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Results: 454
Evaluation of an explanted porcine skin model to investigate infection with the dermatophyte Trichophyton rubrum.
Dermatophytosis is a fungal infection of skin, hair and nails, and the most frequently found causative agent is Trichophyton rubrum. The disease is very common and often recurring, and it is therefore difficult to eradicate. To...
Antifungals Dermatophytes Explanted porcine skin Skin infection model Trichophyton rubrum /dk/atira/pure/subjectarea/asjc/2400/2404 name=Microbiology /dk/atira/pure/subjectarea/asjc/2400/2402 name=Applied Microbiology and Biotechnology /dk/atira/pure/subjectarea/asjc/1100/1102 name=Agronomy and Crop Science /dk/atira/pure/subjectarea/asjc/3400/3401 name=veterinary (miscalleneous) /dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_being name=SDG 3 - Good Health and Well-being
Evaluation of an explanted porcine skin model to investigate infection with the dermatophyte Trichophyton rubrum.
Dermatophytosis is a fungal infection of skin, hair and nails, and the most frequently found causative agent is Trichophyton rubrum. The disease is very common and often recurring, and it is therefore difficult to eradicate. To...
Antifungals Dermatophytes Explanted porcine skin Skin infection model Trichophyton rubrum /dk/atira/pure/subjectarea/asjc/2400/2404 name=Microbiology /dk/atira/pure/subjectarea/asjc/2400/2402 name=Applied Microbiology and Biotechnology /dk/atira/pure/subjectarea/asjc/1100/1102 name=Agronomy and Crop Science /dk/atira/pure/subjectarea/asjc/3400/3401 name=veterinary (miscalleneous) /dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_being name=SDG 3 - Good Health and Well-being
Development of refractoriness of ho-1 induction to a second treatment with uva radiation and the involvement of nrf2 in human skin fibroblasts
Julia Li Zhong, Chintan M. Raval, Muhammad Farrukh Nisar, ChunXiang Bian, Jin Zhang, Li Yang, Rex M. Tyrrell
Nov 01, 2014
UVA treatment of cultured human skin fibroblasts (FEK4) has been shown previously to reduce transcriptional activation of heme oxygenase 1 (HO-1) following a second dose of UVA radiation, a phenomenon known as refractoriness....
A microtiter plate-based quantitative method to monitor the growth rate of dermatophytes and test antifungal activity
Dermatophytosis is one of the most common superficial fungal infections, which is mainly caused by filamentous fungi such as Trichophyton species. A challenging aspect in dermatophyte research is the lack of a straightforward...
A microtiter plate-based quantitative method to monitor the growth rate of dermatophytes and test antifungal activity
Dermatophytosis is one of the most common superficial fungal infections, which is mainly caused by filamentous fungi such as Trichophyton species. A challenging aspect in dermatophyte research is the lack of a straightforward...
Frequent transmission of the Mycobacterium tuberculosis Beijing lineage and positive selection for the EsxW Beijing variant in Vietnam.
Kathryn E Holt, Paul McAdam, Phan Vuong Khac Thai, Nguyen Thuy Thuong Thuong, Dang Thi Minh Ha, Nguyen Ngoc Lan, Nguyen Huu Lan, Nguyen Thi Quynh Nhu, Hoang Thanh Hai, Vu Thi Ngoc Ha, Guy Thwaites, David J Edwards, Artika P Nath, Kym Pham, David B Ascher, Jeremy Farrar, Chiea Chuen Khor, Yik Ying Teo, Michael Inouye, Maxine Caws, Sarah J Dunstan
Sep 05, 2018
To examine the transmission dynamics of Mycobacterium tuberculosis (Mtb) isolated from tuberculosis patients in Ho Chi Minh City, Vietnam, we sequenced the whole genomes of 1,635 isolates and compared these with 3,144 isolates...
Development of refractoriness of ho-1 induction to a second treatment with uva radiation and the involvement of nrf2 in human skin fibroblasts
Julia Li Zhong, Chintan M. Raval, Muhammad Farrukh Nisar, ChunXiang Bian, Jin Zhang, Li Yang, Rex M. Tyrrell
Nov 01, 2014
UVA treatment of cultured human skin fibroblasts (FEK4) has been shown previously to reduce transcriptional activation of heme oxygenase 1 (HO-1) following a second dose of UVA radiation, a phenomenon known as refractoriness....
