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Explaining Low Rates of Autism Among Hispanic Schoolchildren in Texas
In data from the Texas Educational Agency and the Health Resources and Services Administration, we found fewer autism diagnoses in school districts with higher percentages of Hispanic children. Our results are consistent with...
Published by: Digital Commons @ Texas A&M University-San Antonio
Explaining Low Rates of Autism Among Hispanic Schoolchildren in Texas
In data from the Texas Educational Agency and the Health Resources and Services Administration, we found fewer autism diagnoses in school districts with higher percentages of Hispanic children. Our results are consistent with...
Published by: Digital Commons @ Texas A&M University-San Antonio
Explaining Low Rates of Autism Among Hispanic Schoolchildren in Texas
In data from the Texas Educational Agency and the Health Resources and Services Administration, we found fewer autism diagnoses in school districts with higher percentages of Hispanic children. Our results are consistent with...
Published by: Digital Commons @ Texas A&M University-San Antonio
A fate-map for cranial sensory ganglia in the sea lamprey.
Melinda S Modrell, Dorit Hockman, Benjamin Uy, David Buckley, Tatjana Sauka-Spengler, Marianne E Bronner, Clare VH Baker
Dec 18, 2015
Insights into olfactory ensheathing cell development from a laser-microdissection and transcriptome-profiling approach.
Surangi N Perera, Ruth M Williams, Rachel Lyne, Oliver Stubbs, Dennis P Buehler, Tatjana Sauka-Spengler, Masaharu Noda, Gos Micklem, E Michelle Southard-Smith, Clare VH Baker
Jun 01, 2020
lncRNA Spehd Regulates Hematopoietic Stem and Progenitor Cells and Is Required for Multilineage Differentiation.
M Joaquina Delás, Benjamin T Jackson, Tatjana Kovacevic, Silvia Vangelisti, Ester Munera Maravilla, Sophia A Wild, Eva Maria Stork, Nicolas Erard, Simon RV Knott, Gregory J Hannon
Apr 05, 2019
HSC Hematopoiesis lncRNA Oxidative Phosphorylation Animals Bone Marrow Transplantation Cell Differentiation Cell Line Tumor Cell Lineage Cyclin-Dependent Kinase 6 Female GATA2 Transcription Factor Hematopoiesis Hematopoietic Stem Cells Mice Mice Inbred C57BL Oxidative Phosphorylation Proto-Oncogene Proteins RNA Interference RNA Long Noncoding RNA Small Interfering Regeneration Trans-Activators
A combination of urinary biomarker panel and PancRISK score for earlier detection of pancreatic cancer
Analysis of therapy monitoring in the International Congenital Adrenal Hyperplasia Registry.
Neil Lawrence, Irina Bacila, Jeremy Dawson, Jillian Bryce, Salma R Ali, Erica LT van den Akker, Tânia ASS Bachega, Federico Baronio, Niels H Birkebaek, Walter Bonfig, Hedi C van der Grinten, Eduardo C Costa, Liat de Vries, Heba Elsedfy, Ayla Güven, Sabine Hannema, Violeta Iotova, Hetty J van der Kamp, María Clemente, Corina R Lichiardopol, Tatjana Milenkovic, Uta Neumann, Ana Nordenström, Şukran Poyrazoğlu, Ursina Probst-Scheidegger, Luisa De Sanctis, Rieko Tadokoro-Cuccaro, Ajay Thankamony, Ana Vieites, Zehra Yavaş, Syed Faisal Ahmed, Nils Krone
Jul 12, 2022
SIL1 deficiency causes degenerative changes of peripheral nerves and neuromuscular junctions in fish, mice and human.
Vietxuan Phan, Dan Cox, Silvia Cipriani, Sally Spendiff, Stephan Buchkremer, Emily O'Connor, Rita Horvath, Hans Hilmar Goebel, Denisa Hathazi, Hanns Lochmüller, Tatjana Straka, Rüdiger Rudolf, Joachim Weis, Andreas Roos
Dec 20, 2018
BACKGROUND: Marinesco-Sjögren Syndrome (MSS) is a rare neuromuscular condition caused by recessive mutations in the SIL1 gene resulting in the absence of functional SIL1 protein, a co-chaperone for the major ER chaperone, BiP....
