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Results: 51
Patient focused registries can improve health, care, and science.
Eugene C Nelson, Mary Dixon-Woods, Paul B Batalden, Karen Homa, Aricca D Van Citters, Tamara S Morgan, Elena Eftimovska, Elliott S Fisher, John Ovretveit, Wade Harrison, Cristin Lind, Staffan Lindblad
Jul 05, 2016
Punnett squares and hybrid crosses
Abstract The rapid reception of Gregor Mendel's paper ‘Experiments on plant hybrids’ (1866) in the early decades of the twentieth century remains poorly understood. We will suggest that this...
Tenfold Way for Quadratic Lindbladians.
We uncover a topological classification applicable to open fermionic systems governed by a general class of Lindblad master equations. These "quadratic Lindbladians" can be captured by a non-Hermitian single-particle matrix...
Current state of high-fidelity multimodal monitoring in traumatic brain injury.
Prognostic performance of computerized tomography scoring systems in civilian penetrating traumatic brain injury
Matias Lindfors, Caroline Lindblad, David W Nelson, Bo-Michael Bellander, Jari Siironen, Rahul Raj, Eric P Thelin
Oct 27, 2020
Expression of a carotenoid‐modifying gene and evolution of red coloration in weaverbirds (Ploceidae)
Red carotenoid colours in birds are widely assumed to be sexually selected quality indicators, but this rests on a very incomplete understanding of genetic mechanisms and honesty-mediating costs. Recent progress was made by the...
Of elephants and errors
What is it to make an error in the identification of a named taxonomic group? In this article we argue that the conditions for being in error about the identity of taxonomic groups through their names have a history, and that...
Secondary cell wall patterning-connecting the dots, pits and helices.
Huizhen Xu, Alessandro Giannetti, Yuki Sugiyama, Wenna Zheng, René Schneider, Yoichiro Watanabe, Yoshihisa Oda, Staffan Persson
Jan 04, 2023
Assessment of Platelet Function in Traumatic Brain Injury-A Retrospective Observational Study in the Neuro-Critical Care Setting.
Caroline Lindblad, Eric Peter Thelin, Michael Nekludov, Arvid Frostell, David W Nelson, Mikael Svensson, Bo-Michael Bellander
Jun 28, 2018
BACKGROUND: Despite seemingly functional coagulation, hemorrhagic lesion progression is a common and devastating condition following traumatic brain injury (TBI), stressing the need for new diagnostic techniques. Multiple...
Evolution of CYP2J19, a gene involved in colour vision and red coloration in birds
Background: Exaggerated signals, such as brilliant colours, are usually assumed to evolve through antagonistic coevolution between senders and receivers, but the underlying genetic mechanisms are rarely known. Here we explore a...
Animals Birds Cytochrome P-450 Enzyme System Pigmentation evolution Molecular Species Specificity Conserved Sequence Genome Color Vision Genetic Loci Genetic Pleiotropy
Published by: BMC evolutionary biology
Secondary cell wall patterning-connecting the dots, pits and helices.
Huizhen Xu, Alessandro Giannetti, Yuki Sugiyama, Wenna Zheng, René Schneider, Yoichiro Watanabe, Yoshihisa Oda, Staffan Persson
Jun 07, 2022
Dextran 500 Improves Recovery of Inflammatory Markers
Susan Giorgi-Coll, Eric Peter Thelin, Caroline Lindblad, Tamara Tajsic, Keri LH Carpenter, Peter JA Hutchinson, Adel Helmy
Jul 18, 2019
Systemic inflammation alters the neuroinflammatory response
Philipp Lassarén, Caroline Lindblad, Arvid Frostell, Keri LH Carpenter, Mathew R Guilfoyle, Peter JA Hutchinson, Adel Helmy, Eric Peter Thelin
Nov 22, 2021
BACKGROUND: Neuroinflammation following traumatic brain injury (TBI) has been shown to be associated with secondary injury development; however, how systemic inflammatory mediators affect this is not fully understood. The aim of...
Alpha-Synuclein Expression in the Oligodendrocyte Lineage
Mehdi Djelloul, Staffan Holmqvist, Antonio Boza-Serrano, Carla Azevedo, Maggie S Yeung, Stefano Goldwurm, Jonas Frisén, Tomas Deierborg, Laurent Roybon
Jun 01, 2020
In this study, we sought evidence for alpha-synuclein (ASYN) expression in oligodendrocytes, as a possible endogenous source of ASYN to explain its presence in glial inclusions found in multiple system atrophy (MSA) and...
Human Astrocytes Transfer Aggregated Alpha-Synuclein via Tunneling Nanotubes.
Jinar Rostami, Staffan Holmqvist, Veronica Lindström, Jessica Sigvardson, Gunilla T Westermark, Martin Ingelsson, Joakim Bergström, Laurent Roybon, Anna Erlandsson
Jun 01, 2020
Many lines of evidence suggest that the Parkinson's disease (PD)-related protein α-synuclein (α-SYN) can propagate from cell to cell in a prion-like manner. However, the cellular mechanisms behind the spreading remain elusive....
Systemic inflammation alters the neuroinflammatory response
Philipp Lassarén, Caroline Lindblad, Arvid Frostell, Keri L H Carpenter, Mathew R Guilfoyle, Peter J A Hutchinson, Adel Helmy, Eric Peter Thelin
Oct 28, 2021
Background
Neuroinflammation following traumatic brain injury (TBI) has been shown to be associated with secondary injury development; however, how systemic inflammatory mediators affect this is not fully understood. The...
Published by: Journal of neuroinflammation
Novel AAV-based rat model of forebrain synucleinopathy shows extensive pathologies and progressive loss of cholinergic interneurons.
Synucleinopathies, characterized by intracellular aggregation of α-synuclein protein, share a number of features in pathology and disease progression. However, the vulnerable cell population differs significantly between the...
Animals Animals Newborn Axons Cell Nucleus Cholinergic Neurons Dependovirus Disease Models Animal Disease Progression Dopamine Agonists Exploratory Behavior Female Genetic Vectors Humans Interneurons Lewy Body Disease Microglia Motor Activity Neostriatum Phenotype Pregnancy Prosencephalon Protein Transport Rats Rats Sprague-Dawley Synapses ALPHA-SYNUCLEIN
Cycles and circulation
Nick Hopwood, Staffan Müller-Wille, Janet Browne, Christiane Groeben, Shigehisa Kuriyama, Maaike van der Lugt, Guido Giglioni, Lynn K Nyhart, Hans-Jörg Rheinberger, Ariane Dröscher, Warwick Anderson, Peder Anker, Mathias Grote, Lucy van de Wiel
Aug 12, 2021
We invite systematic consideration of the metaphors of cycles and circulation as a long-term theme in the history of the life and environmental sciences and medicine. Ubiquitous in ancient religious and philosophical traditions...
recycling Diagrams Metaphors Life cycles Circles Canonical icons Biology History Ancient History Medieval History 15th Century History 16th Century History 17th Century History 18th century History 19th Century History 20th Century History 21st Century history of medicine Philosophy
Published by: History and philosophy of the life sciences
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