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Results: 179
On randomized sketching algorithms and the Tracy-Widom law.
UNLABELLED: There is an increasing body of work exploring the integration of random projection into algorithms for numerical linear algebra. The primary motivation is to reduce the overall computational cost of processing large...
On randomized sketching algorithms and the Tracy-Widom law.
UNLABELLED: There is an increasing body of work exploring the integration of random projection into algorithms for numerical linear algebra. The primary motivation is to reduce the overall computational cost of processing large...
A Kallikrein 15 (KLK15) single nucleotide polymorphism located close to a novel exon shows evidence of association with poor ovarian cancer survival.
Jyotsna Batra, Christina M Nagle, Tracy O'Mara, Melanie Higgins, Ying Dong, Olivia L Tan, Felicity Lose, Lene Marie Skeie, Srilakshmi Srinivasan, Kelly L Bolton, Honglin Song, Susan J Ramus, Simon A Gayther, Paul DP Pharoah, Mary-Anne Kedda, Amanda B Spurdle, Judith A Clements
Jun 16, 2011
A Common Variant at the 14q32 Endometrial Cancer Risk Locus Activates AKT1 through YY1 Binding.
Jodie N Painter, Susanne Kaufmann, Tracy A O'Mara, Kristine M Hillman, Haran Sivakumaran, Hatef Darabi, Timothy Ht Cheng, John Pearson, Stephen Kazakoff, Nicola Waddell, Erling A Hoivik, Ellen L Goode, Rodney J Scott, Ian Tomlinson, Alison M Dunning, Douglas F Easton, Juliet D French, Helga B Salvesen, Pamela M Pollock, Deborah J Thompson, Amanda B Spurdle, Stacey L Edwards
May 17, 2016
Chromosomes Human Pair 14 Endometrial Neoplasms Female Genetic Loci Genetic Predisposition to Disease Genome-Wide Association Study Genotype Humans Phosphatidylinositol 3-Kinases Polymorphism Single Nucleotide Protein Binding Proto-Oncogene Proteins c-akt Risk Factors Signal Transduction Uterine Neoplasms YY1 Transcription Factor
Non-coding RNAs underlie genetic predisposition to breast cancer.
Mahdi Moradi Marjaneh, Jonathan Beesley, Tracy A O'Mara, Pamela Mukhopadhyay, Lambros T Koufariotis, Stephen Kazakoff, Nehal Hussein, Laura Fachal, Nenad Bartonicek, Kristine M Hillman, Susanne Kaufmann, Haran Sivakumaran, Chanel E Smart, Amy E McCart Reed, Kaltin Ferguson, Jodi M Saunus, Sunil R Lakhani, Daniel R Barnes, Antonis C Antoniou, Marcel E Dinger, Nicola Waddell, Douglas F Easton, Alison M Dunning, Georgia Chenevix-Trench, Stacey L Edwards, Juliet D French
Feb 08, 2020
BACKGROUND:Genetic variants identified through genome-wide association studies (GWAS) are predominantly non-coding and typically attributed to altered regulatory elements such as enhancers and promoters. However, the...
Published by: Genome biology
McNair Scholar Studies Student Truck Drivers' Health to Improve Performance
Winthrop University
Jan 01, 0001
Shalace Rose, a McNair Scholar and senior who won an award for her truck driver research, has interviewed nearly 30 student drivers at York Technical College in order to draw some general characteristics about truckers. Truck...
Published by: Winthrop University
Pauling and Frech reply
We thank Dr. Hughes for his interest1 in our article2 reporting factors influencing Raynaud phenomenon (RP) symptom reporting in patients with systemic sclerosis (SSc). We presented data demonstrating differences in Raynaud...
