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Robot seeks public library websites
UKOLN has been active recently analysing UK Public Library websites. Brian Kelly, Sarah Ormes and Ian Peacock report on their findings.
Dangerous diagnostics? Regulatory reform in the genomic era
Molecular diagnostics are expanding rapidly yet many have not been externally evaluated. Kelly Holloway and colleagues identify failings in the regulatory system and report on recent efforts at reform
Robot seeks public library websites
UKOLN has been active recently analysing UK Public Library websites. Brian Kelly, Sarah Ormes and Ian Peacock report on their findings.
Pandemic Participation
This article revisits the three foundational principles of Participatory Mapping practice identified in Good practices in participatory mapping. These include processes that strive for transparency, are unencumbered by time, and...
Published by: IGI Global Scientific Publishing
The COVID-19 pandemic and problematic usage of the internet
Christine Lochner, Lucy Albertella, Martin Kidd, Zelal Kilic, Konstantinos Ioannidis, Jon E Grant, Murat Yücel, Dan J Stein, Samuel R Chamberlain
Aug 16, 2022
BACKGROUND: The coronavirus disease 19 (COVID-19) has led to increased reliance on the internet. How problematic usage of the internet (PUI) and COVID-19 related stress and other clinical variables relate, is unknown. We...
Positively selected modifications in the pore of TbAQP2 allow pentamidine to enter Trypanosoma brucei.
Ali H Alghamdi, Jane C Munday, Gustavo Daniel Campagnaro, Dominik Gurvic, Fredrik Svensson, Chinyere E Okpara, Arvind Kumar, Juan Quintana, Maria Esther Martin Abril, Patrik Milić, Laura Watson, Daniel Paape, Luca Settimo, Anna Dimitriou, Joanna Wielinska, Graeme Smart, Laura F Anderson, Christopher M Woodley, Siu Pui Ying Kelly, Hasan MS Ibrahim, Fabian Hulpia, Mohammed I Al-Salabi, Anthonius A Eze, Teresa Sprenger, Ibrahim A Teka, Simon Gudin, Simone Weyand, Mark Field, Christophe Dardonville, Richard R Tidwell, Mark Carrington, Paul O'Neill, David W Boykin, Ulrich Zachariae, Harry P De Koning
Nov 02, 2020
Mutations in the Trypanosoma brucei aquaporin AQP2 are associated with resistance to pentamidine and melarsoprol. We show that TbAQP2 but not TbAQP3 was positively selected for increased pore size from a common ancestor...
Mutational landscape of normal epithelial cells in Lynch Syndrome patients.
Bernard CH Lee, Philip S Robinson, Tim HH Coorens, Helen HN Yan, Sigurgeir Olafsson, Henry Lee-Six, Mathijs A Sanders, Hoi Cheong Siu, James Hewinson, Sarah SK Yue, Wai Yin Tsui, Annie SY Chan, Anthony KW Chan, Siu Lun Ho, Peter J Campbell, Inigo Martincorena, Simon JA Buczacki, Siu Tsan Yuen, Suet Yi Leung, Michael R Stratton
Jun 29, 2022
Lynch Syndrome (LS) is an autosomal dominant disease conferring a high risk of colorectal cancer due to germline heterozygous mutations in a DNA mismatch repair (MMR) gene. Although cancers in LS patients show elevated somatic...
Water: Place. Experience. In Literature, Visual & Performing Arts
Kelly Richardson, Emily Morgan and Laura Dougherty will engage in a ten-week collaborative project with theatre and dance students. Drawing from students in these two performance disciplines, we will, as a group, develop a site...
Published by: Winthrop University
Highway to Hell? Images of the American Road in Kelly Reichardt's<i>Old Joy</i>,<i>Wendy and Lucy</i>, and<i>Meek's Cutoff</i>
This article examines representations of the road in the work of independent Florida-born film director Kelly Reichardt. Reading Reichardt's so-called Oregon trilogy,Old...
DIARMUID HESTER
Dec 10, 2018
Measurement of the problematic usage of the Internet unidimensional quasitrait continuum with item response theory.
Jeggan Tiego, Christine Lochner, Konstantinos Ioannidis, Matthias Brand, Dan J Stein, Murat Yücel, Jon E Grant, Samuel R Chamberlain
Feb 19, 2021
Problematic usage of the internet (PUI) describes maladaptive use of online resources and is recognized as a growing worldwide issue. Here, we refined the Internet Addiction Test (IAT) for use as a screening tool to measure...
Mutational landscape of normal epithelial cells in Lynch Syndrome patients.
Bernard CH Lee, Philip S Robinson, Tim HH Coorens, Helen HN Yan, Sigurgeir Olafsson, Henry Lee-Six, Mathijs A Sanders, Hoi Cheong Siu, James Hewinson, Sarah SK Yue, Wai Yin Tsui, Annie SY Chan, Anthony KW Chan, Siu Lun Ho, Peter J Campbell, Inigo Martincorena, Simon JA Buczacki, Siu Tsan Yuen, Suet Yi Leung, Michael R Stratton
May 17, 2022
Lynch Syndrome (LS) is an autosomal dominant disease conferring a high risk of colorectal cancer due to germline heterozygous mutations in a DNA mismatch repair (MMR) gene. Although cancers in LS patients show elevated somatic...
