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Results: 113
Chemical profiling of DNA G-quadruplex-interacting proteins in live cells.
Xiaoyun Zhang, Jochen Spiegel, Sergio Martínez Cuesta, Santosh Adhikari, Shankar Balasubramanian
Aug 02, 2021
DNA-protein interactions regulate critical biological processes. Identifying proteins that bind to specific, functional genomic loci is essential to understand the underlying regulatory mechanisms on a molecular level. Here we...
Published by: Nature chemistry
G-quadruplexes are transcription factor binding hubs in human chromatin
Jochen Spiegel, Sergio Martínez Cuesta, Santosh Adhikari, Robert Hänsel-Hertsch, David Tannahill, Shankar Balasubramanian
Apr 23, 2021
Abstract: Background: The binding of transcription factors (TF) to genomic targets is critical in the regulation of gene expression. Short, double-stranded DNA sequence motifs are routinely implicated in TF recruitment, but many...
Structure and Piezoelectricity Due to B Site Cation Variation in AB<sup>n+</sup>Cl<sub>n+2</sub>Hybrid Histammonium Chlorometallate Materials
Michael Wells, Jacob Hempel, Santosh Adhikari, Qingping Wang, Daniel Allen, Alison Costello, Chris Bowen, Sean Parkin, Christopher Sutton, Aron J. Huckaba
Nov 07, 2022
To provide new insights for understanding the influence of B site cations on the structure in chlorometallate materials of the form ABn+Cln+2, we report novel organic-inorganic hybrid metallates (OIHMs) incorporating...
Structure and Piezoelectricity Due to B Site Cation Variation in AB<sup>n+</sup>Cl<sub>n+2</sub>Hybrid Histammonium Chlorometallate Materials
Michael Wells, Jacob Hempel, Santosh Adhikari, Qingping Wang, Daniel Allen, Alison Costello, Chris Bowen, Sean Parkin, Christopher Sutton, Aron J. Huckaba
Nov 07, 2022
To provide new insights for understanding the influence of B site cations on the structure in chlorometallate materials of the form ABn+Cln+2, we report novel organic-inorganic hybrid metallates (OIHMs) incorporating...
G-quadruplex DNA structures in human stem cells and differentiation.
Katherine G Zyner, Angela Simeone, Sean M Flynn, Colm Doyle, Giovanni Marsico, Santosh Adhikari, Guillem Portella, David Tannahill, Shankar Balasubramanian
Feb 11, 2022
Biomarkers Cell Differentiation Cell Line Cell Lineage DNA DNA Methylation Enhancer Elements Genetic Epigenesis Genetic G-Quadruplexes Gene Expression Histones Human Embryonic Stem Cells Humans Nanog Homeobox Protein Nerve Tissue Proteins Nestin Octamer Transcription Factor-3 PAX6 Transcription Factor Pluripotent Stem Cells Promoter Regions Genetic Protein Processing Post-Translational Receptors Nerve Growth Factor Transcription Factor AP-2
Landscape of G-quadruplex DNA structural regions in breast cancer.
Co-Worker Support and Communities of Practice
Communities of practice foster sharing of knowledge in the organisations. For the creation of such an organisational-level practice community, a motivating environment for the development of such practice communities should be...
Published by: IGI Global Scientific Publishing
Direct Z-Scheme g-C <sub>3</sub> N <sub>4</sub> /FeWO <sub>4</sub> Nanocomposite for Enhanced and Selective Photocatalytic CO <sub>2</sub> Reduction under Visible Light
Reshma Bhosale, Srashti Jain, Chathakudath Prabhakaran Vinod, Santosh Kumar, Satishchandra Ogale
Feb 13, 2019
Photocatalytic reduction of CO 2 to renewable solar fuels is considered to be a promising strategy to simultaneously solve both global warming and energy crises. However, development of a superior photocatalytic...
Chaotic Whale Crow Optimization Algorithm for Secure Routing in the IoT Environment
This paper solves the internet of things (IoT) security issues by introducing a chaotic whale crow (CWC) optimization, which is the integration of chaotic whale optimization algorithm (CWOA) in crow search algorithm (CSA). The...
Published by: IGI Global Scientific Publishing
Enhancing the Readiness for Change Role of Intentional Behaviour, Planfulness, and Learning Through Experimentation
In the prevalent VUCA (volatile-uncertain-complex-ambiguous) environment, the readiness for change has become an antidote to survive and thrive. Drawing on change readiness theory, the present study investigates the hypothesised...
Published by: IGI Global Scientific Publishing
N-doped C dot/CoAl-layered double hydroxide/g-C3N4 hybrid composites for efficient and selective solar-driven conversion of CO2 into CH4
Converting CO 2 into value-added fuel by utilizing abundant solar energy could in principle minimize fossil fuel consumption and anthropogenic CO 2 emissions. However, developing catalytic systems with...
Automated Classification of Sleep Stages Using Single-Channel EEG
The main contribution of this paper is to present a novel approach for classifying the sleep stages based on optimal feature selection with ensemble learning stacking model using single-channel EEG signals.To find the suitable...
Published by: IGI Global Scientific Publishing
Performance Enhancement of the Unbalanced Text Classification Problem Through a Modified Chi Square-Based Feature Selection Technique
This paper proposes a modified chi square-based feature selection algorithm in conjunction with a random vector functional link network-based text classifier for improving the classification performance of multi-labeled text...
Published by: IGI Global Scientific Publishing
Melanoma Detection From Lesion Images Using Optimized Features Selected by Metaheuristic Algorithms
This paper deals with a simple but efficient method for detection of deadly malignant melanoma with optimized hand-crafted feature sets selected by three alternative metaheuristic algorithms, namely Particle Swarm Optimization...
Published by: IGI Global Scientific Publishing
Extreme Min – Cut Max – Flow Algorithm
In this article, the authors propose a maximum flow algorithm based on flow matrix. The algorithm only requires the effort to reduce the capacity of the underutilized arcs to that of the respective flow. The optimality of the...
Published by: IGI Global Scientific Publishing
Photocatalytic Activation and Reduction of CO2 to CH4 over Single Phase Nano Cu3SnS4:
Neha Sharma, Tilak Das, Santosh Kumar, Reshma Bhosale, Mubul Kabir, Satishchandra Ogale
Aug 26, 2019
In view of their ability to absorb visible light and their high surface catalytic activity, metal sulfides are rapidly emerging as promising candidates for CO 2 photoreduction, scoring over the traditional...
Prediction of Environmental Pollution Using Hybrid PSO-K-Means Approach
Air pollution is increasing day by day, decreasing the world economy, degrading the quality of life, and resulting in a major productivity loss. At present, this is one of the most critical problems. It has a significant impact...
Published by: IGI Global Scientific Publishing
Competing chemical and hydrodynamic interactions in autophoretic colloidal suspensions.
At the surfaces of autophoretic colloids, slip velocities arise from local chemical gradients that are many-body functions of particle configuration and activity. For rapid chemical diffusion, coupled with slip-induced...
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