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CDNA-SNN
Spiking neural networks (SNNs) mimic their biological counterparts more closely than their predecessors and are considered the third generation of artificial neural networks. It has been proven that networks of spiking neurons...
Backpropagation Biological neural networks Class-dependent neuronal activation (CDNA) Firing Membrane Potentials Neurons Nonhomogeneous media Training leaky integrate and fire (LIF) neuronal assembly spiking neural network (SNN) spiking neurons /dk/atira/pure/subjectarea/asjc/1700/1712 name=Software /dk/atira/pure/subjectarea/asjc/1700/1702 name=Artificial Intelligence /dk/atira/pure/subjectarea/asjc/1700/1705 name=Computer Networks and Communications /dk/atira/pure/subjectarea/asjc/1700/1706 name=Computer Science Applications
CDNA-SNN
Spiking neural networks (SNNs) mimic their biological counterparts more closely than their predecessors and are considered the third generation of artificial neural networks. It has been proven that networks of spiking neurons...
Backpropagation Biological neural networks Class-dependent neuronal activation (CDNA) Firing Membrane Potentials Neurons Nonhomogeneous media Training leaky integrate and fire (LIF) neuronal assembly spiking neural network (SNN) spiking neurons /dk/atira/pure/subjectarea/asjc/1700/1712 name=Software /dk/atira/pure/subjectarea/asjc/1700/1702 name=Artificial Intelligence /dk/atira/pure/subjectarea/asjc/1700/1705 name=Computer Networks and Communications /dk/atira/pure/subjectarea/asjc/1700/1706 name=Computer Science Applications
Scoping article
Thomas Hickmann, Frank Biermann, Carole-Anne Sénit, Yixian Sun, Magdalena Bexell, Mitzi Bolton, Basil Bornemann, Jacel Censoro, Aurelie Charles, Rodrigo Correa Ramiro, Dominique Coy, Frederik Dahlmann, Mark Elder, Felicitas Fritzsche, Thiago Gehre Galvão, Jarrod Grainger-Brown, Cristina Inoue, Kristina Jönsson, Montserrat Koloffon Rosas, Kerstin Krellenberg, Enayat Moallemi, Ivonne Lobos Alva, Shirin Malekpour, Dianty Ningrum, Aneliya Paneva, Lena Partzsch, Rob Raven, Eszter Szedlacsek, John Thompson, Melanie van Driel, Jéssica Viani Damasceno, Robert Webb, Sabine Weiland
Jan 24, 2024
A recent meta-analysis on the political impact of the Sustainable Development Goals (SDGs) has shown that these global goals are moving political processes forward only incrementally, with much variation across countries...
Scoping article
Thomas Hickmann, Frank Biermann, Carole-Anne Sénit, Yixian Sun, Magdalena Bexell, Mitzi Bolton, Basil Bornemann, Jacel Censoro, Aurelie Charles, Rodrigo Correa Ramiro, Dominique Coy, Frederik Dahlmann, Mark Elder, Felicitas Fritzsche, Thiago Gehre Galvão, Jarrod Grainger-Brown, Cristina Inoue, Kristina Jönsson, Montserrat Koloffon Rosas, Kerstin Krellenberg, Enayat Moallemi, Ivonne Lobos Alva, Shirin Malekpour, Dianty Ningrum, Aneliya Paneva, Lena Partzsch, Rob Raven, Eszter Szedlacsek, John Thompson, Melanie van Driel, Jéssica Viani Damasceno, Robert Webb, Sabine Weiland
Jan 24, 2024
A recent meta-analysis on the political impact of the Sustainable Development Goals (SDGs) has shown that these global goals are moving political processes forward only incrementally, with much variation across countries...
