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Culture creation and change
This review presents comprehensive analyses of extant research on culture creation and change. We use the framework of culture creation and change (Kim & Toh, 2019), which consists of three unique perspectives, to understand...
Zebrafish neuromesodermal progenitors undergo a critical state transition in vivo.
The transition state model of cell differentiation proposes that a transient window of gene expression stochasticity precedes entry into a differentiated state. Here, we assess this theoretical model in zebrafish neuromesodermal...
SGBS cells as a model of human adipocyte browning
Chia Rou Yeo, Madhur Agrawal, Shawn Hoon, Asim Shabbir, Manu Kunaal Shrivastava, Shiqi Huang, Chin Meng Khoo, Vanna Chhay, M Shabeer Yassin, E Shyong Tai, Antonio Vidal-Puig, Sue-Anne Toh
Oct 09, 2020
The Simpson Golabi Behmel Syndrome (SGBS) pre-adipocyte cell strain is widely considered to be a representative in vitro model of human white pre-adipocytes. A recent study suggested that SGBS adipocytes exhibit an unexpected...
Do Materialistic Consumers Buy More During the COVID-19 Pandemic?
This study investigates the mediated moderating relationship of self-concept clarity, materialism, and social consumption motivation in the context of Covid-19 pandemic based on the terror management theory. The findings suggest...
Published by: IGI Global Scientific Publishing
A Perspective on Cell Therapy and Cancer Vaccine in Biliary Tract Cancers (BTCs).
Shuting Han, Suat Ying Lee, Who-Whong Wang, Yu Bin Tan, Rachel Hui Zhen Sim, Rachael Cheong, Cherlyn Tan, Richard Hopkins, John Connolly, Wai Ho Shuen, Han Chong Toh
Nov 19, 2020
Biliary tract cancer (BTC) is a rare, but aggressive, disease that comprises of gallbladder carcinoma, intrahepatic cholangiocarcinoma and extrahepatic cholangiocarcinoma, with heterogeneous molecular profiles. Advanced disease...
Association of triglyceride-glucose index with clinical outcomes in patients with acute ischemic stroke receiving intravenous thrombolysis.
Emma MS Toh, Amanda YL Lim, Chua Ming, Leonard LL Yeo, Ching-Hui Sia, Bryce WQ Tan, Aloysius ST Leow, Jamie SY Ho, Bernard PL Chan, Vijay Kumar Sharma, Benjamin YQ Tan
Jan 31, 2022
Intravenous tissue plasminogen activator (tPA) remains the cornerstone of recanalization therapy for acute ischemic stroke (AIS), albeit with varying degrees of response. The triglyceride-glucose (TyG) index is a novel marker of...
Genes Involved in Oxidative Stress Pathways Are Differentially Expressed in Circulating Mononuclear Cells Derived From Obese Insulin-Resistant and Lean Insulin-Sensitive Individuals Following a Single Mixed-Meal Challenge.
Sonia Baig, Ehsan Parvaresh Rizi, Chelsea Chia, Muhammad Shabeer, Nweni Aung, Tze Ping Loh, Faidon Magkos, Antonio Vidal-Puig, Raymond CS Seet, Chin Meng Khoo, Sue-Anne Toh
Oct 09, 2020
Background: Oxidative stress induced by nutritional overload has been linked to the pathogenesis of insulin resistance, which is associated with metabolic syndrome, obesity, type 2 diabetes and diabetic vascular complications....
Heredity of type 2 diabetes confers increased susceptibility to oxidative stress and inflammation.
Sonia Baig, Muhammad Shabeer, Ehsan Parvaresh Rizi, Madhur Agarwal, Michelle H Lee, Delicia Shu Qin Ooi, Chelsea Chia, Nweni Aung, Geelyn Ng, Yvonne Teo, Vanna Chhay, Faidon Magkos, Antonio Vidal-Puig, Raymond CS Seet, Sue-Anne Toh
Oct 08, 2020
INTRODUCTION AND OBJECTIVE: Heredity of type 2 diabetes mellitus (T2DM) is associated with greater risk for developing T2DM. Thus, individuals who have a first-degree relative with T2DM (FDRT) provide a natural model to study...
