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Convex regularization in statistical inverse learning problems
We consider a statistical inverse learning problem, where the task is to estimate a function f based on noisy point evaluations of Af, where A is a linear operator. The function Af is evaluated at i.i.d. random design points...
Convex regularization in statistical inverse learning problems
We consider a statistical inverse learning problem, where the task is to estimate a function f based on noisy point evaluations of Af, where A is a linear operator. The function Af is evaluated at i.i.d. random design points...
Relationships between lower-limb kinematics and block phase performance in a cross section of sprinters
This study investigated lower-limb kinematics to explain the techniques used to achieve high levels of sprint start performance. A cross-sectional design was used to examine relationships between specific technique variables...
A practical guide to single-cell RNA-sequencing for biomedical research and clinical applications.
RNA sequencing (RNA-seq) is a genomic approach for the detection and quantitative analysis of messenger RNA molecules in a biological sample and is useful for studying cellular responses. RNA-seq has fueled much discovery and...
Competitive swimmers with hypermobility have strength and fatigue deficits in shoulder medial rotation
B. Liaghat, B. Juul-Kristensen, T Frydendal, C. Larsen, K. Sogaard, Aki Iikka Tapio Salo
Apr 01, 2018
Generalised Joint Hypermobility including shoulder hypermobility (GJHS) in swimmers is considered an intrinsic risk factor for shoulder injuries. The aim was to investigate the association of GJHS with shoulder strength...
Relationships between lower-limb kinematics and block phase performance in a cross section of sprinters
This study investigated lower-limb kinematics to explain the techniques used to achieve high levels of sprint start performance. A cross-sectional design was used to examine relationships between specific technique variables...
Lower limb joint kinetics during the first stance phase in athletics sprinting
This study analysed the first stance phase joint kinetics of three elite sprinters to improve the understanding of technique and investigate how individual differences in technique could influence the resulting levels of...
Competitive swimmers with hypermobility have strength and fatigue deficits in shoulder medial rotation
B. Liaghat, B. Juul-Kristensen, T Frydendal, C. Larsen, K. Sogaard, Aki Iikka Tapio Salo
Apr 01, 2018
Generalised Joint Hypermobility including shoulder hypermobility (GJHS) in swimmers is considered an intrinsic risk factor for shoulder injuries. The aim was to investigate the association of GJHS with shoulder strength...
T cell fate and clonality inference from single-cell transcriptomes.
Michael JT Stubbington, Tapio Lönnberg, Valentina Proserpio, Simon Clare, Anneliese O Speak, Gordon Dougan, Sarah A Teichmann
May 16, 2019
We developed TraCeR, a computational method to reconstruct full-length, paired T cell receptor (TCR) sequences from T lymphocyte single-cell RNA sequence data. TraCeR links T cell specificity with functional response by...
Lower limb joint kinetics during the first stance phase in athletics sprinting
This study analysed the first stance phase joint kinetics of three elite sprinters to improve the understanding of technique and investigate how individual differences in technique could influence the resulting levels of...
Single-cell analysis of CD4+ T-cell differentiation reveals three major cell states and progressive acceleration of proliferation.
Valentina Proserpio, Andrea Piccolo, Liora Haim-Vilmovsky, Gozde Kar, Tapio Lönnberg, Valentine Svensson, Jhuma Pramanik, Kedar Nath Natarajan, Weichao Zhai, Xiuwei Zhang, Giacomo Donati, Melis Kayikci, Jurij Kotar, Andrew NJ McKenzie, Ruddy Montandon, Oliver Billker, Steven Woodhouse, Pietro Cicuta, Mario Nicodemi, Sarah A Teichmann
May 16, 2019
BACKGROUND: Differentiation of lymphocytes is frequently accompanied by cell cycle changes, interplay that is of central importance for immunity but is still incompletely understood. Here, we interrogate and quantitatively model...
