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Results: 74
Strikingly Different Roles of SARS-CoV-2 Fusion Peptides Uncovered by Neutron Scattering.
Andreas Santamaria, Krishna C Batchu, Olga Matsarskaia, Sylvain F Prévost, Daniela Russo, Francesca Natali, Tilo Seydel, Ingo Hoffmann, Valérie Laux, Michael Haertlein, Tamim A Darwish, Robert A Russell, Giacomo Corucci, Giovanna Fragneto, Armando Maestro, Nathan R Zaccai
Mar 18, 2022
Early Extracellular ATP Signaling in Arabidopsis Root Epidermis
Limin Wang, Gary Stacey, Nathalie Leblanc-Fournier, Valérie Legué, Bruno Moulia, Julia M Davies
Aug 19, 2019
Adenosine 5'-triphosphate (ATP) is an important extracellular signaling agent, operating in growth regulation, stomatal conductance, and wound response. With the first receptor for extracellular ATP now identified in plants...
Selective Axonal Expression of the Kv1 Channel Complex in Pre-myelinated GABAergic Hippocampal Neurons.
Giulia Bonetto, Bruno Hivert, Laurence Goutebroze, Domna Karagogeos, Valérie Crépel, Catherine Faivre-Sarrailh
Jan 02, 2020
In myelinated fibers, the voltage-gated sodium channels Nav1 are concentrated at the nodal gap to ensure the saltatory propagation of action potentials. The voltage-gated potassium channels Kv1 are segregated at the...
The electrochemical storage mechanism in oxy-hydroxyfluorinated anatase for sodium-ion batteries
Wei Li, Mika Fukunishi, Benjamin J. Morgan, Olaf J. Borkiewicz, Valérie Pralong, Antoine Maignan, Henri Groult, Shinichi Komaba, Damien Dambournet
May 01, 2018
Replacing lithium ions with sodium ions as the charge carriers in rechargeable batteries can induce noticeable differences in the electrochemical storage mechanisms of electrode materials. Many material parameters, such as...
Transdermal flux predictions for selected selective oestrogen receptor modulators (SERMs)
Sevgi Güngör, M. Begoña Delgado-Charro, Valérie Masini-Etévé, Russell O. Potts, Richard H. Guy
Dec 28, 2013
The aim of this work was to evaluate the feasibility of delivering transdermally a series of highly lipophilic compounds (log P ~ 4-7), comprising several selective oestrogen receptor modulators and a modified testosterone...
Transdermal flux predictions for selected selective oestrogen receptor modulators (SERMs)
Sevgi Güngör, M. Begoña Delgado-Charro, Valérie Masini-Etévé, Russell O. Potts, Richard H. Guy
Dec 28, 2013
The aim of this work was to evaluate the feasibility of delivering transdermally a series of highly lipophilic compounds (log P ~ 4-7), comprising several selective oestrogen receptor modulators and a modified testosterone...
Extensive NEUROG3 occupancy in the human pancreatic endocrine gene regulatory network.
Valérie Schreiber, Reuben Mercier, Sara Jiménez, Tao Ye, Emmanuel García-Sánchez, Annabelle Klein, Aline Meunier, Sabitri Ghimire, Catherine Birck, Bernard Jost, Kristian Honnens de Lichtenberg, Christian Honoré, Palle Serup, Gérard Gradwohl
Oct 19, 2021
OBJECTIVE: Mice lacking the bHLH transcription factor (TF) Neurog3 do not form pancreatic islet cells, including insulin-secreting beta cells, the absence of which leads to diabetes. In humans, homozygous mutations of NEUROG3...
A Reversible Phase Transition for Sodium Insertion in Anatase TiO<sub>2</sub>
Wei Li, Mika Fukunishi, Benjamin Morgan, Olaf Borkiewicz, Karena Chapman, Valérie Pralong, Antoine Maignan, Oleg Lebedev, Jiwei Ma, Henri Groult, Shinichi Komaba, Damien Dambournet
Feb 28, 2017
Anatase TiO2 is a potential negative electrode for sodium-ion batteries. The
sodium storage mechanism is, however, still under debate, yet its comprehension is required to optimize the electrochemical properties....
sodium storage mechanism is, however, still under debate, yet its comprehension is required to optimize the electrochemical properties....