Retinoic acid signaling modulation guides in vitro specification of human heart field-specific progenitor pools.
Dorota Zawada, Jessica Kornherr, Anna B Meier, Gianluca Santamaria, Tatjana Dorn, Monika Nowak-Imialek, Daniel Ortmann, Fangfang Zhang, Mark Lachmann, Martina Dreßen, Mariaestela Ortiz, Victoria L Mascetti, Stephen C Harmer, Muriel Nobles, Andrew Tinker, Maria Teresa De Angelis, Roger A Pedersen, Phillip Grote, Karl-Ludwig Laugwitz, Alessandra Moretti, Alexander Goedel
Apr 17, 2023
Cardiogenesis relies on the precise spatiotemporal coordination of multiple progenitor populations. Understanding the specification and differentiation of these distinct progenitor pools during human embryonic development is...
Myocardium Heart Myocytes Cardiac Pluripotent Stem Cells Animals Humans Mice Tretinoin Cell Differentiation
Published by: Nature Communications
Retinoic acid signaling modulation guides in vitro specification of human heart field-specific progenitor pools.
Dorota Zawada, Jessica Kornherr, Anna B Meier, Gianluca Santamaria, Tatjana Dorn, Monika Nowak-Imialek, Daniel Ortmann, Fangfang Zhang, Mark Lachmann, Martina Dreßen, Mariaestela Ortiz, Victoria L Mascetti, Stephen C Harmer, Muriel Nobles, Andrew Tinker, Maria Teresa De Angelis, Roger A Pedersen, Phillip Grote, Karl-Ludwig Laugwitz, Alessandra Moretti, Alexander Goedel
Apr 04, 2023
Impact of dexamethasone on SARS-CoV-2 concentration kinetics and antibody response in hospitalized COVID-19 patients
Barbara Mühlemann, Charlotte Thibeault, David Hillus, Elisa T Helbig, Lena J Lippert, Pinkus Tober-Lau, Tatjana Schwarz, Marcel A Müller, Pa-COVID-19 collaborative study group, Martin Witzenrath, Norbert Suttorp, Leif E Sander, Christian Drosten, Terry C Jones, Victor M Corman, Florian Kurth
Jul 28, 2021
OBJECTIVES: Dexamethasone has become the standard of care for severe coronavirus disease 2019 (COVID-19), but its virological impact is poorly understood. The objectives of this work were to characterize the kinetics of severe...
Antibody COVID-19 Nucleic Acid Testing Coronavirus disease 2019 (COVID-19) Dexamethasone Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Viral concentration Anti-Inflammatory Agents Antibodies Viral covid-19 Dexamethasone Hospitalization Humans Immunoglobulin A Immunoglobulin G Kinetics Prospective Studies RNA Viral Respiratory System SARS-CoV-2 Seroconversion Viral Load COVID-19 Drug Treatment
Carotid intima-media thickness progression to predict cardiovascular events in the general population (the PROG-IMT collaborative project)
Matthias W Lorenz, Joseph F Polak, Maryam Kavousi, Ellisiv B Mathiesen, Henry Völzke, Tomi-Pekka Tuomainen, Dirk Sander, Matthieu Plichart, Alberico L Catapano, Christine M Robertson, Stefan Kiechl, Tatjana Rundek, Moïse Desvarieux, Lars Lind, Caroline Schmid, Pronabesh DasMahapatra, Lu Gao, Kathrin Ziegelbauer, Michiel L Bots, Simon G Thompson, PROG-IMT Study Group
Jun 10, 2019
A combination of urinary biomarker panel and PancRISK score for earlier detection of pancreatic cancer
Silvana Debernardi, Harrison O'Brien, Asma S Algahmdi, Nuria Malats, Grant D Stewart, Marija Plješa-Ercegovac, Eithne Costello, William Greenhalf, Amina Saad, Rhiannon Roberts, Alexander Ney, Stephen P Pereira, Hemant M Kocher, Stephen Duffy, Oleg Blyuss, Tatjana Crnogorac-Jurcevic
Nov 23, 2020
BACKGROUND: Pancreatic ductal adenocarcinoma (PDAC) is one of the deadliest cancers, with around 9% of patients surviving >5 years. Asymptomatic in its initial stages, PDAC is mostly diagnosed late, when already a locally...