Adaptive Immunity CD4+ T cells Cell Cycle DIFFERENTIATION Live imaging Single-cell RNA-seq Animals CD4-Positive T-Lymphocytes Cell Differentiation Cell Proliferation Cells Cultured Cytokines Female Gene Expression Profiling Malaria Mice Mice Inbred C57BL Models Biological Sequence Analysis RNA Single-Cell Analysis Transcriptome
Artificial intelligence in nursing
Charlene Esteban Ronquillo, Laura-Maria Peltonen, Lisiane Pruinelli, Charlene H Chu, Suzanne Bakken, Ana Beduschi, Kenrick Cato, Nicholas Hardiker, Alain Junger, Martin Michalowski, Rune Nyrup, Samira Rahimi, Donald Nigel Reed, Tapio Salakoski, Sanna Salanterä, Nancy Walton, Patrick Weber, Thomas Wiegand, Maxim Topaz
Mar 23, 2021
Single-cell RNA-seq and computational analysis using temporal mixture modelling resolves Th1/Tfh fate bifurcation in malaria.
Tapio Lönnberg, Valentine Svensson, Kylie R James, Daniel Fernandez-Ruiz, Ismail Sebina, Ruddy Montandon, Megan SF Soon, Lily G Fogg, Arya Sheela Nair, Urijah Liligeto, Michael JT Stubbington, Lam-Ha Ly, Frederik Otzen Bagger, Max Zwiessele, Neil D Lawrence, Fernando Souza-Fonseca-Guimaraes, Patrick T Bunn, Christian R Engwerda, William R Heath, Oliver Billker, Oliver Stegle, Ashraful Haque, Sarah A Teichmann
Sep 18, 2020
Differentiation of naïve CD4+ T cells into functionally distinct T helper subsets is crucial for the orchestration of immune responses. Due to extensive heterogeneity and multiple overlapping transcriptional programs in...
Reaction Time and Visual Memory in Connection with Alcohol Use in Schizophrenia and Schizoaffective Disorder.
Atiqul Haq Mazumder, Jennifer Barnett, Nina Lindberg, Minna Torniainen-Holm, Markku Lähteenvuo, Kaisla Lahdensuo, Martta Kerkelä, Jarmo Hietala, Erkki Tapio Isometsä, Olli Kampman, Tuula Kieseppä, Tuomas Jukuri, Katja Häkkinen, Erik Cederlöf, Willehard Haaki, Risto Kajanne, Asko Wegelius, Teemu Männynsalo, Jussi Niemi-Pynttäri, Kimmo Suokas, Jouko Lönnqvist, Solja Niemelä, Jari Tiihonen, Tiina Paunio, Aarno Palotie, Jaana Suvisaari, Juha Veijola
Jul 07, 2021
The purpose of this study was to explore the association between cognition and hazardous drinking and alcohol use disorder in schizophrenia and schizoaffective disorder. Cognition is more or less compromised in schizophrenia...
Published by: Brain sciences
Reaction Time and Visual Memory in Connection to Alcohol Use in Persons with Bipolar Disorder.
Atiqul Haq Mazumder, Jennifer Barnett, Erkki Tapio Isometsä, Nina Lindberg, Minna Torniainen-Holm, Markku Lähteenvuo, Kaisla Lahdensuo, Martta Kerkelä, Ari Ahola-Olli, Jarmo Hietala, Olli Kampman, Tuula Kieseppä, Tuomas Jukuri, Katja Häkkinen, Erik Cederlöf, Willehard Haaki, Risto Kajanne, Asko Wegelius, Teemu Männynsalo, Jussi Niemi-Pynttäri, Kimmo Suokas, Jouko Lönnqvist, Jari Tiihonen, Tiina Paunio, Seppo Juhani Vainio, Aarno Palotie, Solja Niemelä, Jaana Suvisaari, Juha Veijola
Oct 29, 2021
The purpose of this study was to explore the association of cognition with hazardous drinking and alcohol-related disorder in persons with bipolar disorder (BD). The study population included 1268 persons from Finland with...