Heredity of type 2 diabetes confers increased susceptibility to oxidative stress and inflammation.
Sonia Baig, Muhammad Shabeer, Ehsan Parvaresh Rizi, Madhur Agarwal, Michelle H Lee, Delicia Shu Qin Ooi, Chelsea Chia, Nweni Aung, Geelyn Ng, Yvonne Teo, Vanna Chhay, Faidon Magkos, Antonio Vidal-Puig, Raymond C S Seet, Sue-Anne Toh
Mar 14, 2020
INTRODUCTION AND OBJECTIVE:Heredity of type 2 diabetes mellitus (T2DM) is associated with greater risk for developing T2DM. Thus, individuals who have a first-degree relative with T2DM (FDRT) provide a natural model to study...
Oxidative Stress Adipocytes Inflammation mononuclear cells myotubes family history of type 2 diabetes
Published by: BMJ open diabetes research & care
Phenotype description and response to thrombopoietin receptor agonist in DIAPH1-related disorder.
Sarah K Westbury, Kate Downes, Claire Burney, Maria L Lozano, Samya G Obaji, Cheng Hock Toh, Teresa Sevivas, Neil V Morgan, Wendy N Erber, Carly Kempster, Samantha F Moore, Chantal Thys, Sofia Papadia, Willem H Ouwehand, NIHR BioResource–Rare Diseases, Michael A Laffan, Keith Gomez, Kathleen Freson, Jose Rivera, Andrew D Mumford
Nov 22, 2018
DIAPH1-related disorder has a bilineage hematological phenotype of macrothrombocytopenia and neutropenia associated with hearing loss. Eltrombopag increased proplatelet formation from cultured DIAPH1-related disorder...
Heredity of type 2 diabetes confers increased susceptibility to oxidative stress and inflammation
Sonia Baig, Muhammad Shabeer, Ehsan Parvaresh Rizi, Madhur Agarwal, Michelle H Lee, Delicia Shu Qin Ooi, Chelsea Chia, Nweni Aung, Geelyn Ng, Yvonne Teo, Vanna Chhay, Faidon Magkos, Antonio Vidal-Puig, Raymond C S Seet, Sue-Anne Toh
Feb 10, 2020
Introduction and objective: Heredity of type 2 diabetes mellitus (T2DM) is associated with greater risk for developing T2DM. Thus, individuals who have a first-degree relative with T2DM (FDRT) provide a natural model to study...
Correlates of Hallucinatory Experiences in the General Population
Peter Moseley, André Aleman, Paul Allen, Vaughan Bell, Josef Bless, Catherine Bortolon, Matteo Cella, Jane Garrison, Kenneth Hugdahl, Eva Kozáková, Frank Larøi, Jamie Moffatt, Nicolas Say, David Smailes, Mimi Suzuki, Wei Lin Toh, Todd Woodward, Yuliya Zaytseva, Susan Rossell, Charles Fernyhough
Jul 28, 2021
Hallucinatory experiences can occur in both clinical and nonclinical groups. However, in previous studies of the general population, investigations of the cognitive mechanisms underlying hallucinatory experiences have yielded...
A Deletion in the Canine POMC Gene Is Associated with Weight and Appetite in Obesity-Prone Labrador Retriever Dogs.
Eleanor Raffan, Rowena J Dennis, Conor J O'Donovan, Julia M Becker, Robert A Scott, Stephen P Smith, David J Withers, Claire J Wood, Elena Conci, Dylan N Clements, Kim M Summers, Alexander J German, Cathryn S Mellersh, Maja L Arendt, Valentine P Iyemere, Elaine Withers, Josefin Söder, Sara Wernersson, Göran Andersson, Kerstin Lindblad-Toh, Giles SH Yeo, Stephen O'Rahilly
Apr 12, 2016
Does It Par-<i>tickle</i>?
Mid-air haptic feedback technology produces tactile sensations that are felt without the need for physical interactions. However, mid-air haptic experiences need to be congruent with visual cues to reflect user expectations. To...
Haptic interfaces Mid-air haptic Rough surfaces standards Surface roughness Surface texture Three-dimensional displays Visualization PARTICLES ultrasound haptics Visualization /dk/atira/pure/subjectarea/asjc/1700/1709 name=Human-Computer Interaction /dk/atira/pure/subjectarea/asjc/1700/1706 name=Computer Science Applications
Does It Par-<i>tickle</i>?
