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Vortex coupling in trailing vortex-wing interactions
The interaction of trailing vortices of an upstream wing with rigid and flexible downstream wings has been investigated experimentally in a wind tunnel, using particle image velocimetry, hot-wire, force and deformation...
Vortex coupling in trailing vortex-wing interactions
The interaction of trailing vortices of an upstream wing with rigid and flexible downstream wings has been investigated experimentally in a wind tunnel, using particle image velocimetry, hot-wire, force and deformation...
Secondary Metabolites of Osmanthus fragrans
Chen-Chen Fu, Fa-Ying Xu, Yu-Chen Qian, Hoi-Lun Koo, Yi-Fan Duan, Geng-Min Weng, Tai-Ping Fan, Mo-Xian Chen, Fu-Yuan Zhu
Aug 01, 2022
Osmanthus fragrans (scientific name: Osmanthus fragrans (Thunb.) Lour.) is a species of the Osmanthus genus in the family Oleaceae, and it has a long history of cultivation in China. O. fragrans is edible and is well known for...
CAMKs support development of acute myeloid leukemia.
Xunlei Kang, Changhao Cui, Chen Wang, Guojin Wu, Heyu Chen, Zhigang Lu, Xiaoli Chen, Li Wang, Jie Huang, Huimin Geng, Meng Zhao, Zhengshan Chen, Markus Müschen, Huan-You Wang, Cheng Cheng Zhang
Oct 03, 2018
BACKGROUND: We recently identified the human leukocyte immunoglobulin-like receptor B2 (LILRB2) and its mouse ortholog-paired Ig-like receptor (PirB) as receptors for several angiopoietin-like proteins (Angptls). We also...
acute myeloid leukemia CAMK CREB LILRB2 Leukemic stem cell PirB Animals Calcium-Calmodulin-Dependent Protein Kinases Carcinogenesis Cell Line Tumor Disease Models Animal Disease Progression Humans Leukemia Myeloid Acute Mice Inbred C57BL Neoplastic Stem Cells Receptors Immunologic Signal Transduction
Measurement of single top-quark production in association with a W boson in the single-lepton channel at √s=8TeV with the ATLAS detector
G Aad, B Abbott, DC Abbott, AA Abud, K Abeling, DK Abhayasinghe, SH Abidi, OS AbouZeid, NL Abraham, H Abramowicz, H Abreu, Y Abulaiti, BS Acharya, B Achkar, S Adachi, L Adam, CA Bourdarios, L Adamczyk, L Adamek, J Adelman, M Adersberger, A Adiguzel, S Adorni, T Adye, AA Affolder, Y Afik, C Agapopoulou, MN Agaras, A Aggarwal, C Agheorghiesei, JA Aguilar-Saavedra, F Ahmadov, WS Ahmed, X Ai, G Aielli, S Akatsuka, TPA Åkesson, E Akilli, AV Akimov, KA Khoury, GL Alberghi, J Albert, MJA Verzini, S Alderweireldt, M Aleksa, IN Aleksandrov, C Alexa, D Alexandre, T Alexopoulos, A Alfonsi, F Alfonsi, M Alhroob, B Ali, M Aliev, G Alimonti, J Alison, SP Alkire, C Allaire, BMM Allbrooke, BW Allen, PP Allport, A Aloisio, A Alonso, F Alonso, C Alpigiani, AA Alshehri, MA Estevez, DÁ Piqueras, MG Alviggi, YA Coutinho, A Ambler, L Ambroz, C Amelung, D Amidei, SPAD Santos, S Amoroso, CS Amrouche, F An, C Anastopoulos, N Andari, T Andeen, CF Anders, JK Anders, A Andreazza, V Andrei, CR Anelli, S Angelidakis, A Angerami, AV Anisenkov, A Annovi, C Antel, MT Anthony, E Antipov, M Antonelli, DJA Antrim, F Anulli, M Aoki, JAA Pozo, LA Bella, G Arabidze
Oct 07, 2021
The production cross-section of a top quark in association with a $W$ boson
is measured using proton-proton collisions at $\sqrt{s} = 8$ TeV. The dataset
corresponds to an integrated luminosity of 20.2 fb$^{-1}$, and was...
Revealing the Drag Instability in One-fluid Nonideal Magnetohydrodynamic Simulations of a 1D Isothermal C-shock
Abstract
C-type shocks are believed to be ubiquitous in turbulent molecular clouds thanks to ambipolar diffusion. We investigate whether the drag instability in 1D isothermal...
The different catalytic roles of the metal- binding ligands in human 4-hydroxyphenylpyruvate dioxygenase
Chih-Wei Huang, Hsiu-Chen Liu, Chia-Pei Shen, Yi-Tong Chen, Sung-Jai Lee, Matthew D. Lloyd, Hwei-Jen Lee
May 01, 2016
4‐Hydroxylphenylpyruvatedioxygenase (HPPD) is a non‐haem iron(II)‐dependent oxygenase that catalyzes the conversion of 4‐hydroxylphenylpyruvate (HPP) to homogentisate (HG). In the active site, a strictly conserved 2‐His‐1‐Glu...
