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Optic Chiasm Morphometric Changes in Multiple Sclerosis
Sophisticated volume measurements of brain structures on magnetic resonance imaging (MRI) may improve specificity in determining long-term progression of multiple sclerosis (MS), but these techniques are laborious. The optic...
A critical appraisal of Monro's erroneous description of the cerebral interventricular foramina
Anatomic connections between the cerebral lateral and third ventricles have been mischaracterized since Monro's original erroneous description of his eponymous foramina (FoMs) as being only one T-shaped passage. Accurate...
A Neural Network Approach to Identify the Peritumoral Invasive Areas in Glioblastoma Patients by Using MR Radiomics
Jiun-Lin Yan, Chao Li, Anouk van der Hoorn, Natalie R. Boonzaier, Tomasz Matys, Stephen J. Price
Jun 17, 2021
Abstract: The challenge in the treatment of glioblastoma is the failure to identify the cancer invasive area outside the contrast-enhancing tumour which leads to the high local progression rate. Our study aims to identify its...
A rare case of bone marrow infiltration by medulloblastoma in a child.
Anna Santarsieri, Emmy Dickens, C Elizabeth Hook, Kieren Allinson, Tomasz Matys, Matthew J Murray
May 03, 2019
A seven-year-old boy was previously treated for the primarya posterior fossa tumour, medulloblastoma, with extensive central nervous system metastases including leptomeningeal and intrathecal spinal disease; methylation...
Volumetric growth rates of meningioma and its correlation with histological diagnosis and clinical outcome
Daniel M Fountain, Wai Cheong Soon, Tomasz Matys, Mathew R Guilfoyle, Ramez Kirollos, Thomas Santarius
Feb 05, 2018
INTRODUCTION: Tumour growth has been used to successfully predict progression-free survival in low-grade glioma. This systematic review sought to establish the evidence base regarding the correlation of volumetric growth rates...
Routine preoperative brain CT in resectable non-small cell lung cancer - Ten years experience from a tertiary UK thoracic center.
Tomasz Matys, Rosalyn Drury, Sarojini David, Doris M Rassl, Wendi Qian, Robert C Rintoul, Nicholas J Screaton
Oct 10, 2018
brain metastasis Computed tomography Non-small cell lung carcinoma staging Adult Aged Aged 80 and over Brain Brain Neoplasms Carcinoma Non-Small-Cell Lung Diagnostic Tests Routine Female Follow-Up Studies Humans Lung Neoplasms Magnetic Resonance Imaging Male Middle Aged Neoplasm Metastasis Neoplasm Staging Positron-Emission Tomography Preoperative Care prevalence Tertiary Care Centers Tomography X-Ray Computed United Kingdom
A Neural Network Approach to Identify the Peritumoral Invasive Areas in Glioblastoma Patients by Using MR Radiomics
Jiun-Lin Yan, Chao Li, Anouk van der Hoorn, Natalie R. Boonzaier, Tomasz Matys, Stephen J. Price
Jun 16, 2020
Abstract: The challenge in the treatment of glioblastoma is the failure to identify the cancer invasive area outside the contrast-enhancing tumour which leads to the high local progression rate. Our study aims to identify its...
A Neural Network Approach to Identify the Peritumoral Invasive Areas in Glioblastoma Patients by Using MR Radiomics
Jiun-Lin Yan, Chao Li, Anouk van der Hoorn, Natalie R. Boonzaier, Tomasz Matys, Stephen J. Price
Aug 11, 2020
Abstract: The challenge in the treatment of glioblastoma is the failure to identify the cancer invasive area outside the contrast-enhancing tumour which leads to the high local progression rate. Our study aims to identify its...
Anouk van der Hoorn, Jiun-Lin Yan, Timothy J Larkin, Natalie R Boonzaier, Tomasz Matys, Stephen J Price
May 12, 2016
Apparent diffusion coefficient Brain tumor Glioblastoma Magnetic Resonance Imaging treatment response Aged Brain Neoplasms Cohort Studies Diffusion Magnetic Resonance Imaging Female Glioblastoma Humans Image Processing Computer-Assisted Male Middle Aged Neoplasm Recurrence Local Regression Analysis Survival Analysis Treatment Outcome Tumor Burden
Validation of a semi-automatic co-registration of MRI scans in patients with brain tumors during treatment follow-up.
