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Results: 139
Incorporating tumour pathology information into breast cancer risk prediction algorithms.
Nasim Mavaddat, Timothy R Rebbeck, Sunil R Lakhani, Douglas F Easton, Antonis C Antoniou
Jun 17, 2011
Basal-like grade III invasive ductal carcinoma of the breast
Laura G Fulford, Jorge S Reis-Filho, Ken Ryder, Chris Jones, Cheryl E Gillett, Andrew Hanby, Douglas Easton, Sunil R Lakhani
Jun 17, 2011
The mutational landscape of melanoma brain metastases presenting as the first visceral site of recurrence.
Roy Rabbie, Peter Ferguson, Kim Wong, Dominique-Laurent Couturier, Una Moran, Clinton Turner, Patrick Emanuel, Kerstin Haas, Jodi M Saunus, Morgan R Davidson, Sunil R Lakhani, Brindha Shivalingam, Georgina V Long, Christine Parkinson, Iman Osman, Richard A Scolyer, Pippa Corrie, David J Adams
Oct 07, 2021
Survival and disease characteristics of de novo versus recurrent metastatic breast cancer in a cohort of young patients
Hayley S. McKenzie, Tom Maishman, Peter Simmonds, Lorraine Durcan, Diana Eccles, Ellen Copson, Douglas G. Altman, Louise Jones, Gareth Evans, Alastair M. Thompson, Paul Pharaoh, Andrew Hanby, Sunil Lakhani, Ros Eeles, Fiona J. Gilbert, Hisham Hamed, Shirley Hodgson
Mar 31, 2021
Abstract: Background: It is not clear how the pathology, presentation and outcome for patients who present with de novo metastatic breast cancer (dnMBC) compare with those who later develop distant metastases. DnMBC is uncommon...
The mutational landscape of melanoma brain metastases presenting as the first visceral site of recurrence
Roy Rabbie, Peter Ferguson, Kim Wong, Dominique-Laurent Couturier, Una Moran, Clinton Turner, Patrick Emanuel, Kerstin Haas, Jodi M. Saunus, Morgan R. Davidson, Sunil R. Lakhani, Brindha Shivalingam, Georgina V. Long, Christine Parkinson, Iman Osman, Richard A. Scolyer, Pippa Corrie, David J. Adams
Jan 05, 2021
Registry Studies Use Inconsistent Methods to Account for Patients Lost to Follow-up, and Rates of Patients LTFU Are High.
PURPOSE: To determine methods described in the literature to account for patients lost to follow-up (LTFU) in registry studies and whether rates of patient LTFU are within acceptable margins. METHODS: A scoping review, where a...
An Energy-Efficient Multi-Channel Design for Distributed Wireless Sensor Networks
Sunil Kumar
Jan 01, 2023
This article discusses the importance of designing an efficient medium access control (MAC) protocol for wireless sensor networks (WSNs) to optimize energy consumption at the data link layer while transmitting high traffic...
Grid & High Performance Computing Computer Science and Information Technology High Performance Computing
Published by: IGI Global Scientific Publishing
Electrochemical immunosensor for tumor necrosis factor-alpha detection in undiluted serum
An immunosensor for the sensitive detection and estimation of tumor necrosis factor-alpha (TNF-α) in undiluted serum has been developed via an electrochemical enzyme-linked immunosorbent assay (ELISA) process. Electrochemical...
Electrochemical ELISA Protein Biosensing in Undiluted Serum Using a Polypyrrole-Based Platform
An electrochemical enzyme-linked immunosorbent assay (ELISA) biosensor platform using electrochemically prepared ~11 nm thick carboxylic functionalized popypyrrole film has been developed for bio-analyte measurement in undiluted...
biomarker Biosensor Carboxyl polypyrrole Differential pulse voltammetry Electrochemical ELISA Polymeric alkaline phosphatase TNF-α /dk/atira/pure/subjectarea/asjc/1600/1602 name=Analytical Chemistry /dk/atira/pure/subjectarea/asjc/1300/1303 name=Biochemistry /dk/atira/pure/subjectarea/asjc/3100/3107 name=Atomic and Molecular Physics, and Optics /dk/atira/pure/subjectarea/asjc/3100/3105 name=Instrumentation /dk/atira/pure/subjectarea/asjc/2200/2208 name=Electrical and Electronic Engineering
Avoiding iatrogenic injury during portal placement in hip arthroscopy.
