Search
Results: 47
Structural basis of synaptic vesicle assembly promoted by α-synuclein.
Giuliana Fusco, Tillmann Pape, Amberley D Stephens, Pierre Mahou, Ana Rita Costa, Clemens F Kaminski, Gabriele S Kaminski Schierle, Michele Vendruscolo, Gianluigi Veglia, Christopher M Dobson, Alfonso De Simone
Mar 04, 2020
α-synuclein (αS) is an intrinsically disordered protein whose fibrillar aggregates are the major constituents of Lewy bodies in Parkinson's disease. Although the specific function of αS is still unclear, a general consensus is...
Distilling reliable remedies
Tillmann Taape
Sep 26, 2016
Molecular HLA mismatching for prediction of primary humoral alloimmunity and graft function deterioration in paediatric kidney transplantation
Dissecting the phenotypic heterogeneity in sensory features in autism spectrum disorder
J Tillmann, M Uljarevic, D Crawley, G Dumas, E Loth, D Murphy, J Buitelaar, T Charman, AIMS-2-TRIALS LEAP group
Oct 26, 2020
BACKGROUND: Heterogeneity in the phenotypic presentation of autism spectrum disorder (ASD) is apparent in the profile and the severity of sensory features. Here, we applied factor mixture modelling (FMM) to test a...
Cloud condensation nuclei activity, droplet growth kinetics, and hygroscopicity of biogenic and anthropogenic secondary organic aerosol (SOA)
DF Zhao, A Buchholz, B Kortner, P Schlag, F Rubach, H Fuchs, A Kiendler-Scharr, R Tillmann, A Wahner, K Watne, M Hallquist, JM Flores, Y Rudich, K Kristensen, AMK Hansen, M Glasius, I Kourtchev, M Kalberer, TF Mentel
Oct 13, 2016
How do core autism traits and associated symptoms relate to quality of life? Findings from the Longitudinal European Autism Project.
Bethany Fm Oakley, Julian Tillmann, Jumana Ahmad, Daisy Crawley, Antonia San José Cáceres, Rosemary Holt, Tony Charman, Tobias Banaschewski, Jan Buitelaar, Emily Simonoff, Declan Murphy, Eva Loth
Apr 10, 2021
Previous studies suggest that some autistic individuals report lower satisfaction, or well-being, with different aspects of everyday life than those without autism. It is unclear whether this might be partly explained by...
Gray matter covariations and core symptoms of autism
Ting Mei, Alberto Llera, Dorothea L. Floris, Natalie J. Forde, Julian Tillmann, Sarah Durston, Carolin Moessnang, Tobias Banaschewski, Rosemary J. Holt, Simon Baron-Cohen, Annika Rausch, Eva Loth, Flavio Dell’Acqua, Tony Charman, Declan G. M. Murphy, Christine Ecker, Christian F. Beckmann, Jan K. Buitelaar
Oct 31, 2020
Exploring the neuropsychiatric spectrum using high-content functional analysis of single-cell signaling networks.
Santiago G Lago, Jakub Tomasik, Geertje F van Rees, Jordan M Ramsey, Frieder Haenisch, Jason D Cooper, Jantine A Broek, Paula Suarez-Pinilla, Tillmann Ruland, Bonnie Auyeug, Olya Mikova, Nikolett Kabacs, Volker Arolt, Simon Baron-Cohen, Benedicto Crespo-Facorro, Sabine Bahn
May 09, 2019
Neuropsychiatric disorders overlap in symptoms and share genetic risk factors, challenging their current classification into distinct diagnostic categories. Novel cross-disorder approaches are needed to improve our understanding...
Unique dynamic profiles of social attention in autistic females.
