Search
Results: 48
SARS-CoV-2 Infects Human Pluripotent Stem Cell-Derived Cardiomyocytes, Impairing Electrical and Mechanical Function.
Silvia Marchiano, Tien-Ying Hsiang, Akshita Khanna, Ty Higashi, Leanne S Whitmore, Johannes Bargehr, Hongorzul Davaapil, Jean Chang, Elise Smith, Lay Ping Ong, Maria Colzani, Hans Reinecke, Xiulan Yang, Lil Pabon, Sanjay Sinha, Behzad Najafian, Nathan J Sniadecki, Alessandro Bertero, Michael Gale, Charles E Murry
Feb 26, 2021
COVID-19 patients often develop severe cardiovascular complications, but it remains unclear if these are caused directly by viral infection or are secondary to a systemic response. Here, we examine the cardiac tropism of...
covid-19 SARS-CoV-2 arrhythmias and heart failure cardiac infection cardiovascular disease hESC-CMs hPSC-CMs human pluripotent stem cell-derived cardiomyocytes viral myocarditis covid-19 Cells Cultured Humans Induced Pluripotent Stem Cells Myocytes Cardiac RNA Splicing RNA Messenger SARS-CoV-2 Virus Internalization
Impact of loss-to-follow-up on cancer survival estimates for small populations
Objectives: The accuracy of the ascertainment of vital status impacts the validity of cancer survival. This study assesses the potential impact of loss-to-follow-up on survival in Japan, both nationally and in the samples seen...
Evolutionary contingency as non-trivial objective probability
TY William Wong
Jan 03, 2020
Contingency-theorists have put forth differing accounts of evolutionary contingency. The bulk of these accounts abstractly refer to certain causal structures in which an evolutionarily contingent outcome is supposedly embedded....
Two Donations to Environmental Programs Expand Opportunities for Students
Winthrop University
Jan 01, 0001
Ty Robbins, a senior environmental sciences major from Clemson, South Carolina, and Allyssa Calderhead, a senior environmental studies major living in Fort Mill, are the first two Dalton Scholarship recipients. In other...
Published by: Winthrop University
Fossils Collected This Summer Will Be Subject of Tests
Winthrop University
Jan 01, 0001
Boyer and two environmental science majors, Tim Swartz and Ty Robbins, took a 13-day trip in June to Utah and Nevada to collect rock samples on federal lands believed to have been the site of mass extinctions. The Winthrop study...
Published by: Winthrop University
Negative Urgency Exacerbates Relapse to Cocaine Seeking After Abstinence.
Maxime Fouyssac, Yolanda Peña-Oliver, Mickaёl Puaud, Nicole TY Lim, Chiara Giuliano, Barry J Everitt, David Belin
Oct 15, 2021
Psychological drivers of hotel guests’ energy‐saving behaviours—empirical research based on the extended theory of planned behaviour
The hospitality industry is an important energy consumer and carbon emitter. Behaviour-driven energy conservation is a strategy with great promise to strengthen the energy efficiency of hotel buildings. The aim of this...
FBXO11 governs macrophage cell death and inflammation in response to bacterial toxins.
Yusun Jeon, Seong H Chow, Isabella Stuart, Ashley Weir, Amy TY Yeung, Christine Hale, Sushmita Sridhar, Gordon Dougan, James E Vince, Thomas Naderer
Apr 17, 2023
Staphylococcus aureus causes severe infections such as pneumonia and sepsis depending on the pore-forming toxin Panton-Valentine leukocidin (PVL). PVL kills and induces inflammation in macrophages and other myeloid cells by...
Compositional boundary layers trigger liquid unmixing in a basaltic crystal mush.
Victoria C Honour, Marian B Holness, Bernard Charlier, Sandra C Piazolo, Olivier Namur, Ty J Prosa, Isabelle Martin, Rosalind T Helz, John Maclennan, Marlon M Jean
Sep 19, 2019
The separation of immiscible liquids has significant implications for magma evolution and the formation of magmatic ore deposits. We combine high-resolution imaging and electron probe microanalysis with the first use of atom...
Mauve/LYST limits fusion of lysosome-related organelles and promotes centrosomal recruitment of microtubule nucleating proteins.
Lysosome-related organelles (LROs) are endosomal compartments carrying tissue-specific proteins, which become enlarged in Chediak-Higashi syndrome (CHS) due to mutations in LYST. Here, we show that Drosophila Mauve, a...
Chediak-Higashi syndrome Drosophila LYST centrosomes endosomal vesicle trafficking lysosome-related organelles mauve microtubule nucleation minispindles/Ch-TOG Animals Cell Line Centrosome Chediak-Higashi Syndrome Cytoplasmic Granules Drosophila Drosophila Proteins Female Humans Lysosomes Microtubule-Associated Proteins Microtubules Mutation Oocytes Spindle Apparatus Vesicular Transport Proteins
Compositional boundary layers trigger liquid unmixing in a basaltic crystal mush
Victoria C. Honour, Marian B. Holness, Bernard Charlier, Sandra C. Piazolo, Olivier Namur, Ty J. Prosa, Isabelle Martin, Rosalind T. Helz, John Maclennan, Marlon M. Jean
Oct 22, 2020
Abstract: The separation of immiscible liquids has significant implications for magma evolution and the formation of magmatic ore deposits. We combine high-resolution imaging and electron probe microanalysis with the first use...
