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Results: 29
Tracing the origin of adult intestinal stem cells.
Jordi Guiu, Edouard Hannezo, Shiro Yui, Samuel Demharter, Svetlana Ulyanchenko, Martti Maimets, Anne Jørgensen, Signe Perlman, Lene Lundvall, Linn Salto Mamsen, Agnete Larsen, Rasmus H Olesen, Claus Yding Andersen, Lea Langhoff Thuesen, Kristine Juul Hare, Tune H Pers, Konstantin Khodosevich, Benjamin D Simons, Kim B Jensen
Apr 18, 2019
Cannabis and mental health
Background: Cannabis can have an adverse impact on some mental health conditions, while many consumers report using cannabis to manage or improve mental health. Little data exists on how patterns of cannabis use differ by...
Cannabis and Mental Health
Background: Cannabis can induce negative outcomes among consumers with mental health conditions. This study examined medical help-seeking behavior, patterns of adverse effects, and perceived impacts of cannabis among...
Cannabis and mental health
Background: Cannabis can have an adverse impact on some mental health conditions, while many consumers report using cannabis to manage or improve mental health. Little data exists on how patterns of cannabis use differ by...
Cannabis and Mental Health
Background: Cannabis can induce negative outcomes among consumers with mental health conditions. This study examined medical help-seeking behavior, patterns of adverse effects, and perceived impacts of cannabis among...
Agency vs. Stewardship Theory in Local Government Contracted Mobile Apps
This paper examines citizen satisfaction levels with local government contracted mobile platforms and applies two theories of the contracting relationship to them: principal-agent and stewardship theory. It uses survey data to...
Published by: IGI Global Scientific Publishing
Analysis of Features Selected by a Deep Learning Model for Differential Treatment Selection in Depression.
Joseph Mehltretter, Colleen Rollins, David Benrimoh, Robert Fratila, Kelly Perlman, Sonia Israel, Marc Miresco, Marina Wakid, Gustavo Turecki
Feb 04, 2020
Background: Deep learning has utility in predicting differential antidepressant treatment response among patients with major depressive disorder, yet there remains a paucity of research describing how to interpret deep learning...
Theory of visual attention (TVA) applied to rats performing the 5-choice serial reaction time task
Mona El-Sayed Hervig, Chiara Toschi, Anders Petersen, Signe Vangkilde, Ulrik Gether, Trevor W Robbins
Jan 05, 2023
RATIONALE: Attention is compromised in many psychiatric disorders, including attention-deficit/hyperactivity disorder (ADHD). While dopamine and noradrenaline systems have been implicated in ADHD, their exact role in attentional...
ADHD Amphetamine Atipamezole atomoxetine Attention methylphenidate Phenylephrine TVA Visual processing Rats Humans Animals Reaction Time Atomoxetine Hydrochloride Dopamine methylphenidate Amphetamine Attention Deficit Disorder with Hyperactivity Norepinephrine Phenylephrine Central Nervous System Stimulants
Annular versus supra-annular sizing for transcatheter aortic valve replacement in bicuspid aortic valve disease.
Jonathan R Weir-McCall, Adrian Attinger-Toller, Philipp Blanke, Gidon Y Perlman, Stephanie L Sellers, David Wood, John G Webb, Jonathon Leipsic
Sep 28, 2020
BACKGROUND: CT measurement of supra-annular area (SA) has been proposed as an alternative to annular area (AA) for sizing of trancatheter valves in biscuspid aortic valves (BAV). This study examines the reproducibility of SA and...
Aortic stenosis Bicuspid aortic valve Computer tomography Tavr Valvular disease Aged Aged 80 and over Aortic Valve aortic valve stenosis Bicuspid Aortic Valve Disease Computed Tomography Angiography Coronary Angiography Echocardiography Female Heart Valve Diseases Heart valve prosthesis Humans Male Middle Aged Multidetector Computed Tomography Predictive Value of Tests Prosthesis Design Retrospective Studies Severity of Illness Index transcatheter aortic valve replacement Treatment Outcome
Habitual physical activity is associated with lower fasting and greater glucose-induced GLP-1 response in men.
The in-session discourse of unresolved/disorganized psychotherapy patients
L’intériorité pathique des mots
Cesare Del Mastro
Dec 20, 2016
Si la phénoménologie de Michel Henry renvoie l’humain à son ancrage dans la vieauto-affective, comment aborder dans un tel cadre philosophique deux des traitspropres au vivant humain, à savoir le langage et la création...
Published by: Memorial University of Newfoundland
L’intériorité pathique des mots
Cesare Del Mastro
Dec 20, 2016
Si la phénoménologie de Michel Henry renvoie l’humain à son ancrage dans la vieauto-affective, comment aborder dans un tel cadre philosophique deux des traitspropres au vivant humain, à savoir le langage et la création...
Published by: Memorial University of Newfoundland
CALM regulates clathrin-coated vesicle size and maturation by directly sensing and driving membrane curvature.
