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Results: 1489
The HIF-1/glial TIM-3 axis controls inflammation-associated brain damage under hypoxia.
Han Seok Koh, Chi Young Chang, Sae-Bom Jeon, Hee Jung Yoon, Ye-Hyeon Ahn, Hyung-Seok Kim, In-Hoo Kim, Sung Ho Jeon, Randall S Johnson, Eun Jung Park
Mar 13, 2020
Inflammation is closely related to the extent of damage following cerebral ischaemia, and the targeting of this inflammation has emerged as a promising therapeutic strategy. Here, we present that hypoxia-induced glial T-cell...
Animals Astrocytes Brain Carotid Artery Common Cell Movement Cells Cultured Hepatitis A Virus Cellular Receptor 2 Hypoxia-Inducible Factor 1 alpha Subunit Hypoxia-Ischemia Brain Immunohistochemistry In Vitro Techniques Inflammation Ligation Magnetic Resonance Imaging Mesencephalon Mice Microglia Neuroglia Neutrophils RNA Messenger Receptors Virus Reverse Transcriptase Polymerase Chain Reaction
IL-15, TIM-3 and NK cells subsets predict responsiveness to anti-CTLA-4 treatment in melanoma patients
R Tallerico, CM Cristiani, E Staaf, C Garofalo, R Sottile, M Capone, Y Pico de Coaña, G Madonna, E Palella, M Wolodarski, V Carannante, D Mallardo, E Simeone, AM Grimaldi, S Johansson, P Frumento, E Gulletta, A Anichini, F Colucci, G Ciliberto, R Kiessling, K Kärre, PA Ascierto, E Carbone
Jul 20, 2017
Despite the success of immune checkpoint blockade in melanoma, the majority of patients do not respond. We hypothesized that the T and NK cell subset frequencies and expression levels of their receptors may predict responses and...
Governor Appoints Don Long and Tim Hopkins to Winthrop Board of Trustees
Winthrop University
Jan 01, 0001
Don Long of Lake Wylie will fill the appointee slot held by Tommy Pope, who was elected to the S.C. House of Representatives in November and had to resign. Tim Hopkins, an executive director of elementary education in the...
Published by: Winthrop University
Psychology Professor Tim Daugherty Elected as New Chair of Faculty Conference
Winthrop University
Jan 01, 0001
Tim Daugherty, an associate professor of psychology in the College of Arts and Sciences, will replace Marilyn Smith, a professor of business administration who has served since 2002. He will become the faculty chair in July...
Published by: Winthrop University
The population growth consequences of variation in individual heterozygosity.
Martina MI Di Fonzo, Fanie Pelletier, TH Clutton-Brock, Josephine M Pemberton, Tim Coulson
Jan 23, 2018
Heterozygosity has been associated with components of fitness in numerous studies across a wide range of taxa. Because heterozygosity is associated with individual performance it is also expected to be associated with population...
Translating student evaluation of teaching
Student evaluation of teaching (SET) has not yet been studied historically and comparatively. Based on our interviews with professors and administrators at 18 universities in three countries, we discuss how SET diffused in all...
Translating student evaluation of teaching
Student evaluation of teaching (SET) has not yet been studied historically and comparatively. Based on our interviews with professors and administrators at 18 universities in three countries, we discuss how SET diffused in all...
Investigating the Impact of Crohn's Disease on the Bioaccessibility of a Lipid-Based Formulation with an in Vitro Dynamic Gastrointestinal Model
Angela Effinger, Mark McAllister, Irena Tomaszewska, Caitriona M. O'Driscoll, Mark Taylor, Steve Gomersall, James Heaton, Kieran L. Smith, Inese Sarcevica, Sam L. Young, Nikoletta Fotaki
Apr 05, 2021
The aim of the study was to investigate the impact of Crohn's disease (CD) on the performance of a lipid-based formulation of ciprofloxacin in a complex gastrointestinal simulator (TIM-1, TNO) and to compare the luminal...
bile salts Crohn's Disease Fatty Acids lipid-based formulation lipidomics luminal environment TIM-1 TNO /dk/atira/pure/subjectarea/asjc/1300/1313 name=Molecular Medicine /dk/atira/pure/subjectarea/asjc/3000/3003 name=Pharmaceutical Science /dk/atira/pure/subjectarea/asjc/3000/3002 name=Drug Discovery /dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_being name=SDG 3 - Good Health and Well-being
Investigating the Impact of Crohn's Disease on the Bioaccessibility of a Lipid-Based Formulation with an in Vitro Dynamic Gastrointestinal Model
Angela Effinger, Mark McAllister, Irena Tomaszewska, Caitriona M. O'Driscoll, Mark Taylor, Steve Gomersall, James Heaton, Kieran L. Smith, Inese Sarcevica, Sam L. Young, Nikoletta Fotaki
Apr 05, 2021
The aim of the study was to investigate the impact of Crohn's disease (CD) on the performance of a lipid-based formulation of ciprofloxacin in a complex gastrointestinal simulator (TIM-1, TNO) and to compare the luminal...
