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Results: 67
Live-cell imaging reveals the spatiotemporal organization of endogenous RNA polymerase II phosphorylation at a single gene.
Linda S Forero-Quintero, William Raymond, Tetsuya Handa, Matthew N Saxton, Tatsuya Morisaki, Hiroshi Kimura, Edouard Bertrand, Brian Munsky, Timothy J Stasevich
Jun 27, 2021
The carboxyl-terminal domain of RNA polymerase II (RNAP2) is phosphorylated during transcription in eukaryotic cells. While residue-specific phosphorylation has been mapped with exquisite spatial resolution along the 1D genome...
Live-cell imaging reveals the spatiotemporal organization of endogenous RNA polymerase II phosphorylation at a single gene
Linda S. Forero-Quintero, William Raymond, Tetsuya Handa, Matthew N. Saxton, Tatsuya Morisaki, Hiroshi Kimura, Edouard Bertrand, Brian Munsky, Timothy J. Stasevich
May 26, 2021
Abstract: The carboxyl-terminal domain of RNA polymerase II (RNAP2) is phosphorylated during transcription in eukaryotic cells. While residue-specific phosphorylation has been mapped with exquisite spatial resolution along the...
Replaying Life's Tape With Intraclonal Germinal Center Evolution
Tatsuya Araki
Jan 01, 0001
Because high-affinity antibodies produced by germinal centers (GCs) are critical in protecting against the ever-increasing array of pathogens, understanding how GC response allows our immune system to recognize a variety of...
Published by: Rockefeller University
Cultural trauma, counter-narratives, and dialogical intellectuals
In this article, we offer a new conceptualization of intellectuals as carriers of cultural trauma through a case study of the Aum Affair, a series of crimes and terrorist attacks committed by the Japanese new religious movement...
Spatial and taxonomic biases in bat records
Biases in data availability have serious consequences on scientific inferences that can be derived. The potential consequences of these biases could be more detrimental in the less-studied megadiverse regions, often...
Rationally Designed Bicyclic Peptides Prevent the Conversion of Aβ42 Assemblies Into Fibrillar Structures
There is great interest in drug discovery programs targeted at the aggregation of the 42-residue form of the amyloid β peptide (Aβ42), since this molecular process is closely associated with Alzheimer’s disease. The use of...
Does governance play a role in the distribution of invasive alien species?
Invasive alien species (IAS) constitute a major threat to global biological diversity. In order to control their spread, a detailed understanding of the factors influencing their distribution is essential. Although international...
Numerical simulation of a hybrid trapped field magnet lens (HTFML) magnetized by pulsed fields
Motoki Shinden, Sora Namba, Tatsuya Hirano, Hiroyuki Fujishiro, Tomoyuki Naito, Mark D Ainslie
Jul 31, 2020
Abstract: The hybrid trapped field magnet lens (HTFML) is a promising device that is able to concentrate a magnetic field higher than an applied background field continuously, even after removing a background field, which was...
Numerical simulation of flux jump behavior in REBaCuO ring bulks with an inhomogeneous J c profile during pulsed-field magnetization
Estimating the risk of species interaction loss in mutualistic communities
Benno I. Simmons, Hannah S. Wauchope, Tatsuya Amano, Lynn V. Dicks, William J. Sutherland, Vasilis Dakos
Sep 11, 2020
Effectively integrating experiments into conservation practice
Nancy Ockendon, Tatsuya Amano, Marc Cadotte, Harriet Downey, Mark H. Hancock, Ann Thornton, Paul Tinsley‐Marshall, William J. Sutherland
May 24, 2021
Review Reviews Controls Experiment evidence Experimental design management trial Manipulation nature conservation replication
Published by: Ecological Solutions and Evidence
Numerical simulation of a hybrid trapped field magnet lens (HTFML) magnetized by pulsed fields
Motoki Shinden, Sora Namba, Tatsuya Hirano, Hiroyuki Fujishiro, Tomoyuki Naito, Mark D Ainslie
Jul 31, 2020
Abstract: The hybrid trapped field magnet lens (HTFML) is a promising device that is able to concentrate a magnetic field higher than an applied background field continuously, even after removing a background field, which was...
ACTIN-RELATED PROTEIN6 Regulates Female Meiosis by Modulating Meiotic Gene Expression in Arabidopsis.
Yuan Qin, Lihua Zhao, Megan I Skaggs, Sebastien Andreuzza, Tatsuya Tsukamoto, Aneesh Panoli, Kirsten N Wallace, Steven Smith, Imran Siddiqi, Zhenbiao Yang, Ramin Yadegari, Ravishankar Palanivelu
Jun 24, 2019
In flowering plants, meiocytes develop from subepidermal cells in anthers and ovules. The mechanisms that integrate gene-regulatory processes with meiotic programs during reproductive development remain poorly characterized....
Genetic association analysis of 77,539 genomes reveals rare disease etiologies.