Evidence of a Causal Association Between Insulinemia and Endometrial Cancer
Kevin T Nead, Stephen J Sharp, Deborah J Thompson, Jodie N Painter, David B Savage, Robert K Semple, Adam Barker, Australian National Endometrial Cancer Study Group (ANECS), John RB Perry, John Attia, Alison M Dunning, Douglas F Easton, Elizabeth Holliday, Luca A Lotta, Tracy O'Mara, Mark McEvoy, Paul DP Pharoah, Rodney J Scott, Amanda B Spurdle, Claudia Langenberg, Nicholas J Wareham, Robert A Scott
Jun 19, 2015
Using human genetics to understand the disease impacts of testosterone in men and women.
Katherine S Ruth, Felix R Day, Jessica Tyrrell, Deborah J Thompson, Andrew R Wood, Anubha Mahajan, Robin N Beaumont, Laura Wittemans, Susan Martin, Alexander S Busch, A Mesut Erzurumluoglu, Benjamin Hollis, Tracy A O'Mara, Endometrial Cancer Association Consortium, Mark I McCarthy, Claudia Langenberg, Douglas F Easton, Nicholas J Wareham, Stephen Burgess, Anna Murray, Ken K Ong, Timothy M Frayling, John RB Perry
Dec 12, 2019
Biological Specimen Banks Biomarkers Body composition Breast Neoplasms Cluster Analysis Diabetes mellitus Type 2 Endometrial Neoplasms Estradiol Female Genome-Wide Association Study Genotype Haplotypes Humans Male Mendelian Randomization Analysis Odds Ratio Phenotype POLYCYSTIC OVARY SYNDROME Polymorphism Single Nucleotide Prostatic Neoplasms Sex Factors Software Testosterone United Kingdom
"Are We Playing a Game Today?" Classroom Engagement and Assessment Through Gamification
Today's classroom demands a different style of engagement and assessment, primarily due to the changing nature of today's learners. In fact, according to Liz Dwyer in "How Gaming is Changing the Classroom," by the time students...
engagement assessment gamification Gaming Education English Language and Literature Higher Education and Teaching Scholarship of Teaching and Learning
Published by: Winthrop University
Youth sport
Participation in youth sport has been promoted as part of a healthy lifestyle, with benefits for physical fitness, social development, and mental wellbeing. Yet, sport carries an inherent risk of injury, which for young athletes...
Youth sport
Participation in youth sport has been promoted as part of a healthy lifestyle, with benefits for physical fitness, social development, and mental wellbeing. Yet, sport carries an inherent risk of injury, which for young athletes...
Infants' lexical comprehension and lexical anticipation abilities are closely linked in early language development.
Theories across cognitive domains propose that anticipating upcoming sensory input supports information processing. In line with this view, prior findings indicate that adults and children anticipate upcoming words during...
Pauling and Frech reply
We thank Dr. Hughes for his interest1 in our article2 reporting factors influencing Raynaud phenomenon (RP) symptom reporting in patients with systemic sclerosis (SSc). We presented data demonstrating differences in Raynaud...
Pinpointing needles in giant haystacks
Ian Shemilt, Antonia Simon, Gareth J Hollands, Theresa M Marteau, David Ogilvie, Alison O'Mara-Eves, Michael P Kelly, James Thomas
May 09, 2018
In scoping reviews, boundaries of relevant evidence may be initially fuzzy, with refined conceptual understanding of interventions and their proposed mechanisms of action an intended output of the scoping process rather than its...
Post graduate clinical placements
Jenny Yiend, Derek K Tracy, Brian Sreenan, Valentina Cardi, Tina Foulkes, Katerina Koutsantoni, Eugenia Kravariti, Kate Tchanturia, Lucy Willmott, Sukhi Shergill, Gabriel Reedy
Sep 29, 2016
BACKGROUND: Systematic evaluations of clinical placements are rare, especially when offered alongside academic postgraduate courses. An evidence-based approach is important to allow pedagogically-driven provision, rather than...
Non-coding RNAs underlie genetic predisposition to breast cancer.