Mid-air haptic feedback technology produces tactile sensations that are felt without the need for physical interactions. However, mid-air haptic experiences need to be congruent with visual cues to reflect user expectations. To...
Haptic interfaces Mid-air haptic Rough surfaces standards Surface roughness Surface texture Three-dimensional displays Visualization PARTICLES ultrasound haptics Visualization /dk/atira/pure/subjectarea/asjc/1700/1709 name=Human-Computer Interaction /dk/atira/pure/subjectarea/asjc/1700/1706 name=Computer Science Applications
Why sequence all eukaryotes?
Mark Blaxter, John M Archibald, Anna K Childers, Jonathan A Coddington, Keith A Crandall, Federica Di Palma, Richard Durbin, Scott V Edwards, Jennifer AM Graves, Kevin J Hackett, Neil Hall, Erich D Jarvis, Rebecca N Johnson, Elinor K Karlsson, W John Kress, Shigehiro Kuraku, Mara Kn Lawniczak, Kerstin Lindblad-Toh, Jose V Lopez, Nancy A Moran, Gene E Robinson, Oliver A Ryder, Beth Shapiro, Pamela S Soltis, Tandy Warnow, Guojie Zhang, Harris A Lewin
Feb 19, 2022
Life on Earth has evolved from initial simplicity to the astounding complexity we experience today. Bacteria and archaea have largely excelled in metabolic diversification, but eukaryotes additionally display abundant...
Standards Recommendations for the Earth BioGenome Project
Mara Lawniczak, Richard Durbin, Paul Flicek, Kerstin Lindlad-Toh, Xiaofeng Wei, John Archibald, William Baker, Katherine Belov, Mark Blaxter, Tomas Marques Bonet, Anna Childers, Jonathan Coddington, Keith Crandall, Andrew Crarwford, Robert Davey, Federica Di Palma, Qi Fang, Wilfried Haerty, Neil Hall, Katharina Hoff, Kerstin Howe, Erich Jarvis, Warren Johnson, Rebecca Johnson, Paul Kersey, Xin Liu, Jose Victor Lopez, Eugene Myers, Olga Pettersson, Adam Phillippy, Monica Poelchau, Kim Pruitt, Arang Rhie, Juan Carlos Castilla Rubio, Sunil Kumar Sahu, Nicholas Salmon, Pamela Solitis, David Swarbreck, Francoise Thibaud-Nissen, Sibo Wang, Jill Wegrzyn, Guojie Zhang, He Zhang, Harris Lewin, Stephen Richards
Feb 19, 2022
The Earth BioGenome Project 2020
Harris A Lewin, Stephen Richards, Erez Lieberman Aiden, Miguel L Allende, John M Archibald, Miklós Bálint, Katharine B Barker, Bridget Baumgartner, Katherine Belov, Giorgio Bertorelle, Mark L Blaxter, Jing Cai, Nicolette D Caperello, Keith Carlson, Juan Carlos Castilla-Rubio, Shu-Miaw Chaw, Lei Chen, Anna K Childers, Jonathan A Coddington, Dalia A Conde, Montserrat Corominas, Keith A Crandall, Andrew J Crawford, Federica DiPalma, Richard Durbin, ThankGod E Ebenezer, Scott V Edwards, Olivier Fedrigo, Paul Flicek, Giulio Formenti, Richard A Gibbs, M Thomas P Gilbert, Melissa M Goldstein, Jennifer Marshall Graves, Henry T Greely, Igor V Grigoriev, Kevin J Hackett, Neil Hall, David Haussler, Kristofer M Helgen, Carolyn J Hogg, Sachiko Isobe, Kjetill Sigurd Jakobsen, Axel Janke, Erich D Jarvis, Warren E Johnson, Steven JM Jones, Elinor K Karlsson, Paul J Kersey, Jin-Hyoung Kim, W John Kress, Shigehiro Kuraku, Mara Kn Lawniczak, James H Leebens-Mack, Xueyan Li, Kerstin Lindblad-Toh, Xin Liu, Jose V Lopez, Tomas Marques-Bonet, Sophie Mazard, Jonna AK Mazet, Camila J Mazzoni, Eugene W Myers, Rachel J O'Neill, Sadye Paez, Hyun Park, Gene E Robinson, Cristina Roquet, Oliver A Ryder, Jamal SM Sabir, H Bradley Shaffer, Timothy M Shank, Jacob S Sherkow, Pamela S Soltis, Boping Tang, Leho Tedersoo, Marcela Uliano-Silva, Kun Wang, Xiaofeng Wei, Regina Wetzer, Julia L Wilson, Xun Xu, Huanming Yang, Anne D Yoder, Guojie Zhang
Feb 19, 2022
Phenotypic Characterization of
<i>EIF2AK4</i>
Mutation Carriers in a Large Cohort of Patients Diagnosed Clinically With Pulmonary Arterial Hypertension
Background:
Pulmonary arterial hypertension (PAH) is a rare disease with an emerging genetic basis. Heterozygous mutations in the gene encoding...
