Single cell transcriptomics technologies have vast potential in advancing our understanding of biology and disease. Here, Sarah Aldridge and Sarah Teichmann review the last decade of technological advancements in single-cell...
Wordsworth's poem ‘Yarrow Unvisited’ suggests that it is better not to go somewhere than to go and risk being disappointed. Responding to this idea in the poem ‘Askam Unvisited’, the twentieth-century Cumbrian poet Norman...
Celebrity politician Sarah Palin diffused climate denialism, while advocating a version of social and political conservatism. This article scrutinises her rhetoric and argues that she crafted and performed a brand or ethos that...
As there is usually considerable overlap in the renal venous drainage, it is often possible to ligate supernumerary transplant renal veins in order to simplify the implantation procedure. Nonetheless, decisions about whether to...
We study a free boundary problem for a parabolic partial differential equation in which the solution is coupled to the moving boundary through an integral constraint. The problem arises as the hydrodynamic limit of an...
Celebrity politician Sarah Palin diffused climate denialism, while advocating a version of social and political conservatism. This article scrutinises her rhetoric and argues that she crafted and performed a brand or ethos that...
Kidney normothermic machine perfusion (NMP) has historically used a 95% O2-5% CO2 gas mixture. Using a porcine model of organ retrieval, NMP, and reperfusion, we tested the hypothesis that reducing perfusate oxygenation ( PpO2 )...
BACKGROUND: Kidney transplantation is the treatment of choice for patients with end-stage kidney disease. In a previous review we concluded that the routine use of ureteric stents in kidney transplantation reduces the incidence...
We study a free boundary problem for a parabolic partial differential equation in which the solution is coupled to the moving boundary through an integral constraint. The problem arises as the hydrodynamic limit of an...
BACKGROUND: Ex vivo perfusion (EVP) is a novel method of preservation. However, optimal perfusion conditions remain undetermined. Reducing the temperature of the perfusate to subnormothermia may be beneficial during EVP and...
Normothermic regional perfusion (NRP) and normothermic machine perfusion (NMP) have both been used in the procurement and conditioning of abdominal organs from donation after circulatory death donors with reported improved...
Enhanced recovery after surgery (ERAS) reduces complications and shortens hospital stay without increasing readmission or mortality. However, its role in living donor nephrectomy (LDN) has not yet been defined. Medline, Embase...
Renal ischemia-reperfusion injury (IRI) is a significant clinical challenge faced by clinicians perioperatively in kidney transplantation. Recent work has demonstrated the key importance of transmembrane receptors in the injured...
Students Find a New Way to Connect Democrats Club Active in Upcoming Elections Ursinus and USGA: Who We Are The 9/11 Investigation: Rice vs. Clarke Opinions: Unhappy "Happy Hour"; UC Chess Tournament; Dine Like the Irish at...
Background and objectives: Kidneys from donation after circulatory death (DCD) are more likely to be declined for transplantation compared with kidneys from donation after brain death (DBD). The aim of this study was to evaluate...