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Cut-off Value of Random Blood Glucose among Asian Indians for Preliminary Screening of Persons with Prediabetes and Undetected Type 2 Diabetes Defined by the Glycosylated Haemoglobin Criteria.
Priscilla Susairaj, Chamukuttan Snehalatha, Arun Raghavan, Arun Nanditha, Ramachandran Vinitha, Krishnamoorthy Satheesh, Desmond G Johnston, Nicholas J Wareham, Ambady Ramachandran
Apr 05, 2020
AIM: The increased morbidity and mortality due to type 2 diabetes can be partly due to its delayed diagnosis. In developing countries, the cost and unavailability of conventional screening methods can be a setback. Use of random...
Hypoxia-induced SETX links replication stress with the unfolded protein response.
Shaliny Ramachandran, Tiffany S Ma, Jon Griffin, Natalie Ng, Iosifina P Foskolou, Ming-Shih Hwang, Pedro Victori, Wei-Chen Cheng, Francesca M Buffa, Katarzyna B Leszczynska, Sherif F El-Khamisy, Natalia Gromak, Ester M Hammond
Aug 20, 2021
Tumour hypoxia is associated with poor patient prognosis and therapy resistance. A unique transcriptional response is initiated by hypoxia which includes the rapid activation of numerous transcription factors in a background of...
Activating Transcription Factor 4 Cell Death Cell Hypoxia Cell Line Tumor Cell Survival Chromatin Immunoprecipitation DNA Damage DNA Helicases Gene Expression Regulation Humans Multifunctional Enzymes Nucleic Acid Synthesis Inhibitors Oxygen R-Loop Structures RNA Helicases RNA-seq Unfolded Protein Response Up-Regulation Zinostatin eIF-2 Kinase
A pragmatic and scalable strategy using mobile technology to promote sustained lifestyle changes to prevent type 2 diabetes in India and the UK
Arun Nanditha, Hazel Thomson, Priscilla Susairaj, Weerachai Srivanichakorn, Nick Oliver, Ian F. Godsland, Azeem Majeed, Ara Darzi, Krishnamoorthy Satheesh, Mary Simon, Arun Raghavan, Ramachandran Vinitha, Chamukuttan Snehalatha, Kate Westgate, Soren Brage, Stephen J. Sharp, Nicholas J. Wareham, Desmond G. Johnston, Ambady Ramachandran
Jun 06, 2020
Abstract: Aims/hypothesis: This randomised controlled trial was performed in India and the UK in people with prediabetes to study whether mobile phone short message service (SMS) text messages can be used to motivate and educate...
A pragmatic and scalable strategy using mobile technology to promote sustained lifestyle changes to prevent type 2 diabetes in India and the UK
Arun Nanditha, Hazel Thomson, Priscilla Susairaj, Weerachai Srivanichakorn, Nick Oliver, Ian F Godsland, Azeem Majeed, Ara Darzi, Krishnamoorthy Satheesh, Mary Simon, Arun Raghavan, Ramachandran Vinitha, Chamukuttan Snehalatha, Kate Westgate, Soren Brage, Stephen J Sharp, Nicholas J Wareham, Desmond G Johnston, Ambady Ramachandran
Nov 05, 2019
Behavioural change Diabetes prevention Glycosylated haemoglobin A1c Lifestyle modification Mobile technology Prediabetes screening Short message service Adult Aged Blood Glucose Cell Phone Diabetes mellitus Type 2 Female Glycated Hemoglobin Humans Hyperglycemia india Life Style Male Middle Aged Monitoring Physiologic Prediabetic State PREVENTIVE MEDICINE Program Evaluation Risk Reduction Behavior Sample Size Telemedicine Text Messaging United Kingdom
A pragmatic and scalable strategy using mobile technology to promote sustained lifestyle changes to prevent type 2 diabetes in India and the UK
Arun Nanditha, Hazel Thomson, Priscilla Susairaj, Weerachai Srivanichakorn, Nick Oliver, Ian F. Godsland, Azeem Majeed, Ara Darzi, Krishnamoorthy Satheesh, Mary Simon, Arun Raghavan, Ramachandran Vinitha, Chamukuttan Snehalatha, Kate Westgate, Soren Brage, Stephen J. Sharp, Nicholas J. Wareham, Desmond G. Johnston, Ambady Ramachandran
Jan 08, 2021
Abstract: Aims/hypothesis: This randomised controlled trial was performed in India and the UK in people with prediabetes to study whether mobile phone short message service (SMS) text messages can be used to motivate and educate...
Nutritional basis of type 2 diabetes remission.