DORN1/P2K1 and purino-calcium signalling in plants
Elsa Matthus, Jian Sun, Limin Wang, Madhura G Bhat, Amirah B Mohammad-Sidik, Katie A Wilkins, Nathalie Leblanc-Fournier, Valérie Legué, Bruno Moulia, Gary Stacey, Julia M Davies
Aug 09, 2019
A Reversible Phase Transition for Sodium Insertion in Anatase TiO<sub>2</sub>
Wei Li, Mika Fukunishi, Benjamin Morgan, Olaf Borkiewicz, Karena Chapman, Valérie Pralong, Antoine Maignan, Oleg Lebedev, Jiwei Ma, Henri Groult, Shinichi Komaba, Damien Dambournet
Feb 28, 2017
Anatase TiO2 is a potential negative electrode for sodium-ion batteries. The
sodium storage mechanism is, however, still under debate, yet its comprehension is required to optimize the electrochemical properties....
sodium storage mechanism is, however, still under debate, yet its comprehension is required to optimize the electrochemical properties....
Genome-wide identification of host-segregating epidemiological markers for source attribution in <i>Campylobacter jejuni</i>
Amandine Thépault, Guillaume Méric, Katell Rivoal, Ben Pascoe, Leonardos Mageiros, Fabrice Touzain, Valérie Rose, Véronique Béven, Marianne Chemaly, Samuel K Sheppard
Apr 01, 2017
Campylobacter is among the most common worldwide causes of bacterial gastroenteritis. This organism is part of the commensal microbiota of numerous host species, including livestock, and these animals constitute potential...
Temperate Earth-sized planets transiting a nearby ultracool dwarf star.
Michaël Gillon, Emmanuël Jehin, Susan M Lederer, Laetitia Delrez, Julien de Wit, Artem Burdanov, Valérie Van Grootel, Adam J Burgasser, Amaury HMJ Triaud, Cyrielle Opitom, Brice-Olivier Demory, Devendra K Sahu, Daniella Bardalez Gagliuffi, Pierre Magain, Didier Queloz
Jul 19, 2021
Star-like objects with effective temperatures of less than 2,700 kelvin are referred to as 'ultracool dwarfs'. This heterogeneous group includes stars of extremely low mass as well as brown dwarfs (substellar objects not massive...
DORN1/P2K1 and purino-calcium signalling in plants
Elsa Matthus, Jian Sun, Limin Wang, Madhura G Bhat, Amirah B Mohammad-Sidik, Katie A Wilkins, Nathalie Leblanc-Fournier, Valérie Legué, Bruno Moulia, Gary Stacey, Julia M Davies
Feb 06, 2020
BACKGROUND AND AIMS:Extracellular ATP governs a range of plant functions, including cell viability, adaptation and cross-kingdom interactions. Key functions of extracellular ATP in leaves and roots may involve an increase in...
Published by: Annals of botany
A novel CISD2 mutation associated with a classical Wolfram syndrome phenotype alters Ca2+ homeostasis and ER-mitochondria interactions.
Cécile Rouzier, David Moore, Cécile Delorme, Sandra Lacas-Gervais, Samira Ait-El-Mkadem, Konstantina Fragaki, Florence Burté, Valérie Serre, Sylvie Bannwarth, Annabelle Chaussenot, Martin Catala, Patrick Yu-Wai-Man, Véronique Paquis-Flucklinger
Jun 28, 2018
Wolfram syndrome (WS) is a progressive neurodegenerative disease characterized by early-onset optic atrophy and diabetes mellitus, which can be associated with more extensive central nervous system and endocrine complications....
Genome-wide identification of host-segregating epidemiological markers for source attribution in <i>Campylobacter jejuni</i>
Amandine Thépault, Guillaume Méric, Katell Rivoal, Ben Pascoe, Leonardos Mageiros, Fabrice Touzain, Valérie Rose, Véronique Béven, Marianne Chemaly, Samuel K Sheppard
Apr 01, 2017
Campylobacter is among the most common worldwide causes of bacterial gastroenteritis. This organism is part of the commensal microbiota of numerous host species, including livestock, and these animals constitute potential...
Structural and molecular determinants for the interaction of ExbB from Serratia marcescens and HasB, a TonB paralog.
Structural and molecular determinants for the interaction of ExbB from Serratia marcescens and HasB, a TonB paralog.
The electrochemical storage mechanism in oxy-hydroxyfluorinated anatase for sodium-ion batteries
Wei Li, Mika Fukunishi, Benjamin J. Morgan, Olaf J. Borkiewicz, Valérie Pralong, Antoine Maignan, Henri Groult, Shinichi Komaba, Damien Dambournet
May 01, 2018
Replacing lithium ions with sodium ions as the charge carriers in rechargeable batteries can induce noticeable differences in the electrochemical storage mechanisms of electrode materials. Many material parameters, such as...
A Missense Mutation in PPP1R15B Causes a Syndrome Including Diabetes, Short Stature, and Microcephaly.