Published by: Brain sciences
Erratum to
Valentina Proserpio, Andrea Piccolo, Liora Haim-Vilmovsky, Gozde Kar, Tapio Lönnberg, Valentine Svensson, Jhuma Pramanik, Kedar Nath Natarajan, Weichao Zhai, Xiuwei Zhang, Giacomo Donati, Melis Kayikci, Jurij Kotar, Andrew NJ McKenzie, Ruddy Montandon, Kylie R James, Daniel Fernandez-Ruiz, William R Heath, Ashraful Haque, Oliver Billker, Steven Woodhouse, Pietro Cicuta, Mario Nicodemi, Sarah A Teichmann
May 16, 2019
Reaction Time and Visual Memory in Connection to Alcohol Use in Persons with Bipolar Disorder
Atiqul Haq Mazumder, Jennifer Barnett, Erkki Tapio Isometsä, Nina Lindberg, Minna Torniainen-Holm, Markku Lähteenvuo, Kaisla Lahdensuo, Martta Kerkelä, Ari Ahola-Olli, Jarmo Hietala, Olli Kampman, Tuula Kieseppä, Tuomas Jukuri, Katja Häkkinen, Erik Cederlöf, Willehard Haaki, Risto Kajanne, Asko Wegelius, Teemu Männynsalo, Jussi Niemi-Pynttäri, Kimmo Suokas, Jouko Lönnqvist, Jari Tiihonen, Tiina Paunio, Seppo Juhani Vainio, Aarno Palotie, Solja Niemelä, Jaana Suvisaari, Juha Veijola
Sep 01, 2021
The purpose of this study was to explore the association of cognition with hazardous drinking and alcohol-related disorder in persons with bipolar disorder (BD). The study population included 1268 persons from Finland with...
Artificial intelligence in nursing
Charlene Esteban Ronquillo, Laura‐Maria Peltonen, Lisiane Pruinelli, Charlene H. Chu, Suzanne Bakken, Ana Beduschi, Kenrick Cato, Nicholas Hardiker, Alain Junger, Martin Michalowski, Rune Nyrup, Samira Rahimi, Donald Nigel Reed, Tapio Salakoski, Sanna Salanterä, Nancy Walton, Patrick Weber, Thomas Wiegand, Maxim Topaz
May 20, 2021
GUIDELINES AND CONSENSUS STATEMENTS Health Services Research information technology leadership Management nurse roles Policy Politics technology workforce issues
Published by: Journal of advanced nursing
Reaction Time and Visual Memory in Connection to Hazardous Drinking Polygenic Scores in Schizophrenia, Schizoaffective Disorder and Bipolar Disorder.
Atiqul Haq Mazumder, Jennifer Barnett, Erkki Tapio Isometsä, Nina Lindberg, Minna Torniainen-Holm, Markku Lähteenvuo, Kaisla Lahdensuo, Martta Kerkelä, Ari Ahola-Olli, Jarmo Hietala, Olli Kampman, Tuula Kieseppä, Tuomas Jukuri, Katja Häkkinen, Erik Cederlöf, Willehard Haaki, Risto Kajanne, Asko Wegelius, Teemu Männynsalo, Jussi Niemi-Pynttäri, Kimmo Suokas, Jouko Lönnqvist, Jari Tiihonen, Tiina Paunio, Seppo Juhani Vainio, Aarno Palotie, Solja Niemelä, Jaana Suvisaari, Juha Veijola
Jan 07, 2022
The purpose of this study was to explore the association of cognition with hazardous drinking Polygenic Scores (PGS) in 2649 schizophrenia, 558 schizoaffective disorder, and 1125 bipolar disorder patients in Finland. Hazardous...
Reaction Time and Visual Memory in Connection to Alcohol Use in Persons with Bipolar Disorder.
Atiqul Haq Mazumder, Jennifer Barnett, Erkki Tapio Isometsä, Nina Lindberg, Minna Torniainen-Holm, Markku Lähteenvuo, Kaisla Lahdensuo, Martta Kerkelä, Ari Ahola-Olli, Jarmo Hietala, Olli Kampman, Tuula Kieseppä, Tuomas Jukuri, Katja Häkkinen, Erik Cederlöf, Willehard Haaki, Risto Kajanne, Asko Wegelius, Teemu Männynsalo, Jussi Niemi-Pynttäri, Kimmo Suokas, Jouko Lönnqvist, Jari Tiihonen, Tiina Paunio, Seppo Juhani Vainio, Aarno Palotie, Solja Niemelä, Jaana Suvisaari, Juha Veijola
Nov 22, 2021
The purpose of this study was to explore the association of cognition with hazardous drinking and alcohol-related disorder in persons with bipolar disorder (BD). The study population included 1268 persons from Finland with...
Reaction Time and Visual Memory in Connection to Hazardous Drinking Polygenic Scores in Schizophrenia, Schizoaffective Disorder and Bipolar Disorder.
