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Impact of Thymectomy on the Peripheral T Cell Pool in the Context of SIV Infection
Sarah Tuttleton Arron
Jan 01, 0001
The thymus is the primary lymphoid organ responsible for T cell production. It is of particular interest in the context of human immunodeficiency virus (HIV)-l infection, in which the progressive loss of CD4+ T cells leads to...
Published by: Rockefeller University
The use of oral fluids to monitor key pathogens in porcine respiratory disease complex.
Juan Hernandez-Garcia, Nardy Robben, Damien Magnée, Thomas Eley, Ian Dennis, Sara M Kayes, Jill R Thomson, Alexander W Tucker
May 05, 2017
BACKGROUND: The usefulness of oral fluid (OF) sampling for surveillance of infections in pig populations is already accepted but its value as a tool to support investigations of porcine respiratory disease complex (PRDC) has...
The decreased replicative capacity of simian immunodeficiency virus SIVmac239?nef is manifest in cultures of immature dendritic cells and T cells
Transmission of simian immunodeficiency virus SIVmac239?nef (?nef) to macaques results in attenuated replication of the virus in most animals and ultimately induces protection against challenge with some pathogenic, wild- type...
T lymphocyte receptor cell maturation Coculture dendritic cell Simian Immunodeficiency Virus T lymphocyte virus transmission
Published by: Rockefeller University
Ensuring Core Competencies for Cybersecurity Specialists
Within an organization, it is critical that all employees possess a security awareness and thus play a part in the protection of said organization's information assets. Some employees will have key roles and responsibilities and...
Published by: IGI Global Scientific Publishing
Increased macrophage infection upon subcutaneous inoculation of rhesus macaques with simian immunodeficiency virus-loaded dendritic cells or T cells but not with cell-free virus
Information on the establishment of immunodeficiency virus infection through transmission of infected cells is sparse. Dendritic cells (DCs) and T cells may be central to the onset and subsequent spread of infection following...
dendritic cell Immunohistochemistry In Situ Hybridization Macaca macrophage Simian Immunodeficiency Virus T lymphocyte
Published by: Rockefeller University
Early protection against pathogenic virus infection at a mucosal challenge site after vaccination with attenuated simian immunodeficiency virus
Atraumatic application of attenuated SIVmac23?nef vaccine to the tonsils of rhesus macaques provided protection against challenge 26 weeks later with infectious SIVmac251 applied through this route. Early events at the mucosal...
cell maturation immune response Lymphoid Tissue mucosa associated lymphoid tissue lymphoma pathogenicity Simian Immunodeficiency Virus t lymphocyte activation virus transmission
Published by: Rockefeller University
Atraumatic oral spray immunization with replication-deficient viral vector vaccines
The development of needle-free vaccines is one of the recently defined "grand challenges in global health" (H. Varmus, R. Klausner, R. Klausner, R. Zerhouni, T. Acharya, A. S. Daar, and P. A. Singer, Science 302:398-399, 2003)....
Published by: Rockefeller University
The IKKbeta subunit of IkappaB kinase (IKK) is essential for nuclear factor kappaB activation and prevention of apoptosis.
The IkappaB kinase (IKK) complex is composed of three subunits, IKKalpha, IKKbeta, and IKKgamma (NEMO). While IKKalpha and IKKbeta are highly similar catalytic subunits, both capable of IkappaB phosphorylation in vitro, IKKgamma...
A multi-decadal record of oceanographic changes of the past ~165 years (1850-2015 AD) from Northwest of Iceland.
Margit H Simon, Francesco Muschitiello, Amandine A Tisserand, Are Olsen, Matthias Moros, Kerstin Perner, Siv Tone Bårdsnes, Trond M Dokken, Eystein Jansen
Oct 15, 2020
Extending oceanographic data beyond the instrumental period is highly needed to better characterize and understand multi-decadal to centennial natural ocean variability. Here, a stable isotope record at unprecedented temporal...
Musicians’ views on the role of reading music in learning, performance, and understanding
Reading music notation is not an easy skill to acquire and can take years of training to master. In addition, it is not strictly necessary to be able to read music to make music. Nevertheless, music teaching and learning in the...
Citizen Adoption in E-Government Systems
Electronic Government (e-Government) refers to a system of information, communication and interaction between government and its citizens. E-Government adoption has been studied for more than a decade with several meta-analytic...
Published by: IGI Global Scientific Publishing
Non-smooth Hopf-type bifurcations arising from impact–friction contact events in rotating machinery
We analyse the novel dynamics arising in a nonlinear rotor dynamic system by investigating the discontinuity-induced bifurcations corresponding to collisions with the rotor housing (touchdown bearing surface interactions). The...