Sharon E Miller, Signe Mathiasen, Nicholas A Bright, Fabienne Pierre, Bernard T Kelly, Nikolay Kladt, Astrid Schauss, Christien J Merrifield, Dimitrios Stamou, Stefan Höning, David J Owen
Jun 25, 2015
Cell Line Tumor Cell Membrane Cell Shape Clathrin-Coated Vesicles Coated Pits Cell-Membrane Endocytosis Epidermal Growth Factor Fatty Acid-Binding Proteins HeLa Cells Humans Liposomes Monomeric Clathrin Assembly Proteins Protein Structure Tertiary R-SNARE Proteins RNA Interference RNA Small Interfering Transferrin
Effect of the Carer Support Needs Assessment Tool intervention (CSNAT-I) in the Danish specialised palliative care setting
Line Lund, Lone Ross, Morten Aagaard Petersen, Annemette Blach, Elizabeth Rosted, Georg Bollig, Gitte Irene Juhl, Hanne Bollerup Farholt, Helen Winther, Louise Laursen, Marianne Hasse, Signe Weensgaard, Mai-Britt Guldin, Gail Ewing, Gunn Grande, Mogens Groenvold
Nov 02, 2020
Background: The Carer Support Needs Assessment Tool intervention (CSNAT-I) has been shown to improve end-of-life care support for informal caregivers. This study investigated the impact of the CSNAT-I on caregivers of patients...
Effect of the Carer Support Needs Assessment Tool intervention (CSNAT-I) in the Danish specialised palliative care setting
Line Lund, Lone Ross, Morten Aagaard Petersen, Annemette Blach, Elizabeth Rosted, Georg Bollig, Gitte Irene Juhl, Hanne Bollerup Farholt, Helen Winther, Louise Laursen, Marianne Hasse, Signe Weensgaard, Mai-Britt Guldin, Gail Ewing, Gunn Grande, Mogens Groenvold
Nov 03, 2020
BACKGROUND: The Carer Support Needs Assessment Tool intervention (CSNAT-I) has been shown to improve end-of-life care support for informal caregivers. This study investigated the impact of the CSNAT-I on caregivers of patients...
Effect of the Carer Support Needs Assessment Tool intervention (CSNAT-I) in the Danish specialised palliative care setting
Line Lund, Lone Ross, Morten Aagaard Petersen, Annemette Blach, Elizabeth Rosted, Georg Bollig, Gitte Irene Juhl, Hanne Bollerup Farholt, Helen Winther, Louise Laursen, Marianne Hasse, Signe Weensgaard, Mai-Britt Guldin, Gail Ewing, Gunn Grande, Mogens Groenvold
Nov 20, 2020
Background: The Carer Support Needs Assessment Tool intervention (CSNAT-I) has been shown to improve end-of-life care support for informal caregivers. This study investigated the impact of the CSNAT-I on caregivers of patients...
Longitudinal multi-omics analysis identifies early blood-based predictors of anti-TNF therapy response in inflammatory bowel disease.
Neha Mishra, Konrad Aden, Johanna I Blase, Nathan Baran, Dora Bordoni, Florian Tran, Claudio Conrad, Diana Avalos, Charlot Jaeckel, Michael Scherer, Signe B Sørensen, Silja H Overgaard, Berenice Schulte, Susanna Nikolaus, Guillaume Rey, Gilles Gasparoni, Paul A Lyons, Joachim L Schultze, Jörn Walter, Vibeke Andersen, SYSCID Consortium, Emmanouil T Dermitzakis, Stefan Schreiber, Philip Rosenstiel
Oct 25, 2022
BACKGROUND AND AIMS: Treatment with tumor necrosis factor α (TNFα) antagonists in IBD patients suffers from primary non-response rates of up to 40%. Biomarkers for early prediction of therapy success are missing. We investigated...
Longitudinal multi-omics analysis identifies early blood-based predictors of anti-TNF therapy response in inflammatory bowel disease.
Neha Mishra, Konrad Aden, Johanna I Blase, Nathan Baran, Dora Bordoni, Florian Tran, Claudio Conrad, Diana Avalos, Charlot Jaeckel, Michael Scherer, Signe B Sørensen, Silja H Overgaard, Berenice Schulte, Susanna Nikolaus, Guillaume Rey, Gilles Gasparoni, Paul A Lyons, Joachim L Schultze, Jörn Walter, Vibeke Andersen, SYSCID Consortium, Emmanouil T Dermitzakis, Stefan Schreiber, Philip Rosenstiel
Sep 25, 2022
A Complete Electron Microscopy Volume of the Brain of Adult Drosophila melanogaster.
