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Evaluation of a Pseudotyped Virus Neutralisation Test for the Measurement of Equine Influenza Virus-Neutralising Antibody Responses Induced by Vaccination and Infection.
Rebecca Kinsley, Stéphane Pronost, Manuelle De Bock, Nigel Temperton, Janet M Daly, Romain Paillot, Simon Scott
Aug 24, 2020
Equine influenza is a major respiratory disease of horses that is largely controlled by vaccination in some equine populations. Virus-neutralising antibodies, the mainstay of the protective immune response, are problematic in...
The Bicyclic Form of galacto-Noeurostegine Is a Potent Inhibitor of β-Galactocerebrosidase.
Competitive inhibitors of galactocerebrosidase (GALC) could be candidates for pharmacological chaperone therapy of patients with Krabbe disease. The known and selective nortropane-type iminosugar galacto-noeurostegine has been...
Is subarctic forest advance able to keep pace with climate change?
W Gareth Rees, Annika Hofgaard, Stéphane Boudreau, David M Cairns, Karen Harper, Steven Mamet, Ingrid Mathisen, Zuzanna Swirad, Olga Tutubalina
Apr 06, 2020
Producing molecular biology reagents without purification
Sanchita Bhadra, Vylan Nguyen, Jose-Angel Torres, Shaunak Kar, Stéphane Fadanka, Chiara Gandini, Harry Akligoh, Inyup Paik, Andre C. Maranhao, Jenny Molloy, Andrew D. Ellington
Jun 04, 2021
The role of dopamine in the brain - lessons learned from Parkinson's disease.
David Meder, Damian Marc Herz, James Benedict Rowe, Stéphane Lehéricy, Hartwig Roman Siebner
Dec 21, 2018
Parkinson's disease causes a characteristic combination of motor symptoms due to progressive neurodegeneration of dopaminergic neurons in the substantia nigra pars compacta. The core impairment of dopaminergic neurotransmission...
Muscle strength is associated with COVID-19 hospitalization in adults 50 years of age or older.
Boris Cheval, Stefan Sieber, Silvio Maltagliati, Grégoire P Millet, Tomáš Formánek, Aïna Chalabaev, Stéphane Cullati, Matthieu P Boisgontier
Aug 11, 2021
Supply chains create global benefits from improved vaccine accessibility.
Daoping Wang, Ottar N Bjørnstad, Tianyang Lei, Yida Sun, Jingwen Huo, Qi Hao, Zhao Zeng, Shupeng Zhu, Stéphane Hallegatte, Ruiyun Li, Dabo Guan, Nils C Stenseth
Apr 17, 2023
Ensuring a more equitable distribution of vaccines worldwide is an effective strategy to control global pandemics and support economic recovery. We analyze the socioeconomic effects - defined as health gains, lockdown-easing...
Published by: Nature Communications
How to Manage Incompleteness of Nutritional Food Sources?
Patrice Buche, Julien Cufi, Stéphane Dervaux, Juliette Dibie, Liliana Ibanescu, Alrick Oudot, Magalie Weber
Oct 01, 2021
In order to correctly assess the nutritional quality of a raw or manufactured food product, the first step is to obtain the associated nutritional values. Food composition databases (FCDBs) managed at national level provide...
Published by: IGI Global Scientific Publishing
Environmental proxies of antigen exposure explain variation in immune investment better than indices of pace of life.
Nicholas PC Horrocks, Arne Hegemann, Stéphane Ostrowski, Henry Ndithia, Mohammed Shobrak, Joseph B Williams, Kevin D Matson, BI Tieleman
Mar 20, 2015
COVIDiSTRESS Global Survey dataset on psychological and behavioural consequences of the COVID-19 outbreak.
Intense bone fluorescence reveals hidden patterns in pumpkin toadlets.
Sandra Goutte, Matthew J Mason, Marta M Antoniazzi, Carlos Jared, Didier Merle, Lilian Cazes, Luís Felipe Toledo, Hanane El-Hafci, Stéphane Pallu, Hugues Portier, Stefan Schramm, Pierre Gueriau, Mathieu Thoury
Apr 25, 2019
The phenomenon of fluorescence can be used by animals to change effective colouration or patterning, potentially to serve functions including intra- and interspecific signalling. Initially believed to be restricted to marine...