Anouk van der Hoorn, Jiun-Lin Yan, Timothy J Larkin, Natalie R Boonzaier, Tomasz Matys, Stephen J Price
Apr 01, 2016
MRI brain tumors high-grade gliomas linear co-registration non-linear co-registration structural similarity treatment response validation Adult Aged Algorithms Brain Neoplasms Female Follow-Up Studies Glioblastoma Humans Image Enhancement Image Interpretation Computer-Assisted Longitudinal Studies Magnetic Resonance Imaging Male Middle Aged pattern recognition Automated Sensitivity and Specificity Subtraction Technique Treatment Outcome
A Neural Network Approach to Identify the Peritumoral Invasive Areas in Glioblastoma Patients by Using MR Radiomics.
Jiun-Lin Yan, Chao Li, Anouk van der Hoorn, Natalie R Boonzaier, Tomasz Matys, Stephen J Price
Jul 02, 2020
The challenge in the treatment of glioblastoma is the failure to identify the cancer invasive area outside the contrast-enhancing tumour which leads to the high local progression rate. Our study aims to identify its progression...
Adult Aged Aminolevulinic Acid Brain Neoplasms Cohort Studies Contrast Media Diffusion Magnetic Resonance Imaging Disease Progression Female Glioblastoma Humans Image Processing Computer-Assisted Magnetic Resonance Imaging Magnetic Resonance Spectroscopy Male Middle Aged Neural Networks Computer Optical Imaging Retrospective Studies
Hyperpolarized 13C MRI
James T Grist, Jack J Miller, Fulvio Zaccagna, Mary A McLean, Frank Riemer, Tomasz Matys, Damian J Tyler, Christoffer Laustsen, Alasdair J Coles, Ferdia A Gallagher
Mar 17, 2020
Cerebral metabolism is tightly regulated and fundamental for healthy neurological function. There is increasing evidence that alterations in this metabolism may be a precursor and early biomarker of later stage disease...
Investigating the relationship between diffusion kurtosis tensor imaging (DKTI) and histology within the normal human brain.
Ahmed Maiter, Frank Riemer, Kieren Allinson, Fulvio Zaccagna, Mireia Crispin-Ortuzar, Marcel Gehrung, Mary A McLean, Andrew N Priest, James Grist, Tomasz Matys, Martin J Graves, Ferdia A Gallagher
Mar 29, 2021
Measurements of water diffusion with MRI have been used as a biomarker of tissue microstructure and heterogeneity. In this study, diffusion kurtosis tensor imaging (DKTI) of the brain was undertaken in 10 healthy volunteers at a...
Ossification of the pterygoalar and pterygospinous ligaments
Tomasz Matys, Tariq Ali, Fulvio Zaccagna, Damiano G Barone, Ramez W Kirollos, Tarik F Massoud
May 24, 2019
OBJECTIVE: Ossification of pterygoalar and pterygospinous ligaments traversing the superior aspect of the infratemporal fossa results in formation of osseous bars that can obstruct percutaneous needle access to the trigeminal...
Low perfusion compartments in glioblastoma quantified by advanced magnetic resonance imaging and correlated with patient survival.
Chao Li, Jiun-Lin Yan, Turid Torheim, Mary A McLean, Natalie R Boonzaier, Jingjing Zou, Yuan Huang, Jianmin Yuan, Bart RJ van Dijken, Tomasz Matys, Florian Markowetz, Stephen J Price
Feb 25, 2019
BACKGROUND AND PURPOSE: Glioblastoma exhibits profound intratumoral heterogeneity in perfusion. Particularly, low perfusion may induce treatment resistance. Thus, imaging approaches that define low perfusion compartments are...
diffusion imaging Glioblastoma Heterogeneity Perfusion Imaging radioresistance Tumor habitat imaging Adult Aged Chemoradiotherapy Cohort Studies Diffusion Magnetic Resonance Imaging Female Glioblastoma Humans Kaplan-Meier Estimate Magnetic Resonance Imaging Male Middle Aged Neoplasm Invasiveness Supratentorial Neoplasms Survival Rate Temozolomide Young Adult
Multi-parametric and multi-regional histogram analysis of MRI
Chao Li, Shuo Wang, Angela Serra, Turid Torheim, Jiun-Lin Yan, Natalie R Boonzaier, Yuan Huang, Tomasz Matys, Mary A McLean, Florian Markowetz, Stephen J Price
Feb 25, 2019
OBJECTIVES: Integrating multiple imaging modalities is crucial for MRI data interpretation. The purpose of this study is to determine whether a previously proposed multi-view approach can effectively integrate the histogram...