Adult Aged Aged 80 and over Antigens Tumor-Associated Carbohydrate Biomarkers Tumor Carcinoma Pancreatic Ductal Early Detection of Cancer Europe Female Humans Lithostathine Male Middle Aged Pancreatic Neoplasms Predictive Value of Tests Reproducibility of Results Retrospective Studies Trefoil Factor-1 Urinalysis Vesicular Transport Proteins Young Adult
ATM orchestrates the DNA-damage response to counter toxic non-homologous end-joining at broken replication forks.
Gabriel Balmus, Domenic Pilger, Julia Coates, Mukerrem Demir, Matylda Sczaniecka-Clift, Ana C Barros, Michael Woods, Beiyuan Fu, Fengtang Yang, Elisabeth Chen, Matthias Ostermaier, Tatjana Stankovic, Hannes Ponstingl, Mareike Herzog, Kosuke Yusa, Francisco Munoz Martinez, Stephen T Durant, Yaron Galanty, Petra Beli, David J Adams, Allan Bradley, Emmanouil Metzakopian, Josep V Forment, Stephen P Jackson
Jan 17, 2019
Mutations in the ATM tumor suppressor gene confer hypersensitivity to DNA-damaging chemotherapeutic agents. To explore genetic resistance mechanisms, we performed genome-wide CRISPR-Cas9 screens in cells treated with the DNA...
Animals Antineoplastic Agents Ataxia Telangiectasia Mutated Proteins BRCA1 Protein CRISPR-Cas Systems Cell Line Tumor Cell Survival DNA Breaks Double-Stranded DNA End-Joining Repair DNA Ligase ATP DNA Replication Drug Resistance Neoplasm Female Humans Mice Mice Inbred NOD Mice Knockout Mouse embryonic stem cells Mutation Neoplasms Experimental Phthalazines Piperazines Topotecan
scRNA-Seq reveals distinct stem cell populations that drive hair cell regeneration after loss of Fgf and Notch signaling.
Mark E Lush, Daniel C Diaz, Nina Koenecke, Sungmin Baek, Helena Boldt, Madeleine K St Peter, Tatiana Gaitan-Escudero, Andres Romero-Carvajal, Elisabeth M Busch-Nentwich, Anoja G Perera, Kathryn E Hall, Allison Peak, Jeffrey S Haug, Tatjana Piotrowski
Apr 29, 2019
Loss of sensory hair cells leads to deafness and balance deficiencies. In contrast to mammalian hair cells, zebrafish ear and lateral line hair cells regenerate from poorly characterized support cells. Equally ill-defined is the...
Interplay of cell-cell contacts and RhoA/MRTF-A signaling regulates cardiomyocyte identity.
Tatjana Dorn, Jessica Kornherr, Elvira I Parrotta, Dorota Zawada, Harold Ayetey, Gianluca Santamaria, Laura Iop, Elisa Mastantuono, Daniel Sinnecker, Alexander Goedel, Ralf J Dirschinger, Ilaria My, Svenja Laue, Tarik Bozoglu, Christian Baarlink, Tilman Ziegler, Elisabeth Graf, Rabea Hinkel, Giovanni Cuda, Stefan Kääb, Andrew A Grace, Robert Grosse, Christian Kupatt, Thomas Meitinger, Austin G Smith, Karl-Ludwig Laugwitz, Alessandra Moretti
Sep 13, 2018
Cell-cell and cell-matrix interactions guide organ development and homeostasis by controlling lineage specification and maintenance, but the underlying molecular principles are largely unknown. Here, we show that in human...