Hip arthroscopy has gained immense popularity in the treatment of
many intra and extra-articular pathologies in and around the hip joint.
The anterolateral portal is the most common portal used to establish
access at arthroscopy...
IMPROVING SOFTWARE PROJECTS WITH CLOUD COMPUTING
SUNIL MADDIPATLA
Jan 01, 0001
As organizations are experiencing regular unforgiving financial conditions, ideas, for example, outsourcing, deft and lean administration, change administration and cost diminishment are always increasing more consideration....
Cloud Cloud Computing VPC's VPN public private internet and intranet. Human Resources Management Interpersonal and Small Group Communication Management Information Systems Management Sciences and Quantitative Methods
Published by: Harrisburg University of Science and Technology
Electrochemical immunosensor for tumor necrosis factor-alpha detection in undiluted serum
An immunosensor for the sensitive detection and estimation of tumor necrosis factor-alpha (TNF-α) in undiluted serum has been developed via an electrochemical enzyme-linked immunosorbent assay (ELISA) process. Electrochemical...
Management of Stiffness following Total Knee Arthroplasty
INTRODUCTION: Stiffness following total knee arthroplasty (TKA) is a challenging complication and can result in a poor functional outcome. There is considerable debate concerning the definition, work-up, and optimal management...
Engineering serendipity
Research Summary: We investigate how knowledge similarity between two individuals is systematically related to the likelihood that a serendipitous encounter results in knowledge production. We conduct a field experiment at a...
Capacitive malaria aptasensor using Plasmodium falciparum glutamate dehydrogenase as target antigen in undiluted human serum
A capacitive aptasensor for detecting the malaria biomarker, Plasmodium falciparum glutamate dehydrogenase (PfGDH), directly in human serum samples developed. A thiolated ssDNA aptamer (NG3) that binds specifically to PfGDH...
Non-coding RNAs underlie genetic predisposition to breast cancer
Mahdi Moradi Marjaneh, Jonathan Beesley, Tracy A. O’Mara, Pamela Mukhopadhyay, Lambros T. Koufariotis, Stephen Kazakoff, Nehal Hussein, Laura Fachal, Nenad Bartonicek, Kristine M. Hillman, Susanne Kaufmann, Haran Sivakumaran, Chanel E. Smart, Amy E. McCart Reed, Kaltin Ferguson, Jodi M. Saunus, Sunil R. Lakhani, Daniel R. Barnes, Antonis C. Antoniou, Marcel E. Dinger, Nicola Waddell, Douglas F. Easton, Alison M. Dunning, Georgia Chenevix-Trench, Stacey L. Edwards, Juliet D. French
Jun 06, 2020
Pathogenesis and contemporary diagnoses for lateral hip pain
PURPOSE: Recent advances in diagnostic imaging techniques and soft tissue endoscopy now allow for precise diagnosis and management of extra-articular hip pathology. The aim of this scoping review is to present an evidence-based...
Personalized Mastery-Based Learning Ecosystem
Children differ greatly in what they know and are ready to learn when they enter school. However, when their individual needs are assessed and addressed, even very young children can learn and can greatly surpass grade-level...
K-12 Education Education Learning Assessment and Measurement Social Sciences and Humanities Government and Law
Published by: IGI Global Scientific Publishing
Electrochemical ELISA-based platform for bladder cancer protein biomarker detection in urine
A novel fluidic-based electrochemical ELISA platform is descried for estimation of the bladder cancer protein markers nuclear mitotic apparatus protein 1 (NUMA1) and complement factor H-related 1 (CFHR1). The platform uses an...