Mapping lightning in the sky with a mini array
Martin Füllekrug, Zhongjian Liu, Kuang Koh, Andrew Mezentsev, Stéphane Pedeboy, Serge Soula, Sven Erik Enno, Jacqueline Sugier, Michael J. Rycroft
Oct 16, 2016
Mini arrays are commonly used for infrasonic and seismic studies. Here we report for the first time the detection and mapping of distant lightning discharges in the sky with a mini array. The array has a baseline to...
The peroxisomal fatty acid transporter ABCD1/PMP-4 is required in the C. elegans hypodermis for axonal maintenance
Andrea Coppa, Sanjib Guha, Stéphane Fourcade, Janani Parameswaran, Montserrat Ruiz, Ann B Moser, Agatha Schlüter, Michael P Murphy, Jose Miguel Lizcano, Antonio Miranda-Vizuete, Esther Dalfó, Aurora Pujol
Feb 18, 2020
Adrenoleukodystrophy is a neurometabolic disorder caused by a defective peroxisomal ABCD1 transporter of very long-chain fatty acids (VLCFAs). Its pathogenesis is incompletely understood. Here we characterize a nematode model of...
Axonal degeneration Hypodermis Lipid Droplets Mitochondria redox imbalance Peroxisomes X-linked adrenoleukodystrophy ATP Binding Cassette Transporter Subfamily D Member 1 ATP-Binding Cassette Transporters Adrenoleukodystrophy Animals Caenorhabditis elegans Fatty Acids Mice Mice Knockout Subcutaneous Tissue
Disease-associated XMRV sequences are consistent with laboratory contamination.
Stéphane Hué, Eleanor R Gray, Astrid Gall, Aris Katzourakis, Choon Ping Tan, Charlotte J Houldcroft, Stuart McLaren, Deenan Pillay, Andrew Futreal, Jeremy A Garson, Oliver G Pybus, Paul Kellam, Greg J Towers
Oct 03, 2018
BACKGROUND: Xenotropic murine leukaemia viruses (MLV-X) are endogenous gammaretroviruses that infect cells from many species, including humans. Xenotropic murine leukaemia virus-related virus (XMRV) is a retrovirus that has been...
Adaptive Trade-offs Towards the Last Glacial Maximum in North-Western Europe
Luc Moreau, Christelle Draily, Jean-Marie Cordy, Katherine Boyle, Michael Buckley, Erik Gjesfjeld, Peter Filzmoser, Valentina Borgia, Sally A. Gibson, Jason Day, Robert Beyer, Andrea Manica, Marc Vander Linden, Marjorie de Grooth, Stéphane Pirson
Apr 16, 2021
Abstract: The impact of deteriorating climatic conditions on variability in the archaeological record towards the Last Glacial Maximum (LGM) remains uncertain. Partly as a result of poor-quality data, previous studies on Upper...
Mapping lightning in the sky with a mini array
Martin Füllekrug, Zhongjian Liu, Kuang Koh, Andrew Mezentsev, Stéphane Pedeboy, Serge Soula, Sven Erik Enno, Jacqueline Sugier, Michael J. Rycroft
Oct 16, 2016
Mini arrays are commonly used for infrasonic and seismic studies. Here we report for the first time the detection and mapping of distant lightning discharges in the sky with a mini array. The array has a baseline to...
A randomized, double-blind trial of triheptanoin for drug-resistant epilepsy in glucose transporter 1 deficiency syndrome.
Pasquale Striano, Stéphane Auvin, Abigail Collins, Rita Horvath, Ingrid E Scheffer, Michal Tzadok, Ian Miller, Mary Kay Koenig, Adrian Lacy, Ronald Davis, Angela Garcia-Cazorla, Russell P Saneto, Melanie Brandabur, Susan Blair, Tony Koutsoukos, Darryl De Vivo
May 21, 2022
diet treatment Drug Resistance Epilepsy glucose transporter 1 deficiency syndrome triheptanoin Adolescent Adult Anticonvulsants Carbohydrate Metabolism Inborn Errors Child Double-Blind Method Drug Resistant Epilepsy Drug Therapy Combination Epilepsy Absence Glucose Transporter Type 1 Humans Monosaccharide Transport Proteins Seizures Treatment Outcome Triglycerides
Gingival fibroblasts protect against experimental abdominal aortic aneurysm development and rupture through tissue inhibitor of metalloproteinase-1 production.