Atiqul Haq Mazumder, Jennifer Barnett, Erkki Tapio Isometsä, Nina Lindberg, Minna Torniainen-Holm, Markku Lähteenvuo, Kaisla Lahdensuo, Martta Kerkelä, Ari Ahola-Olli, Jarmo Hietala, Olli Kampman, Tuula Kieseppä, Tuomas Jukuri, Katja Häkkinen, Erik Cederlöf, Willehard Haaki, Risto Kajanne, Asko Wegelius, Teemu Männynsalo, Jussi Niemi-Pynttäri, Kimmo Suokas, Jouko Lönnqvist, Jari Tiihonen, Tiina Paunio, Seppo Juhani Vainio, Aarno Palotie, Solja Niemelä, Jaana Suvisaari, Juha Veijola
Oct 29, 2021
The purpose of this study was to explore the association of cognition with hazardous drinking Polygenic Scores (PGS) in 2649 schizophrenia, 558 schizoaffective disorder, and 1125 bipolar disorder patients in Finland. Hazardous...
Reaction Time and Visual Memory in Connection with Alcohol Use in Schizophrenia and Schizoaffective Disorder.
Atiqul Haq Mazumder, Jennifer Barnett, Nina Lindberg, Minna Torniainen-Holm, Markku Lähteenvuo, Kaisla Lahdensuo, Martta Kerkelä, Jarmo Hietala, Erkki Tapio Isometsä, Olli Kampman, Tuula Kieseppä, Tuomas Jukuri, Katja Häkkinen, Erik Cederlöf, Willehard Haaki, Risto Kajanne, Asko Wegelius, Teemu Männynsalo, Jussi Niemi-Pynttäri, Kimmo Suokas, Jouko Lönnqvist, Solja Niemelä, Jari Tiihonen, Tiina Paunio, Aarno Palotie, Jaana Suvisaari, Juha Veijola
Aug 16, 2021
The purpose of this study was to explore the association between cognition and hazardous drinking and alcohol use disorder in schizophrenia and schizoaffective disorder. Cognition is more or less compromised in schizophrenia...
A global analysis of the impact of COVID-19 stay-at-home restrictions on crime.
Amy E Nivette, Renee Zahnow, Raul Aguilar, Andri Ahven, Shai Amram, Barak Ariel, María José Arosemena Burbano, Roberta Astolfi, Dirk Baier, Hyung-Min Bark, Joris EH Beijers, Marcelo Bergman, Gregory Breetzke, I Alberto Concha-Eastman, Sophie Curtis-Ham, Ryan Davenport, Carlos Díaz, Diego Fleitas, Manne Gerell, Kwang-Ho Jang, Juha Kääriäinen, Tapio Lappi-Seppälä, Woon-Sik Lim, Rosa Loureiro Revilla, Lorraine Mazerolle, Gorazd Meško, Noemí Pereda, Maria FT Peres, Rubén Poblete-Cazenave, Simon Rose, Robert Svensson, Nico Trajtenberg, Tanja van der Lippe, Joran Veldkamp, Carlos J Vilalta Perdomo, Manuel P Eisner
Jun 22, 2021
Prostate cancer risk regions at 8q24 and 17q24 are differentially associated with somatic TMPRSS2
Manuel Luedeke, Antje E Rinckleb, Liesel M Fitzgerald, Milan S Geybels, Johanna Schleutker, Rosalind A Eeles, Manuel R Teixeira, Lisa Cannon-Albright, Elaine A Ostrander, Steffen Weikert, Kathleen Herkommer, Tiina Wahlfors, Tapio Visakorpi, Katri A Leinonen, Teuvo LJ Tammela, Colin S Cooper, Zsofia Kote-Jarai, Sandra Edwards, Chee L Goh, Frank McCarthy, Chris Parker, Penny Flohr, Paula Paulo, Carmen Jerónimo, Rui Henrique, Hans Krause, Sven Wach, Verena Lieb, Tilman T Rau, Walther Vogel, Rainer Kuefer, Matthias D Hofer, Sven Perner, Mark A Rubin, Archana M Agarwal, Doug F Easton, Ali Amin Al Olama, Sara Benlloch, PRACTICAL Consortium, Josef Hoegel, Janet L Stanford, Christiane Maier
Dec 13, 2016
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