Electrochemical ELISA Protein Biosensing in Undiluted Serum Using a Polypyrrole-Based Platform
An electrochemical enzyme-linked immunosorbent assay (ELISA) biosensor platform using electrochemically prepared ~11 nm thick carboxylic functionalized popypyrrole film has been developed for bio-analyte measurement in undiluted...
biomarker Biosensor Carboxyl polypyrrole Differential pulse voltammetry Electrochemical ELISA Polymeric alkaline phosphatase TNF-α /dk/atira/pure/subjectarea/asjc/1600/1602 name=Analytical Chemistry /dk/atira/pure/subjectarea/asjc/1300/1303 name=Biochemistry /dk/atira/pure/subjectarea/asjc/3100/3107 name=Atomic and Molecular Physics, and Optics /dk/atira/pure/subjectarea/asjc/3100/3105 name=Instrumentation /dk/atira/pure/subjectarea/asjc/2200/2208 name=Electrical and Electronic Engineering
Electrochemical ELISA-based platform for bladder cancer protein biomarker detection in urine
A novel fluidic-based electrochemical ELISA platform is descried for estimation of the bladder cancer protein markers nuclear mitotic apparatus protein 1 (NUMA1) and complement factor H-related 1 (CFHR1). The platform uses an...
Proteogenomic analysis of Inhibitor of Differentiation 4 (ID4) in basal-like breast cancer.
Laura A Baker, Holly Holliday, Daniel Roden, Christoph Krisp, Sunny Z Wu, Simon Junankar, Aurelien A Serandour, Hisham Mohammed, Radhika Nair, Geetha Sankaranarayanan, Andrew MK Law, Andrea McFarland, Peter T Simpson, Sunil Lakhani, Eoin Dodson, Christina Selinger, Lyndal Anderson, Goli Samimi, Neville F Hacker, Elgene Lim, Christopher J Ormandy, Matthew J Naylor, Kaylene Simpson, Iva Nikolic, Sandra O'Toole, Warren Kaplan, Mark J Cowley, Jason S Carroll, Mark Molloy, Alexander Swarbrick
Aug 21, 2020
BACKGROUND: Basal-like breast cancer (BLBC) is a poorly characterised, heterogeneous disease. Patients are diagnosed with aggressive, high-grade tumours and often relapse with chemotherapy resistance. Detailed understanding of...
Breast Cancer DNA Damage Helix-loop-helix Transcription factor Animals Apoptosis Breast Neoplasms Carcinoma Basal Cell Cell Differentiation Cell Line Tumor Cell Proliferation Chromatin DNA Damage Female Heterografts Humans Inhibitor of Differentiation Proteins Mice Mice Inbred NOD Mice SCID Prognosis Proteogenomics Tumor Cells Cultured
Clinical Study of Fungal Granulomatous Diseases
Introduction: Fungal Granulomatous disease is characterised by presence of granulomas with multinucleated giant cells and palisiding histiocytes. Aspergillosis is the commonest fungal infection of the nose and sinuses....
Published by: IJHS Medical Association
Over one third of patients with symptomatic femoroacetabular impingement display femoral or acetabular version abnormalities.
Zaki Arshad, Henry David Maughan, Karadi Hari Sunil Kumar, Matthew Pettit, Arvind Arora, Vikas Khanduja
Aug 26, 2021
PURPOSE: The aim of this study was investigate the relationship between version and torsional abnormalities of the acetabulum, femur and tibia in patients with symptomatic FAI. METHODS: A systematic review was performed...
Does the Type of Sport Influence Morphology of the Hip? A Systematic Review.
BACKGROUND: Femoroacetabular impingement (FAI) has been extensively investigated and is strongly associated with athletic participation. PURPOSE: To assess (1) the prevalence of cam-type FAI across various sports; (2) whether...
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