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Abnormally abrupt transitions from sleep-to-wake in Huntington's disease sheep (Ovis aries) are revealed by automated analysis of sleep/wake transition dynamics.
Sleep disturbance is a common and disruptive symptom of neurodegenerative diseases such as Alzheimer's and Huntington's disease (HD). In HD patients, sleep fragmentation appears at an early stage of disease, although features of...
Characterizing Sleep Spindles in Sheep.
Sleep spindles are distinctive transient patterns of brain activity that typically occur during non-rapid eye movement (NREM) sleep in humans and other mammals. Thought to be important for the consolidation of learning, they may...
Abnormally abrupt transitions from sleep-to-wake in Huntington's disease sheep (Ovis aries) are revealed by automated analysis of sleep/wake transition dynamics.
Sleep disturbance is a common and disruptive symptom of neurodegenerative diseases such as Alzheimer's and Huntington's disease (HD). In HD patients, sleep fragmentation appears at an early stage of disease, although features of...
Published by: PLOS ONE
Wake-Promoting and EEG Spectral Effects of Modafinil After Acute or Chronic Administration in the R6/2 Mouse Model of Huntington's Disease.
EEG power Gamma oscillation Cognitive enhancer Delta rapid eye movement sleep theta Animals Disease Models Animal Dose-Response Relationship Drug Drug Administration Schedule Electroencephalography Huntington Disease Male Mice Mice Inbred C57BL Mice Transgenic Modafinil Sleep Stages Wakefulness Wakefulness-Promoting Agents
Semantic Technology and Anthropomorphism
A long-standing debate exists on whether robots need personality. With voice assistants (VAs) (i.e., Google Assistant and Apple's Siri) as the research context, this study employed the stimulus-organism-response (SOR) model and...
Published by: IGI Global Scientific Publishing
Infants' conceptual representations of meaningful verbal and nonverbal sounds.
Louah Sirri, Ernesto Guerra, Szilvia Linnert, Eleanor S Smith, Vincent Reid, Eugenio Parise
Jun 08, 2020
In adults, words are more effective than sounds at activating conceptual representations. We aimed to replicate these findings and extend them to infants. In a series of experiments using an eye tracker object recognition task...
How corporate social responsibility and sustainable development functions impact the workplace
/dk/atira/pure/sustainabledevelopmentgoals/sustainable_cities_and_communities name=SDG 11 - Sustainable Cities and Communities /dk/atira/pure/sustainabledevelopmentgoals/partnerships name=SDG 17 - Partnerships for the Goals /dk/atira/pure/sustainabledevelopmentgoals/responsible_consumption_and_production name=SDG 12 - Responsible Consumption and Production
Published by: International Labour Office
The Effect of Guselkumab on General Health State in Biologic-Naïve Patients with Active Psoriatic Arthritis Through Week 52 of the Phase 3, Randomized, Placebo-Controlled DISCOVER-2 Trial
Jeffrey R Curtis, Iain B McInnes, Proton Rahman, Dafna D Gladman, Feifei Yang, Steven Peterson, Prasheen Agarwal, Alexa P Kollmeier, Elizabeth C Hsia, Chenglong Han, Natalie J Shiff, May Shawi, William Tillett, Philip J Mease
Oct 01, 2022
INTRODUCTION: In DISCOVER-2, guselkumab, an interleukin-23 p19 subunit inhibitor, was efficacious in biologic-naïve psoriatic arthritis (PsA) patients. We report the effect of guselkumab on health-related quality of life...
How corporate social responsibility and sustainable development functions impact the workplace
/dk/atira/pure/sustainabledevelopmentgoals/sustainable_cities_and_communities name=SDG 11 - Sustainable Cities and Communities /dk/atira/pure/sustainabledevelopmentgoals/partnerships name=SDG 17 - Partnerships for the Goals /dk/atira/pure/sustainabledevelopmentgoals/responsible_consumption_and_production name=SDG 12 - Responsible Consumption and Production
Published by: International Labour Office
Effects of Brief Dry Cupping on Muscle Soreness in the Gastrocnemius Muscle and Flexibility of the Ankle
OBJECTIVES The purpose of this study was to analyze the effects of brief dry cupping on muscle soreness of the gastrocnemius muscle and range of motion (ROM) in the ankle. METHODS Thirty-six participants (age=29±10 yrs...
Published by: Digital Commons @ Texas A&M University-San Antonio
Factors influencing Raynaud condition score diary outcomes in systemic sclerosis
Objective. Raynaud phenomenon (RP) in systemic sclerosis (SSc) could be influenced by clinical phenotype, environmental factors (e.g., season), and personal factors (e.g., coping strategies and ill-health perceptions). We...
Clinical Trials outcome measures patient-reported outcomes Raynaud phenomenon systemic sclerosis Validation Studies /dk/atira/pure/subjectarea/asjc/2700/2745 name=Rheumatology /dk/atira/pure/subjectarea/asjc/2700/2723 name=Immunology and Allergy /dk/atira/pure/subjectarea/asjc/2400/2403 name=Immunology
Factors influencing Raynaud condition score diary outcomes in systemic sclerosis
Objective. Raynaud phenomenon (RP) in systemic sclerosis (SSc) could be influenced by clinical phenotype, environmental factors (e.g., season), and personal factors (e.g., coping strategies and ill-health perceptions). We...