Socioeconomic disparities in physical activity, sedentary behavior and sleep patterns among 6- to 9-year-old children from 24 countries in the WHO European region
Sanja Musić Milanović, Marta Buoncristiano, Helena Križan, Giulia Rathmes, Julianne Williams, Jolanda Hyska, Vesselka Duleva, Hana Zamrazilová, Tatjana Hejgaard, Maja Bæksgaard Jørgensen, Benoît Salanave, Lela Shengelia, Cecily C. Kelleher, Angela Spinelli, Paola Nardone, Shynar Abdrakhmanova, Zhamilya Usupova, Iveta Pudule, Ausra Petrauskiene, Victoria Farrugia Sant'Angelo, Enisa Kujundžić, Anna Fijałkowska, Ana Isabel Rito, Alexandra Cucu, Lacramioara Aurelia Brinduse, Valentina Peterkova, Andrea Gualtieri, Marta García-Solano, Enrique Gutiérrez-González, Khadichamo Boymatova, Mahmut S. Yardim, Maya Tanrygulyyeva, Marina Melkumova, Daniel Weghuber, Eha Nurk, Päivi Mäki, Ingunn Holden Bergh, Sergej M. Ostojic, Kenisha Russell Jonsson, Igor Spiroski, Harry Rutter, Wolfgang Ahrens, Ivo Rakovac, Stephen Whiting, João Breda
Nov 30, 2021
Physical activity, sedentary behavior, and sleep are important predictors of children's health. This paper aimed to investigate socioeconomic disparities in physical activity, sedentary behavior, and sleep across the WHO...
physical activity Sedentary Behavior Sleep Hygiene social inequalities /dk/atira/pure/subjectarea/asjc/2700/2712 name=Endocrinology, Diabetes and Metabolism /dk/atira/pure/subjectarea/asjc/2700/2739 name=Public Health, Environmental and Occupational Health /dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_being name=SDG 3 - Good Health and Well-being
Subtype Specificity of Genetic Loci Associated With Stroke in 16 664 Cases and 32 792 Controls.
Matthew Traylor, Christopher D Anderson, Loes CA Rutten-Jacobs, Guido J Falcone, Mary E Comeau, Hakan Ay, Cathie LM Sudlow, Huichun Xu, Braxton D Mitchell, John W Cole, Kathryn Rexrode, Jordi Jimenez-Conde, Reinhold Schmidt, Raji P Grewal, Ralph Sacco, Marta Ribases, Tatjana Rundek, Jonathan Rosand, Martin Dichgans, Jin-Moo Lee, Carl D Langefeld, Steven J Kittner, Hugh S Markus, Daniel Woo, Rainer Malik, NINDS Stroke Genetics Network (SiGN) and International Stroke Genetics Consortium (ISGC)
Jul 01, 2019
Genetic basis of lacunar stroke
Matthew Traylor, Elodie Persyn, Liisa Tomppo, Sofia Klasson, Vida Abedi, Mark K Bakker, Nuria Torres, Linxin Li, Steven Bell, Loes Rutten-Jacobs, Daniel J Tozer, Christoph J Griessenauer, Yanfei Zhang, Annie Pedersen, Pankaj Sharma, Jordi Jimenez-Conde, Tatjana Rundek, Raji P Grewal, Arne Lindgren, James F Meschia, Veikko Salomaa, Aki Havulinna, Christina Kourkoulis, Katherine Crawford, Sandro Marini, Braxton D Mitchell, Steven J Kittner, Jonathan Rosand, Martin Dichgans, Christina Jern, Daniel Strbian, Israel Fernandez-Cadenas, Ramin Zand, Ynte Ruigrok, Natalia Rost, Robin Lemmens, Peter M Rothwell, Christopher D Anderson, Joanna Wardlaw, Cathryn M Lewis, Hugh S Markus, Study Dutch Parelsnoer Institute-Cerebrovascular Accident (CVA) Study Group Helsinki Stroke, National Institute of Neurological Disorders and Stroke (NINDS) Stroke Genetics Network, UK DNA Lacunar Stroke Study Investigators, International Stroke Genetics Consortium
Apr 01, 2021
BACKGROUND: The genetic basis of lacunar stroke is poorly understood, with a single locus on 16q24 identified to date. We sought to identify novel associations and provide mechanistic insights into the disease. METHODS: We did a...
