Pyramidal cell apical dendrites in region CA3 of the hippocampus of male rats collapse in size and complexity following chronic stress. These dendrites return to control sizes with a recovery period. This suggests that dendritic...
In this paper we prove a group theoretic analogue of the well known local nilpotence theorem for sandwich Lie algebras due to Kostrikin and Zel’manov [Trudy Mat. Inst. Steklov. 183 (1990), pp. 106–111, 225]. We introduce the...
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In this paper we prove a group theoretic analogue of the well known local nilpotence theorem for sandwich Lie algebras due to Kostrikin and Zel’manov [Trudy Mat. Inst. Steklov. 183 (1990), pp. 106–111, 225]. We introduce the...
Epigenetic mechanisms, including DNA methylation and histone modifications, might be involved in the regulation of blood lipid concentration variability and may thereby affect cardiovascular health. We aimed to systematically...
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Abstract: We conducted genome-wide association studies (GWAS) of relative intake from the macronutrients fat, protein, carbohydrates, and sugar in over 235,000 individuals of European ancestries. We identified 21 unique...
BACKGROUND: ChREBP (carbohydrate responsive element binding protein) is a transcription factor that responds to sugar consumption. Sugar-sweetened beverage (SSB) consumption and genetic variants in the CHREBP locus have...
Smoking is a potentially causal behavioral risk factor for type 2 diabetes (T2D), but not all smokers develop T2D. It is unknown whether genetic factors partially explain this variation. We performed genome-environment-wide...
Macronutrient intake, the proportion of calories consumed from carbohydrate, fat, and protein, is an important risk factor for metabolic diseases with significant familial aggregation. Previous studies have identified two...
Many genetic loci affect circulating lipid levels, but it remains unknown whether lifestyle factors, such as physical activity, modify these genetic effects. To identify lipid loci interacting with physical activity, we...
AbstractUnderstanding SARS-CoV-2 transmission in higher education settings is important to limit spread between students, and into at-risk populations. In this study, we sequenced 482 SARS-CoV-2...
AbstractMitigation of SARS-CoV-2 transmission from international travel is a priority. We evaluated the effectiveness of travellers being required to quarantine for 14-days on return to England...