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Finite time collapsing of the Kahler-Ricci flow on threefolds
We show that if on a compact Kähler threefold there is a solution of the Kähler-Ricci flow which has finite time collapsing, then the manifold admits a Fano fibration. Furthermore, if there is finite time extinction then the...
Finite time collapsing of the Kahler-Ricci flow on threefolds
We show that if on a compact Kähler threefold there is a solution of the Kähler-Ricci flow which has finite time collapsing, then the manifold admits a Fano fibration. Furthermore, if there is finite time extinction then the...
Shared alterations in resting-state brain connectivity in adults with attention-deficit/hyperactivity disorder and their unaffected first-degree relatives.
BACKGROUND: Attention-deficit/hyperactivity disorder (ADHD) is a developmental condition that often persists into adulthood with extensive negative consequences on quality of life. Despite emerging evidence indicating the...
Attention-deficit/hyperactivity disorder Default mode network dimensional Endophenotype functional connectivity resting state sustained attention Adolescent Adult Attention Deficit Disorder with Hyperactivity Brain Case-Control Studies Connectome Endophenotypes Family Female Frontal Lobe Gyrus Cinguli Humans Magnetic Resonance Imaging Male Middle Aged Nerve Net Neural Pathways Parietal Lobe Quality of life Young Adult
Mixture Choice Data
Mixture choice data consist of the joint distribution of choices of a group of agents from a collection of menus, comprising the implied stochastic choice function plus any cross-menu correlations. When agents are heterogeneous...
Mixture Choice Data
Mixture choice data consist of the joint distribution of choices of a group of agents from a collection of menus, comprising the implied stochastic choice function plus any cross-menu correlations. When agents are heterogeneous...
Female psychopharmacology matters! Towards a sex-specific psychopharmacology
There is increasing recognition that women have a higher prevalence of certain psychiatric illnesses, and a differential treatment response and course of illness compared to men. Additionally, clinicians deal with a number of...
Sex differences allopregnanolone Estrogen Gender Neurosteroids Oxytocin Progesterone sex hormones /dk/atira/pure/subjectarea/asjc/3000/3004 name=Pharmacology /dk/atira/pure/subjectarea/asjc/2700/2738 name=Psychiatry and Mental health /dk/atira/pure/subjectarea/asjc/2700/2736 name=Pharmacology (medical) /dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_being name=SDG 3 - Good Health and Well-being
Female psychopharmacology matters! Towards a sex-specific psychopharmacology
There is increasing recognition that women have a higher prevalence of certain psychiatric illnesses, and a differential treatment response and course of illness compared to men. Additionally, clinicians deal with a number of...
Sex differences allopregnanolone Estrogen Gender Neurosteroids Oxytocin Progesterone sex hormones /dk/atira/pure/subjectarea/asjc/3000/3004 name=Pharmacology /dk/atira/pure/subjectarea/asjc/2700/2738 name=Psychiatry and Mental health /dk/atira/pure/subjectarea/asjc/2700/2736 name=Pharmacology (medical) /dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_being name=SDG 3 - Good Health and Well-being
Terahertz Frequency Combs Exploiting an On-Chip, Solution-Processed, Graphene-Quantum Cascade Laser Coupled-Cavity.
Francesco P Mezzapesa, Katia Garrasi, Johannes Schmidt, Luca Salemi, Valentino Pistore, Lianhe Li, A Giles Davies, Edmund H Linfield, Michael Riesch, Christian Jirauschek, Tian Carey, Felice Torrisi, Andrea C Ferrari, Miriam S Vitiello
Feb 19, 2021
The ability to engineer quantum-cascade-lasers (QCLs) with ultrabroad gain spectra, and with a full compensation of the group velocity dispersion, at terahertz (THz) frequencies, is key for devising monolithic and miniaturized...
Self-Induced Mode-Locking in Electrically Pumped Far-Infrared Random Lasers.