Urban and rural differences in frequency of fruit, vegetable, and soft drink consumption among 6–9-year-old children from 19 countries from the WHO European region
Mirjam M. Heinen, Silvia Bel-Serrat, Cecily C. Kelleher, Marta Buoncristiano, Angela Spinelli, Paola Nardone, Sanja Musić Milanović, Ana Isabel Rito, A. Tülay Bağci Bosi, Enrique Gutiérrrez-González, Iveta Pudule, Shynar Abdrakhmanova, Zulfiya Abdurrahmonova, Lacramioara Aurelia Brinduse, Alexandra Cucu, Vesselka Duleva, Anna Fijałkowska, Andrea Gualtieri, Tatjana Hejgaard, Jolanda Hyska, Enisa Kujundžić, Ausra Petrauskiene, Elena Sacchini, Lela Shengelia, Maya Tanrygulyyeva, Zhamilya Usupova, Ingunn Holden Bergh, Daniel Weghuber, Radka Taxová Braunerová, Marie Kunešová, Victoria Farrugia Sant'Angelo, Eha Nurk, Sergej M. Ostojic, Igor Spiroski, Ľubica Tichá, Harry Rutter, Julianne Williams, Khadichamo Boymatova, Ivo Rakovac, Martin W. Weber, João Breda
Nov 30, 2021
In order to address the paucity of evidence on the association between childhood eating habits and urbanization, this cross-sectional study describes urban–rural differences in frequency of fruit, vegetable, and soft drink...
children Fruit rural soft drinks urban Vegetables /dk/atira/pure/subjectarea/asjc/2700/2712 name=Endocrinology, Diabetes and Metabolism /dk/atira/pure/subjectarea/asjc/2700/2739 name=Public Health, Environmental and Occupational Health /dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_being name=SDG 3 - Good Health and Well-being /dk/atira/pure/sustainabledevelopmentgoals/sustainable_cities_and_communities name=SDG 11 - Sustainable Cities and Communities
Socioeconomic disparities in physical activity, sedentary behavior and sleep patterns among 6- to 9-year-old children from 24 countries in the WHO European region
Sanja Musić Milanović, Marta Buoncristiano, Helena Križan, Giulia Rathmes, Julianne Williams, Jolanda Hyska, Vesselka Duleva, Hana Zamrazilová, Tatjana Hejgaard, Maja Bæksgaard Jørgensen, Benoît Salanave, Lela Shengelia, Cecily C. Kelleher, Angela Spinelli, Paola Nardone, Shynar Abdrakhmanova, Zhamilya Usupova, Iveta Pudule, Ausra Petrauskiene, Victoria Farrugia Sant'Angelo, Enisa Kujundžić, Anna Fijałkowska, Ana Isabel Rito, Alexandra Cucu, Lacramioara Aurelia Brinduse, Valentina Peterkova, Andrea Gualtieri, Marta García-Solano, Enrique Gutiérrez-González, Khadichamo Boymatova, Mahmut S. Yardim, Maya Tanrygulyyeva, Marina Melkumova, Daniel Weghuber, Eha Nurk, Päivi Mäki, Ingunn Holden Bergh, Sergej M. Ostojic, Kenisha Russell Jonsson, Igor Spiroski, Harry Rutter, Wolfgang Ahrens, Ivo Rakovac, Stephen Whiting, João Breda
Nov 30, 2021
Physical activity, sedentary behavior, and sleep are important predictors of children's health. This paper aimed to investigate socioeconomic disparities in physical activity, sedentary behavior, and sleep across the WHO...
