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Is There Recess on Mars?
The pandemic of 2019 created a multitude of challenges for teachers and students alike. The urgency with which education was forced to transition to a fully online delivery paradigm necessitated a triage and curate process to...
Published by: IGI Global Scientific Publishing
Bilateral Pneumothorax and Subcutaneous Emphysema following Endoscopic Retrograde Cholangiopancreatography
Endoscopic Retrograde Cholangiopancreatography (ERCP) is a widely used diagnostic and therapeutic modality in the management of biliary and pancreatic disease. Some of the complications of the procedure, although rare, may carry...
Citrobacter rodentium is an unstable pathogen showing evidence of significant genomic flux.
Nicola K Petty, Theresa Feltwell, Derek Pickard, Simon Clare, Ana L Toribio, Maria Fookes, Kevin Roberts, Rita Monson, Satheesh Nair, Robert A Kingsley, Richard Bulgin, Siouxsie Wiles, David Goulding, Thomas Keane, Craig Corton, Nicola Lennard, David Harris, David Willey, Richard Rance, Lu Yu, Jyoti S Choudhary, Carol Churcher, Michael A Quail, Julian Parkhill, Gad Frankel, Gordon Dougan, George PC Salmond, Nicholas R Thomson
Jan 14, 2020
Citrobacter rodentium is a natural mouse pathogen that causes attaching and effacing (A/E) lesions. It shares a common virulence strategy with the clinically significant human A/E pathogens enteropathogenic E. coli (EPEC) and...
Animals Citrobacter rodentium DNA Bacterial Disease Models Animal Electrophoresis Gel Pulsed-Field Enterobacteriaceae Infections Female Gene Expression Profiling Gene Rearrangement Genome Bacterial Genomic Instability Humans Interspersed Repetitive Sequences Mice Mice Inbred C57BL Plasmids Prophages Sequence Analysis DNA Virulence
Are multiple physical symptoms a poor prognostic factor or just a marker of depression severity?
Amy Green, Andrew Crawford, Katherine S Button, Nicola Wiles, Tim J Peters, David Nutt, Glyn Lewis
Jul 01, 2014
BACKGROUND: Using data from the GenPod trial this study investigates: (i) if depressed individuals with multiple physical symptoms have a poorer response to antidepressants before and after adjustment for baseline Beck...
Developing Teachers' Knowledge for Teaching in Virtual Contexts
The 2020 worldwide pandemic signaled the COVID-19 crisis as a real threat and forced K-12 schools to move teaching and learning from face-to-face classrooms to online virtual classrooms. Educators searched for a silver lining...
Published by: IGI Global Scientific Publishing
Are multiple physical symptoms a poor prognostic factor or just a marker of depression severity?
Amy Green, Andrew Crawford, Katherine S Button, Nicola Wiles, Tim J Peters, David Nutt, Glyn Lewis
Jul 01, 2014
BACKGROUND: Using data from the GenPod trial this study investigates: (i) if depressed individuals with multiple physical symptoms have a poorer response to antidepressants before and after adjustment for baseline Beck...
Moderators of response to cognitive behavioural therapy as an adjunct to pharmacotherapy for treatment-resistant depression in primary care
Katherine S Button, Nicholas Turner, John Campbell, David Kessler, Willem Kuyken, Glyn Lewis, Tim J Peters, Laura Thomas, Nicola Wiles
Mar 15, 2015
BACKGROUND: Stratified medicine aims to improve clinical and cost-effectiveness by identifying moderators of treatment that indicate differential response to treatment. Cognitive behavioural therapy (CBT) is often offered as...
Moderators of response to cognitive behavioural therapy as an adjunct to pharmacotherapy for treatment-resistant depression in primary care
Katherine S Button, Nicholas Turner, John Campbell, David Kessler, Willem Kuyken, Glyn Lewis, Tim J Peters, Laura Thomas, Nicola Wiles
Mar 15, 2015
BACKGROUND: Stratified medicine aims to improve clinical and cost-effectiveness by identifying moderators of treatment that indicate differential response to treatment. Cognitive behavioural therapy (CBT) is often offered as...
On the GL$_{n}$-eigenvariety and a conjecture of Venkatesh
Let π be a cuspidal, cohomological automorphic representation of GL$_{n}$(A). Venkatesh has suggested that there should exist a natural action of the exterior algebra of a certain motivic cohomology group on the π-part of the...
The feasibility of low intensity psychological therapy for co-occurring depression in adult Autism
Ailsa Russell, Daisy Gaunt, Kate Cooper, Stephen Barton, Jeremy Horwood, David Kessler, Chris Metcalfe, Ian Ensum, Barry Ingham, Jeremy R. Parr, Dheeraj Rai, Nicola Wiles
Aug 01, 2020
Low intensity cognitive behaviour therapy (CBT) including behavioural activation is an evidence based treatment for depression, a condition frequently co-occurring with autism. The feasibility of adapting low intensity CBT for...