Roy Taylor and colleagues explain how type 2 diabetes can be reversed by weight loss and avoidance of weight regain
"Fake it till You Make it"! Contaminating Rubber Hands ("Multisensory Stimulation Therapy") to Treat Obsessive-Compulsive Disorder.
Baland Jalal, Richard J McNally, Jason A Elias, Sriramya Potluri, Vilayanur S Ramachandran
Jan 23, 2020
Obsessive-compulsive disorder (OCD) is a deeply enigmatic psychiatric condition associated with immense suffering worldwide. Efficacious therapies for OCD, like exposure and response prevention (ERP), are sometimes poorly...
Inkjet Printing Infiltration of the Doped Ceria Interlayer in Commercial Anode-Supported SOFCs.
Rumen Tomov, Thomas B Mitchel-Williams, Eleonora Venezia, Michal Kawalec, Mariusz Krauz, Ramachandran Kumar, Bartek Glowacki
Nov 22, 2021
Single-step inkjet printing infiltration with doped ceria Ce0.9Ye0.1O1.95 (YDC) and cobalt oxide (CoxOy) precursor inks was performed in order to modify the properties of the doped ceria interlayer in commercial (50 × 50 × 0.5...
Novel Smartphone Interventions Improve Cognitive Flexibility and Obsessive-Compulsive Disorder Symptoms in Individuals with Contamination Fears.
Baland Jalal, Annette Brühl, Claire O'Callaghan, Thomas Piercy, Rudolf N Cardinal, Vilayanur S Ramachandran, Barbara J Sahakian
Nov 02, 2018
One type of obsessive-compulsive disorder (OCD) is characterized by contamination fears and compulsive cleansing. Few effective treatments are available for this debilitating condition. Compulsive symptoms, such as excessive...
H2O2 rejuvenation-mediated synthesis of stable mixed-morphology Ag3PO4 photocatalysts.
Ag3PO4 photocatalyst has attracted interest of the scientific community in recent times due to its reported high efficiency for water oxidation and dye degradation. However, Ag3PO4 photo-corrodes if electron accepter such as...
Super-enhancer associated core regulatory circuits mediate susceptibility to retinoic acid in neuroblastoma cells
Roshna Lawrence Gomez, Laura M Woods, Revathy Ramachandran, Ahmad N Abou Tayoun, Anna Philpott, Fahad R Ali
Sep 20, 2022
Advancing the Use of High-Performance Graphene-Based Multimodal Polymer Nanocomposite at Scale.
Ibrahim A Ahmad, Krzysztof KK Koziol, Suleyman Deveci, Hyun-Kyung Kim, Ramachandran Vasant Kumar
Feb 18, 2019
The production of an innovative, high-performance graphene-based polymer nanocomposite using cost-effective techniques was pursued in this study. Well-dispersed and uniformly distributed graphene platelets within a polymer...
Predicting Academic Performance of Immigrant Students Using XGBoost Regressor
The education sector has been effectively dealing with the prediction of academic performance of the Immigrant students since the research associated with this domain proves beneficial enough for those countries where the...
Published by: IGI Global Scientific Publishing
An evaluation of the Johanson model for roller compaction process development for a high dose API
Kevin M. Moroney, Patrick Cronin, Opeyemi A. Adeleye, Barbara E. Schaller, Matthew A. Howard, Bernardo Castro-Dominguez, Rohit Ramachandran, Gavin M. Walker
Apr 15, 2020
Roller compaction (RC) is a dry granulation technique applied to improve the flow and compressibility of drug formulations. RC implementation for high drug load formulations can be challenging due to flow issues and a high...
Utilization of Transfer Learning Model in Detecting COVID-19 Cases From Chest X-Ray Images
L. Anbarasi, Malathy Jawahar, Prassanna Jayachandran, Manikandan Ramachandran, Fadi Al-Turjman
Jul 01, 2021
Diagnosis of COVID-19 pneumonia using patients’ chest X-Ray images is new but yet important task in the field of medicine. Researchers from different parts of the globe have developed many deep learning models to classify...
Published by: IGI Global Scientific Publishing
Inkjet Printing Infiltration of the Doped Ceria Interlayer in Commercial Anode-Supported SOFCs.
Rumen I Tomov, Thomas B Mitchel-Williams, Eleonora Venezia, Michal Kawalec, Mariusz Krauz, Ramachandran Vasant Kumar, Bartek A Glowacki
Jan 07, 2022
Single-step inkjet printing infiltration with doped ceria Ce0.9Ye0.1O1.95 (YDC) and cobalt oxide (CoxOy) precursor inks was performed in order to modify the properties of the doped ceria interlayer in commercial (50 × 50 × 0.5...
