Depletion of Macrophages Improves Therapeutic Response to Gemcitabine in Murine Pancreas Cancer.
Soeren M Buchholz,
Robert G Goetze,
Shiv K Singh,
Christoph Ammer-Herrmenau,
Frances M Richards,
Duncan I Jodrell,
Malte Buchholz,
Patrick Michl,
Volker Ellenrieder,
Elisabeth Hessmann,
Albrecht Neesse
Sep 01, 2020
BACKGROUND: The tumor microenvironment (TME) is composed of fibro-inflammatory cells and extracellular matrix (ECM) components. However, the exact contribution of the various TME compartments towards therapeutic response is...