A Bayesian analysis of the association between Leukotriene A4 Hydrolase genotype and survival in tuberculous meningitis.
Laura Whitworth, Jacob Coxon, Arjan van Laarhoven, Nguyen Thuy Thuong Thuong, Sofiati Dian, Bachti Alisjahbana, Ahmad Rizal Ganiem, Reinout van Crevel, Guy E Thwaites, Mark Troll, Paul H Edelstein, Roger Sewell, Lalita Ramakrishnan
Feb 04, 2021
Tuberculous meningitis has high mortality, linked to excessive inflammation. However, adjunctive anti-inflammatory corticosteroids reduce mortality by only 30%, suggesting that inflammatory pathophysiology causes only a subset...
A Bayesian analysis of the association between Leukotriene A4 Hydrolase genotype and survival in tuberculous meningitis
Laura Whitworth, Jacob Coxon, Arjan van Laarhoven, Nguyen Thuy Thuong Thuong, Sofiati Dian, Bachti Alisjahbana, Ahmad Rizal Ganiem, Reinout van Crevel, Guy E Thwaites, Mark Troll, Paul H Edelstein, Roger Sewell, Lalita Ramakrishnan
Jan 08, 2021
Tuberculous meningitis has high mortality, linked to excessive inflammation. However, adjunctive anti-inflammatory corticosteroids reduce mortality by only 30%, suggesting that inflammatory pathophysiology causes only a subset...
Elevated cerebrospinal fluid cytokine levels in tuberculous meningitis predict survival in response to dexamethasone.
Laura J Whitworth, Rajan Troll, Antonio J Pagán, Francisco J Roca, Paul H Edelstein, Mark Troll, David M Tobin, Nguyen Hoan Phu, Nguyen Duc Bang, Guy E Thwaites, Nguyen Thuy Thuong Thuong, Roger F Sewell, Lalita Ramakrishnan
Mar 18, 2021
Adjunctive treatment with antiinflammatory corticosteroids like dexamethasone increases survival in tuberculosis meningitis. Dexamethasone responsiveness associates with a C/T variant in Leukotriene A4 Hydrolase (LTA4H), which...
Retrospective analysis assessing the spatial and temporal distribution of paediatric acute respiratory tract infections in Ho Chi Minh City, Vietnam.
Nhan Thi Ho, Corinne Thompson, Le Nguyen Thanh Nhan, Hoang Minh Tu Van, Nguyen Thanh Dung, Phuc Tran My, Vo Minh Quang, Ngo Ngoc Quang Minh, Tran Anh Tuan, Nguyen Thanh Hung, Ha Manh Tuan, Nguyen Van Vinh Chau, Marcel Wolbers, Guy E Thwaites, Marc Choisy, Stephen Baker
Apr 10, 2019
BACKGROUND: Acute respiratory tract infections (ARIs) are the leading cause of morbidity and mortality in young children in low/middle-income countries. Using routine hospital data, we aimed to examine the spatial distribution...
acute respiratory infections lower respiratory infections Pediatrics spatial distribution Temporal patterns upper respiratory infections Acute Disease Adolescent Child Child Preschool Female Hospitalization Hospitals Pediatric Humans Incidence Infant Infant Newborn Male Respiratory Tract Infections Retrospective Studies Risk Factors Seasons Spatio-Temporal Analysis Vietnam weather
CDK2 limits the highly energetic secretory program of mature β cells by restricting PEP cycle-dependent KATP channel closure.
Sophia M Sdao, Thuong Ho, Chetan Poudel, Hannah R Foster, Elizabeth R De Leon, Melissa T Adams, Ji-Hyeon Lee, Barak Blum, Sushil G Rane, Matthew J Merrins
Mar 25, 2021
Hallmarks of mature β cells are restricted proliferation and a highly energetic secretory state. Paradoxically, cyclin-dependent kinase 2 (CDK2) is synthesized throughout adulthood, its cytosolic localization raising the...
Biphasic pattern in the effect of severe measles infection; the difference between additive and multiplicative scale.
BACKGROUND: Infection with measles virus (MeV) causes immunosuppression and increased susceptibility to other infectious diseases. Only few studies reported a duration of immunosuppression, with varying results. We investigated...
Biphasic pattern in the effect of severe measles infection; the difference between additive and multiplicative scale.
BACKGROUND: Infection with measles virus (MeV) causes immunosuppression and increased susceptibility to other infectious diseases. Only few studies reported a duration of immunosuppression, with varying results. We investigated...
