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An Image Quality Adjustment Framework for Object Detection on Embedded Cameras
Automatic analysis tools are ubiquitously applied on wireless embedded cameras to extract high-level information from raw data. The quality of images may be degraded by factors such as noise and blur introduced during the...
Technology Adoption Model-Based Comparison of Clinical Trial Software
Clinical research management systems are mainly used by both pharmaceutical companies and biotechnology companies to manage the clinical trial process from start to finish. Due to the very nature and complexity of the clinical...
Salicylic Acid and Risk of Colorectal Cancer
Salicylic acid (SA) has observationally been shown to decrease colorectal cancer (CRC) risk. Aspirin (acetylsalicylic acid, that rapidly deacetylates to SA) is an effective primary and secondary chemopreventive agent. Through a...
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Evaluation of vitamin D biosynthesis and pathway target genes reveals UGT2A1/2 and EGFR polymorphisms associated with epithelial ovarian cancer in African American Women.
Delores J Grant, Ani Manichaikul, Anthony J Alberg, Elisa V Bandera, Jill Barnholtz-Sloan, Melissa Bondy, Michele L Cote, Ellen Funkhouser, Patricia G Moorman, Lauren C Peres, Edward S Peters, Ann G Schwartz, Paul D Terry, Xin-Qun Wang, Temitope O Keku, Cathrine Hoyo, Andrew Berchuck, Dale P Sandler, Jack A Taylor, Katie M O'Brien, Digna R Velez Edwards, Todd L Edwards, Alicia Beeghly-Fadiel, Nicolas Wentzensen, Celeste Leigh Pearce, Anna H Wu, Alice S Whittemore, Valerie McGuire, Weiva Sieh, Joseph H Rothstein, Francesmary Modugno, Roberta Ness, Kirsten Moysich, Mary Anne Rossing, Jennifer A Doherty, Thomas A Sellers, Jennifer B Permuth-Way, Alvaro N Monteiro, Douglas A Levine, Veronica Wendy Setiawan, Christopher A Haiman, Loic Lemarchand, Lynne R Wilkens, Beth Y Karlan, Usha Menon, Susan Ramus, Simon Gayther, Aleksandra Gentry-Maharaj, Kathryn L Terry, Daniel W Cramer, Ellen L Goode, Melissa C Larson, Scott H Kaufmann, Rikki Cannioto, Kunle Odunsi, John L Etter, Ruea-Yea Huang, Marcus Q Bernardini, Alicia A Tone, Taymaa May, Marc T Goodman, Pamela J Thompson, Michael E Carney, Shelley S Tworoger, Elizabeth M Poole, Diether Lambrechts, Ignace Vergote, Adriaan Vanderstichele, Els Van Nieuwenhuysen, Hoda Anton-Culver, Argyrios Ziogas, James D Brenton, Line Bjorge, Helga B Salvensen, Lambertus A Kiemeney, Leon FAG Massuger, Tanja Pejovic, Amanda Bruegl, Melissa Moffitt, Linda Cook, Nhu D Le, Angela Brooks-Wilson, Linda E Kelemen, Paul DP Pharoah, Honglin Song, Ian Campbell, Diana Eccles, Anna DeFazio, Catherine J Kennedy, Joellen M Schildkraut
Sep 17, 2019
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Physical activity and risks of breast and colorectal cancer
Physical activity has been associated with lower risks of breast and colorectal cancer in epidemiological studies; however, it is unknown if these associations are causal or confounded. In two-sample Mendelian randomisation...
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Physical activity and risks of breast and colorectal cancer
Physical activity has been associated with lower risks of breast and colorectal cancer in epidemiological studies; however, it is unknown if these associations are causal or confounded. In two-sample Mendelian randomisation...
Published by: Nature Communications
Physical activity and risks of breast and colorectal cancer
Abstract: Physical activity has been associated with lower risks of breast and colorectal cancer in epidemiological studies; however, it is unknown if these associations are causal or confounded. In two-sample Mendelian...
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Genetic architectures of proximal and distal colorectal cancer are partly distinct.