Glioblastoma Machine Learning Magnetic Resonance Imaging Prognosis Survival Analysis Brain Brain Neoplasms Cluster Analysis Contrast Media Female Glioblastoma Humans Image Enhancement Kaplan-Meier Estimate Magnetic Resonance Imaging Magnetic Resonance Spectroscopy Male Middle Aged Phenotype Proportional Hazards Models Reproducibility of Results Retrospective Studies
Investigating the relationship between diffusion kurtosis tensor imaging (DKTI) and histology within the normal human brain
Characterizing tumor invasiveness of glioblastoma using multiparametric magnetic resonance imaging.
Chao Li, Shuo Wang, Jiun-Lin Yan, Turid Torheim, Natalie R Boonzaier, Rohitashwa Sinha, Tomasz Matys, Florian Markowetz, Stephen J Price
Mar 21, 2019
Local alkylating chemotherapy applied immediately after 5-ALA guided resection of glioblastoma does not provide additional benefit.
William Sage, Mathew Guilfoyle, Catriona Luney, Adam Young, Rohitashwa Sinha, Donatella Sgubin, Joseph H McAbee, Ruichong Ma, Sarah Jefferies, Rajesh Jena, Fiona Harris, Kieren Allinson, Tomasz Matys, Wendi Qian, Thomas Santarius, Stephen Price, Colin Watts
May 25, 2018
Grade IV glioma is the most common and aggressive primary brain tumour. Gross total resection with 5-aminolevulinic acid (5-ALA) guided surgery combined with local chemotherapy (carmustine wafers) is an attractive treatment...
An Evaluation of the Tolerability and Feasibility of Combining 5-Amino-Levulinic Acid (5-ALA) with BCNU Wafers in the Surgical Management of Primary Glioblastoma
Colin Watts, Keyoumars Ashkan, Michael D. Jenkinson, Stephen J. Price, Thomas Santarius, Tomasz Matys, Ting Ting Zhang, Alina Finch, Peter Collins, Kieren Allinson, Sarah J. Jefferies, Daniel J. Scoffings, Athanasios Zisakis, Mark Phillips, Katharina Wanek, Paul Smith, Laura Clifton-Hadley, Nicholas Counsell
Jul 02, 2021
Background Glioblastoma (GBM) is the commonest primary malignant brain tumour in adults and effective treatment options are limited. Combining local chemotherapy with enhanced surgical resection using 5-aminolevulinic acid...
An Evaluation of the Tolerability and Feasibility of Combining 5-Amino-Levulinic Acid (5-ALA) with BCNU Wafers in the Surgical Management of Primary Glioblastoma.
Colin Watts, Keyoumars Ashkan, Michael D Jenkinson, Stephen J Price, Thomas Santarius, Tomasz Matys, Ting Ting Zhang, Alina Finch, Peter Collins, Kieren Allinson, Sarah J Jefferies, Daniel J Scoffings, Athanasios Zisakis, Mark Phillips, Katharina Wanek, Paul Smith, Laura Clifton-Hadley, Nicholas Counsell
Sep 05, 2021
Background Glioblastoma (GBM) is the commonest primary malignant brain tumour in adults and effective treatment options are limited. Combining local chemotherapy with enhanced surgical resection using 5-aminolevulinic acid...
Modern imaging of pituitary adenomas.
Waiel A Bashari, Russell Senanayake, Antía Fernández-Pombo, Daniel Gillett, Olympia Koulouri, Andrew S Powlson, Tomasz Matys, Daniel Scoffings, Heok Cheow, Iosif Mendichovszky, Mark Gurnell
Aug 21, 2019
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