Teresa Del Bianco, Luke Mason, Meng-Chuan Lai, Eva Loth, Julian Tillmann, Tony Charman, Hannah Hayward, Teresa Gleissl, Jan K Buitelaar, Declan GM Murphy, Simon Baron-Cohen, Sven Bölte, Mark H Johnson, Emily JH Jones, EU-AIMS LEAP group
Jun 07, 2022
Understanding the consequences of education inequality on cardiovascular disease
Alice R Carter, Dipender Gill, Neil M Davies, Amy E Taylor, Taavi Tillmann, Julien Vaucher, Robyn E Wootton, Marcus R Munafò, Gibran Hemani, Rainer Malik, Sudha Seshadri, Daniel Woo, Stephen Burgess, George Davey Smith, Michael V Holmes, Ioanna Tzoulaki, Laura D Howe, Abbas Dehghan
Sep 17, 2019
Fractionating autism based on neuroanatomical normative modeling
Mariam Zabihi, Dorothea L. Floris, Seyed Mostafa Kia, Thomas Wolfers, Julian Tillmann, Alberto Llera Arenas, Carolin Moessnang, Tobias Banaschewski, Rosemary Holt, Simon Baron-Cohen, Eva Loth, Tony Charman, Thomas Bourgeron, Declan Murphy, Christine Ecker, Jan K. Buitelaar, Christian F. Beckmann, Andre Marquand
Nov 09, 2020
Evaluation of data imputation strategies in complex, deeply-phenotyped data sets
A Llera, M Brammer, B Oakley, J Tillmann, M Zabihi, JS Amelink, T Mei, T Charman, C Ecker, F Dell'Acqua, T Banaschewski, C Moessnang, S Baron-Cohen, R Holt, S Durston, D Murphy, E Loth, JK Buitelaar, DL Floris, CF Beckmann
Aug 16, 2022
An increasing number of large-scale multi-modal research initiatives has been conducted in the typically developing population, e.g. Dev. Cogn. Neur. 32:43-54, 2018; PLoS Med. 12(3):e1001779, 2015; Elam and Van Essen, Enc. Comp....
Towards robust and replicable sex differences in the intrinsic brain function of autism.
Dorothea L Floris, José OA Filho, Meng-Chuan Lai, Steve Giavasis, Marianne Oldehinkel, Maarten Mennes, Tony Charman, Julian Tillmann, Guillaume Dumas, Christine Ecker, Flavio Dell'Acqua, Tobias Banaschewski, Carolin Moessnang, Simon Baron-Cohen, Sarah Durston, Eva Loth, Declan GM Murphy, Jan K Buitelaar, Christian F Beckmann, Michael P Milham, Adriana Di Martino
Apr 12, 2021
BACKGROUND: Marked sex differences in autism prevalence accentuate the need to understand the role of biological sex-related factors in autism. Efforts to unravel sex differences in the brain organization of autism have...
COVID-19 health and social care access for autistic people
Bethany Oakley, Julian Tillmann, Amber Ruigrok, Aurélie Baranger, Christian Takow, Tony Charman, Emily Jones, James Cusack, Mary Doherty, Pierre Violland, Agnieszka Wroczyńska, Emily Simonoff, Jan K Buitelaar, Louise Gallagher, Declan GM Murphy, AIMS-2-TRIALS ECRAN & the AIMS-2-TRIALS Consortium
Jun 18, 2021
BACKGROUND: The global COVID-19 pandemic has had an unprecedented impact on European health and social care systems, with demands on testing, hospital and intensive care capacity exceeding available resources in many regions....
Excitatory/inhibitory imbalance in autism
Viola Hollestein, Geert Poelmans, Natalie J Forde, Christian F Beckmann, Christine Ecker, Caroline Mann, Tim Schäfer, Carolin Moessnang, Sarah Baumeister, Tobias Banaschewski, Thomas Bourgeron, Eva Loth, Flavio Dell'Acqua, Declan GM Murphy, Nicolaas A Puts, Julian Tillmann, Tony Charman, Emily JH Jones, Luke Mason, Sara Ambrosino, Rosemary Holt, Sven Bölte, Jan K Buitelaar, Jilly Naaijen
Jan 21, 2023
Fractionating autism based on neuroanatomical normative modeling.
Mariam Zabihi, Dorothea L Floris, Seyed Mostafa Kia, Thomas Wolfers, Julian Tillmann, Alberto Llera Arenas, Carolin Moessnang, Tobias Banaschewski, Rosemary Holt, Simon Baron-Cohen, Eva Loth, Tony Charman, Thomas Bourgeron, Declan Murphy, Christine Ecker, Jan K Buitelaar, Christian F Beckmann, Andre Marquand, EU-AIMS LEAP group
Dec 07, 2020
Autism is a complex neurodevelopmental condition with substantial phenotypic, biological, and etiologic heterogeneity. It remains a challenge to identify biomarkers to stratify autism into replicable cognitive or biological...
Gray matter covariations and core symptoms of autism
Ting Mei, Alberto Llera, Dorothea L Floris, Natalie J Forde, Julian Tillmann, Sarah Durston, Carolin Moessnang, Tobias Banaschewski, Rosemary J Holt, Simon Baron-Cohen, Annika Rausch, Eva Loth, Flavio Dell'Acqua, Tony Charman, Declan GM Murphy, Christine Ecker, Christian F Beckmann, Jan K Buitelaar, EU-AIMS LEAP group
Dec 07, 2020
BACKGROUND: Voxel-based morphometry (VBM) studies in autism spectrum disorder (autism) have yielded diverging results. This might partly be attributed to structural alterations being associating with the combined influence of...