Validation of the PICIN solver for 2D coastal flows
A recent paper Kelly et al. (2015) [SIAM Journal on Scientific Computing 37 (3), B403-B424.] detailed a full particle Particle-In-Cell solver for incompressible free surface flows with two-way fluid-structure interaction...
A Cartesian cut cell based two-way strong fluid-solid coupling algorithm for 2D floating bodies
In a recent paper Kelly et al. (2015) [PICIN: A Particle-In-Cell solver for incompressible free surface flows with two-way fluid-solid coupling. SIAM Journal on Scientific Computing 37 (3), B403-24.] detailed the PICIN full...
Validation of the PICIN solver for 2D coastal flows
A recent paper Kelly et al. (2015) [SIAM Journal on Scientific Computing 37 (3), B403-B424.] detailed a full particle Particle-In-Cell solver for incompressible free surface flows with two-way fluid-structure interaction...
Origen's Johannine Trinitarian Theology of Love
Pui Him Ip
Feb 28, 2022
Origen is the first Christian who proposed a systematically trinitarian theology of love. This has largely escaped the attention of theologians and remains underexplored. One notable consequence is that this has severely limited...
A Cartesian cut cell based two-way strong fluid-solid coupling algorithm for 2D floating bodies
In a recent paper Kelly et al. (2015) [PICIN: A Particle-In-Cell solver for incompressible free surface flows with two-way fluid-solid coupling. SIAM Journal on Scientific Computing 37 (3), B403-24.] detailed the PICIN full...
T cell Allorecognition Pathways in Solid Organ Transplantation.
Transplantation is unusual in that T cells can recognize alloantigen by at least two distinct pathways: as intact MHC alloantigen on the surface of donor cells via the direct pathway; and as self-restricted processed alloantigen...
T cell allorecognition T follicular helper cell chronic allograft vasculopathy cytotoxic CD8 T cells exhaustion Germinal Center indirect presentation Transplantation Dendritic Cells Graft Rejection Histocompatibility Antigens Class II Humans Isoantibodies Isoantigens Organ Transplantation T-Lymphocytes Cytotoxic T-Lymphocytes Helper-Inducer T-Lymphocytes Regulatory Transplantation Homologous
Application of Multimedia Data Feature Extraction Technology in Folk Art Creation
Ying-ying Gong
Jan 01, 2024
In the intelligent background, in order to carry out the folk art creation more conveniently, this article integrates the new technology of multimedia data features into the folk art creation to achieve the sustainable...
Published by: IGI Global Scientific Publishing
Positively selected modifications in the pore of TbAQP2 allow pentamidine to enter Trypanosoma brucei
Ali H Alghamdi, Jane C Munday, Gustavo Daniel Campagnaro, Dominik Gurvic, Fredrik Svensson, Chinyere E Okpara, Arvind Kumar, Juan Quintana, Maria Esther Martin Abril, Patrik Milić, Laura Watson, Daniel Paape, Luca Settimo, Anna Dimitriou, Joanna Wielinska, Graeme Smart, Laura F Anderson, Christopher M Woodley, Siu Pui Ying Kelly, Hasan MS Ibrahim, Fabian Hulpia, Mohammed I Al-Salabi, Anthonius A Eze, Teresa Sprenger, Ibrahim A Teka, Simon Gudin, Simone Weyand, Mark Field, Christophe Dardonville, Richard R Tidwell, Mark Carrington, Paul O'Neill, David W Boykin, Ulrich Zachariae, Harry P De Koning
Sep 05, 2020
Adverse Childhood Experiences and Alcohol Consumption in Midlife and Early Old-Age.
AIMS: To examine the individual and cumulative effects of adverse childhood experiences (ACEs) on alcohol consumption in midlife and early old-age, and the role of ACEs in 10-year drinking trajectories across midlife. METHODS...
Problematic use of the internet during the COVID-19 pandemic
Biljana Gjoneska, Marc N Potenza, Julia Jones, Ornella Corazza, Natalie Hall, Célia MD Sales, Edna Grünblatt, Giovanni Martinotti, Julius Burkauskas, Anna Maria Werling, Susanne Walitza, Joseph Zohar, José M Menchón, Orsolya Király, Samuel R Chamberlain, Naomi A Fineberg, Zsolt Demetrovics
Jan 06, 2022
With the onset of the COVID-19 pandemic and the accelerated spread of the SARS-CoV-2 virus came jurisdictional limitations on mobility of citizens and distinct alterations in their daily routines. Confined to their homes, many...
Transplantation of Human Cortically-Specified Neuroepithelial Progenitor Cells Leads to Improved Functional Outcomes in a Mouse Model of Stroke.
Rehnuma Islam, Stasja Drecun, Balazs V Varga, Ilan Vonderwalde, Ricky Siu, Andras Nagy, Cindi M Morshead
Jun 25, 2021
Stroke is a leading cause of death and long-term disability worldwide. Current therapeutic options are limited in terms of their time for implementation and efficacy in promoting recovery. Cell transplantation has been shown to...
Mahony Stepping Down; Trustees Soon to Name Interim
Winthrop University
Jan 01, 0001
HIGHLIGHTS Mahony has been selected to serve as president of the Southern Illinois University System, and his appointment will be voted on Thursday, Dec. 5, by the SIU Board of Trustees. He will start his new position on March...
Published by: Winthrop University
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