Search
Results: 1
Discrimination of Dormant and Active Hematopoietic Stem Cells by G0 Marker Reveals Dormancy Regulation by Cytoplasmic Calcium.
Tsuyoshi Fukushima, Yosuke Tanaka, Fiona K Hamey, Chih-Hsiang Chang, Toshihiko Oki, Shuhei Asada, Yasutaka Hayashi, Takeshi Fujino, Taishi Yonezawa, Reina Takeda, Kimihito Cojin Kawabata, Tomofusa Fukuyama, Terumasa Umemoto, Keiyo Takubo, Hitoshi Takizawa, Susumu Goyama, Yasushi Ishihama, Hiroaki Honda, Berthold Göttgens, Toshio Kitamura
Dec 16, 2019
Quiescent hematopoietic stem cells (HSCs) are typically dormant, and only a few quiescent HSCs are active. The relationship between "dormant" and "active" HSCs remains unresolved. Here we generate a G0 marker (G0M) mouse line...
CDK G(0) phase HSC Calcium Cell Cycle dormancy Hematopoietic stem cell p27 Animals Biomarkers Calcium Cell Proliferation Cell Self Renewal Cytoplasm Female Gene Expression Profiling Gene Expression Regulation Gene Regulatory Networks Hematopoietic Stem Cells Male Mice Mice Inbred C57BL Resting Phase Cell Cycle Single-Cell Analysis