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Results: 135
Telerehabilitation after total knee replacement in Italy
OBJECTIVES: To assess cost-effectiveness and cost utility of telerehabilitation (TR) versus standard rehabilitation (SR) after total knee replacement (TKR). DESIGN: Markov decision modelling of cost-effectiveness and...
health economics rehabilitation medicine Arthroplasty Replacement Knee Cost-Benefit Analysis Female Humans Italy Male Markov Chains Models Economic Physical Therapy Modalities Practice Guidelines as Topic Primary Health Care Program Evaluation Quality of life Telerehabilitation Treatment Outcome
Published by: BMJ Open
Texture Analysis of T1 weighted and fluid attenuated inversion recovery images detects abnormalities which correlate with disease progression in small vessel disease
Background and Purpose
MRI techniques may be useful to assess disease severity in cerebral small vessel disease (SVD), identify those individuals who are most likely to progress to dementia, monitor disease progression and act...
Evaluation of a worldwide EQA scheme for complex clonality analysis of clinical lymphoproliferative cases demonstrates a learning effect.
Cleo Keppens, Elke Boone, Paula Gameiro, Véronique Tack, Elisabeth Moreau, Elizabeth Hodges, Paul Evans, Monika Brüggemann, Ian Carter, Dido Lenze, Maria Eugenia Sarasquete, Markus Möbs, Hongxiang Liu, Elisabeth MC Dequeker, Patricia JTA Groenen
Aug 14, 2021
Clonality analysis of immunoglobulin (IG) or T-cell receptor (TR) gene rearrangements is routine practice to assist diagnosis of lymphoid malignancies. Participation in external quality assessment (EQA) aids laboratories in...
Clonality analysis external quality assessment IG rearrangements TCR rearrangements Gene Rearrangement Genes Immunoglobulin Genes T-Cell Receptor Humans Laboratory Proficiency Testing Lymphoproliferative Disorders Molecular Diagnostic Techniques Observer Variation Polymerase Chain Reaction Predictive Value of Tests Quality Assurance Health Care Quality Control Reproducibility of Results
Quantification of protein-protein interactions and activation dynamics
Oncogene dysregulation is a driver of neoplasia development and progression. The use of quantitative molecular imaging to quantify oncogene activation will be crucial in developing companion diagnostics which can identify...
Quantification of protein-protein interactions and activation dynamics
Oncogene dysregulation is a driver of neoplasia development and progression. The use of quantitative molecular imaging to quantify oncogene activation will be crucial in developing companion diagnostics which can identify...
Longitudinal decline in structural networks predicts dementia in cerebral small vessel disease.
Andrew J Lawrence, Eva A Zeestraten, Philip Benjamin, Christian P Lambert, Robin G Morris, Thomas R Barrick, Hugh S Markus
May 23, 2018
OBJECTIVE: To determine whether longitudinal change in white matter structural network integrity predicts dementia and future cognitive decline in cerebral small vessel disease (SVD). To investigate whether network disruption...
What made Stan Wood a great collector?
Stan Wood was an exceptional fossil collector who, over a collecting career of more than 40 years, provided British palaeontology with an abundance and variety of new Carboniferous fossils the like of which had not been...
Pattern and Rate of Cognitive Decline in Cerebral Small Vessel Disease
Andrew J Lawrence, Rebecca L Brookes, Eva A Zeestraten, Thomas R Barrick, Robin G Morris, Hugh S Markus
Jul 28, 2015
Involvement of the reward network is associated with apathy in cerebral small vessel disease.
Danuta M Lisiecka-Ford, Daniel J Tozer, Robin G Morris, Andrew J Lawrence, Thomas R Barrick, Hugh S Markus
May 01, 2018
INTRODUCTION: Apathy is a common yet under-recognised feature of cerebral small vessel disease (SVD), but its underlying neurobiological basis is not yet understood. We hypothesized that damage to the reward network is...
The Effect of Technology Readiness on Individual Absorptive Capacity Toward Learning Behavior in Australian Universities
Recipient's absorptive capacity (ACAP) is a barrier to knowledge transfer in organizations. The technology readiness (TR) dimensions measure an individual's technological beliefs and aligns with the individual's ACAP. The...
Published by: IGI Global Scientific Publishing
The logic of transcriptional regulator recruitment architecture at cis-regulatory modules controlling liver functions.
