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Body Composition changes after Testosterone Replacement Therapy following Spinal Cord Injury and Aging
CONTEXT: Hypogonadism is a male clinical condition in which the body does not produce enough testosterone. Testosterone plays a key role in maintaining body composition, bone mineral density, sexual function, mood...
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Body Composition changes after Testosterone Replacement Therapy following Spinal Cord Injury and Aging
CONTEXT: Hypogonadism is a male clinical condition in which the body does not produce enough testosterone. Testosterone plays a key role in maintaining body composition, bone mineral density, sexual function, mood...
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Circularization of flavivirus genomic RNA inhibits de novo translation initiation.
Members of the Flaviviridae family, including dengue virus (DENV) and yellow fever virus, cause serious disease in humans, whilst maternal infection with Zika virus (ZIKV) can induce microcephaly in newborns. Following...
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Stress-induced protein disaggregation in the endoplasmic reticulum catalysed by BiP.
Protein synthesis is supported by cellular machineries that ensure polypeptides fold to their native conformation, whilst eliminating misfolded, aggregation prone species. Protein aggregation underlies pathologies including...
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Phylogeography of Lyme borreliosis-group spirochetes and methicillin-resistant <em>Staphylococcus aureus</em>
Multilocus sequence typing (MLST) and multilocus sequence analysis (MLSA) have revolutionized understanding the global epidemiology of many medically relevant bacteria utilizing a number, mostly seven, of housekeeping genes. A...
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Non-axisymmetric complete flow conditioning gauzes
Abstract: This paper presents a novel methodology for the design of a gauze that produces distributions of stagnation pressure, swirl angle, pitch angle and turbulence intensity, tailored in both the radial and circumferential...
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Non-axisymmetric complete flow conditioning gauzes
Abstract: This paper presents a novel methodology for the design of a gauze that produces distributions of stagnation pressure, swirl angle, pitch angle and turbulence intensity, tailored in both the radial and circumferential...
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Protein amino acid composition
Large brains relative to body size represent an evolutionarily costly adaptation as they are metabolically expensive and demand substantial amounts of time to reach structural and functional maturity thereby exacerbating...
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Phylogeography of Lyme borreliosis-group spirochetes and methicillin-resistant <em>Staphylococcus aureus</em>
Multilocus sequence typing (MLST) and multilocus sequence analysis (MLSA) have revolutionized understanding the global epidemiology of many medically relevant bacteria utilizing a number, mostly seven, of housekeeping genes. A...
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Protein amino acid composition
Large brains relative to body size represent an evolutionarily costly adaptation as they are metabolically expensive and demand substantial amounts of time to reach structural and functional maturity thereby exacerbating...
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Revisiting the Impact of Local Leptin Signaling in Folliculogenesis and Oocyte Maturation in Obese Mothers
The complex nature of folliculogenesis regulation accounts for its susceptibility to maternal physiological fitness. In obese mothers, progressive expansion of adipose tissue culminates with severe hyperestrogenism and...
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Materials Formed by Combining Inorganic Glasses and Metal-Organic Frameworks.
Here, we propose the combination of glassy or crystalline metal-organic frameworks (MOFs) with inorganic glasses to create novel hybrid composites and blends.The motivation behind this new composite approach is to improve the...
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Increased brain size in mammals is associated with size variations in gene families with cell signalling, chemotaxis and immune-related functions
Genomic determinants underlying increased encephalization across mammalian lineages are unknown. Whole genome comparisons have revealed large and frequent changes in the size of gene families, and it has been proposed that these...
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Increased brain size in mammals is associated with size variations in gene families with cell signalling, chemotaxis and immune-related functions
Genomic determinants underlying increased encephalization across mammalian lineages are unknown. Whole genome comparisons have revealed large and frequent changes in the size of gene families, and it has been proposed that these...
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