Alessandra Di Gaspare, Valentino Pistore, Elisa Riccardi, Eva AA Pogna, Harvey E Beere, David A Ritchie, Lianhe Li, Alexander Giles Davies, Edmund H Linfield, Andrea C Ferrari, Miriam S Vitiello
Jan 28, 2023
Mode locking, the self-starting synchronous oscillation of electromagnetic modes in a laser cavity, is the primary way to generate ultrashort light pulses. In random lasers, without a cavity, mode-locking, the nonlinear coupling...
Rotation in [C ii]-emitting gas in two galaxies at a redshift of 6.8.
Renske Smit, Rychard J Bouwens, Stefano Carniani, Pascal A Oesch, Ivo Labbé, Garth D Illingworth, Paul van der Werf, Larry D Bradley, Valentino Gonzalez, Jacqueline A Hodge, Benne W Holwerda, Roberto Maiolino, Wei Zheng
Jan 24, 2019
The earliest galaxies are thought to have emerged during the first billion years of cosmic history, initiating the ionization of the neutral hydrogen that pervaded the Universe at this time. Studying this 'epoch of reionization'...
Published by: Nature
Uric acid and cardiometabolic risk by gender in youth with type 1 diabetes
Abstract The aim of this study was to investigate the association between uric acid (UA) and cardiometabolic risk factors (CMRFs) by sex in youth with type 1 diabetes (T1D). Retrospective data...
Procolo Di Bonito, Francesco Maria Rosanio, Maria Loredana Marcovecchio, Valentino Cherubini, Maurizio Delvecchio, Francesca Di Candia, Dario Iafusco, Angela Zanfardino, Brunella Iovane, Claudio Maffeis, Giulio Maltoni, Carlo Ripoli, Elvira Piccinno, Claudia Anita Piona, Maria Rossella Ricciardi, Riccardo Schiaffini, Adriana Franzese, Enza Mozzillo
Jul 16, 2022
Functional electrical stimulation cycling exercise after spinal cord injury
Jan W van der Scheer, Victoria L Goosey-Tolfrey, Sydney E Valentino, Glen M Davis, Chester H Ho
Jun 22, 2021
OBJECTIVES: The objective of this review was to summarize and appraise evidence on functional electrical stimulation (FES) cycling exercise after spinal cord injury (SCI), in order to inform the development of evidence-based...
Functional electrical stimulation cycling exercise after spinal cord injury
Jan W. van der Scheer, Victoria L. Goosey-Tolfrey, Sydney E. Valentino, Glen M. Davis, Chester H. Ho
Jun 12, 2021
Abstract: Objectives: The objective of this review was to summarize and appraise evidence on functional electrical stimulation (FES) cycling exercise after spinal cord injury (SCI), in order to inform the development of...
Grafting vigour is associated with DNA de-methylation in eggplant.
Elisa Cerruti, Carmina Gisbert, Hajk-Georg Drost, Danila Valentino, Ezio Portis, Lorenzo Barchi, Jaime Prohens, Sergio Lanteri, Cinzia Comino, Marco Catoni
Jan 06, 2022
In horticulture, grafting is a popular technique used to combine positive traits from two different plants. This is achieved by joining the plant top part (scion) onto a rootstock which contains the stem and roots. Rootstocks...
Grafting vigour is associated with DNA de-methylation in eggplant.
Elisa Cerruti, Carmina Gisbert, Hajk-Georg Drost, Danila Valentino, Ezio Portis, Lorenzo Barchi, Jaime Prohens, Sergio Lanteri, Cinzia Comino, Marco Catoni
Nov 01, 2021
In horticulture, grafting is a popular technique used to combine positive traits from two different plants. This is achieved by joining the plant top part (scion) onto a rootstock which contains the stem and roots. Rootstocks...
Uric acid and cardiometabolic risk by gender in youth with type 1 diabetes.