Zhihao Zheng, J Scott Lauritzen, Eric Perlman, Camenzind G Robinson, Matthew Nichols, Daniel Milkie, Omar Torrens, John Price, Corey B Fisher, Nadiya Sharifi, Steven A Calle-Schuler, Lucia Kmecova, Iqbal J Ali, Bill Karsh, Eric T Trautman, John A Bogovic, Philipp Hanslovsky, Gregory SXE Jefferis, Michael Kazhdan, Khaled Khairy, Stephan Saalfeld, Richard D Fetter, Davi D Bock
Feb 07, 2019
Drosophila melanogaster has a rich repertoire of innate and learned behaviors. Its 100,000-neuron brain is a large but tractable target for comprehensive neural circuit mapping. Only electron microscopy (EM) enables complete...
PGBD5 promotes site-specific oncogenic mutations in human tumors
AG Henssen, R Koche, J Zhuang, E Jiang, C Reed, A Eisenberg, E Still, IC MacArthur, E Rodríguez-Fos, S Gonzalez, M Puiggròs, AN Blackford, CE Mason, E de Stanchina, M Gönen, A-K Emde, M Shah, K Arora, C Reeves, ND Socci, E Perlman, CR Antonescu, CWM Roberts, H Steen, E Mullen, SP Jackson, D Torrents, Z Weng, SA Armstrong, A Kentsis
Aug 22, 2017
Evaluating the Clinical Feasibility of an Artificial Intelligence-Powered, Web-Based Clinical Decision Support System for the Treatment of Depression in Adults
Christina Popescu, Grace Golden, David Benrimoh, Myriam Tanguay-Sela, Dominique Slowey, Eryn Lundrigan, Jérôme Williams, Bennet Desormeau, Divyesh Kardani, Tamara Perez, Colleen Rollins, Sonia Israel, Kelly Perlman, Caitrin Armstrong, Jacob Baxter, Kate Whitmore, Marie-Jeanne Fradette, Kaelan Felcarek-Hope, Ghassen Soufi, Robert Fratila, Joseph Mehltretter, Karl Looper, Warren Steiner, Soham Rej, Jordan F Karp, Katherine Heller, Sagar V Parikh, Rebecca McGuire-Snieckus, Manuela Ferrari, Howard Margolese, Gustavo Turecki
Jan 06, 2022
BACKGROUND: Approximately two-thirds of patients with major depressive disorder do not achieve remission during their first treatment. There has been increasing interest in the use of digital, artificial intelligence-powered...
Association of LPA Variants With Risk of Coronary Disease and the Implications for Lipoprotein(a)-Lowering Therapies
Stephen Burgess, Brian A Ference, James R Staley, Daniel F Freitag, Amy M Mason, Sune F Nielsen, Peter Willeit, Robin Young, Praveen Surendran, Savita Karthikeyan, Thomas R Bolton, James E Peters, Pia R Kamstrup, Anne Tybjaerg-Hansen, Marianne Benn, Anne Langsted, Peter Schnohr, Signe Vedel-Krogh, Camilla J Kobylecki, Ian Ford, Chris Packard, Stella Trompet, J Wouter Jukema, Naveed Sattar, Emanuele Di Angelantonio, Danish Saleheen, Joanna MM Howson, Børge G Nordestgaard, Adam S Butterworth, John Danesh, European Prospective Investigation Into Cancer and Nutrition–Cardiovascular Disease (EPIC-CVD) Consortium
Sep 27, 2018
IMPORTANCE: Human genetic studies have indicated that plasma lipoprotein(a) (Lp[a]) is causally associated with the risk of coronary heart disease (CHD), but randomized trials of several therapies that reduce Lp(a) levels by 25%...
Adherence to the World Cancer Research Fund/American Institute for Cancer Research cancer prevention recommendations and risk of in situ breast cancer in the European Prospective Investigation into Cancer and Nutrition (EPIC) cohort.
Nena Karavasiloglou, Anika Hüsing, Giovanna Masala, Carla H van Gils, Renée Turzanski Fortner, Jenny Chang-Claude, Inge Huybrechts, Elisabete Weiderpass, Marc Gunter, Patrick Arveux, Agnès Fournier, Marina Kvaskoff, Anne Tjønneland, Cecilie Kyrø, Christina C Dahm, Helene Tilma Vistisen, Marije F Bakker, Maria-Jose Sánchez, María Dolores Chirlaque López, Carmen Santiuste, Eva Ardanaz, Virginia Menéndez, Antonio Agudo, Antonia Trichopoulou, Anna Karakatsani, Carlo La Vecchia, Eleni Peppa, Domenico Palli, Claudia Agnoli, Salvatore Panico, Rosario Tumino, Carlotta Sacerdote, Salma Tunå Butt, Signe Borgquist, Guri Skeie, Matthias Schulze, Timothy Key, Kay-Tee Khaw, Kostantinos K Tsilidis, Merete Ellingjord-Dale, Elio Riboli, Rudolf Kaaks, Laure Dossus, Sabine Rohrmann, Tilman Kühn
Jan 02, 2020
BACKGROUND:Even though in situ breast cancer (BCIS) accounts for a large proportion of the breast cancers diagnosed, few studies have investigated potential risk factors for BCIS. Their results suggest that some established risk...
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