An evaluation of the Johanson model for roller compaction process development for a high dose API
Kevin M. Moroney, Patrick Cronin, Opeyemi A. Adeleye, Barbara E. Schaller, Matthew A. Howard, Bernardo Castro-Dominguez, Rohit Ramachandran, Gavin M. Walker
Apr 15, 2020
Roller compaction (RC) is a dry granulation technique applied to improve the flow and compressibility of drug formulations. RC implementation for high drug load formulations can be challenging due to flow issues and a high...
Testosterone Therapy in Adult-Onset Testosterone Deficiency
N Lorde, A Maarouf, RC Strange, CS König, G Hackett, A Haider, KS Haider, P Desnerck, F Saad, S Ramachandran
Oct 04, 2021
Objective: Hematocrit (HCT)/hemoglobin (Hb) ratio in (%/g/dL) is around 3, with high fidelity between measured
and derived Hb (applying the conversion using HCT) in various pathologies. We examined changes in
HCT and Hb values...
Klinefelters Syndrome
RC Strange, CS König, A Puttanna, A Rao, G Hackett, A Haider, KS Haider, P Desnerck, F Saad, S Ramachandran
Jul 29, 2021
Background: Klinefelter’s syndrome (KS) is characterized by extra X chromosomes and features of primary hypogonadism including osteopenia and osteoporosis. Testosterone therapy (TTh) is widely used to treat men with KS and low...
Pathogenic ACVR1R206H activation by Activin A-induced receptor clustering and autophosphorylation.
Anassuya Ramachandran, Merima Mehić, Laabiah Wasim, Dessislava Malinova, Ilaria Gori, Beata K Blaszczyk, Diana M Carvalho, Eileen M Shore, Chris Jones, Marko Hyvönen, Pavel Tolar, Caroline S Hill
May 20, 2021
A plasma metabolite score of three eicosanoids predicts incident type 2 diabetes
Karolina Tuomisto, Joonatan Palmu, Tao Long, Jeramie D Watrous, Kysha Mercader, Kim A Lagerborg, Allen Andres, Marko Salmi, Sirpa Jalkanen, Ramachandran S Vasan, Michael Inouye, Aki S Havulinna, Jaakko Tuomilehto, Pekka Jousilahti, Teemu J Niiranen, Susan Cheng, Mohit Jain, Veikko Salomaa
Apr 05, 2022
INTRODUCTION: Peptide markers of inflammation have been associated with the development of type 2 diabetes. The role of upstream, lipid-derived mediators of inflammation such as eicosanoids, remains less clear. The aim of this...
A plasma metabolite score of three eicosanoids predicts incident type 2 diabetes
Karolina Tuomisto, Joonatan Palmu, Tao Long, Jeramie D Watrous, Kysha Mercader, Kim A Lagerborg, Allen Andres, Marko Salmi, Sirpa Jalkanen, Ramachandran S Vasan, Michael Inouye, Aki S Havulinna, Jaakko Tuomilehto, Pekka Jousilahti, Teemu J Niiranen, Susan Cheng, Mohit Jain, Veikko Salomaa
May 09, 2022
INTRODUCTION: Peptide markers of inflammation have been associated with the development of type 2 diabetes. The role of upstream, lipid-derived mediators of inflammation such as eicosanoids, remains less clear. The aim of this...
Single-Cell Transcriptomics Uncovers Zonation of Function in the Mesenchyme during Liver Fibrosis.
Ross Dobie, John R Wilson-Kanamori, Beth EP Henderson, James R Smith, Kylie P Matchett, Jordan R Portman, Karolina Wallenborg, Simone Picelli, Anna Zagorska, Swetha V Pendem, Thomas E Hudson, Minnie M Wu, Grant R Budas, David G Breckenridge, Ewen M Harrison, Damian J Mole, Stephen J Wigmore, Prakash Ramachandran, Chris P Ponting, Sarah A Teichmann, John C Marioni, Neil C Henderson
Dec 19, 2019
Iterative liver injury results in progressive fibrosis disrupting hepatic architecture, regeneration potential, and liver function. Hepatic stellate cells (HSCs) are a major source of pathological matrix during fibrosis and are...
Joint associations of accelerometer measured physical activity and sedentary time with all-cause mortality
Ulf Ekelund, Jakob Tarp, Morten W Fagerland, Jostein Steene Johannessen, Bjørge H Hansen, Barbara J Jefferis, Peter H Whincup, Keith M Diaz, Steven Hooker, Virginia J Howard, Ariel Chernofsky, Martin G Larson, Nicole Spartano, Ramachandran S Vasan, Ing-Mari Dohrn, Maria Hagströmer, Charlotte Edwardson, Thomas Yates, Eric J Shiroma, Paddy Dempsey, Katrien Wijndaele, Sigmund A Anderssen, I-Min Lee
Nov 16, 2020
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