Procolo Di Bonito, Francesco Maria Rosanio, Maria Loredana Marcovecchio, Valentino Cherubini, Maurizio Delvecchio, Francesca Di Candia, Dario Iafusco, Angela Zanfardino, Brunella Iovane, Claudio Maffeis, Giulio Maltoni, Carlo Ripoli, Elvira Piccinno, Claudia Anita Piona, Maria Rossella Ricciardi, Riccardo Schiaffini, Adriana Franzese, Enza Mozzillo
Aug 16, 2022
The aim of this study was to investigate the association between uric acid (UA) and cardiometabolic risk factors (CMRFs) by sex in youth with type 1 diabetes (T1D). Retrospective data collected from 1323 children and adolescents...
Functional electrical stimulation cycling exercise after spinal cord injury
Jan W van der Scheer, Victoria L Goosey-Tolfrey, Sydney E Valentino, Glen M Davis, Chester H Ho
Jul 28, 2021
Objectives
The objective of this review was to summarize and appraise evidence on functional electrical stimulation (FES) cycling exercise after spinal cord injury (SCI), in order to inform the development of...
spinal cord injury Exercise Systematic review clinical practice guidelines Functional electrical stimulation
Published by: Journal of neuroengineering and rehabilitation
Systematic biases in determining dust attenuation curves through galaxy SED fitting
Jianbo Qin, Xian Zhong Zheng, Min Fang, Zhizheng Pan, Stijn Wuyts, Yong Shi, Yingjie Peng, Valentino Gonzalez, Fuyan Bian, Jia-Sheng Huang, Qiu-sheng Gu, Wenhao Liu, Qinghua Tan, Dong Dong Shi, Jian Ren, Yuheng Zhang, Man Qiao, Run Wen, Shuang Liu
Mar 31, 2022
While the slope of the dust attenuation curve (δ) is found to correlate with effective dust attenuation (AV) as obtained through spectral energy distribution (SED) fitting, it remains unknown how the fitting degeneracies shape...
Systematic biases in determining dust attenuation curves through galaxy SED fitting
Jianbo Qin, Xian Zhong Zheng, Min Fang, Zhizheng Pan, Stijn Wuyts, Yong Shi, Yingjie Peng, Valentino Gonzalez, Fuyan Bian, Jia-Sheng Huang, Qiu-sheng Gu, Wenhao Liu, Qinghua Tan, Dong Dong Shi, Jian Ren, Yuheng Zhang, Man Qiao, Run Wen, Shuang Liu
Mar 31, 2022
While the slope of the dust attenuation curve (δ) is found to correlate with effective dust attenuation (AV) as obtained through spectral energy distribution (SED) fitting, it remains unknown how the fitting degeneracies shape...
Clonal expansion of mtDNA deletions
Selena Trifunov, Angela Pyle, Maria Lucia Valentino, Rocco Liguori, Patrick Yu-Wai-Man, Florence Burté, Jennifer Duff, Stephanie Kleinle, Isabel Diebold, Michela Rugolo, Rita Horvath, Valerio Carelli
Oct 03, 2018
Deletions in mitochondrial DNA (mtDNA) are an important cause of human disease and their accumulation has been implicated in the ageing process. As mtDNA is a high copy number genome, the coexistence of deleted and wild-type...
