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Improved long-term survival with subdural drains following evacuation of chronic subdural haematoma
Background
Chronic subdural haematoma (CSDH) is a common condition that is effectively managed by burrhole drainage but requires repeat surgery in a significant minority of patients. The Cambridge Chronic Subdural Haematoma...
Efficient compromising
Two agents must select one of three alternatives. Their ordinal rankings are commonly known and diametrically opposed. Efficiency requires choosing the alternative the agents rank second whenever the weighted sum of their von...
Efficient compromising
Two agents must select one of three alternatives. Their ordinal rankings are commonly known and diametrically opposed. Efficiency requires choosing the alternative the agents rank second whenever the weighted sum of their von...
Chronic subdural haematoma
Peter Hutchinson is supported by a Research Professorship from the National Institute for Health Research (NIHR), the NIHR Cambridge Biomedical Research Centre, a European Union Seventh Framework Program grant (CENTER-TBI; grant...
Can compliment and complaint data inform the care of individuals with chronic subdural haematoma (cSDH)?
Katherine Jones, Benjamin Davies, Daniel J Stubbs, Alexander Komashie, Rowan M Burnstein, Peter Hutchinson, Thomas Santarius, Alexis J Joannides
Jul 05, 2022
Core Outcomes and Common Data Elements in Chronic Subdural Hematoma
Aswin Chari, Katie C Hocking, Ellie Edlmann, Carole Turner, Thomas Santarius, Peter J Hutchinson, Angelos G Kolias
Jun 07, 2016
CONNECTIONS, TRACTS, FRACTALS, AND THE REST
Brain mapping and connectomics can probe networks that span the entire brain, producing a diverse range of outputs for probing specific clinically relevant questions. Potential for understanding the impact of focal lesions on...
Methodological shortcomings in the literature evaluating the role and applications of 3D training for surgical trainees.
Milosz Kostusiak, Michael Hart, Damiano Giuseppe Barone, Riikka Hofmann, Ramez Kirollos, Thomas Santarius, Rikin Trivedi
May 29, 2019
AIM: There has been an increased interest in the use of three-dimensional (3D) technology in surgical training. We wish to appraise the methodological rigor applied to evaluating the role and applications of 3D technology in...
Core Outcomes and Common Data Elements in Chronic Subdural Hematoma
Aswin Chari, Katie C Hocking, Ellie Broughton, Carole Turner, Thomas Santarius, Peter J Hutchinson, Angelos G Kolias
Aug 13, 2015
Volumetric growth rates of meningioma and its correlation with histological diagnosis and clinical outcome
Daniel M Fountain, Wai Cheong Soon, Tomasz Matys, Mathew R Guilfoyle, Ramez Kirollos, Thomas Santarius
Feb 05, 2018
INTRODUCTION: Tumour growth has been used to successfully predict progression-free survival in low-grade glioma. This systematic review sought to establish the evidence base regarding the correlation of volumetric growth rates...
A systematic review and meta-analysis of the association between cyproterone acetate and intracranial meningiomas.
Keng Siang Lee, John JY Zhang, Ramez Kirollos, Thomas Santarius, Vincent Diong Weng Nga, Tseng Tsai Yeo
Feb 04, 2022
The influence of exposure to hormonal treatments, particularly cyproterone acetate (CPA), has been posited to contribute to the growth of meningiomas. Given the widespread use of CPA, this systematic review and meta-analysis...
A systematic review and meta-analysis of the association between cyproterone acetate and intracranial meningiomas.
Keng Siang Lee, John JY Zhang, Ramez Kirollos, Thomas Santarius, Vincent Diong Weng Nga, Tseng Tsai Yeo
Mar 08, 2022
The influence of exposure to hormonal treatments, particularly cyproterone acetate (CPA), has been posited to contribute to the growth of meningiomas. Given the widespread use of CPA, this systematic review and meta-analysis...
Can compliment and complaint data inform the care of individuals with chronic subdural haematoma (cSDH)?
Katherine Jones, Benjamin Davies, Daniel J Stubbs, Alexander Komashie, Rowan M Burnstein, Peter Hutchinson, Thomas Santarius, Alexis J Joannides
Sep 23, 2021
Objectives: To explore the frequency and nature of complaints and compliments reported to Patient Advice and Liaison (PALS) in individuals undergoing surgery for a chronic subdural haematoma (cSDH). Design: A retrospective study...
Saliva Samples as A Tool to Study the Effect of Meal Timing on Metabolic And Inflammatory Biomarkers.
Katharina Kessler, Silke Hornemann, Natalia Rudovich, Daniela Weber, Tilman Grune, Achim Kramer, Andreas FH Pfeiffer, Olga Pivovarova-Ramich
Feb 03, 2020
Meal timing affects metabolic regulation in humans. Most studies use blood samples for their investigations. Saliva, although easily available and non-invasive, seems to be rarely used for chrononutritional studies. In this...