Technological Factors Affecting Communication Quality at Ho Chi Minh City University of Industry and Trade
In the current era of technological explosion, applications are widely adopted and continuously improved, significantly impacting the education sector and creating a high demand for training within educational institutions. This...
Published by: IGI Global Scientific Publishing
Clinical and laboratory factors associated with neonatal sepsis mortality at a major Vietnamese children's hospital.
Nguyen Duc Toan, Thomas C Darton, Nguyen Hoang Thien Huong, Le Thanh Hoang Nhat, To Nguyen Thi Nguyen, Ha Thanh Tuyen, Le Quoc Thinh, Nguyen Kien Mau, Pham Thi Thanh Tam, Cam Ngoc Phuong, Le Nguyen Thanh Nhan, Ngo Ngoc Quang Minh, Ngo Minh Xuan, Tang Chi Thuong, Nguyen Thanh Hung, Christine Boinett, Stephen Reece, Abhilasha Karkey, Jeremy N Day, Stephen Baker
Apr 17, 2023
Sepsis is a major cause of neonatal mortality and children born in low- and middle-income countries (LMICs) are at greater risk of severe neonatal infections than those in higher-income countries. Despite this disparity, there...
Published by: PLOS global public health
Prognostic models for 9 month mortality in tuberculous meningitis
Le Thi Phuong Thao, A Dorothee Heemskerk, Ronald B Geskus, Nguyen Thi Hoang Mai, Dang Thi Minh Ha, Tran Thi Hong Chau, Nguyen Hoan Phu, Nguyen Van Vinh Chau, Maxine Caws, Nguyen Huu Lan, Do Dang Anh Thu, Nguyen Thuy Thuong Thuong, Jeremy Day, Jeremy J Farrar, M Estee Torok, Nguyen Duc Bang, Guy E Thwaites, Marcel Wolbers
May 02, 2018
Incidence of heterotopic ossification following hip arthroscopy is low
PURPOSE: This scoping review aims to map and summarise the available literature on heterotopic ossification (HO) following hip arthroscopy, with particular focus on incidence, distribution as per Brooker classification, efficacy...
Clinical and laboratory factors associated with neonatal sepsis mortality at a major Vietnamese children's hospital.
Nguyen Duc Toan, Thomas C Darton, Nguyen Hoang Thien Huong, Le Thanh Hoang Nhat, To Nguyen Thi Nguyen, Ha Thanh Tuyen, Le Quoc Thinh, Nguyen Kien Mau, Pham Thi Thanh Tam, Cam Ngoc Phuong, Le Nguyen Thanh Nhan, Ngo Ngoc Quang Minh, Ngo Minh Xuan, Tang Chi Thuong, Nguyen Thanh Hung, Christine Boinett, Stephen Reece, Abhilasha Karkey, Jeremy N Day, Stephen Baker
Sep 02, 2022
Sepsis is a major cause of neonatal mortality and children born in low- and middle-income countries (LMICs) are at greater risk of severe neonatal infections than those in higher-income countries. Despite this disparity, there...
Patient Safety Infant Mortality Hematology Sepsis Pediatric Clinical Research Infectious Diseases Perinatal Period - Conditions Originating in Perinatal Period 4.1 Discovery and preclinical testing of markers and technologies 4 Detection screening and diagnosis Infection Inflammatory and immune system 3 Good Health and Well Being
Clinical features, antimicrobial susceptibility patterns and genomics of bacteria causing neonatal sepsis in a children's hospital in Vietnam
Nguyen Duc Toan, Thomas C Darton, Christine J Boinett, James I Campbell, Abhilasha Karkey, Evelyne Kestelyn, Le Quoc Thinh, Nguyen Kien Mau, Pham Thi Thanh Tam, Le Nguyen Thanh Nhan, Ngo Ngoc Quang Minh, Cam Ngoc Phuong, Nguyen Thanh Hung, Ngo Minh Xuan, Tang Chi Thuong, Stephen Baker
Apr 10, 2019
INTRODUCTION: The clinical syndrome of neonatal sepsis, comprising signs of infection, septic shock and organ dysfunction in infants ≤4 weeks of age, is a frequent sequel to bloodstream infection and mandates urgent...
