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Results: 89
Phenotypic screening reveals TNFR2 as a promising target for cancer immunotherapy.
Geoffrey S Williams, Bina Mistry, Sandrine Guillard, Jane Coates Ulrichsen, Alan M Sandercock, Jun Wang, Andrea González-Muñoz, Julie Parmentier, Chelsea Black, Jo Soden, Jim Freeth, Jelena Jovanović, Rebecca Leyland, Rafia S Al-Lamki, Andrew J Leishman, Steven J Rust, Ross Stewart, Lutz Jermutus, John R Bradley, Vahe Bedian, Viia Valge-Archer, Ralph Minter, Robert W Wilkinson
Jul 20, 2018
TNFR2 cancer immunotherapy Drug Discovery phenotypic screening Regulatory T cell Animals Antineoplastic Agents Cell Line Tumor Drug Screening Assays Antitumor Female HEK293 Cells Humans Immunotherapy Jurkat Cells Mice Inbred BALB C NF-kappa B Neoplasms Neoplasms Experimental Phenotype Receptors Tumor Necrosis Factor Type II Signal Transduction T-Lymphocytes Regulatory
Environmental implications of increased US oil production and liberal growth agenda in post -Paris Agreement era.
Muhammad Shahbaz, Sandrine Kablan, Shawkat Hammoudeh, Muhammad Ali Nasir, Andreas Kontoleon
May 27, 2020
Contextualising on the internationally low oil prices era and historically high oil production in USA and refusal to honour the commitments under Paris Agreement (COP: 21), this study investigates the role of education, oil...
Silica nanoparticles as sources of silicic acid favoring wound healing in vitro.
There is good evidence that certain silicon-containing materials promote would healing and their common feature is the delivery of orthosilicic acid (Si(OH)4) either directly or following metabolism. In this respect, amorphous...
Self-Assembled Molecular Nanowires for High-Performance Organic Transistors.
Luke R Fleet, James Stott, Byron Villis, Salahud Din, Michele Serri, Gabriel Aeppli, Sandrine Heutz, Arokia Nathan
May 09, 2018
While organic semiconductors provide tantalizing possibilities for low-cost, light-weight, flexible electronic devices, their current use in transistors-the fundamental building block-is rather limited as their speed and...
Defining stem cell dynamics and migration during wound healing in mouse skin epidermis.
Mariaceleste Aragona, Sophie Dekoninck, Steffen Rulands, Sandrine Lenglez, Guilhem Mascré, Benjamin D Simons, Cédric Blanpain
Aug 17, 2017
Association between perinatal factors, genetic susceptibility to obesity and age at adiposity rebound in children of the EDEN mother–child cohort
Aminata Hallimat Cissé, Sandrine Lioret, Blandine de Lauzon-Guillain, Anne Forhan, Ken K. Ong, Marie Aline Charles, Barbara Heude
Jul 28, 2021
Abstract: Background: Early adiposity rebound (AR) has been associated with increased risk of overweight or obesity in adulthood. However, little is known about early predictors of age at AR. We aimed to study the role of...
Metalloproteinases ADAM10 and ADAM17 Mediate Migration and Differentiation in Glioblastoma Sphere-Forming Cells.
Elodie J Siney, Alexander Holden, Elizabeth Casselden, Harry Bulstrode, Gareth J Thomas, Sandrine Willaime-Morawek
Apr 12, 2019
Glioblastoma is the most common form of primary malignant brain tumour. These tumours are highly proliferative and infiltrative resulting in a median patient survival of only 14 months from diagnosis. The current treatment...
cancer stem cell Cell Differentiation cell migration Disintegrin Extracellular Matrix glioma ADAM10 Protein ADAM17 Protein Adult Aged Cell Death Cell Differentiation Cell Movement Extracellular Matrix Female Fibronectins Glioblastoma Humans Integrin alpha5beta1 Male Matrix Metalloproteinase Inhibitors Middle Aged Neoplastic Stem Cells Neural Stem Cells Spheroids Cellular
Association between perinatal factors, genetic susceptibility to obesity and age at adiposity rebound in children of the EDEN mother-child cohort.
Aminata Hallimat Cissé, Sandrine Lioret, Blandine de Lauzon-Guillain, Anne Forhan, Ken K Ong, Marie Aline Charles, Barbara Heude
May 24, 2021
BACKGROUND: Early adiposity rebound (AR) has been associated with increased risk of overweight or obesity in adulthood. However, little is known about early predictors of age at AR. We aimed to study the role of perinatal...