Surveillance recommendations for DICER1 pathogenic variant carriers
Jette J Bakhuizen, Helen Hanson, Karin van der Tuin, Fiona Lalloo, Marc Tischkowitz, Karin Wadt, Marjolijn CJ Jongmans, SIOPE Host Genome Working Group, CanGene-CanVar Clinical Guideline Working Group, Expert Network Members
Oct 01, 2021
DICER1 syndrome is a rare genetic disorder that predisposes to a wide spectrum of tumors. Developing surveillance protocols for this syndrome is challenging because uncertainty exists about the clinical efficacy of surveillance...
Phyloepidemiological analysis reveals that viral divergence led to the paucity of SIVmus/gsn/mon infections in wild populations
F Schmidt, F Liegeois, EJD Greenwood, M LeBreton, J Lester, L Deleplancque, M Peeters, A Aghokeng, U Tamoufe, JLD Diffo, JM Takuo, ND Wolfe, E Leroy, F Rouet, JL Heeney
Mar 03, 2017
Human immunodeficiency virus subtype-1 (HIV-1) is the result of cross-species transmission of simian immunodeficiency virus from chimpanzees (SIVcpz). SIVcpz is a chimeric virus which shares common ancestors with viruses...
A multi-decadal record of oceanographic changes of the past ~165 years (1850-2015 AD) from Northwest of Iceland
Margit H. Simon, Francesco Muschitiello, Amandine A. Tisserand, Are Olsen, Matthias Moros, Kerstin Perner, Siv Tone Bårdsnes, Trond M. Dokken, Eystein Jansen
Sep 29, 2020
Extending oceanographic data beyond the instrumental period is highly needed to better characterize and understand multi-decadal to centennial natural ocean variability. Here, a stable isotope record at unprecedented temporal...
Hearing where the eyes see
To reduce sensory uncertainty, humans combine cues from multiple senses. However, in everyday life, many co‐occurring cues are irrelevant to the task at hand. How do humans know which cues to ignore? And does this ability change...
The Effects of Explicit and Implicit Cognitive Factors on the Learning Patterns in the Iowa Gambling Task
The Iowa Gambling Task (IGT) has become a standard tool in the area of decision making, but recent studies have indicated that cognitive factors might distort the implicit learning expected from the original design of the task....
Published by: Digital Commons @ Texas A&M University-San Antonio
High Trait Anxiety Enhances Optimal Integration of Auditory and Visual Threat Cues
Background
Emotion perception is essential to human interaction and relies on effective integration of emotional cues across sensory modalities. Despite initial evidence for anxiety-related biases in multisensory...
Emotion perception is essential to human interaction and relies on effective integration of emotional cues across sensory modalities. Despite initial evidence for anxiety-related biases in multisensory...
Anxiety emotion maximum likelihood estimation Multisensory processing negative bias race model /dk/atira/pure/subjectarea/asjc/3200/3205 name=Experimental and Cognitive Psychology /dk/atira/pure/subjectarea/asjc/1200/1201 name=Arts and Humanities (miscellaneous) /dk/atira/pure/subjectarea/asjc/3200/3203 name=Clinical Psychology /dk/atira/pure/subjectarea/asjc/2700/2738 name=Psychiatry and Mental health /dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_being name=SDG 3 - Good Health and Well-being
Human autoantibodies against the 54 kDa protein of the signal recognition particle block function at multiple stages.
Non-smooth Hopf-type bifurcations arising from impact–friction contact events in rotating machinery
We analyse the novel dynamics arising in a nonlinear rotor dynamic system by investigating the discontinuity-induced bifurcations corresponding to collisions with the rotor housing (touchdown bearing surface interactions). The...
Experience in judging intent to harm modulates parahippocampal activity
Does visual experience in judging intent to harm change our brain responses? And if it does, what are the mechanisms affected? We addressed these questions by studying the abilities of Closed Circuit Television (CCTV) operators...
Three ancient hormonal cues co-ordinate shoot branching in a moss.
Yoan Coudert, Wojtek Palubicki, Karin Ljung, Ondrej Novak, Ottoline Leyser, C Jill Harrison
Jun 26, 2015
Physcomitrella apical dominance branching developmental biology gametophyte plant biology Stem Cells Biological Transport Body Patterning Bryopsida Cytokinins Gene Expression Regulation Plant Indoleacetic Acids Lactones Models Biological Morphogenesis Mutation Plant Epidermis Plant Growth Regulators Plant Proteins Plant Shoots Plants Genetically Modified
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