Chile's Soft Misplaced Regional Identity
Leslie Wehner
Jul 03, 2020
This article analyses Chile’s foreign policy, utilizing a multilayered identity model, one that covers the country’s most stable identi‐ ty layer as a sovereign state, an intermediate layer in which processes of identification...
Chile's Soft Misplaced Regional Identity
Leslie Wehner
Jul 03, 2020
This article analyses Chile’s foreign policy, utilizing a multilayered identity model, one that covers the country’s most stable identi‐ ty layer as a sovereign state, an intermediate layer in which processes of identification...
Towards a Standard Psychometric Diagnostic Interview for Subjects at Ultra High Risk of Psychosis
P Fusar-Poli, M Cappucciati, G Rutigliano, TY Lee, Q Beverly, I Bonoldi, J Lelli, SJ Kaar, E Gago, M Rocchetti, R Patel, V Bhavsar, S Tognin, S Badger, M Calem, K Lim, JS Kwon, J Perez, P McGuire
Oct 03, 2017
A Genome-Wide Knockout Screen in Human Macrophages Identified Host Factors Modulating Salmonella Infection.
Amy TY Yeung, Yoon Ha Choi, Amy HY Lee, Christine Hale, Hannes Ponstingl, Derek Pickard, David Goulding, Mark Thomas, Erin Gill, Jong Kyoung Kim, Allan Bradley, Robert EW Hancock, Gordon Dougan
Oct 14, 2020
A genome-scale CRISPR knockout library screen of THP-1 human macrophages was performed to identify loss-of-function mutations conferring resistance to Salmonella uptake. The screen identified 183 candidate genes, from which 14...
Dynamic Causality Among FDI, Economic Growth and CO2 Emissions in India With Open Markets and Technology Gap
This study examines the causality relationships between FDI, economic growth (in terms of GDP) and the natural environment, in terms of CO2 emissions and energy consumption, along with two more variables of interest i.e., trade...
Published by: IGI Global Scientific Publishing
Imaging-Based Screen Identifies Laminin 411 as a Physiologically Relevant Niche Factor with Importance for i-Hep Applications.
John Ong, Maria Paola Serra, Joe Segal, Ana-Maria Cujba, Soon Seng Ng, Richard Butler, Val Millar, Stephanie Hatch, Salman Zimri, Hiroyuki Koike, Karen Chan, Andrew Bonham, Michelle Walk, Ty Voss, Nigel Heaton, Ragai Mitry, Anil Dhawan, Daniel Ebner, Davide Danovi, Hiromitsu Nakauchi, S Tamir Rashid
Mar 17, 2020
Use of hepatocytes derived from induced pluripotent stem cells (i-Heps) is limited by their functional differences in comparison with primary cells. Extracellular niche factors likely play a critical role in bridging this gap....
Reprogramming of Trypanosoma cruzi metabolism triggered by parasite interaction with the host cell extracellular matrix.
Eliciane C Mattos, Gisele Canuto, Nubia C Manchola, Rubens DM Magalhães, Thomas WM Crozier, Douglas J Lamont, Marina FM Tavares, Walter Colli, Michael AJ Ferguson, Maria Júlia M Alves
Mar 19, 2019
Trypanosoma cruzi, the etiological agent of Chagas' disease, affects 8 million people predominantly living in socioeconomic underdeveloped areas. T. cruzi trypomastigotes (Ty), the classical infective stage, interact with the...
B Cell Activation: The Regulation by T Cells and the Induction of the Protein Tyrosine Kinase SYK
Mark S Forman
Jan 01, 0001
During the activation and differentiation of B cells, there are critical stages of regulation which determine the fate of the B cell. Resting B cells are initially stimulated by either native antigen or T cells via...
Published by: Rockefeller University
Making stillbirths visible
HE Reinebrant, SH Leisher, M Coory, S Henry, AM Wojcieszek, G Gardener, R Lourie, D Ellwood, Z Teoh, E Allanson, H Blencowe, ES Draper, JJ Erwich, JF Frøen, J Gardosi, K Gold, S Gordijn, A Gordon, Aep Heazell, TY Khong, F Korteweg, JE Lawn, EM McClure, J Oats, R Pattinson, K Pettersson, D Siassakos, RM Silver, Gcs Smith, Ö Tunçalp, V Flenady
May 25, 2018
The origins and genomic diversity of American Civil War Era smallpox vaccine strains.
Ana T Duggan, Jennifer Klunk, Ashleigh F Porter, Anna N Dhody, Robert Hicks, Geoffrey L Smith, Margaret Humphreys, Andrea M McCollum, Whitni B Davidson, Kimberly Wilkins, Yu Li, Amanda Burke, Hanna Polasky, Lowell Flanders, Debi Poinar, Amogelang R Raphenya, Tammy TY Lau, Brian Alcock, Andrew G McArthur, G Brian Golding, Edward C Holmes, Hendrik N Poinar
Jul 24, 2020
Vaccination has transformed public health, most notably including the eradication of smallpox. Despite its profound historical importance, little is known of the origins and diversity of the viruses used in smallpox vaccination....
|
|< |
< |
1 |