Designing an Internet-Based Multidomain Intervention for the Prevention of Cardiovascular Disease and Cognitive Impairment in Older Adults
Mariagnese Barbera, Francesca Mangialasche, Susan Jongstra, Juliette Guillemont, Tiia Ngandu, Cathrien Beishuizen, Nicola Coley, Carol Brayne, Sandrine Andrieu, Edo Richard, Hilkka Soininen, Miia Kivipelto, HATICE study group
Aug 30, 2018
Monitoring morphological changes in 2D monolayer semiconductors using atom-thick plasmonic nanocavities.
Relative effects of postnatal rapid growth and maternal factors on early childhood growth trajectories.
Miaobing Zheng, Steven J Bowe, Kylie D Hesketh, Kristy Bolton, Rachel Laws, Peter Kremer, Ken K Ong, Sandrine Lioret, Elizabeth Denney-Wilson, Karen J Campbell
Feb 22, 2019
BACKGROUND: A range of postnatal and maternal factors influences childhood obesity, but their relative importance remains unclear. This study aimed to assess the relative impact of postnatal rapid growth and maternal factors on...
InFANT program DETERMINANTS growth Infant Maternal Trajectory Australia Body Height Body Mass Index Child Nutritional Physiological Phenomena Child Preschool Female Humans Infant Infant Nutritional Physiological Phenomena Infant Newborn Longitudinal Studies Male Nutrition Surveys Nutritional Status Pediatric Obesity Waist Circumference
Variability of the mechanical properties of hemp concrete
Cesar Niyigena, Sofiane Amziane, Alaa Chateauneuf, Laurent Arnaud, Leticia Bessette, Florence Collet, Christophe Lanos, Gilles Escadeillas, Mike Lawrence, Camille Magniont, Sandrine Marceau, Sara Pavia, Ulrike Peter, Vincent Picandet, Mohammed Sonebi, Peter Walker
Jun 01, 2016
The focus of this study is on statistical analysis of hemp concrete properties. The main objective is to determine statistically the variability of the three main properties, which are: material density, compressive strength and...
Lithium Intercalation in Anatase Titanium Vacancies and the Role of Local Anionic Environment
Jiwei Ma, Wei Li, Benjamin Morgan, Jolanta Światowska, Rita Baddour-Hadjean, Monique Body, Christophe Legein, Olaf Borkiewicz, Sandrine Leclerc, Henri Groult, Frédéric Lantelme, Christel Laberty-Robert, Damien Dambournet
May 08, 2018
The structure of bulk and nondefective compounds is generally described with crystal models built from well mastered techniques such the analysis of an X-ray diffractogram. The presence of defects, such as cationic vacancies...
Bismuth coordination networks containing deferiprone
Andrew D. Burrows, Monika Jurcic, Mary F. Mahon, Sandrine Pierrat, Gavin W. Roffe, Henry J. Windle, John Spencer
Aug 21, 2015
A series of bismuth-dicarboxylate-deferiprone coordination networks have been prepared and structurally characterised. The new compounds have been demonstrated to release the iron overload drug deferiprone on treatment with...
Sensing sociability
Gabriella M Harari, Sandrine R Müller, Clemens Stachl, Rui Wang, Weichen Wang, Markus Bühner, Peter J Rentfrow, Andrew T Campbell, Samuel D Gosling
May 01, 2019
Sociability as a disposition describes a tendency to affiliate with others (vs. be alone). Yet, we know relatively little about how much social behavior people engage in during a typical day. One challenge to documenting social...
Bismuth coordination networks containing deferiprone
Andrew D. Burrows, Monika Jurcic, Mary F. Mahon, Sandrine Pierrat, Gavin W. Roffe, Henry J. Windle, John Spencer
Aug 21, 2015
A series of bismuth-dicarboxylate-deferiprone coordination networks have been prepared and structurally characterised. The new compounds have been demonstrated to release the iron overload drug deferiprone on treatment with...
Exciton-Phonon Interactions Govern Charge-Transfer-State Dynamics in CdSe/CdTe Two-Dimensional Colloidal Heterostructures.
Spatial Distribution and Burden of Emerging Arboviruses in French Guiana.