Adolescent Adult Aged Biopsy DNA Mitochondrial Electron Transport Complex IV Female GTP Phosphohydrolases Gene Dosage Genes Recessive Humans Male Middle Aged Muscle Cells Muscle Fibers Skeletal Mutation Oxidative Phosphorylation Polymerase Chain Reaction Reproducibility of Results Sequence Deletion Succinate Dehydrogenase Young Adult
The UK needs a sustainable strategy for COVID-19
Deepti Gurdasani, Laura Bear, Debby Bogaert, Rochelle A. Burgess, Reinhard Busse, Roberto Cacciola, Yves Charpak, Tim Colbourn, John Drury, Karl Friston, Valentino Gallo, Lynn Goldman, Trish Greenhalgh, Zoe Hyde, Krutika Kuppalli, Maimuna Majumder, Jose M. Martin-Moreno, Martin McKee, Susan Michie, Elias Mossialos, Ali Nouri, Christina Pagel, Dominic Pimenta, Saskia Popescu, Viola Priesemann, Angela L. Rasmussen, Stephen Reicher, Walter Ricciardi, Ken Rice, Joshua Silver, Tara C. Smith, Clare Wenham, Robert West, Gavin Yarney, Kit Yates, Hisham Ziauddeen
Dec 05, 2020
The UK is well into the second wave of COVID-19, with 60 051 lives lost to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection to date, according to provisional data from the Office for National Statistics....
The UK needs a sustainable strategy for COVID-19
Deepti Gurdasani, Laura Bear, Debby Bogaert, Rochelle A. Burgess, Reinhard Busse, Roberto Cacciola, Yves Charpak, Tim Colbourn, John Drury, Karl Friston, Valentino Gallo, Lynn Goldman, Trish Greenhalgh, Zoe Hyde, Krutika Kuppalli, Maimuna Majumder, Jose M. Martin-Moreno, Martin McKee, Susan Michie, Elias Mossialos, Ali Nouri, Christina Pagel, Dominic Pimenta, Saskia Popescu, Viola Priesemann, Angela L. Rasmussen, Stephen Reicher, Walter Ricciardi, Ken Rice, Joshua Silver, Tara C. Smith, Clare Wenham, Robert West, Gavin Yarney, Kit Yates, Hisham Ziauddeen
Dec 05, 2020
The UK is well into the second wave of COVID-19, with 60 051 lives lost to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection to date, according to provisional data from the Office for National Statistics....
Genetic determinants of survival in progressive supranuclear palsy
Edwin Jabbari, Shunsuke Koga, Rebecca R Valentino, Regina H Reynolds, Raffaele Ferrari, Manuela MX Tan, James B Rowe, Clifton L Dalgard, Sonja W Scholz, Dennis W Dickson, Thomas T Warner, Tamas Revesz, Günter U Höglinger, Owen A Ross, Mina Ryten, John Hardy, Maryam Shoai, Huw R Morris, PSP Genetics Group
Jan 21, 2021
BACKGROUND: The genetic basis of variation in the progression of primary tauopathies has not been determined. We aimed to identify genetic determinants of survival in progressive supranuclear palsy (PSP). METHODS: In stage one...
Adult Age of Onset Aged Chromosomes Human Pair 12 Databases Genetic Female Genetic Predisposition to Disease genetic variation Genome-Wide Association Study Humans Kaplan-Meier Estimate Leucine-Rich Repeat Serine-Threonine Protein Kinase-2 Linkage Disequilibrium Male Middle Aged Polymorphism Single Nucleotide RNA Long Noncoding Supranuclear Palsy Progressive Survival Analysis White People
Multi-system neurological disease is common in patients with OPA1 mutations.
P Yu-Wai-Man, PG Griffiths, GS Gorman, CM Lourenco, AF Wright, M Auer-Grumbach, A Toscano, O Musumeci, ML Valentino, L Caporali, C Lamperti, CM Tallaksen, P Duffey, J Miller, RG Whittaker, MR Baker, MJ Jackson, MP Clarke, B Dhillon, B Czermin, JD Stewart, G Hudson, P Reynier, D Bonneau, W Marques, G Lenaers, R McFarland, RW Taylor, DM Turnbull, M Votruba, M Zeviani, V Carelli, LA Bindoff, R Horvath, P Amati-Bonneau, PF Chinnery
Mar 07, 2019
Additional neurological features have recently been described in seven families transmitting pathogenic mutations in OPA1, the most common cause of autosomal dominant optic atrophy. However, the frequency of these syndromal...
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