Julie Dubois-Chevalier, Vanessa Dubois, Hélène Dehondt, Parisa Mazrooei, Claire Mazuy, Aurélien A Sérandour, Céline Gheeraert, Penderia Guillaume, Eric Baugé, Bruno Derudas, Nathalie Hennuyer, Réjane Paumelle, Guillemette Marot, Jason S Carroll, Mathieu Lupien, Bart Staels, Philippe Lefebvre, Jérôme Eeckhoute
Jul 12, 2019
Control of gene transcription relies on concomitant regulation by multiple transcriptional regulators (TRs). However, how recruitment of a myriad of TRs is orchestrated at cis-regulatory modules (CRMs) to account for...
Differential relationships between apathy and depression with white matter microstructural changes and functional outcomes.
Matthew J Hollocks, Andrew J Lawrence, Rebecca L Brookes, Thomas R Barrick, Robin G Morris, Masud Husain, Hugh S Markus
Sep 15, 2015
Information Sharing on Social Media by Multicultural Individuals
Drawing upon social cognitive & social network theories, this study examines individual-level and network-level factors which potentially affect multicultural individuals’ information sharing behavior via social media. The data...
Published by: IGI Global Scientific Publishing
Sex Differences in Autism Spectrum Disorder based on DSM-5 Criteria
In the absence of intellectual impairment autism spectrum disorder (ASD) is diagnosed both less and later in females. This study used clinician and teacher report to explore sex differences in the behavioural presentation of 69...
Sex Differences in Autism Spectrum Disorder based on DSM-5 Criteria
In the absence of intellectual impairment autism spectrum disorder (ASD) is diagnosed both less and later in females. This study used clinician and teacher report to explore sex differences in the behavioural presentation of 69...
Glacier characteristics and retreat between 1991 and 2014 in the Ladakh Range, Jammu and Kashmir
Glaciers in the Ladakh Range lie between the Himalaya, a monsoon-forced region of glacier retreat, and the Karakoram, a region of anomalous glacier stability driven by mid-latitude westerlies. Given this context, glaciers might...
Predicting Dementia in Cerebral Small Vessel Disease Using an Automatic Diffusion Tensor Image Segmentation Technique.
Owen A Williams, Eva A Zeestraten, Philip Benjamin, Christian Lambert, Andrew J Lawrence, Andrew D MacKinnon, Robin G Morris, Hugh S Markus, Thomas R Barrick, Rebecca A Charlton
Oct 03, 2019
Background and Purpose- Cerebral small vessel disease (SVD) is the most common cause of vascular cognitive impairment, with a significant proportion of cases going on to develop dementia. We explore the extent to which diffusion...
Brain cerebral small vessel disease Cerebrum Cognition Cognitive Dysfunction Dementia Diffusion tensor imaging Adult Aged Aged 80 and over cerebral small vessel diseases Cognitive Dysfunction Dementia Diffusion tensor imaging Disease Progression Female Humans Image Interpretation Computer-Assisted Male Middle Aged
Identifying preclinical vascular dementia in symptomatic small vessel disease using MRI.
Christian Lambert, Eva Zeestraten, Owen Williams, Philip Benjamin, Andrew J Lawrence, Robin G Morris, Andrew D MacKinnon, Thomas R Barrick, Hugh S Markus
Oct 18, 2018
Sporadic cerebral small vessel disease is an important cause of vascular dementia, a syndrome of cognitive impairment together with vascular brain damage. At post-mortem pure vascular dementia is rare, with evidence of...
cerebral small vessel disease Preclinical dementia Structural MRI Vascular dementia voxel-based morphometry Aged Aged 80 and over Brain cerebral small vessel diseases Dementia Vascular Early Diagnosis Female Humans Magnetic Resonance Imaging Male Middle Aged Neuroimaging Neuropsychological Tests white matter
Apathy is associated with large-scale white matter network disruption in small vessel disease.
Jonathan Tay, Anil M Tuladhar, Matthew J Hollocks, Rebecca L Brookes, Daniel J Tozer, Thomas R Barrick, Masud Husain, Frank-Erik de Leeuw, Hugh S Markus
Jan 16, 2019
OBJECTIVE: To investigate whether white matter network disruption underlies the pathogenesis of apathy, but not depression, in cerebral small vessel disease (SVD). METHODS: Three hundred thirty-one patients with SVD from the...
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