Sarah Bailly, Dominique Rousset, Camille Fritzell, Nathanaël Hozé, Sarrah Ben Achour, Léna Berthelot, Antoine Enfissi, Jessica Vanhomwegen, Henrik Salje, Sandrine Fernandes-Pellerin, Mona Saout, Anne Lavergne, Jean-Claude Manuguerra, Jean-François Carod, Félix Djossou, Simon Cauchemez, Claude Flamand
Sep 20, 2021
Despite the health, social and economic impact of arboviruses in French Guiana, very little is known about the extent to which infection burden is shared between individuals. We conducted a large multiplexed serological survey...
chikungunya dengue French Guiana Mayaro Zika Arboviruses prevalence studies Adolescent Adult Aged Antibodies Viral Arbovirus Infections Arboviruses Child Child Preschool Cost of Illness Cross-Sectional Studies Demography Female French Guiana Humans Immunoglobulin G Male Middle Aged prevalence Seroepidemiologic Studies Young Adult
Investigating host-microbiome interactions by droplet based microfluidics.
Alexandra S Tauzin, Mariana Rangel Pereira, Liisa D van Vliet, Pierre-Yves Colin, Elisabeth Laville, Jeremy Esque, Sandrine Laguerre, Bernard Henrissat, Nicolas Terrapon, Vincent Lombard, Marion Leclerc, Joël Doré, Florian Hollfelder, Gabrielle Potocki-Veronese
Oct 09, 2020
BACKGROUND: Despite the importance of the mucosal interface between microbiota and the host in gut homeostasis, little is known about the mechanisms of bacterial gut colonization, involving foraging for glycans produced by...
Investigating host-microbiome interactions by droplet based microfluidics
Alexandra S. Tauzin, Mariana Rangel Pereira, Liisa D. Van Vliet, Pierre-Yves Colin, Elisabeth Laville, Jeremy Esque, Sandrine Laguerre, Bernard Henrissat, Nicolas Terrapon, Vincent Lombard, Marion Leclerc, Joël Doré, Florian Hollfelder, Gabrielle Potocki-Veronese
Nov 14, 2020
Investigating host-microbiome interactions by droplet based microfluidics
Alexandra S. Tauzin, Mariana Rangel Pereira, Liisa D. Van Vliet, Pierre-Yves Colin, Elisabeth Laville, Jeremy Esque, Sandrine Laguerre, Bernard Henrissat, Nicolas Terrapon, Vincent Lombard, Marion Leclerc, Joël Doré, Florian Hollfelder, Gabrielle Potocki-Veronese
Oct 02, 2020
Assessing Zika Virus Transmission Within Households During an Outbreak in Martinique, 2015-2016.
Anthony Cousien, Sylvie Abel, Alice Monthieux, Alessio Andronico, Isabelle Calmont, Minerva Cervantes, Raymond Césaire, Pierre Gallian, Xavier de Lamballerie, Cédric Laouénan, Fatiha Najioullah, Sandrine Pierre-François, Mathilde Pircher, Henrik Salje, Quirine A Ten Bosch, André Cabié, Simon Cauchemez
Feb 15, 2021
Since 2015, Zika virus (ZIKV) has caused large epidemics in the Americas. Households are natural targets for control interventions, but quantification of the contribution of household transmission to overall spread is needed to...
Spatial Distribution and Burden of Emerging Arboviruses in French Guiana
Sarah Bailly, Dominique Rousset, Camille Fritzell, Nathanaël Hozé, Sarrah Ben Achour, Léna Berthelot, Antoine Enfissi, Jessica Vanhomwegen, Henrik Salje, Sandrine Fernandes-Pellerin, Mona Saout, Anne Lavergne, Jean-Claude Manuguerra, Jean-François Carod, Félix Djossou, Simon Cauchemez, Claude Flamand
Jul 05, 2021
Despite the health, social and economic impact of arboviruses in French Guiana, very little is known about the extent to which infection burden is shared between individuals. We conducted a large multiplexed serological survey...
Metal-organic frameworks from divalent metals and 1,4-benzenedicarboxylate with bidentate pyridine-N-oxide co-ligands
Alexis S. Munn, Silvia Amabilino, Thomas W. Stevens, Luke M. Daniels, Guy J. Clarkson, Franck Millange, Matthew Lennox, Tina Düren, Sandrine Bourelly, Philip L. Llewellyn, Richard I. Walton
Feb 04, 2015
Two Co2+ metal-organic framework materials, constructed from a combination of 1,4-benzenedicarboxylate (BDC) and either 2,2′-dipyridyl-N-oxide (DPNO) or 2,2′-dipyridyl-N,N′-dioxide (DPNDO), are synthesized under...
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