Mahdi Moradi Marjaneh, Jonathan Beesley, Tracy A O'Mara, Pamela Mukhopadhyay, Lambros T Koufariotis, Stephen Kazakoff, Nehal Hussein, Laura Fachal, Nenad Bartonicek, Kristine M Hillman, Susanne Kaufmann, Haran Sivakumaran, Chanel E Smart, Amy E McCart Reed, Kaltin Ferguson, Jodi M Saunus, Sunil R Lakhani, Daniel R Barnes, Antonis C Antoniou, Marcel E Dinger, Nicola Waddell, Douglas F Easton, Alison M Dunning, Georgia Chenevix-Trench, Stacey L Edwards, Juliet D French
Dec 16, 2019
BACKGROUND: Genetic variants identified through genome-wide association studies (GWAS) are predominantly non-coding and typically attributed to altered regulatory elements such as enhancers and promoters. However, the...
Factors influencing Raynaud condition score diary outcomes in systemic sclerosis
Objective. Raynaud phenomenon (RP) in systemic sclerosis (SSc) could be influenced by clinical phenotype, environmental factors (e.g., season), and personal factors (e.g., coping strategies and ill-health perceptions). We...
Clinical Trials outcome measures patient-reported outcomes Raynaud phenomenon systemic sclerosis Validation Studies /dk/atira/pure/subjectarea/asjc/2700/2745 name=Rheumatology /dk/atira/pure/subjectarea/asjc/2700/2723 name=Immunology and Allergy /dk/atira/pure/subjectarea/asjc/2400/2403 name=Immunology
Neurocognitive trajectory and proteomic signature of inherited risk for Alzheimer's disease.
Manish D Paranjpe, Mark Chaffin, Sohail Zahid, Scott Ritchie, Jerome I Rotter, Stephen S Rich, Robert Gerszten, Xiuqing Guo, Susan Heckbert, Russ Tracy, John Danesh, Eric S Lander, Michael Inouye, Sekar Kathiresan, Adam S Butterworth, Amit V Khera
Oct 01, 2022
A comprehensive re-assessment of the association between vitamin D and cancer susceptibility using Mendelian randomization.
Jue-Sheng Ong, Suzanne C Dixon-Suen, Xikun Han, Jiyuan An, Esophageal Cancer Consortium, 23 and Me Research Team, Upekha Liyanage, Jean-Cluade Dusingize, Johannes Schumacher, Ines Gockel, Anne Böhmer, Janusz Jankowski, Claire Palles, Tracy O'Mara, Amanda Spurdle, Matthew H Law, Mark M Iles, Paul Pharoah, Andrew Berchuck, Wei Zheng, Aaron P Thrift, Catherine Olsen, Rachel E Neale, Puya Gharahkhani, Penelope M Webb, Stuart MacGregor
Feb 01, 2021
Previous Mendelian randomization (MR) studies on 25-hydroxyvitamin D (25(OH)D) and cancer have typically adopted a handful of variants and found no relationship between 25(OH)D and cancer; however, issues of horizontal...
Neurocognitive trajectory and proteomic signature of inherited risk for Alzheimer's disease.
Manish D Paranjpe, Mark Chaffin, Sohail Zahid, Scott Ritchie, Jerome I Rotter, Stephen S Rich, Robert Gerszten, Xiuqing Guo, Susan Heckbert, Russ Tracy, John Danesh, Eric S Lander, Michael Inouye, Sekar Kathiresan, Adam S Butterworth, Amit V Khera
Sep 02, 2022
Evolving Symptom Characteristics of Raynaud's Phenomenon in Systemic Sclerosis and Their Association With Physician and Patient-Reported Assessments of Disease Severity
Objective: Assessment of Raynaud's phenomenon (RP) in systemic sclerosis (SSc) is reliant on self-report. The Raynaud's Condition Score (RCS) diary assumes discrete episodic RP attacks, although not all SSc patients identify...
Evolving Symptom Characteristics of Raynaud's Phenomenon in Systemic Sclerosis and Their Association With Physician and Patient-Reported Assessments of Disease Severity
Objective: Assessment of Raynaud's phenomenon (RP) in systemic sclerosis (SSc) is reliant on self-report. The Raynaud's Condition Score (RCS) diary assumes discrete episodic RP attacks, although not all SSc patients identify...
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