Antimicrobial resistance clinical features Genomics neonates outcomes Sepsis Anti-Infective Agents Bacteria Drug Resistance Multiple Bacterial Female Hospitals Pediatric Humans Infant Infant Newborn Linear Models Male Microbial Sensitivity Tests Neonatal Sepsis Phylogeny Prospective Studies Research Design Vietnam whole genome sequencing
Heterotopic ossification in mice overexpressing Bmp2 in Tie2+ lineages.
Belén Prados, Raquel Del Toro, Donal MacGrogan, Paula Gómez-Apiñániz, Tania Papoutsi, Pura Muñoz-Cánoves, Simón Méndez-Ferrer, José Luis de la Pompa
Sep 08, 2021
Bone morphogenetic protein (Bmp) signaling is critical for organismal development and homeostasis. To elucidate Bmp2 function in the vascular/hematopoietic lineages we generated a new transgenic mouse line in which ectopic Bmp2...
Animals Aortic Valve Bone Marrow Transplantation Bone Morphogenetic Protein 2 Calcinosis Cell Lineage Chondrogenesis Endothelial Cells Hematopoiesis Hematopoietic Stem Cells Kaplan-Meier Estimate Mice Inbred C57BL Mice Transgenic Muscle Cells Ossification Heterotopic Osteogenesis Receptor TIE-2 Tomography X-Ray Computed
The effect of xanthine oxidase and hypoxanthine on the permeability of red cells from patients with sickle cell anemia.
Red cells from patients with sickle cell anemia (SCA) are under greater oxidative challenge than those from normal individuals. We postulated that oxidants generated by xanthine oxidase (XO) and hypoxanthine (HO) contribute to...
The Lantern Vol. 6, No. 1, December 1937
Roberta Byron, Ernest Muller, Mabel B. Ditter, Elizabeth M. Seidle, Jane Poling, Frank J. Tornetta, Vernon D. Groff, Edward L. French, Evelyn Huber, Robert B. Peck, Dorothy Kinsey Shisler, C. Kenneth Snyder, Robert E. Yoh, Eli Broidy, Ruth Grauert, Charles Steinmetz
Jan 01, 0001
After Thinking Things Over Ho! Ho! The Mistletoe! Unrealized Dreams Two Preeminent Victorians The Thing Progression It Wasn't in the Lines He Was the Most Perfect Man College (C)lasses Robins and Roses The...
Ursinus College Collegeville Pennsylvania Lantern Literary Magazine poetry fiction Creative Nonfiction Christmas Oscar Wilde The Mikado W. S. Gilbert Arthur Sullivan Reginald S. Sibbald drama Louis Pasteur newspapers Censorship propaganda Winslow Homer Maine Maurice Evans King Richard II Isle of Man Manxmen Arts and Humanities Creative Writing fiction illustration Nonfiction poetry
Published by: Ursinus College
Macrophages are exploited from an innate wound healing response to facilitate cancer metastasis.
Tamara Muliaditan, Jonathan Caron, Mary Okesola, James W Opzoomer, Paris Kosti, Mirella Georgouli, Peter Gordon, Sharanpreet Lall, Desislava M Kuzeva, Luisa Pedro, Jacqueline D Shields, Cheryl E Gillett, Sandra S Diebold, Victoria Sanz-Moreno, Tony Ng, Esther Hoste, James N Arnold
Nov 06, 2018
Tumour-associated macrophages (TAMs) play an important role in tumour progression, which is facilitated by their ability to respond to environmental cues. Here we report, using murine models of breast cancer, that TAMs...
Animals Breast Neoplasms Cell Line Tumor Cell Survival Collagen Cytokines Endopeptidases Female Gelatinases Gene Expression Regulation Neoplastic Heme Oxygenase-1 Humans Interleukin-6 MACROPHAGES Membrane Proteins Mice Mice Inbred BALB C Mice Mutant Strains Neoplasm Metastasis Phenotype Prognosis Serine Endopeptidases Skin Tumor Microenvironment Wound Healing
Heterotopic ossification in mice overexpressing Bmp2 in Tie2+ lineages
Belén Prados, Raquel Del Toro, Donal MacGrogan, Paula Gómez-Apiñániz, Tania Papoutsi, Pura Muñoz-Cánoves, Simón Méndez-Ferrer, José Luis de la Pompa
Jul 28, 2021
Abstract: Bone morphogenetic protein (Bmp) signaling is critical for organismal development and homeostasis. To elucidate Bmp2 function in the vascular/hematopoietic lineages we generated a new transgenic mouse line in which...
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