Baroj Abdulkarim, Marc Nicolino, Mariana Igoillo-Esteve, Mathilde Daures, Sophie Romero, Anne Philippi, Valérie Senée, Miguel Lopes, Daniel A Cunha, Heather Harding, Céline Derbois, Nathalie Bendelac, Andrew T Hattersley, Décio L Eizirik, David Ron, Miriam Cnop, Cécile Julier
Jul 10, 2015
Absence of lenadogene nolparvovec DNA in a brain tumor biopsy from a patient in the REVERSE clinical study, a case report.
Nancy J Newman, Matthew Schniederjan, Pia R Mendoza, David J Calkins, Patrick Yu-Wai-Man, Valérie Biousse, Valerio Carelli, Magali Taiel, Francois Rugiero, Pramila Singh, Alexandra Rogue, José-Alain Sahel, Philippe Ancian
Jul 12, 2022
BACKGROUND: Leber Hereditary Optic Neuropathy (LHON) is a rare, maternally-inherited mitochondrial disease that primarily affects retinal ganglion cells (RGCs) and their axons in the optic nerve, leading to irreversible...
Structural and molecular determinants for the interaction of ExbB from Serratia marcescens and HasB, a TonB paralog.
Valérie Biou, Ricardo Jorge Diogo Adaixo, Mohamed Chami, Pierre-Damien Coureux, Benoist Laurent, Véronique Yvette Ntsogo Enguéné, Gisele Cardoso de Amorim, Nadia Izadi-Pruneyre, Christian Malosse, Julia Chamot-Rooke, Henning Stahlberg, Philippe Delepelaire
May 15, 2022
ExbB and ExbD are cytoplasmic membrane proteins that associate with TonB to convey the energy of the proton-motive force to outer membrane receptors in Gram-negative bacteria for iron uptake. The opportunistic pathogen Serratia...
Hypothalamic eIF2α signaling regulates food intake.
Anne-Catherine Maurin, Alexandre Benani, Anne Lorsignol, Xavier Brenachot, Laurent Parry, Valérie Carraro, Christophe Guissard, Julien Averous, Céline Jousse, Alain Bruhat, Cédric Chaveroux, Wafa B'chir, Yuki Muranishi, David Ron, Luc Pénicaud, Pierre Fafournoux
Jan 22, 2016
Structural and molecular determinants for the interaction of ExbB from Serratia marcescens and HasB, a TonB paralog
Valérie Biou, Ricardo Jorge Diogo Adaixo, Mohamed Chami, Pierre-Damien Coureux, Benoist Laurent, Véronique Yvette Ntsogo Enguéné, Gisele Cardoso de Amorim, Nadia Izadi-Pruneyre, Christian Malosse, Julia Chamot-Rooke, Henning Stahlberg, Philippe Delepelaire
Jan 19, 2023
Published by: Nature Publishing Group UK
A mitochondrial origin for frontotemporal dementia and amyotrophic lateral sclerosis through CHCHD10 involvement.
Sylvie Bannwarth, Samira Ait-El-Mkadem, Annabelle Chaussenot, Emmanuelle C Genin, Sandra Lacas-Gervais, Konstantina Fragaki, Laetitia Berg-Alonso, Yusuke Kageyama, Valérie Serre, David G Moore, Annie Verschueren, Cécile Rouzier, Isabelle Le Ber, Gaëlle Augé, Charlotte Cochaud, Françoise Lespinasse, Karine N'Guyen, Anne de Septenville, Alexis Brice, Patrick Yu-Wai-Man, Hiromi Sesaki, Jean Pouget, Véronique Paquis-Flucklinger
Mar 18, 2019
Mitochondrial DNA instability disorders are responsible for a large clinical spectrum, among which amyotrophic lateral sclerosis-like symptoms and frontotemporal dementia are extremely rare. We report a large family with a...
CHCHD10 FTD-ALS mitochondrial DNA instability mitochondrial disorder Age of Onset Aged Alleles Amyotrophic Lateral Sclerosis DNA Mitochondrial Exome Female frontotemporal dementia HeLa Cells Humans Male Middle Aged Mitochondria Mitochondrial Diseases Mitochondrial Proteins Mutation Missense Pedigree Phenotype
A Missense Mutation in PPP1R15B Causes a Syndrome Including Diabetes, Short Stature, and Microcephaly.
Baroj Abdulkarim, Marc Nicolino, Mariana Igoillo-Esteve, Mathilde Daures, Sophie Romero, Anne Philippi, Valérie Senée, Miguel Lopes, Daniel A Cunha, Heather P Harding, Céline Derbois, Nathalie Bendelac, Andrew T Hattersley, Décio L Eizirik, David Ron, Miriam Cnop, Cécile Julier
Aug 09, 2017
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