Did the Shrew Tame You: An Exploration of Sexual Politics in Shakespeare's <em>The Taming of the Shrew</em>
Marisa Stickel
Jan 01, 0001
This paper explores the sexual politics present in Shakespeare's The Taming of the Shrew, examining the gender roles that influence the relationship between Katherine and Petruccio. By analyzing Petruccio's attempts at taming...
sexual politics gender roles Patriarchy Classical Literature and Philology Feminist, Gender, and Sexuality Studies Other Classics Other Feminist, Gender, and Sexuality Studies Other Theatre and Performance Studies Women's Studies
Published by: Winthrop University
Protocol for a feasibility study and randomised pilot trial of a low intensity psychological intervention for depression in adults with autism
Ailsa Russell, Katherine Cooper, Stephen Barton, Ian Ensum, Daisy Gaunt, Jeremy Horwood, Barry Ingham, David Kessler, Chris Metcalfe, Dheeraj Rai, Jeremy Parr, Nicola Wiles
Dec 03, 2017
IntroductionHigh rates of co-occurring depression are reported in Autism Spectrum Disorder (ASD), a neurodevelopmental condition characterised by social communication impairments and repetitive behaviours. Cognitive behavioural...
A pilot randomised controlled trial of cognitive behavioural therapy for antenatal depression.
Alison Burns, Heather O'Mahen, Helen Baxter, Kristina Bennert, Nicola Wiles, Paul Ramchandani, Katrina Turner, Debbie Sharp, Joanna Thorn, Sian Noble, Jonathan Evans
Jan 08, 2019
BACKGROUND: Few trials have evaluated the effectiveness of psychological treatment in improving depression by the end of pregnancy. This is the first pilot randomised controlled trial (RCT) of individual cognitive behavioural...
Protocol for a feasibility study and randomised pilot trial of a low intensity psychological intervention for depression in adults with autism
Ailsa Russell, Katherine Cooper, Stephen Barton, Ian Ensum, Daisy Gaunt, Jeremy Horwood, Barry Ingham, David Kessler, Chris Metcalfe, Dheeraj Rai, Jeremy Parr, Nicola Wiles
Dec 03, 2017
IntroductionHigh rates of co-occurring depression are reported in Autism Spectrum Disorder (ASD), a neurodevelopmental condition characterised by social communication impairments and repetitive behaviours. Cognitive behavioural...
The feasibility of low intensity psychological therapy for co-occurring depression in adult Autism
Ailsa Russell, Daisy Gaunt, Kate Cooper, Stephen Barton, Jeremy Horwood, David Kessler, Chris Metcalfe, Ian Ensum, Barry Ingham, Jeremy R. Parr, Dheeraj Rai, Nicola Wiles
Aug 01, 2020
Low intensity cognitive behaviour therapy (CBT) including behavioural activation is an evidence based treatment for depression, a condition frequently co-occurring with autism. The feasibility of adapting low intensity CBT for...
Regulation of nerve growth and patterning by cell surface protein disulphide isomerase.
Geoffrey MW Cook, Catia Sousa, Julia Schaeffer, Katherine Wiles, Prem Jareonsettasin, Asanish Kalyanasundaram, Eleanor Walder, Catharina Casper, Serena Patel, Pei Wei Chua, Gioia Riboni-Verri, Mansoor Raza, Nol Swaddiwudhipong, Andrew Hui, Ameer Abdullah, Saj Wajed, Roger J Keynes
Aug 19, 2020
Contact repulsion of growing axons is an essential mechanism for spinal nerve patterning. In birds and mammals the embryonic somites generate a linear series of impenetrable barriers, forcing axon growth cones to traverse one...
Axon guidance chicken developmental biology human neuroscience rat repeat patterning somite Spinal nerve Animals Astrocytes Axon guidance Cell Line Chick Embryo Chickens developmental biology Gene Knockdown Techniques Growth Cones Humans Membrane Proteins Neurosciences Nitric oxide Procollagen-Proline Dioxygenase Protein Disulfide-Isomerases Rats Signal Transduction Somites Spinal Nerves
Lt. Wes Wiles Named 2017 Optimist Club Officer of the Year for Winthrop
Winthrop University
Jan 01, 0001
The Optimist Club presents the Officer of the Year Award to one officer from Winthrop Police, Rock Hill Police, York County Sheriff's Office and the South Carolina Highway Patrol who goes above and beyond the call of duty.