Clinical Trials outcome measures patient-reported outcomes Raynaud phenomenon systemic sclerosis Validation Studies /dk/atira/pure/subjectarea/asjc/2700/2745 name=Rheumatology /dk/atira/pure/subjectarea/asjc/2700/2723 name=Immunology and Allergy /dk/atira/pure/subjectarea/asjc/2400/2403 name=Immunology
Autologous Chondrocyte Implantation and Mesenchymal Stem Cells for the Treatments of Chondral Defects of the Knee- A Systematic Review.
Filippo Migliorini, Alessandra Berton, Giuseppe Salvatore, Vincenzo Candela, Wasim Khan, Umile G Longo, Vincenzo Denaro
Feb 24, 2020
BACKGROUND: There is still a lack of consensus about the best treatment of chondral defects of the knee. We conducted a systematic PRISMA review to evaluate clinical outcomes of Autologous Chondrocyte Implantation (ACI) and...
The Effect of Guselkumab on General Health State in Biologic-Naïve Patients with Active Psoriatic Arthritis Through Week 52 of the Phase 3, Randomized, Placebo-Controlled DISCOVER-2 Trial
Jeffrey R Curtis, Iain B McInnes, Proton Rahman, Dafna D Gladman, Feifei Yang, Steven Peterson, Prasheen Agarwal, Alexa P Kollmeier, Elizabeth C Hsia, Chenglong Han, Natalie J Shiff, May Shawi, William Tillett, Philip J Mease
Oct 01, 2022
INTRODUCTION: In DISCOVER-2, guselkumab, an interleukin-23 p19 subunit inhibitor, was efficacious in biologic-naïve psoriatic arthritis (PsA) patients. We report the effect of guselkumab on health-related quality of life...
Effects of Brief Dry Cupping on Muscle Soreness in the Gastrocnemius Muscle and Flexibility of the Ankle
OBJECTIVES The purpose of this study was to analyze the effects of brief dry cupping on muscle soreness of the gastrocnemius muscle and range of motion (ROM) in the ankle. METHODS Thirty-six participants (age=29±10 yrs...
Published by: Digital Commons @ Texas A&M University-San Antonio
Health-related quality of life after traumatic brain injury
Daphne C Voormolen, Suzanne Polinder, Nicole von Steinbuechel, Yan Feng, Lindsay Wilson, Mark Oppe, Juanita A Haagsma, CENTER-TBI Participants and Investigators
Nov 10, 2020
PURPOSE: The Quality of Life after Brain Injury overall scale (QOLIBRI-OS) measures health-related quality of life (HRQoL) after traumatic brain injury (TBI). The aim of this study was to derive value sets for the QOLIBRI-OS in...
Health utilities Health-related quality of life Quality of life after brain injury overall scale (QOLIBRI-OS) Traumatic brain injury Value set Adolescent Adult Aged Brain Injuries Traumatic Female Humans Italy Male Middle Aged Netherlands Quality of life Surveys and Questionnaires United Kingdom Young Adult
Effects of Brief Dry Cupping on Muscle Soreness in the Gastrocnemius Muscle and Flexibility of the Ankle
OBJECTIVES The purpose of this study was to analyze the effects of brief dry cupping on muscle soreness of the gastrocnemius muscle and range of motion (ROM) in the ankle. METHODS Thirty-six participants (age=29±10 yrs...
Published by: Digital Commons @ Texas A&M University-San Antonio
Variable Resistance Training Combined With Static Traction Computer Vision Applied in Neck and Shoulder Rehabilitation Training for College Students
This study evaluates the effectiveness of static traction combined with variable resistance training in rehabilitating college students with neck and shoulder diseases. Ninety students were randomly assigned to receive either...
Published by: IGI Global Scientific Publishing
Self-Reported Comfort and Competencies for Pain Among Undergraduate Medical Students at Memorial University
Background: Pain is a unique, multifaceted and poorly understood topic. Research has found prevalent gaps in knowledge regarding pain management in medicine, partially stemming from inadequate coverage in undergraduate medical...
Published by: Memorial University Libraries
Composite Measures for Routine Clinical Practice in Psoriatic Arthritis
OBJECTIVE: To test shortened versions of the psoriatic arthritis (PsA) composite measures for use in routine clinical practice.
METHODS: Clinical and patient-reported outcome measures (PROMs) were assessed in patients...
Finding “H” in HRI
The study examines the relationship between the big five personality traits (extroversion, agreeableness, conscientiousness, neuroticism, and openness) and robot likeability and successful HRI implementation in varying...
Published by: IGI Global Scientific Publishing
Composite Measures for Routine Clinical Practice in Psoriatic Arthritis
OBJECTIVE: To test shortened versions of the psoriatic arthritis (PsA) composite measures for use in routine clinical practice.
METHODS: Clinical and patient-reported outcome measures (PROMs) were assessed in patients...
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