Daniel Greene, Daniela Pirri, Karen Frudd, Ege Sackey, Mohammed Al-Owain, Arnaud P J Giese, Khushnooda Ramzan, Sehar Riaz, Itaru Yamanaka, Nele Boeckx, Chantal Thys, Bruce D Gelb, Paul Brennan, Verity Hartill, Julie Harvengt, Tomoki Kosho, Sahar Mansour, Mitsuo Masuno, Takako Ohata, Helen Stewart, Khalid Taibah, Claire L S Turner, Faiqa Imtiaz, Saima Riazuddin, Takayuki Morisaki, Pia Ostergaard, Bart L Loeys, Hiroko Morisaki, Zubair M Ahmed, Graeme M Birdsey, Kathleen Freson, Andrew Mumford, Ernest Turro
Apr 17, 2023
The genetic etiologies of more than half of rare diseases remain unknown. Standardized genome sequencing and phenotyping of large patient cohorts provide an opportunity for discovering the unknown etiologies, but this depends on...
Humans Rare Diseases Membrane Proteins Bayes Theorem Genotype Phenotype Genome-Wide Association Study
Published by: Nature medicine
Responses of global waterbird populations to climate change vary with latitude
Tatsuya Amano, Tamás Székely, Hannah S. Wauchope, Brody Sandel, Szabolcs Nagy, Taej Mundkur, Tom Langendoen, Daniel Blanco, Nicole L. Michel, William J. Sutherland
Oct 31, 2020
Most research on climate change impacts on global biodiversity lacks the resolution to detect changes in species abundance and is limited to temperate ecosystems. This limits our understanding of global responses in species...
Responses of global waterbird populations to climate change vary with latitude
Tatsuya Amano, Tamás Székely, Hannah S. Wauchope, Brody Sandel, Szabolcs Nagy, Taej Mundkur, Tom Langendoen, Daniel Blanco, Nicole L. Michel, William J. Sutherland
Oct 31, 2020
Most research on climate change impacts on global biodiversity lacks the resolution to detect changes in species abundance and is limited to temperate ecosystems. This limits our understanding of global responses in species...
The challenge of biased evidence in conservation.
Alec P Christie, Tatsuya Amano, Philip A Martin, Silviu O Petrovan, Gorm E Shackelford, Benno I Simmons, Rebecca K Smith, David R Williams, Claire FR Wordley, William J Sutherland
May 05, 2020
Efforts to tackle the current biodiversity crisis need to be as efficient and effective as possible given chronic underfunding. To inform decision-makers of the most effective conservation actions, it is important to identify...
Bias conservación basada en evidencias conservation evidence conservation research decision-making diseño de estudio evidence-based conservation evidencia de la conservación investigación sobre la conservación Prioritization priorización sesgo study design Synthesis síntesis toma de decisiones 优先保护 保护研究 保护证据 偏倚 决策 基于证据的保护 研究设计 综合分析 Animals Australasia Biodiversity Conservation of Natural Resources Endangered Species Europe North America
Impact of human-derived hemoglobin based oxygen vesicles as a machine perfusion solution for liver donation after cardiac death in a pig model.
Tatsuya Shonaka, Naoto Matsuno, Hiromichi Obara, Ryo Yoshikawa, Yuji Nishikawa, Yo Ishihara, Hiroki Bochimoto, Mikako Gochi, Masahide Otani, Hiroyuki Kanazawa, Hiroshi Azuma, Hiromi Sakai, Hiroyuki Furukawa
Dec 11, 2019
The recent clinical application of perfusion technology for the machine preservation of donation after cardiac death (DCD) grafts has some advantages. Oxygenation has been proposed for the preservation of DCD liver grafts. The...
Adenosine allopurinol Animals Aspartate Aminotransferases Female Glutathione Hemoglobins Hepatic Artery Humans Hydrogen-Ion Concentration Insulin Lactic Acid Liver Liver Transplantation Mitochondria Models Animal Organ Preservation Organ Preservation Solutions Oxygen Oxygen Consumption Raffinose Swine Temperature
Successful conservation of global waterbird populations depends on effective governance
Tatsuya Amano, Tamás Székely, Brody Sandel, Szabolcs Nagy, Taej Mundkur, Tom Langendoen, Daniel Blanco, Candan U. Soykan, William J. Sutherland
Jan 11, 2018
Understanding global patterns of biodiversity change is crucial for conservation research, policies and practices. However, for most ecosystems, the lack of systematically collected data at a global level limits our...
A Gene Regulatory Network for Cellular Reprogramming in Plant Regeneration.
Momoko Ikeuchi, Michitaro Shibata, Bart Rymen, Akira Iwase, Anne-Maarit Bågman, Lewis Watt, Duncan Coleman, David S Favero, Tatsuya Takahashi, Sebastian E Ahnert, Siobhan M Brady, Keiko Sugimoto
May 31, 2018
Wounding triggers organ regeneration in many plant species, and application of plant hormones, such as auxin and cytokinin, enhances their regenerative capacities in tissue culture. Recent studies have identified several key...
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