Neurological and respiratory effects of lung protective ventilation in acute brain injury patients without lung injury
Erta Beqiri, Peter Smielewski, Claude Guérin, Marek Czosnyka, Chiara Robba, Lars Bjertnæs, Shirin K Frisvold
Mar 20, 2023
acute brain injury cerebral autoregulation Intracranial Pressure Lung protective ventilation Positive end-expiratory pressure subarachnoid haemorrhage Transpulmonary pressure Traumatic brain injury Humans Respiratory Rate Carbon Dioxide Prospective Studies Cross-Over Studies Tidal Volume Brain Injuries Lung Injury Brain
Gene Ontology curation of the blood-brain barrier to improve the analysis of Alzheimer's and other neurological diseases.
Shirin CC Saverimuttu, Barbara Kramarz, Milagros Rodríguez-López, Penelope Garmiri, Helen Attrill, Katherine E Thurlow, Marios Makris, Sandra de Miranda Pinheiro, Sandra Orchard, Ruth C Lovering
Jan 06, 2022
Autonomic Nervous System Activity during Refractory Rise in Intracranial Pressure.
Marta Fedriga, Andras Czigler, Nathalie Nasr, Frederick A Zeiler, Soojin Park, Joseph Donnelly, Vasilios Papaioannou, Shirin K Frisvold, Stephan Wolf, Frank Rasulo, Marek Sykora, Peter Smielewski, Marek Czosnyka
Mar 09, 2021
Vaccination with SARS-CoV-2 variants of concern protects mice from challenge with wild-type virus
Fatima Amanat, Shirin Strohmeier, Philip S. Meade, Nicholas Dambrauskas, Barbara Mühlemann, Derek J. Smith, Vladimir Vigdorovich, D. Noah Sather, Lynda Coughlan, Florian Krammer
Jan 28, 2022
Hospital admission and emergency care attendance risk for SARS-CoV-2 delta (B.1.617.2) compared with alpha (B.1.1.7) variants of concern
Katherine A Twohig, Tommy Nyberg, Asad Zaidi, Simon Thelwall, Mary A Sinnathamby, Shirin Aliabadi, Shaun R Seaman, Ross J Harris, Russell Hope, Jamie Lopez-Bernal, Eileen Gallagher, Andre Charlett, Daniela De Angelis, Anne M Presanis, Gavin Dabrera
Oct 01, 2021
Published by: The Lancet. Infectious diseases
Hospital admission and emergency care attendance risk for SARS-CoV-2 delta (B.1.617.2) compared with alpha (B.1.1.7) variants of concern
Katherine A Twohig, Tommy Nyberg, Asad Zaidi, Simon Thelwall, Mary A Sinnathamby, Shirin Aliabadi, Shaun R Seaman, Ross J Harris, Russell Hope, Jamie Lopez-Bernal, Eileen Gallagher, Andre Charlett, Daniela De Angelis, Anne M Presanis, Gavin Dabrera, COVID-19 Genomics UK (COG-UK) Consortium
Oct 06, 2021
Combining rapid antigen testing and syndromic surveillance improves community-based COVID-19 detection in a low-income country.
Fergus J Chadwick, Jessica Clark, Shayan Chowdhury, Tasnuva Chowdhury, David J Pascall, Yacob Haddou, Joanna Andrecka, Mikolaj Kundegorski, Craig Wilkie, Eric Brum, Tahmina Shirin, ASM Alamgir, Mahbubur Rahman, Ahmed Nawsher Alam, Farzana Khan, Ben Swallow, Frances S Mair, Janine Illian, Caroline L Trotter, Davina L Hill, Dirk Husmeier, Jason Matthiopoulos, Katie Hampson, Ayesha Sania
Jun 29, 2022
Diagnostics for COVID-19 detection are limited in many settings. Syndromic surveillance is often the only means to identify cases but lacks specificity. Rapid antigen testing is inexpensive and easy-to-deploy but can lack...