physical activity Sedentary Behavior Sleep Hygiene social inequalities /dk/atira/pure/subjectarea/asjc/2700/2712 name=Endocrinology, Diabetes and Metabolism /dk/atira/pure/subjectarea/asjc/2700/2739 name=Public Health, Environmental and Occupational Health /dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_being name=SDG 3 - Good Health and Well-being
Physical activity, screen time, and sleep duration of children aged 6-9 years in 25 countries
Stephen Whiting, Marta Buoncristiano, Peter Gelius, Karim Abu-Omar, Mary Pattison, Jolanda Hyska, Vesselka Duleva, Sanja Musić Milanović, Hana Zamrazilová, Tatjana Hejgaard, Mette Rasmussen, Eha Nurk, Lela Shengelia, Cecily C. Kelleher, Mirjam M. Heinen, Angela Spinelli, Paola Nardone, Akbota Abildina, Shynar Abdrakhmanova, Gulmira Aitmurzaeva, Zhamyila Usuopva, Iveta Pudule, Aušra Petrauskiene, Victoria Farrugia Sant'Angelo, Enisa Kujundzic, Stevo Popovic, Anne Siri Fismen, Ingunn Holden Bergh, Anna Fijalkowska, Ana Isabel Rito, Alexandra Cucu, Lacramioara Aurelia Brinduse, Valentina Peterkova, Andrea Gualtieri, Marta García-Solano, Enrique Gutiérrez-González, Zulfinissio Abdurrahmonova, Khadichamo Boymatova, Nazan Yardim, Maya Tanrygulyyeva, Daniel Weghuber, Karin Schindler, Dragana Stojisavljević, Aida Filipović Hadžiomeragić, Eliza Markidou Ionnaidu, Wolfgang Ahrens, Maria Hassapidou, Viktoria Anna Kovacs, Sergej M. Ostojic, Lubica Ticha, Gregor Starc, Kenisha Russell Jonsson, Igor Spiroski, Harry Rutter, Romeu Mendes, Julianne Williams, Ivo Rakovac, João Breda
Mar 01, 2021
Background: Children are becoming less physically active as opportunities for safe active play, recreational activities, and active transport decrease. At the same time, sedentary screen-based activities both during school...
Active play Active Transport Physical inactivity Sedentary behaviour SURVEILLANCE /dk/atira/pure/subjectarea/asjc/3300/3306 name=Health(social science) /dk/atira/pure/subjectarea/asjc/2700/2737 name=Physiology (medical) /dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_being name=SDG 3 - Good Health and Well-being
Can computer-aided diagnosis assist in the identification of prostate cancer on prostate MRI? a multi-center, multi-reader investigation.
Sonia Gaur, Nathan Lay, Stephanie A Harmon, Sreya Doddakashi, Sherif Mehralivand, Burak Argun, Tristan Barrett, Sandra Bednarova, Rossanno Girometti, Ercan Karaarslan, Ali Riza Kural, Aytekin Oto, Andrei S Purysko, Tatjana Antic, Cristina Magi-Galluzzi, Yesim Saglican, Stefano Sioletic, Anne Y Warren, Leonardo Bittencourt, Jurgen J Fütterer, Rajan T Gupta, Ismail Kabakus, Yan Mee Law, Daniel J Margolis, Haytham Shebel, Antonio C Westphalen, Bradford J Wood, Peter A Pinto, Joanna H Shih, Peter L Choyke, Ronald M Summers, Baris Turkbey
Sep 27, 2018
For prostate cancer detection on prostate multiparametric MRI (mpMRI), the Prostate Imaging-Reporting and Data System version 2 (PI-RADSv2) and computer-aided diagnosis (CAD) systems aim to widely improve standardization across...
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