Can compliment and complaint data inform the care of individuals with chronic subdural haematoma (cSDH)?
Katherine Jones, Benjamin Davies, Daniel J Stubbs, Alexander Komashie, Rowan M Burnstein, Peter Hutchinson, Thomas Santarius, Alexis J Joannides
Oct 19, 2021
Objectives
To explore the frequency and nature of complaints and compliments reported to Patient Advice and Liaison (PALS) in individuals undergoing surgery for a chronic subdural haematoma (cSDH).Design
A...
Published by: BMJ open quality
BOLD Coupling between Lesioned and Healthy Brain Is Associated with Glioma Patients' Recovery.
Rafael Romero-Garcia, Michael G Hart, Richard A I Bethlehem, Ayan Mandal, Moataz Assem, Benedicto Crespo-Facorro, Juan Manuel Gorriz, G A Amos Burke, Stephen J Price, Thomas Santarius, Yaara Erez, John Suckling
Nov 22, 2021
Predicting functional outcomes after surgery and early adjuvant treatment is difficult due to the complex, extended, interlocking brain networks that underpin cognition. The aim of this study was to test glioma functional...
Published by: Cancers
Molecular determinants underlying functional innovations of TBP and their impact on transcription initiation.
Charles NJ Ravarani, Tilman Flock, Sreenivas Chavali, Madhanagopal Anandapadamanaban, M Madan Babu, Santhanam Balaji
May 20, 2021
Intraoperative mapping of executive function using electrocorticography for patients with low-grade gliomas.
Yaara Erez, Moataz Assem, Pedro Coelho, Rafael Romero-Garcia, Mallory Owen, Alexa McDonald, Emma Woodberry, Robert C Morris, Stephen J Price, John Suckling, John Duncan, Michael G Hart, Thomas Santarius
Nov 23, 2020
BACKGROUND: Intraoperative functional mapping with direct electrical stimulation during awake surgery for patients with diffuse low-grade glioma has been used in recent years to optimize the balance between surgical resection...
Awake neurosurgery Brain tumor Electrocorticography (ECOG) Executive Function Functional mapping intraoperative Low-grade glioma Patients Adult Brain Mapping Brain Neoplasms Cognition Electric Stimulation Electrocorticography Executive Function Female Gamma Rhythm glioma Humans Intraoperative Care Magnetic Resonance Imaging Male Middle Aged Quality of life
Practical Application of Networks in Neurosurgery
Rafael Romero-Garcia, Yaara Erez, Geoffrey Oliver, Mallory Owen, Sakinah Merali, Anujan Poologaindran, Robert C Morris, Stephen J Price, Thomas Santarius, John Suckling, Michael G Hart
Feb 26, 2020
BACKGROUND: A plethora of cutting edge neuroimaging analyses have been developed and published yet they have not hitherto been realized as improvements in neurosurgical outcomes. In this paper we propose a novel interface...
Memory recovery in relation to default mode network impairment and neurite density during brain tumor treatment.
Skull base repair following endonasal pituitary and skull base tumour resection
Danyal Z Khan, Ahmad MS Ali, Chan Hee Koh, Neil L Dorward, Joan Grieve, Hugo Layard Horsfall, William Muirhead, Thomas Santarius, Wouter R Van Furth, Amir H Zamanipoor Najafabadi, Hani J Marcus
Sep 03, 2021
PURPOSE: Postoperative cerebrospinal fluid rhinorrhoea (CSFR) remains a frequent complication of endonasal approaches to pituitary and skull base tumours. Watertight skull base reconstruction is important in preventing CSFR. We...
CSF cerebrospinal fluid Cerebrospinal Fluid Leak Cerebrospinal fluid rhinorrhoea Endoscopic endonasal Endoscopic transsphenoidal surgery Skull base surgery Cerebrospinal Fluid Leak Cerebrospinal Fluid Rhinorrhea endoscopy Humans Postoperative Complications Retrospective Studies Skull Base Skull Base Neoplasms
Time to surgery following chronic subdural hematoma
Sara Venturini, Daniel M Fountain, Laurence J Glancz, Laurent J Livermore, Ian C Coulter, Simon Bond, Basil Matta, Thomas Santarius, Peter J Hutchinson, Paul M Brennan, Angelos G Kolias, British Neurosurgical Trainee Research Collaborative (BNTRC)
Dec 26, 2019
BACKGROUND: Chronic subdural hematoma (CSDH) is a common neurological condition; surgical evacuation is the mainstay of treatment for symptomatic patients. No clear evidence exists regarding the impact of timing of surgery on...
Published by: BMJ Surg Interv Health Technol
Base resolution maps reveal the importance of 5-hydroxymethylcytosine in a human glioblastoma
EA Raiber, D Beraldi, S Martinez Cuesta, GR McInroy, Z Kingsbury, J Becq, T James, M Lopes, K Allinson, S Field, S Humphray, T Santarius, C Watts, D Bentley, S Balasubramanian
Feb 23, 2017
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