Towards robust and replicable sex differences in the intrinsic brain function of autism
Dorothea L. Floris, José O. A. Filho, Meng-Chuan Lai, Steve Giavasis, Marianne Oldehinkel, Maarten Mennes, Tony Charman, Julian Tillmann, Guillaume Dumas, Christine Ecker, Flavio Dell’Acqua, Tobias Banaschewski, Carolin Moessnang, Simon Baron-Cohen, Sarah Durston, Eva Loth, Declan G. M. Murphy, Jan K. Buitelaar, Christian F. Beckmann, Michael P. Milham, Adriana Di Martino
Mar 02, 2021
Diagnostic and prognostic performance and longitudinal changes in plasma neurofilament light chain concentrations in adults with Down syndrome
Maria Carmona-Iragui, Daniel Alcolea, Isabel Barroeta, Laura Videla, Laia Muñoz, Kathyrn L Van Pelt, Frederick A Schmitt, Donita D Lightner, Lisa M Koehl, Gregory Jicha, Silvia Sacco, Clotilde Mircher, Sarah E Pape, Rosalyn Hithersay, Isabel CH Clare, Anthony J Holland, Georg Nübling, Johannes Levin, Shahid H Zaman, Andre Strydom, Anne-Sophie Rebillat, Elizabeth Head, Rafael Blesa, Alberto Lleó, Juan Fortea
Nov 03, 2021
BACKGROUND: Adults with Down syndrome are at an ultra-high risk of Alzheimer's disease, but diagnosis of Alzheimer's disease in this population is challenging. We aimed to validate the clinical utility of plasma neurofilament...
Investigating the factors underlying adaptive functioning in autism in the EU-AIMS Longitudinal European Autism Project.
Julian Tillmann, Antonia San José Cáceres, Chris H Chatham, Daisy Crawley, Rosemary Holt, Bethany Oakley, Tobias Banaschewski, Simon Baron-Cohen, Sven Bölte, Jan K Buitelaar, Sarah Durston, Lindsay Ham, Eva Loth, Emily Simonoff, Will Spooren, Declan G Murphy, Tony Charman, EU-AIMS LEAP group
May 03, 2019
Individuals with autism spectrum disorder (ASD) exhibit significant impairments in adaptive functioning that impact on their ability to meet the demands of everyday life. A recurrent finding is that there is a pronounced...
adaptive functioning Autism spectrum disorder intellectual functioning psychiatric symptoms symptom severity Activities of Daily Living Adolescent Adult Age Factors Autism spectrum disorder Child Cohort Studies Europe Female Humans Intelligence Longitudinal Studies Male Phenotype Severity of Illness Index Sex Factors Young Adult
Preference for biological motion is reduced in ASD
L Mason, F Shic, T Falck-Ytter, B Chakrabarti, T Charman, E Loth, J Tillmann, T Banaschewski, Simon Baron-Cohen, S Bölte, J Buitelaar, S Durston, B Oranje, AM Persico, C Beckmann, T Bougeron, F Dell'Acqua, C Ecker, C Moessnang, D Murphy, Mark Johnson, EJH Jones, LEAP Team*
Jan 05, 2022
BACKGROUND: The neurocognitive mechanisms underlying autism spectrum disorder (ASD) remain unclear. Progress has been largely hampered by small sample sizes, variable age ranges and resulting inconsistent findings. There is a...
Evaluation of data imputation strategies in complex, deeply-phenotyped data sets
A Llera, M Brammer, B Oakley, J Tillmann, M Zabihi, JS Amelink, T Mei, T Charman, C Ecker, F Dell'Acqua, T Banaschewski, C Moessnang, S Baron-Cohen, R Holt, S Durston, D Murphy, E Loth, JK Buitelaar, DL Floris, CF Beckmann
Sep 15, 2022
An increasing number of large-scale multi-modal research initiatives has been conducted in the typically developing population, e.g. Dev. Cogn. Neur. 32:43-54, 2018; PLoS Med. 12(3):e1001779, 2015; Elam and Van Essen, Enc. Comp....
Preference for biological motion is reduced in ASD
L Mason, F Shic, T Falck-Ytter, B Chakrabarti, T Charman, E Loth, J Tillmann, T Banaschewski, S Baron-Cohen, S Bölte, J Buitelaar, S Durston, B Oranje, AM Persico, C Beckmann, T Bougeron, F Dell'Acqua, C Ecker, C Moessnang, D Murphy, MH Johnson, EJH Jones, LEAP Team*
Jan 28, 2022
BACKGROUND: The neurocognitive mechanisms underlying autism spectrum disorder (ASD) remain unclear. Progress has been largely hampered by small sample sizes, variable age ranges and resulting inconsistent findings. There is a...
|
|< |
< |
1 |