Genomics, social media and mobile phone data enable mapping of SARS-CoV-2 lineages to inform health policy in Bangladesh
Lauren A. Cowley, Mokibul Hassan Afrad, Sadia Isfat Ara Rahman, Md Mahfuz Al Mamun, Taylor Chin, Ayesha Mahmud, Mohammed Ziaur Rahman, Mallick Masum Billah, Manjur Hossain Khan, Sharmin Sultana, Tilovatul Khondaker, Stephen Baker, Nandita Banik, Ahmed Nawsher Alam, Kaiissar Mannoor, Sayera Banu, Anir Chowdhury, Meerjady Sabrina Flora, Nicholas R. Thomson, Caroline O. Buckee, Firdausi Qadri, Tahmina Shirin
Oct 01, 2021
Genomics, social media and mobile phone data enable mapping of SARS-CoV-2 lineages to inform health policy in Bangladesh.
Lauren A Cowley, Mokibul Hassan Afrad, Sadia Isfat Ara Rahman, Md Mahfuz Al Mamun, Taylor Chin, Ayesha Mahmud, Mohammed Ziaur Rahman, Mallick Masum Billah, Manjur Hossain Khan, Sharmin Sultana, Tilovatul Khondaker, Stephen Baker, Nandita Banik, Ahmed Nawsher Alam, Kaiissar Mannoor, Sayera Banu, Anir Chowdhury, Meerjady Sabrina Flora, Nicholas R Thomson, Caroline O Buckee, Firdausi Qadri, Tahmina Shirin
Oct 27, 2021
Genomics, combined with population mobility data, used to map importation and spatial spread of SARS-CoV-2 in high-income countries has enabled the implementation of local control measures. Here, to track the spread of...
Combining rapid antigen testing and syndromic surveillance improves community-based COVID-19 detection in a low-income country.
Fergus J Chadwick, Jessica Clark, Shayan Chowdhury, Tasnuva Chowdhury, David Pascall, Yacob Haddou, Joanna Andrecka, Mikolaj Kundegorski, Craig Wilkie, Eric Brum, Tahmina Shirin, ASM Alamgir, Mahbubur Rahman, Ahmed Nawsher Alam, Farzana Khan, Ben Swallow, Frances S Mair, Janine Illian, Caroline Trotter, Davina L Hill, Dirk Husmeier, Jason Matthiopoulos, Katie Hampson, Ayesha Sania
May 26, 2022
Descriptive analysis of low versus elevated intracranial pressure on cerebral physiology in adult traumatic brain injury
Frederick A. Zeiler, Ari Ercole, Manuel Cabeleira, Nino Stocchetti, Peter J. Hutchinson, Peter Smielewski, Marek Czosnyka, Audny Anke, Ronny Beer, Bo-Michael Bellander, Erta Beqiri, Andras Buki, Marco Carbonara, Arturo Chieregato, Giuseppe Citerio, Hans Clusmann, Endre Czeiter, Bart Depreitere, Shirin Frisvold, Raimund Helbok, Stefan Jankowski, Daniel Kondziella, Lars-Owe Koskinen, Ana Kowark, David K. Menon, Geert Meyfroidt, Kirsten Moeller, David Nelson, Anna Piippo-Karjalainen, Andreea Radoi, Arminas Ragauskas, Rahul Raj, Jonathan Rhodes, Saulius Rocka, Rolf Rossaint, Juan Sahuquillo, Oliver Sakowitz, Nina Sundström, Riikka Takala, Tomas Tamosuitis, Olli Tenovuo, Andreas Unterberg, Peter Vajkoczy, Alessia Vargiolu, Rimantas Vilcinis, Stefan Wolf, Alexander Younsi, Frederick A. Zeiler
Sep 08, 2021
Engineering Genetic Predisposition in Human Neuroepithelial Stem Cells Recapitulates Medulloblastoma Tumorigenesis.