Jeroen R Huyghe, Tabitha A Harrison, Stephanie A Bien, Heather Hampel, Jane C Figueiredo, Stephanie L Schmit, David V Conti, Sai Chen, Conghui Qu, Yi Lin, Richard Barfield, John A Baron, Amanda J Cross, Brenda Diergaarde, David Duggan, Sophia Harlid, Liher Imaz, Hyun Min Kang, David M Levine, Vittorio Perduca, Aurora Perez-Cornago, Lori C Sakoda, Fredrick R Schumacher, Martha L Slattery, Amanda E Toland, Fränzel JB van Duijnhoven, Bethany Van Guelpen, Antonio Agudo, Demetrius Albanes, M Henar Alonso, Kristin Anderson, Coral Arnau-Collell, Volker Arndt, Barbara L Banbury, Michael C Bassik, Sonja I Berndt, Stéphane Bézieau, D Timothy Bishop, Juergen Boehm, Heiner Boeing, Marie-Christine Boutron-Ruault, Hermann Brenner, Stefanie Brezina, Stephan Buch, Daniel D Buchanan, Andrea Burnett-Hartman, Bette J Caan, Peter T Campbell, Prudence R Carr, Antoni Castells, Sergi Castellví-Bel, Andrew T Chan, Jenny Chang-Claude, Stephen J Chanock, Keith R Curtis, Albert de la Chapelle, Douglas F Easton, Dallas R English, Edith JM Feskens, Manish Gala, Steven J Gallinger, W James Gauderman, Graham G Giles, Phyllis J Goodman, William M Grady, John S Grove, Andrea Gsur, Marc J Gunter, Robert W Haile, Jochen Hampe, Michael Hoffmeister, John L Hopper, Wan-Ling Hsu, Wen-Yi Huang, Thomas J Hudson, Mazda Jenab, Mark A Jenkins, Amit D Joshi, Temitope O Keku, Charles Kooperberg, Tilman Kühn, Sébastien Küry, Loic Le Marchand, Flavio Lejbkowicz, Christopher I Li, Li Li, Wolfgang Lieb, Annika Lindblom, Noralane M Lindor, Satu Männistö, Sanford D Markowitz, Roger L Milne, Lorena Moreno, Neil Murphy, Rami Nassir, Kenneth Offit, Shuji Ogino, Salvatore Panico, Patrick S Parfrey, Rachel Pearlman, Paul DP Pharoah, Amanda I Phipps, Elizabeth A Platz, John D Potter, Ross L Prentice, Lihong Qi, Leon Raskin, Gad Rennert, Hedy S Rennert, Elio Riboli, Clemens Schafmayer, Robert E Schoen, Daniela Seminara, Mingyang Song, Yu-Ru Su, Catherine M Tangen, Stephen N Thibodeau, Duncan C Thomas, Antonia Trichopoulou, Cornelia M Ulrich, Kala Visvanathan, Pavel Vodicka, Ludmila Vodickova, Veronika Vymetalkova, Korbinian Weigl, Stephanie J Weinstein, Emily White, Alicja Wolk, Michael O Woods, Anna H Wu, Goncalo R Abecasis, Deborah A Nickerson, Peter C Scacheri, Anshul Kundaje, Graham Casey, Stephen B Gruber, Li Hsu, Victor Moreno, Richard B Hayes, Polly A Newcomb, Ulrike Peters
Mar 02, 2021
OBJECTIVE: An understanding of the etiologic heterogeneity of colorectal cancer (CRC) is critical for improving precision prevention, including individualized screening recommendations and the discovery of novel drug targets and...
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Cumulative Burden of Colorectal Cancer-Associated Genetic Variants Is More Strongly Associated With Early-Onset vs Late-Onset Cancer.