bile salts Crohn's Disease Fatty Acids lipid-based formulation lipidomics luminal environment TIM-1 TNO /dk/atira/pure/subjectarea/asjc/1300/1313 name=Molecular Medicine /dk/atira/pure/subjectarea/asjc/3000/3003 name=Pharmaceutical Science /dk/atira/pure/subjectarea/asjc/3000/3002 name=Drug Discovery /dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_being name=SDG 3 - Good Health and Well-being
Factors Influencing Intention to Use Online Consumer Reviews
Online consumer reviews have been shown to play an important role that can influence consumers' attitudes, behaviors, and purchasing decisions. This study seeks to understand factors that affect user intention to use online...
Published by: IGI Global Scientific Publishing
Greenville Event Planned for Alumni Association's New President
Winthrop University
Jan 01, 0001
Magee, a Greenville, S.C., resident, replaces Tim Hopkins who was recently appointed to the Winthrop Board of Trustees as a designee for S.C. Governor Nikki Haley. The Alumni Association will host a reception welcoming Magee in...
Published by: Winthrop University
AUTHOR BOOK TALK
The Rockefeller University
Jan 01, 0001
Tim M. Berra: Wallace's Acceptance of Darwin's Priority in His Own Words
Published by: The Rockefeller University
Meeting the support needs of patients with complex regional pain syndrome through innovative use of wiki technology
Background: Using online discussion forums can have a positive impact on psychological well-being through development of shared group identity and validation of thoughts, feelings and experiences. This may be particularly...
Meeting the support needs of patients with complex regional pain syndrome through innovative use of wiki technology
Background: Using online discussion forums can have a positive impact on psychological well-being through development of shared group identity and validation of thoughts, feelings and experiences. This may be particularly...
Two New Board Members Added to Winthrop Board of Trustees
Winthrop University
Jan 01, 0001
Tommy Pope and Tim Sease will join the Winthrop Board of Trustees in July. Pope has law enforcement and courtroom experience, while Sease oversees an investment company.
Published by: Winthrop University
American Party Event on Sept. 30 Features Co-Founder and U.S. Senate Candidate
Winthrop University
Jan 01, 0001
Jill Bossi of Tega Cay, South Carolina, is running for the U.S. Senate seat held by Tim Scott. Jim Rex, one of the American Party founders and a former S.C. education superintendent, will talk about creation of the party and...
Published by: Winthrop University
Getting out and about in older adults
Mark G Davis, Kenneth R Fox, Melvyn Hillsdon, Jo C Coulson, Debbie J Sharp, Afroditi Stathi, Janice L Thompson
Oct 21, 2011
Background: A key public health objective is increasing health-enhancing physical activity (PA) for older adults (OAs). Daily trip frequency is independently associated with objectively assessed PA volumes (OAs). Little is...
Investigating Change Management Based on Participation and Acceptance of IT in the Public Sector
The digitalization of public administrations faces big challenges regarding employees' acceptance of IT. Change management approaches based on participation should help achieving acceptance and success of IT projects in the...
Published by: IGI Global Scientific Publishing
A Comparative Study of Trust in Mobile Banking
With the rapid growth of mobile phone usage, mobile services have influenced many industries including banking. Mobile banking has become a popular service as it offers a convenient channel for customers to perform banking...
Published by: IGI Global Scientific Publishing
Objective indicators of physical activity and sedentary time and associations with subjective well-being in adults aged 70 and over
Janet Withall, Afroditi Stathi, Mark Davis, Jo Coulson, Janice L Thompson, Kenneth R Fox
Jan 02, 2014
This study explored the associations of the volume and intensity of physical activity and the volume of sedentary time with subjective well-being in a diverse group of 228 older adults in the UK (111 female, mean age 78.2 years...
A systematic review on the efficacy of tranexamic acid in head and neck surgery
Warda Jamshaid, Maryam Jamshaid, Chris Coulson, Neil Sharma, Jameel Muzaffar, Hannah Nieto
Apr 12, 2023
Background: Intraoperative and postoperative blood loss is a major risk in head and neck (H&N) surgery. Recently the use of tranexamic acid (TXA) has been investigated by multiple studies for reducing intraoperative and...
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