Miller Huang, Jignesh Tailor, Qiqi Zhen, Aaron H Gillmor, Matthew L Miller, Holger Weishaupt, Justin Chen, Tina Zheng, Emily K Nash, Lauren K McHenry, Zhenyi An, Fubaiyang Ye, Yasuhiro Takashima, James Clarke, Harold Ayetey, Florence MG Cavalli, Betty Luu, Branden S Moriarity, Shirin Ilkhanizadeh, Lukas Chavez, Chunying Yu, Kathreena M Kurian, Thierry Magnaldo, Nicolas Sevenet, Philipp Koch, Steven M Pollard, Peter Dirks, Michael P Snyder, David A Largaespada, Yoon Jae Cho, Joanna J Phillips, Fredrik J Swartling, A Sorana Morrissy, Marcel Kool, Stefan M Pfister, Michael D Taylor, Austin Smith, William A Weiss
Jul 25, 2019
Human neural stem cell cultures provide progenitor cells that are potential cells of origin for brain cancers. However, the extent to which genetic predisposition to tumor formation can be faithfully captured in stem cell lines...
SHH Human pluripotent stem cells Medulloblastoma neuroepithelial stem cells Animals Basal Cell Nevus Syndrome Brain Neoplasms Carcinogenesis DEAD-box RNA Helicases Disease Models Animal Genetic Engineering Genetic Predisposition to Disease Humans Medulloblastoma Mice Mice SCID N-Myc Proto-Oncogene Protein Neoplasm Proteins Neural Stem Cells Neuroepithelial Cells Patched-1 Receptor Pluripotent Stem Cells Stem Cell Transplantation Transplantation Heterologous
Compensatory-reserve-weighted intracranial pressure versus intracranial pressure for outcome association in adult traumatic brain injury
Frederick A. Zeiler, Ari Ercole, Manuel Cabeleira, Erta Beqiri, Tommaso Zoerle, Marco Carbonara, Nino Stocchetti, David K. Menon, Peter Smielewski, Marek Czosnyka, Audny Anke, Ronny Beer, Bo-Michael Bellander, Andras Buki, Giorgio Chevallard, Arturo Chieregato, Giuseppe Citerio, Endre Czeiter, Bart Depreitere, George Eapen, Shirin Frisvold, Raimund Helbok, Stefan Jankowski, Daniel Kondziella, Lars-Owe Koskinen, Geert Meyfroidt, Kirsten Moeller, David Nelson, Anna Piippo-Karjalainen, Andreea Radoi, Arminas Ragauskas, Rahul Raj, Jonathan Rhodes, Saulius Rocka, Rolf Rossaint, Juan Sahuquillo, Oliver Sakowitz, Ana Stevanovic, Nina Sundström, Riikka Takala, Tomas Tamosuitis, Olli Tenovuo, Peter Vajkoczy, Alessia Vargiolu, Rimantas Vilcinis, Stefan Wolf, Alexander Younsi
Jun 06, 2020
Abstract: Background: Compensatory-reserve-weighted intracranial pressure (wICP) has recently been suggested as a supplementary measure of intracranial pressure (ICP) in adult traumatic brain injury (TBI), with a single-center...
Evaluation of the relationship between slow-waves of intracranial pressure, mean arterial pressure and brain tissue oxygen in TBI
Manuel Cabeleira, Peter J. Hutchinson, Marek Czosnyka, Peter Smielewski, Ari Ercole, Audny Anke, Ronny Beer, Bo-Michael Bellander, Erta Beqiri, Andras Buki, Marco Carbonara, Arturo Chieregato, Giuseppe Citerio, Hans Clusmann, Endre Czeiter, Bart Depreitere, Shirin Frisvold, Raimund Helbok, Stefan Jankowski, Danile Kondziella, Lars-Owe Koskinen, Ana Kowark, David K. Menon, Geert Meyfroidt, Kirsten Moeller, David Nelson, Anna Piippo-Karjalainen, Andreea Radoi, Arminas Ragauskas, Rahul Raj, Jonathan Rhodes, Saulius Rocka, Rolf Rossaint, Juan Sahuquillo, Oliver Sakowitz, Nino Stocchetti, Nina Sundström, Riikka Takala, Tomas Tamosuitis, Olli Tenovuo, Peter Vajkoczy, Alessia Vargiolu, Rimantas Vilcinis, Stefan Wolf, Alexander Younsi, Frederick A. Zeiler
Jul 28, 2021
Abstract: Brain tissue oxygen (PbtO2) monitoring in traumatic brain injury (TBI) has demonstrated strong associations with global outcome. Additionally, PbtO2 signals have been used to derive indices thought to be associated...