Andreas Giraud, Lynda Zeboudj, Marie Vandestienne, Jérémie Joffre, Bruno Esposito, Stéphane Potteaux, José Vilar, Daniela Cabuzu, Johannes Kluwe, Sylvie Seguier, Alain Tedgui, Ziad Mallat, Antoine Lafont, Hafid Ait-Oufella
Apr 09, 2019
AIMS: Abdominal aortic aneurysm (AAA), frequently diagnosed in old patients, is characterized by chronic inflammation, vascular cell apoptosis and metalloproteinase-mediated extracellular matrix destruction. Despite improvement...
abdominal aortic aneurysm Cell therapy Gingival fibroblasts Metalloproteases Remodelling Angiotensin II Animals Aorta Abdominal Aortic Aneurysm Abdominal Aortic Rupture Disease Models Animal Extracellular Matrix FIBROBLASTS Gingiva Mice Inbred C57BL Mice Knockout Protective Agents Tissue Inhibitor of Metalloproteinase-1 Transforming Growth Factor beta
Controlling All-Optical Helicity-Dependent Switching in Engineered Rare-Earth Free Synthetic Ferrimagnets.
Jung-Wei Liao, Pierre Vallobra, Liam O'Brien, Unai Atxitia, Victor Raposo, Dorothée Petit, Tarun Vemulkar, Gregory Malinowski, Michel Hehn, Eduardo Martínez, Stéphane Mangin, Russell P Cowburn
Jan 29, 2020
All-optical helicity-dependent switching in ferromagnetic layers has revealed an unprecedented route to manipulate magnetic configurations by circularly polarized femtosecond laser pulses. In this work, rare-earth free synthetic...
Extensive unusual lesions on a large number of immersed human victims found to be from cookiecutter sharks (Isistius spp.)
Agathe Ribéreau-Gayon, Carolyn Rando, Yves Schuliar, Stéphane Chapenoire, Enrico R Crema, Julien Claes, Bernard Seret, Vincent Maleret, Ruth M Morgan
Oct 26, 2016
Producing molecular biology reagents without purification.
Sanchita Bhadra, Vylan Nguyen, Jose-Angel Torres, Shaunak Kar, Stéphane Fadanka, Chiara Gandini, Harry Akligoh, Inyup Paik, Andre C Maranhao, Jenny Molloy, Andrew D Ellington
Jul 02, 2021
We recently developed 'cellular' reagents-lyophilized bacteria overexpressing proteins of interest-that can replace commercial pure enzymes in typical diagnostic and molecular biology reactions. To make cellular reagent...
covid-19 COVID-19 Testing Cameroon Diagnostic Tests Routine Escherichia coli Gene Expression Geobacillus stearothermophilus Ghana Humans Indicators and Reagents Molecular Diagnostic Techniques Plasmids Real-Time Polymerase Chain Reaction Recombinant Proteins SARS-CoV-2 synthetic biology Transformation Bacterial United Kingdom
Identification of shared genetic variants between schizophrenia and lung cancer.
Verena Zuber, Erik G Jönsson, Oleksandr Frei, Aree Witoelar, Wesley K Thompson, Andrew J Schork, Francesco Bettella, Yunpeng Wang, Srdjan Djurovic, Olav B Smeland, Ingrid Dieset, Ayman H Fanous, Rahul S Desikan, Sébastien Küry, Stéphane Bézieau, Anders M Dale, Ian G Mills, Ole A Andreassen
Mar 20, 2018
Epidemiology studies suggest associations between schizophrenia and cancer. However, the underlying genetic mechanisms are not well understood, and difficult to identify from epidemiological data. We investigated if there is a...
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