Charaka Hadinnapola, Marta Bleda, Matthias Haimel, Nicholas Screaton, Andrew Swift, Peter Dorfmüller, Stephen D Preston, Mark Southwood, Jules Hernandez-Sanchez, Jennifer Martin, Carmen Treacy, Katherine Yates, Harm Bogaard, Colin Church, Gerry Coghlan, Robin Condliffe, Paul A Corris, Simon Gibbs, Barbara Girerd, Simon Holden, Marc Humbert, David G Kiely, Allan Lawrie, Rajiv Machado, Robert MacKenzie Ross, Shahin Moledina, David Montani, Michael Newnham, Andrew Peacock, Joanna Pepke-Zaba, Paula Rayner-Matthews, Olga Shamardina, Florent Soubrier, Laura Southgate, Jay Suntharalingam, Mark Toshner, Richard Trembath, Anton Vonk Noordegraaf, Martin R Wilkins, Stephen J Wort, John Wharton, Stefan Gräf, Nicholas W Morrell, Timothy Aitman, David Bennett, Mark Caulfield, Patrick Chinnery, Daniel Gale, Ania Koziell, Taco W Kuijpers, Michael A Laffan, Eamonn Maher, Hugh S Markus, Willem H Ouwehand, David Perry, F Lucy Raymond, Irene Roberts, Kenneth Smith, Adrian Thrasher, Hugh Watkins, Catherine Williamson, Geoffrey Woods, Sofie Ashford, John R Bradley, Debra Fletcher, Tracey Hammerton, Roger James, Nathalie Kingston, Willem H Ouwehand, Christopher J Penkett, F Lucy Raymond, Kathleen Stirrups, Marijke Veltman, Tim Young, Sofie Ashford, Matthew Brown, Naomi Clements-Brod, John Davis, Eleanor Dewhurst, Marie Erwood, Amy Frary, Rachel Linger, Sofia Papadia, Karola Rehnstrom, Hannah Stark, David Allsup, Steve Austin, Tamam Bakchoul, Tadbir K Bariana, Paula Bolton-Maggs, Elizabeth Chalmers, Peter Collins, Wendy N Erber, Tamara Everington, Remi Favier, Kathleen Freson, Bruce Furie, Michael Gattens, Keith Gomez, Daniel Greene, Andreas Greinacher, Daniel Hart, Johan WM Heemskerk, Yvonne Henskens, Rashid Kazmi, David Keeling, Anne M Kelly, Michael A Laffan, Michele P Lambert, Claire Lentaigne, Ri Liesner, Sarah Mangles, Mary Mathias, Carolyn M Millar, Andrew Mumford, Paquita Nurden, Willem H Ouwehand, Sofia Papadia, Jeanette Payne, John Pasi, David J Perry, Kathelijne Peerlinck, Michael Richards, Matthew Rondina, Catherine Roughley, Sol Schulman, Harald Schulze, Marie Scully, Suthesh Sivapalaratnam, R Campbell Tait, Kate Talks, Jecko Thachil, Ernest Turro, Cheng-Hock Toh, Chris van Geet, Minka De Vries, Timothy Q Warner, Sarah Westbury, Abigail Furnell, Rutendo Mapeta, Ilenia Simeoni, Simon Staines, Jonathan Stephens, Kathleen Stirrups, Deborah Whitehorn, Christopher Watt, Antony Attwood, Louise Daugherty, Sri VV Deevi, Csaba Halmagyi, Fengyuan Hu, Roger James, Vera Matser, Stuart Meacham, Karyn Megy, Christopher J Penkett, Kathleen Stirrups, Catherine Titterton, Salih Tuna, Ping Yu, Julie von