Descriptive analysis of low versus elevated intracranial pressure on cerebral physiology in adult traumatic brain injury
Frederick A. Zeiler, Ari Ercole, Manuel Cabeleira, Nino Stocchetti, Peter J. Hutchinson, Peter Smielewski, Marek Czosnyka, Audny Anke, Ronny Beer, Bo-Michael Bellander, Erta Beqiri, Andras Buki, Marco Carbonara, Arturo Chieregato, Giuseppe Citerio, Hans Clusmann, Endre Czeiter, Bart Depreitere, Shirin Frisvold, Raimund Helbok, Stefan Jankowski, Daniel Kondziella, Lars-Owe Koskinen, Ana Kowark, David K. Menon, Geert Meyfroidt, Kirsten Moeller, David Nelson, Anna Piippo-Karjalainen, Andreea Radoi, Arminas Ragauskas, Rahul Raj, Jonathan Rhodes, Saulius Rocka, Rolf Rossaint, Juan Sahuquillo, Oliver Sakowitz, Nina Sundström, Riikka Takala, Tomas Tamosuitis, Olli Tenovuo, Andreas Unterberg, Peter Vajkoczy, Alessia Vargiolu, Rimantas Vilcinis, Stefan Wolf, Alexander Younsi
Oct 12, 2020
Low-resolution pressure reactivity index and its derived optimal cerebral perfusion pressure in adult traumatic brain injury
Lennart Riemann, Erta Beqiri, Peter Smielewski, Marek Czosnyka, Nino Stocchetti, Oliver Sakowitz, Klaus Zweckberger, Andreas Unterberg, Alexander Younsi, Audny Anke, Ronny Beer, Bo-Michael Bellander, Andras Buki, Giorgio Chevallard, Arturo Chieregato, Giuseppe Citerio, Endre Czeiter, Bart Depreitere, George Eapen, Shirin Frisvold, Raimund Helbok, Stefan Jankowski, Daniel Kondziella, Lars-Owe Koskinen, Geert Meyfroidt, Kirsten Moeller, David Nelson, Anna Piippo-Karjalainen, Andreea Radoi, Arminas Ragauskas, Rahul Raj, Jonathan Rhodes, Saulius Rocka, Rolf Rossaint, Juan Sahuquillo, Ana Stevanovic, Nina Sundström, Riikka Takala, Tomas Tamosuitis, Olli Tenovuo, Peter Vajkoczy, Alessia Vargiolu, Rimantas Vilcinis, Stefan Wolf
May 26, 2021
Abstract: Background: After traumatic brain injury (TBI), brain tissue can be further damaged when cerebral autoregulation is impaired. Managing cerebral perfusion pressure (CPP) according to computed “optimal CPP” values based...
Cerebrovascular reactivity is not associated with therapeutic intensity in adult traumatic brain injury
Frederick A. Zeiler, Ari Ercole, Erta Beqiri, Manuel Cabeleira, Marcel Aries, Tommaso Zoerle, Marco Carbonara, Nino Stocchetti, Peter Smielewski, Marek Czosnyka, David K. Menon, Audny Anke, Ronny Beer, Bo-Michael Bellander, Andras Buki, Giorgio Chevallard, Arturo Chieregato, Giuseppe Citerio, Endre Czeiter, Bart Depreitere, George Eapen, Shirin Frisvold, Raimund Helbok, Stefan Jankowski, Daniel Kondziella, Lars-Owe Koskinen, Geert Meyfroidt, Kirsten Moeller, David Nelson, Anna Piippo-Karjalainen, Andreea Radoi, Arminas Ragauskas, Rahul Raj, Jonathan Rhodes, Saulius Rocka, Rolf Rossaint, Juan Sahuquillo, Oliver Sakowitz, Ana Stevanovic, Nina Sundström, Riikka Takala, Tomas Tamosuitis, Olli Tenovuo, Peter Vajkoczy, Alessia Vargiolu, Rimantas Vilcinis, Stefan Wolf, Alexander Younsi
Jun 24, 2020
Abstract: Background: Impaired cerebrovascular reactivity in adult traumatic brain injury (TBI) is known to be associated with poor outcome. However, there has yet to be an analysis of the association between the comprehensively...