Alexi N Archambault, Yu-Ru Su, Jihyoun Jeon, Minta Thomas, Yi Lin, David V Conti, Aung Ko Win, Lori C Sakoda, Iris Lansdorp-Vogelaar, Elisabeth FP Peterse, Ann G Zauber, David Duggan, Andreana N Holowatyj, Jeroen R Huyghe, Hermann Brenner, Michelle Cotterchio, Stéphane Bézieau, Stephanie L Schmit, Christopher K Edlund, Melissa C Southey, Robert J Macinnis, Peter T Campbell, Jenny Chang-Claude, Martha L Slattery, Andrew T Chan, Amit D Joshi, Mingyang Song, Yin Cao, Michael O Woods, Emily White, Stephanie J Weinstein, Cornelia M Ulrich, Michael Hoffmeister, Stephanie A Bien, Tabitha A Harrison, Jochen Hampe, Christopher I Li, Clemens Schafmayer, Kenneth Offit, Paul D Pharoah, Victor Moreno, Annika Lindblom, Alicja Wolk, Anna H Wu, Li Li, Marc J Gunter, Andrea Gsur, Temitope O Keku, Rachel Pearlman, D Timothy Bishop, Sergi Castellví-Bel, Leticia Moreira, Pavel Vodicka, Ellen Kampman, Graham G Giles, Demetrius Albanes, John A Baron, Sonja I Berndt, Stefanie Brezina, Stephan Buch, Daniel D Buchanan, Antonia Trichopoulou, Gianluca Severi, María-Dolores Chirlaque, Maria-José Sánchez, Domenico Palli, Tilman Kühn, Neil Murphy, Amanda J Cross, Andrea N Burnett-Hartman, Stephen J Chanock, Albert de la Chapelle, Douglas F Easton, Faye Elliott, Dallas R English, Edith JM Feskens, Liesel M Fitzgerald, Phyllis J Goodman, John L Hopper, Thomas J Hudson, David J Hunter, Eric J Jacobs, Corinne E Joshu, Sébastien Küry, Sanford D Markowitz, Roger L Milne, Elizabeth A Platz, Gad Rennert, Hedy S Rennert, Fredrick R Schumacher, Robert S Sandler, Daniela Seminara, Catherine M Tangen, Stephen N Thibodeau, Amanda E Toland, Franzel JB van Duijnhoven, Kala Visvanathan, Ludmila Vodickova, John D Potter, Satu Männistö, Korbinian Weigl, Jane Figueiredo, Vicente Martín, Susanna C Larsson, Patrick S Parfrey, Wen-Yi Huang, Heinz-Josef Lenz, Jose E Castelao, Manuela Gago-Dominguez, Victor Muñoz-Garzón, Christoph Mancao, Christopher A Haiman, Lynne R Wilkens, Erin Siegel, Elizabeth Barry, Ban Younghusband, Bethany Van Guelpen, Sophia Harlid, Anne Zeleniuch-Jacquotte, Peter S Liang, Mengmeng Du, Graham Casey, Noralane M Lindor, Loic Le Marchand, Steven J Gallinger, Mark A Jenkins, Polly A Newcomb, Stephen B Gruber, Robert E Schoen, Heather Hampel, Douglas A Corley, Li Hsu, Ulrike Peters, Richard B Hayes
Dec 12, 2019
BACKGROUND & AIMS: Early-onset colorectal cancer (CRC, in persons younger than 50 years old) is increasing in incidence; yet, in the absence of a family history of CRC, this population lacks harmonized recommendations for...
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Discovery of common and rare genetic risk variants for colorectal cancer.