Published by: Winthrop University
Regulation of nerve growth and patterning by cell surface protein disulphide isomerase
Geoffrey MW Cook, Catia Sousa, Julia Schaeffer, Katherine Wiles, Prem Jareonsettasin, Asanish Kalyanasundaram, Eleanor Walder, Catharina Casper, Serena Patel, Pei Wei Chua, Gioia Riboni-Verri, Mansoor Raza, Nol Swaddiwudhipong, Andrew Hui, Ameer Abdullah, Saj Wajed, Roger J Keynes
Jun 04, 2020
Baseline results from the UK SIGNIFY study
S Saya, E Killick, S Thomas, N Taylor, EK Bancroft, J Rothwell, S Benafif, A Dias, C Mikropoulos, J Pope, A Chamberlain, R Gunapala, SIGNIFY Study Steering Committee, L Izatt, L Side, L Walker, S Tomkins, J Cook, J Barwell, V Wiles, L Limb, D Eccles, MO Leach, S Shanley, FJ Gilbert, H Hanson, D Gallagher, B Rajashanker, RW Whitehouse, D-M Koh, SA Sohaib, DG Evans, RA Eeles
Mar 08, 2017
Psychosocial effects of whole-body MRI screening in adult high-risk pathogenic TP53 mutation carriers
Elizabeth K Bancroft, Sibel Saya, Emma Brown, Sarah Thomas, Natalie Taylor, Jeanette Rothwell, Jennifer Pope, Anthony Chamberlain, Elizabeth Page, Sarah Benafif, Helen Hanson, Alexander Dias, Christos Mikropoulos, Louise Izatt, Lucy Side, Lisa Walker, Alan Donaldson, Jackie A Cook, Julian Barwell, Vicki Wiles, Lauren Limb, Diana M Eccles, Martin O Leach, Susan Shanley, Fiona J Gilbert, David Gallagher, Balashanmugam Rajashanker, Richard W Whitehouse, Dow-Mu Koh, S Aslam Sohaib, D Gareth Evans, Rosalind A Eeles, Leslie G Walker
Sep 25, 2019
Li-Fraumeni Syndrome MRI TP53 gene pathogenic variant case controlled study Psychosocial Adult Female Genetic Predisposition to Disease Germ-Line Mutation Heterozygote Humans Li-Fraumeni Syndrome Magnetic Resonance Imaging Male Middle Aged Neoplasms Risk Factors Tumor Suppressor Protein p53 Whole Body Imaging Young Adult
Thiopurine monotherapy is effective in ulcerative colitis but significantly less so in Crohn’s disease
Evangelos Stournaras, Wendi Qian, Apostolos Pappas, You Yi Hong, Rasha Shawky, UK IBD BioResource Investigators, Tim Raine, Miles Parkes, UK IBD BioResource Investigators, Tariq Ahmad, Nick Kennedy, Peter Irving, Natalie Prescott, Charlie Lees, John Mansfield, Chris Lamb, Jack Satsangi, Alison Simmons, Alisa Hart, Sreedhar Subramanian, Chris Probert, Richard Shenderey, Anton Gunasekera, Klaartje Bel Kok, Babur Javaid, Leena Sinha, Salil Singh, Cathryn Preston, Mark Jarvis, Ruth Penn, Anjan Dhar, Achuth Shenoy, Kath Phillis, Arabis Oglesby, Jude Tilbury, Glyn Scott, Joseph Collum, Martyn Carter, Jamie Barbour, John Gordon, John Ramage, Ganesh Sivagi, Phil Roberts, Monica Bose, Shaji Sebastian, Joy Wilkins, Paul Banim, Alexana Kent, Ajay Verma, Dawn Warren, Alan Wiles, Matthew Johnson, Konrad Koss, Chirag Oza, Khalid Elamin, Annette Woods, Bijay Baburajan, Chris MacDonald, Byron Theron, Mark Tremelling, Udi Shmueli, Roisin Bevan, Jimmy Limdi, Prakash Nair, Deven Vani, Stephen Lewis, Michelle Baker-Moffat, Gordon Moran, Simon McLaughlin, Aminda de Silva, John Beckly, Anew Cole, Charles Murray, Alan Lobo, Melissa Smith, Sanju Mathew, John Saunders, Helen Steed, Matthew Brookes, Juliette Loehry, Monira Rahman, Jeff Butterworth, Ajay Muddu, Katie Clark, Christian Selinger, Arvind Ramadas, John McLaughlin, Richard Pollok, Colin Rees, Simon Panter, David Hobday, Stephen Foley, Vinod Patel, Emma Wesley, Daniel Gavin, Cathryn Edwards, Stuart Bloom, Chuka Nwokolo, John deCaestecker, Mina Hanna, Albert Davies, Laura Hancock, Fraser Cummings, Subramaniam Ramakrishnan, Theresa Tindall, Jonathan Landy, Richard Appleby, Dan Sharpstone, Andy Li, Richard Keld, Lin Mear, Anne Philips, Horace Willia, Laura Hancock Ben Warner, Dharmaraj Durai, Elaine Brinkworth, Zahid Mahmood, Rachel Cooney
Oct 06, 2020
Objective: Thiopurines are widely used as maintenance therapy in inflammatory bowel disease (IBD) but the evidence base for their use is sparse and their role increasingly questioned. Using the largest series reported to date...