SARS-CoV-2 within-host diversity and transmission.
Katrina A Lythgoe, Matthew Hall, Luca Ferretti, Mariateresa de Cesare, George MacIntyre-Cockett, Amy Trebes, Monique Andersson, Newton Otecko, Emma L Wise, Nathan Moore, Jessica Lynch, Stephen Kidd, Nicholas Cortes, Matilde Mori, Rebecca Williams, Gabrielle Vernet, Anita Justice, Angie Green, Samuel M Nicholls, M Azim Ansari, Lucie Abeler-Dörner, Catrin E Moore, Timothy EA Peto, David W Eyre, Robert Shaw, Peter Simmonds, David Buck, John A Todd, Oxford Virus Sequencing Analysis Group (OVSG), Thomas R Connor, Shirin Ashraf, Ana da Silva Filipe, James Shepherd, Emma C Thomson, COVID-19 Genomics UK (COG-UK) Consortium, David Bonsall, Christophe Fraser, Tanya Golubchik
Mar 10, 2021
SARS-CoV-2 Omicron is an immune escape variant with an altered cell entry pathway.
Brian J Willett, Joe Grove, Oscar A MacLean, Craig Wilkie, Giuditta De Lorenzo, Wilhelm Furnon, Diego Cantoni, Sam Scott, Nicola Logan, Shirin Ashraf, Maria Manali, Agnieszka Szemiel, Vanessa Cowton, Elen Vink, William T Harvey, Chris Davis, Patawee Asamaphan, Katherine Smollett, Lily Tong, Richard Orton, Joseph Hughes, Poppy Holland, Vanessa Silva, David J Pascall, Kathryn Puxty, Ana da Silva Filipe, Gonzalo Yebra, Sharif Shaaban, Matthew TG Holden, Rute Maria Pinto, Rory Gunson, Kate Templeton, Pablo R Murcia, Arvind H Patel, Paul Klenerman, Susanna Dunachie, PITCH Consortium, COVID-19 Genomics UK (COG-UK) Consortium, John Haughney, David L Robertson, Massimo Palmarini, Surajit Ray, Emma C Thomson
Aug 04, 2022
Low-resolution pressure reactivity index and its derived optimal cerebral perfusion pressure in adult traumatic brain injury
Lennart Riemann, Erta Beqiri, Peter Smielewski, Marek Czosnyka, Nino Stocchetti, Oliver Sakowitz, Klaus Zweckberger, Andreas Unterberg, Alexander Younsi, Audny Anke, Ronny Beer, Bo-Michael Bellander, Andras Buki, Giorgio Chevallard, Arturo Chieregato, Giuseppe Citerio, Endre Czeiter, Bart Depreitere, George Eapen, Shirin Frisvold, Raimund Helbok, Stefan Jankowski, Daniel Kondziella, Lars-Owe Koskinen, Geert Meyfroidt, Kirsten Moeller, David Nelson, Anna Piippo-Karjalainen, Andreea Radoi, Arminas Ragauskas, Rahul Raj, Jonathan Rhodes, Saulius Rocka, Rolf Rossaint, Juan Sahuquillo, Ana Stevanovic, Nina Sundström, Riikka Takala, Tomas Tamosuitis, Olli Tenovuo, Peter Vajkoczy, Alessia Vargiolu, Rimantas Vilcinis, Stefan Wolf
Jun 06, 2020
Abstract: Background: After traumatic brain injury (TBI), brain tissue can be further damaged when cerebral autoregulation is impaired. Managing cerebral perfusion pressure (CPP) according to computed “optimal CPP” values based...
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