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Intracellular screening of a peptide library to derive a potent peptide inhibitor of α-synuclein aggregation
Aggregation of α-synuclein (α-syn) into toxic fibrils is a pathogenic hallmark of Parkinson's disease (PD). Studies have largely focused on residues 71-82, yet most early onset mutations are located between residues 46-53. A...
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Intracellular screening of a peptide library to derive a potent peptide inhibitor of α-synuclein aggregation
Aggregation of α-synuclein (α-syn) into toxic fibrils is a pathogenic hallmark of Parkinson's disease (PD). Studies have largely focused on residues 71-82, yet most early onset mutations are located between residues 46-53. A...
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Frederick M. Allen, 1916
Frederick M. Allen, M.D. The Role of Fat in Diabetes. Delivered November 4th, 1916
Published by: J.B. Lippincott Company
The Ursinus Weekly, November 9, 1925
Ursinus campaign opens with liberal response Student campaign a big success Varsity defeated by Swarthmore Campaign to help Ursinus enlarge in church work Old rivals to battle at Lancaster on Saturday Hockey team ties...
Published by: Ursinus College
Variations in whole brain radiation therapy fractionation for brain metastases in Victoria.
INTRODUCTION: We aim to evaluate the use of different whole brain radiation therapy (WBRT) fractionation schedules for brain metastases (BM) in Victoria, and the factors associated with it. METHODS: This is a population-based...
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Energy minimisers of prescribed winding number in an S<sup>1</sup>-valued nonlocal Allen-Cahn type model
Radu Ignat, Roger Moser
Dec 01, 2019

We study a variational model for transition layers with an underlying functional that combines an Allen-Cahn type structure with an additional nonlocal interaction term. A transition layer is represented by a map from R to S...

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Genomics of Parallel Ecological Speciation in Lake Victoria Cichlids.
The genetic basis of parallel evolution of similar species is of great interest in evolutionary biology. In the adaptive radiation of Lake Victoria cichlid fishes, sister species with either blue or red-back male nuptial...
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Energy minimisers of prescribed winding number in an S<sup>1</sup>-valued nonlocal Allen-Cahn type model
Radu Ignat, Roger Moser
Dec 01, 2019

We study a variational model for transition layers with an underlying functional that combines an Allen-Cahn type structure with an additional nonlocal interaction term. A transition layer is represented by a map from R to S...

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Hydration and N-acetyl-l-cysteine alter the microstructure of human nail and bovine hoof
This work aimed to (a) characterize the microstructure and porosity of human nail and bovine hoof by mercury intrusion porosimetry and SEM image analysis, (b) study the effects of hydration and of N-acetyl-l-cysteine treatment...
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Hydration and N-acetyl-l-cysteine alter the microstructure of human nail and bovine hoof
This work aimed to (a) characterize the microstructure and porosity of human nail and bovine hoof by mercury intrusion porosimetry and SEM image analysis, (b) study the effects of hydration and of N-acetyl-l-cysteine treatment...
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Corinna PMG 655 (= P.Oxy. 2370) fr.1 l. 13 κόσμ[εισα λόγυ]ς
L Prauscello
May 02, 2017
0. Fr. 1 of P.Oxy. 2370 (= MP3 249; LDAB 573), published by Lobel in 1956, is so far the only papyrus fragment among those extant in Boeotian dialect1 whose authorship can be securely ascribed to Corinna thanks to the overlap...
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Floer Simple Manifolds and L-Space Intervals
J Rasmussen, SD Rasmussen
Feb 26, 2018
An oriented three-manifold with torus boundary admits either no L-space Dehn filling, a unique L-space filling, or an interval of L-space fillings. In the latter case, which we call “Floer simple,” we construct an invariant...
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L q -spectra of self-affine measures
Abstract: We study L q -spectra of planar self-affine measures generated by diagonal matrices. We introduce a new technique for constructing and understanding examples based on combinatorial estimates for the exponential growth...
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S-2-Amino-4-cyanobutanoic acid (β-cyanomethyl-L-Ala) as an atom-efficient solubilising synthon for L-glutamine
Glutamine (Gln) is often a difficult amino acid to incorporate during solution-phase peptide synthesis, owing to poor solubility and unwanted dehydrations as side-reactions. Current approaches to solving these problems are...
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Using working memory performance to predict mathematics performance 2 years on.
A number of previous studies have used working memory components to predict mathematical performance in a variety of ways; however, there is no consideration of the contributions of the subcomponents of visuospatial working...
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The Ursinus Weekly, May 18, 1925
Music students render concerts "Old Sol" smiles on large crowd that gathers to view May Day festivities Ursinus bears register victory over Drexel, but are defeated by Lehigh Ursinus tennis team trounces St. Joe men 6-0 ...
Published by: Ursinus College
Frank L. Horsfall, Jr., 1952
Frank L. Horsfall, Jr. Experiments on chemical alteration of virus infections. Lecture delivered November 20, 1952 Posted with permission
Alumna Establishes Endowed Fund to Support Pre-Physical Therapy Students
Winthrop University
Jan 01, 0001
Dorothy "Dot" Allen established the Dorothy B. Allen Endowed Fund to support Winthrop's pre-physical therapy program. Allen worked as a physical therapist and traveled the world in the U.S. Army Reserves Medical Corps.
Published by: Winthrop University
The Ursinus Weekly, February 22, 1926
Zwinglian Society selects play cast Women's affirmative debating team defeats Bucknell Dr. Oliver Russell to speak March 9 Men's affirmative debating team defeats Juniata Schaff presents play on Friday Adanac Quartet...
Published by: Ursinus College
Rapid sensing of l-leucine by human and murine hypothalamic neurons
OBJECTIVE: Dietary proteins are sensed by hypothalamic neurons and strongly influence multiple aspects of metabolic health, including appetite, weight gain, and adiposity. However, little is known about the mechanisms by which...
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S-2-Amino-4-cyanobutanoic acid (β-cyanomethyl-L-Ala) as an atom-efficient solubilising synthon for L-glutamine
Glutamine (Gln) is often a difficult amino acid to incorporate during solution-phase peptide synthesis, owing to poor solubility and unwanted dehydrations as side-reactions. Current approaches to solving these problems are...
Published by:
Microbial regulation of the L cell transcriptome.
L cells are an important class of enteroendocrine cells secreting hormones such as glucagon like peptide-1 and peptide YY that have several metabolic and physiological effects. The gut is home to trillions of bacteria affecting...
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