Jeroen R Huyghe, Stephanie A Bien, Tabitha A Harrison, Hyun Min Kang, Sai Chen, Stephanie L Schmit, David V Conti, Conghui Qu, Jihyoun Jeon, Christopher K Edlund, Peyton Greenside, Michael Wainberg, Fredrick R Schumacher, Joshua D Smith, David M Levine, Sarah C Nelson, Nasa A Sinnott-Armstrong, Demetrius Albanes, M Henar Alonso, Kristin Anderson, Coral Arnau-Collell, Volker Arndt, Christina Bamia, Barbara L Banbury, John A Baron, Sonja I Berndt, Stéphane Bézieau, D Timothy Bishop, Juergen Boehm, Heiner Boeing, Hermann Brenner, Stefanie Brezina, Stephan Buch, Daniel D Buchanan, Andrea Burnett-Hartman, Katja Butterbach, Bette J Caan, Peter T Campbell, Christopher S Carlson, Sergi Castellví-Bel, Andrew T Chan, Jenny Chang-Claude, Stephen J Chanock, Maria-Dolores Chirlaque, Sang Hee Cho, Charles M Connolly, Amanda J Cross, Katarina Cuk, Keith R Curtis, Albert de la Chapelle, Kimberly F Doheny, David Duggan, Douglas F Easton, Sjoerd G Elias, Faye Elliott, Dallas R English, Edith JM Feskens, Jane C Figueiredo, Rocky Fischer, Liesel M Fitzgerald, David Forman, Manish Gala, Steven Gallinger, W James Gauderman, Graham G Giles, Elizabeth Gillanders, Jian Gong, Phyllis J Goodman, William M Grady, John S Grove, Andrea Gsur, Marc J Gunter, Robert W Haile, Jochen Hampe, Heather Hampel, Sophia Harlid, Richard B Hayes, Philipp Hofer, Michael Hoffmeister, John L Hopper, Wan-Ling Hsu, Wen-Yi Huang, Thomas J Hudson, David J Hunter, Gemma Ibañez-Sanz, Gregory E Idos, Roxann Ingersoll, Rebecca D Jackson, Eric J Jacobs, Mark A Jenkins, Amit D Joshi, Corinne E Joshu, Temitope O Keku, Timothy J Key, Hyeong Rok Kim, Emiko Kobayashi, Laurence N Kolonel, Charles Kooperberg, Tilman Kühn, Sébastien Küry, Sun-Seog Kweon, Susanna C Larsson, Cecelia A Laurie, Loic Le Marchand, Suzanne M Leal, Soo Chin Lee, Flavio Lejbkowicz, Mathieu Lemire, Christopher I Li, Li Li, Wolfgang Lieb, Yi Lin, Annika Lindblom, Noralane M Lindor, Hua Ling, Tin L Louie, Satu Männistö, Sanford D Markowitz, Vicente Martín, Giovanna Masala, Caroline E McNeil, Marilena Melas, Roger L Milne, Lorena Moreno, Neil Murphy, Robin Myte, Alessio Naccarati, Polly A Newcomb, Kenneth Offit, Shuji Ogino, N Charlotte Onland-Moret, Barbara Pardini, Patrick S Parfrey, Rachel Pearlman, Vittorio Perduca, Paul DP Pharoah, Mila Pinchev, Elizabeth A Platz, Ross L Prentice, Elizabeth Pugh, Leon Raskin, Gad Rennert, Hedy S Rennert, Elio Riboli, Miguel Rodríguez-Barranco, Jane Romm, Lori C Sakoda, Clemens Schafmayer, Robert E Schoen, Daniela Seminara, Mitul Shah, Tameka Shelford, Min-Ho Shin, Katerina Shulman, Sabina Sieri, Martha L Slattery, Melissa C Southey, Zsofia K Stadler, Christa Stegmaier, Yu-Ru Su, Catherine M Tangen, Stephen N Thibodeau, Duncan C Thomas, Sushma S Thomas, Amanda E Toland, Antonia Trichopoulou, Cornelia M Ulrich, David J Van Den Berg, Franzel JB van Duijnhoven, Bethany Van Guelpen, Henk van Kranen, Joseph Vijai, Kala Visvanathan, Pavel Vodicka, Ludmila Vodickova, Veronika Vymetalkova, Korbinian Weigl, Stephanie J Weinstein, Emily White, Aung Ko Win, C Roland Wolf, Alicja Wolk, Michael O Woods, Anna H Wu, Syed H Zaidi, Brent W Zanke, Qing Zhang, Wei Zheng, Peter C Scacheri, John D Potter, Michael C Bassik, Anshul Kundaje, Graham Casey, Victor Moreno, Goncalo R Abecasis, Deborah A Nickerson, Stephen B Gruber, Li Hsu, Ulrike Peters
Dec 11, 2018
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