Distribution of horseradish peroxidase (HRP)- anti-HRP immune complexes in mouse spleen with special reference to follicular dendritic cells
The distribution of immune complexes has been studied in mouse spleen stimulated to contain many germinal centers (GC?s). Horseradish peroxidase (HRP)-anti-HRP complexes were used as an appropriately precise and sensitive model....
Published by: Rockefeller University
Cross-species studies of cognition relevant to drug discovery
TW Robbins
Mar 02, 2018
Commentary on brain-derived neurotrophic factor and the orbitofrontal regulation of behavior
TW Robbins
Jan 26, 2017
Whereas contemporary neuroimaging evidence supports a role for dysfunctioning prefrontal-amygdaloid-striatal circuitry in affective disorders, precise psychological functions of this interaction have still to be revealed, thus...
Genomic footprints of activated telomere maintenance mechanisms in cancer.
Lina Sieverling, Chen Hong, Sandra D Koser, Philip Ginsbach, Kortine Kleinheinz, Barbara Hutter, Delia M Braun, Isidro Cortés-Ciriano, Ruibin Xi, Rolf Kabbe, Peter J Park, Roland Eils, Matthias Schlesner, PCAWG-Structural Variation Working Group, Benedikt Brors, Karsten Rippe, David TW Jones, Lars Feuerbach, PCAWG Consortium
Mar 05, 2021
Cancers require telomere maintenance mechanisms for unlimited replicative potential. They achieve this through TERT activation or alternative telomere lengthening associated with ATRX or DAXX loss. Here, as part of the ICGC/TCGA...
The different catalytic roles of the metal- binding ligands in human 4-hydroxyphenylpyruvate dioxygenase
Chih-Wei Huang, Hsiu-Chen Liu, Chia-Pei Shen, Yi-Tong Chen, Sung-Jai Lee, Matthew D. Lloyd, Hwei-Jen Lee
May 01, 2016
4‐Hydroxylphenylpyruvatedioxygenase (HPPD) is a non‐haem iron(II)‐dependent oxygenase that catalyzes the conversion of 4‐hydroxylphenylpyruvate (HPP) to homogentisate (HG). In the active site, a strictly conserved 2‐His‐1‐Glu...
DNMTs Play an Important Role in Maintaining the Pluripotency of Leukemia Inhibitory Factor-Dependent Embryonic Stem Cells.
Baojiang Wu, Yunxia Li, Bojiang Li, Baojing Zhang, Yanqiu Wang, Lin Li, Junpeng Gao, Yuting Fu, Shudong Li, Chen Chen, M Azim Surani, Fuchou Tang, Xihe Li, Siqin Bao
Apr 16, 2021
Naive pluripotency can be maintained in medium with two inhibitors plus leukemia inhibitory factor (2i/LIF) supplementation, which primarily affects canonical WNT, FGF/ERK, and JAK/STAT3 signaling. However, whether one of these...
DNA Methylation DNMTs DIFFERENTIATION Embryonic Stem Cells epigenetic Genomic Imprinting Leukemia Inhibitory Factor MOUSE Pluripotency self-renew Animals Cell Culture Techniques Cell Differentiation Cell Self Renewal Cells Cultured Culture Media DNA (Cytosine-5-)-Methyltransferases DNA Methylation DNA Methyltransferase 3A Gene Expression Regulation Developmental Gene Knockout Techniques Genomic Imprinting Germ Layers Janus Kinases Leukemia Inhibitory Factor Mice Mice Inbred C57BL Mice Transgenic Mouse embryonic stem cells STAT3 Transcription Factor Signal Transduction Transcriptome
Impact of Irradiation on the Pharmacokinetics and Biotransformation of Tamoxifen.
Yung-Yi Cheng, Teresa Zheng, Michael W Chang, Jeffrey W Dalley, Yu-Jen Chen, Tung-Hu Tsai, Chen-Hsi Hsieh
Mar 03, 2022
BACKGROUND: The optimal procedure for combining radiotherapy (RT) with tamoxifen treatment is controversial as RT may alter the pharmacokinetics and biotransformation of tamoxifen. The present study investigated this potential...
Investigation of anterior cingulate cortex gamma-aminobutyric acid and glutamate-glutamine levels in obsessive-compulsive disorder using magnetic resonance spectroscopy.
Yan Li, Chen Cheng Zhang, Kathrin Weidacker, Yingying Zhang, Naying He, Haiyan Jin, Weibo Chen, Valerie Voon, Richard AE Edden, Fuhua Yan
Aug 21, 2019
BACKGROUND: Obsessive-compulsive disorder (OCD) is a relatively common and disabling psychiatric disorder whose pathophysiology is incompletely understood. In this study, we utilized magnetic resonance spectroscopy (MRS) in an...
Habits.
What is a habit? One problem with the concept of habit has been that virtually everyone has their own ideas of what is meant by such a term. Whilst not eschewing folk psychology, it is useful to re-examine dictionary definitions...
A suboptimal maternal diet combined with accelerated postnatal growth results in an altered aging profile in the thymus of male rats.
Jane L Tarry-Adkins, Catherine E Aiken, Thomas J Ashmore, Denise S Fernandez-Twinn, Jian-Hua Chen, Susan E Ozanne
Sep 05, 2018
Reduced fetal nutrition and rapid postnatal growth accelerates the aging phenotype in many organ systems; however, effects on the immune system are unclear. We addressed this by studying the thymus from a rat model of...
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