wireless structural health monitoring (SHM) systems has led to the research of new energy efficient sources and power harvesting solutions. Among available...
heatsink Power generation thermoeletric /dk/atira/pure/subjectarea/asjc/1700/1711 name=Signal Processing /dk/atira/pure/subjectarea/asjc/2200/2205 name=Civil and Structural Engineering /dk/atira/pure/subjectarea/asjc/3100/3107 name=Atomic and Molecular Physics, and Optics /dk/atira/pure/subjectarea/asjc/2500/2500 name=General Materials Science /dk/atira/pure/subjectarea/asjc/3100/3104 name=Condensed Matter Physics /dk/atira/pure/subjectarea/asjc/2200/2211 name=Mechanics of Materials /dk/atira/pure/subjectarea/asjc/2200/2208 name=Electrical and Electronic Engineering
Association between self-control and health risk behaviors
Roberta Corradi Astolfi, Maria Alvim Leite, Cassio Henrique Gomide Papa, Marcelo Ryngelblum, Manuel Eisner, Maria Fernanda Tourinho Peres
Oct 21, 2021
Background
Self-control (SC) has been consistently found associated with diverse health risk behaviors (HRBs), but little research refers to low- and middle-income countries. Furthermore, there is evidence that some HRBs...
Published by: BMC public health
IP6-stabilised HIV capsids evade cGAS/STING-mediated host immune sensing.
HIV-1 uses inositol hexakisphosphate (IP6) to build a metastable capsid capable of delivering its genome into the host nucleus. Here, we show that viruses that are unable to package IP6 lack capsid protection and are detected by...
Principles of RNA recruitment to viral ribonucleoprotein condensates in a segmented dsRNA virus.
Sebastian Strauss, Julia Acker, Guido Papa, Daniel Desirò, Florian Schueder, Alexander Borodavka, Ralf Jungmann
Feb 25, 2023
Mesenchymal Stem Cells as Promoters, Enhancers, and Playmakers of the Translational Regenerative Medicine.
Since their first isolation and characterization by Friedenstein et al. in 1974 [1], mesenchymal stem cells (MSCs) were proven essential for tissue regeneration and homeostasis.
Inhibition of the Eukaryotic 80S Ribosome as a Potential Anticancer Therapy
Protein biosynthesis is a vital process for all kingdoms of life. The ribosome is the massive ribonucleoprotein machinery that reads the genetic code, in the form of messenger RNA (mRNA), to produce proteins. The mechanism of...
Impact source localisation in aerospace composite structures
The most commonly encountered type of damage in aircraft composite structures is caused by low-velocity impacts due to foreign objects such as hail stones, tool drops and bird strikes. Often these events can cause severe...
composite materials Impact localisation wave propagation /dk/atira/pure/subjectarea/asjc/1700/1711 name=Signal Processing /dk/atira/pure/subjectarea/asjc/2200/2205 name=Civil and Structural Engineering /dk/atira/pure/subjectarea/asjc/3100/3107 name=Atomic and Molecular Physics, and Optics /dk/atira/pure/subjectarea/asjc/2500/2500 name=General Materials Science /dk/atira/pure/subjectarea/asjc/3100/3104 name=Condensed Matter Physics /dk/atira/pure/subjectarea/asjc/2200/2211 name=Mechanics of Materials /dk/atira/pure/subjectarea/asjc/2200/2208 name=Electrical and Electronic Engineering
Impact source localisation in aerospace composite structures
The most commonly encountered type of damage in aircraft composite structures is caused by low-velocity impacts due to foreign objects such as hail stones, tool drops and bird strikes. Often these events can cause severe...
composite materials Impact localisation wave propagation /dk/atira/pure/subjectarea/asjc/1700/1711 name=Signal Processing /dk/atira/pure/subjectarea/asjc/2200/2205 name=Civil and Structural Engineering /dk/atira/pure/subjectarea/asjc/3100/3107 name=Atomic and Molecular Physics, and Optics /dk/atira/pure/subjectarea/asjc/2500/2500 name=General Materials Science /dk/atira/pure/subjectarea/asjc/3100/3104 name=Condensed Matter Physics /dk/atira/pure/subjectarea/asjc/2200/2211 name=Mechanics of Materials /dk/atira/pure/subjectarea/asjc/2200/2208 name=Electrical and Electronic Engineering
Visual mate preference evolution during butterfly speciation is linked to neural processing genes
Matteo Rossi, Alexander E. Hausmann, Timothy J. Thurman, Stephen H. Montgomery, Riccardo Papa, Chris D. Jiggins, W. Owen McMillan, Richard M. Merrill
Sep 21, 2020
Abstract: Many animal species remain separate not because their individuals fail to produce viable hybrids but because they “choose” not to mate. However, we still know very little of the genetic mechanisms underlying changes in...
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