One dimensional exponential families on finite sample spaces are studied using the geometry of the simplex Δn°-1 and that of a transformation Vn-1 of its interior. This transformation is the natural parameter space associated...
One dimensional exponential families on finite sample spaces are studied using the geometry of the simplex Δn°-1 and that of a transformation Vn-1 of its interior. This transformation is the natural parameter space associated...
Context: The DUOX2 enzyme generates hydrogen peroxide (H2O2), a crucial electron acceptor for the TPO-catalyzed iodination and coupling reactions mediating thyroid hormone biosynthesis. DUOX2 mutations result in...
Background: The mechanisms underlying acute ERK signaling are poorly understood. Results: Feedback influences basal and acutely stimulated ERK responses but does not render signaling kinetics robust to ERK concentration....
Background: Understanding the influence of stress on human performance is of theoretical and practical importance. An individual's reaction to stress predicts their subsequent performance; with a “challenge” response to...
Background: Understanding the influence of stress on human performance is of theoretical and practical importance. An individual's reaction to stress predicts their subsequent performance; with a “challenge” response to...
Background: The mechanisms underlying acute ERK signaling are poorly understood. Results: Feedback influences basal and acutely stimulated ERK responses but does not render signaling kinetics robust to ERK concentration....
Abstract: Multi-particle azimuthal cumulants are measured as a function of centrality and transverse momentum using 470 μb−1 of Pb+Pb collisions at sNN = 5.02 TeV with the ATLAS detector at the LHC. These cumulants provide...
Abstract: Multi-particle azimuthal cumulants are measured as a function of centrality and transverse momentum using 470 μb−1 of Pb+Pb collisions at sNN = 5.02 TeV with the ATLAS detector at the LHC. These cumulants provide...
Kisspeptin neurons in the arcuate nucleus of the hypothalamus generate gonadotrophin-releasing hormone (GnRH) pulses, and act as critical initiators of functional gonadotrophin secretion and reproductive competency. However...
BACKGROUND: African horse sickness virus (AHSV) causes a non-contagious, infectious disease in equids, with mortality rates that can exceed 90% in susceptible horse populations. AHSV vaccines play a crucial role in the control...
UNLABELLED: Extracellular matrix (ECM) proteins are key mediators of cell/material interactions. The surface density and conformation of these proteins adsorbed on the material surface influence cell adhesion and the cellular...
The evolution and global transmission of antimicrobial resistance have been well documented for Gram-negative bacteria and health care-associated epidemic pathogens, often emerging from regions with heavy antimicrobial use....
AbstractThe nature of dark matter and properties of neutrinos are among the most pressing issues in contemporary particle physics. The dual-phase xenon time-projection chamber is...