Ziegenweldt, William Astle, Keren Carss, Daniel Greene, Hana Lango-Allen, Ernest Turro, William Astle, Daniel Greene, Sylvia Richardson, Ernest Turro, Paul Calleja, Stuart Rankin, Wojciech Turek, Christine Bryson, Julie Anderson, Debra Fletcher, Coleen McJannet, Sophie Stock, Tim Young, Evangeline Wassmer, Aman Sohal, Saikat Santra, Julie Vogt, Manali Chitre, Deepa Krishnakumar, Gautum Ambegaonkar, Anna Maw, Ruth Armstrong, Soo-Mi Park, Sarju Mehta, Joan Paterson, Jenny Carmichael, Louise Allen, Anke Hensiek, Helen Firth, Penelope Stein, Patrick Deegan, Rainer Doffinger, Alasdair Parker, Maria Bitner-Glindzicz, Richard Scott, Jane Hurst, Elisabeth Rosser, Melissa Lees, Emma Clement, Robert Henderson, Dorothy Thompson, Alice Gardham, Paul Gissen, Dragana Josifova, Ellen Thomas, Chris Patch, Charu Deshpande, Frances Flinter, Muriel Holder, Natalie Canham, Emma Wakeling, Susan Holder, Neeti Ghali, Angie Brady, Virginia Clowes, Robert MacLaren, Andrew Webster, Anthony Moore, Gavin Arno, Michel Michaelides, Julia Rankin, Manju Kurian, Elaine Murphy, Keren Carss, Alba Sanchis-Juan, Marie Erwood, Eleanor Dewhurst, Detelina Grozeva, F Lucy Raymond, Evan Reid, Geoff Woods, Marc Tischkowitz, Richard Sandford, Sonia Ali, Amanda Creaser-Myers, Victoria Cookson, Rosa DaCosta, Natalie Dormand, Pavandeep K Ghataorhe, Alan Greenhalgh, Anna Huis in’t Veld, Fiona Kennedy, Rob Mackenzie Ross, Larahmie Masati, Sharon Meehan, Shokri Othman, Val Pollock, Gary Polwarth, Christopher J Rhodes, Kevin Rue-Albrecht, Gwen Schotte, Debbie Shipley, Yvonne Tan, Ivy Wanjiku, John Wort, Kenneth Smith, Taco Kuijpers, Adrian Thrasher, James Thaventhiran, Matthew Brown, Hana Lango Allen, Ilenia Simeoni, Emily Staples, Crina Samarghitean, Hana Alachkar, Richard Antrobus, Gururaj Arumugakani, Chiara Bacchelli, Helen Baxendale, Claire Bethune, Shahnaz Bibi, Claire Booth, Michael Browning, Siobhan Burns, Anita Chandra, Nichola Cooper, Sophie Davies, Lisa Devlin, Rainer Doffinger, Elizabeth Drewe, David Edgar, William Egner, Rohit Ghurye, Kimberley Gilmour, Sarah Goddard, Pavel Gordins, Sofia Grigoriadou, Scott Hackett, Rosie Hague, Grant Hayman, Archana Herwadkar, Aarnoud Huissoon, Stephen Jolles, Peter Kelleher, Dinakantha Kumararatne, Sara Lear, Hilary Longhurst, Lorena Lorenzo, Jesmeen Maimaris, Ania Manson, Elizabeth McDermott, Sai Murng, Sergey Nejentsev, Sadia Noorani, Eric Oksenhendler, Mark Ponsford, Waseem Qasim, Isabella Quinti, Alex Richter, Ravishankar Sargur, Sinisa Savic, Suranjith Seneviratne, Carrock Sewell, Hans Stauss, Moira Thomas, Steve Welch, Lisa Willcocks, Nigel Yeatman, Patrick Yong
Jun 20, 2018