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IN MEMORY OF VINCENT DOLE
The Rockefeller University
Jan 01, 0001
A Scientific Symposium in Memory of Vincent P. Dole
See Dole, Vincent P.
Published by: The Rockefeller University
Metabolic synthetic lethality in cancer therapy
Antimetabolites Antineoplastic Computer Simulation Energy Metabolism Forecasting Gene Dosage Gene Silencing Genes Neoplasm Humans Metabolome Mitochondria Mitochondrial Proteins Models Biological Molecular Targeted Therapy Neoplasm Proteins Neoplasms Oncogenes Oxidative Phosphorylation RNA Interference Synthetic Lethal Mutations
Intestinal activation of Notch signaling induces rapid onset hepatic steatosis and insulin resistance.
Here we investigate the effects of expressing an activated mutant of Notch (ICD-E) in an inducible transgenic mouse model. Hepatic expression of ICD-E in adult animals has no detectable phenotype, but simultaneous induction of...
Fumarate is an epigenetic modifier that elicits epithelial-to-mesenchymal transition.
Marco Sciacovelli, Emanuel Gonçalves, Timothy Isaac Johnson, Vincent Roberto Zecchini, Ana Sofia Henriques da Costa, Edoardo Gaude, Alizee Vercauteren Drubbel, Sebastian Julian Theobald, Sandra Riekje Abbo, Maxine Gia Binh Tran, Vinothini Rajeeve, Simone Cardaci, Sarah Foster, Haiyang Yun, Pedro Cutillas, Anne Warren, Vincent Gnanapragasam, Eyal Gottlieb, Kristian Franze, Brian Huntly, Eamonn Richard Maher, Patrick Henry Maxwell, Julio Saez-Rodriguez, Christian Frezza
Sep 30, 2016
Nuclear ARRB1 induces pseudohypoxia and cellular metabolism reprogramming in prostate cancer.
Vincent Zecchini, Basetti Madhu, Roslin Russell, Nelma Pértega-Gomes, Anne Warren, Edoardo Gaude, Joana Borlido, Rory Stark, Heather Ireland-Zecchini, Roheet Rao, Helen Scott, Joan Boren, Charlie Massie, Mohammad Asim, Kevin Brindle, John Griffiths, Christian Frezza, David E Neal, Ian G Mills
Nov 16, 2017
Tumour cells sustain their high proliferation rate through metabolic reprogramming, whereby cellular metabolism shifts from oxidative phosphorylation to aerobic glycolysis, even under normal oxygen levels. Hypoxia-inducible...
adaptor Hypoxia metabolism Prostate Transcription Arrestins Chromatin Immunoprecipitation Fluorescent Antibody Technique Fumarate Hydratase Gas Chromatography-Mass Spectrometry Gene Expression Profiling Humans Hypoxia-Inducible Factor 1 alpha Subunit Immunoblotting Immunohistochemistry Magnetic Resonance Spectroscopy Male Metabolic Networks and Pathways Metabolomics Models Biological Prostatic Neoplasms RNA Interference Succinate Dehydrogenase Tissue Array Analysis beta-Arrestin 1 beta-Arrestins
The Mass Incarceration of Undocumented Latinos/as in the Prison-Immigration Industrial Complex
Roberto Velasquez
Nov 17, 2016
In this chapter, the authors discuss the current mass incarceration of Latinos/as in the United States. While Latinos/as have always been overrepresented in the criminal justice system, especially in relation to their population...
Published by: IGI Global Scientific Publishing
The Parkinson's disease protein LRRK2 impairs proteasome substrate clearance without affecting proteasome catalytic activity.
Leucine-rich repeat kinase 2 (LRRK2) mutations are the most common known cause of Parkinson's disease (PD). The clinical features of LRRK2 PD are indistinguishable from idiopathic PD, with accumulation of α-synuclein and/or tau...
Animals Biocatalysis Cell Line HSP70 Heat-Shock Proteins Humans Leucine-Rich Repeat Serine-Threonine Protein Kinase-2 Models Animal Parkinson Disease Proteasome Endopeptidase Complex Protein Serine-Threonine Kinases Signal Transduction Substrate Specificity Transcription Genetic Ubiquitin Zebrafish ALPHA-SYNUCLEIN
A Cloud-KPIs Dashboard to Evaluate Agile Development Teams' Performance
In agile software development, the performance of human development teams is pivotal for project success, yet assessing their performance can be challenging, given the flexibility of agile project management. This article...
Published by: IGI Global Scientific Publishing
Dynamic partitioning of branched-chain amino acids-derived nitrogen supports renal cancer progression.
Marco Sciacovelli, Aurelien Dugourd, Lorea Valcarcel Jimenez, Ming Yang, Efterpi Nikitopoulou, Ana SH Costa, Laura Tronci, Veronica Caraffini, Paulo Rodrigues, Christina Schmidt, Dylan Gerard Ryan, Timothy Young, Vincent R Zecchini, Sabrina H Rossi, Charlie Massie, Caroline Lohoff, Maria Masid, Vassily Hatzimanikatis, Christoph Kuppe, Alex Von Kriegsheim, Rafael Kramann, Vincent Gnanapragasam, Anne Y Warren, Grant D Stewart, Ayelet Erez, Sakari Vanharanta, Julio Saez-Rodriguez, Christian Frezza
Jan 22, 2023
Metabolic reprogramming is critical for tumor initiation and progression. However, the exact impact of specific metabolic changes on cancer progression is poorly understood. Here, we integrate multimodal analyses of primary and...
Parenting and child mental health during the COVID-19 pandemic
COVID-19 and the subsequent public health response created many additional stresses for families. We examined parental behaviour during the COV-ID-19 pandemic in two European Countries and explored the association between...
child’s anxiety child’s quality of life covid-19 Parenting /dk/atira/pure/subjectarea/asjc/2700/2735 name=Pediatrics, Perinatology, and Child Health /dk/atira/pure/subjectarea/asjc/3200/3205 name=Experimental and Cognitive Psychology /dk/atira/pure/subjectarea/asjc/3200/3204 name=Developmental and Educational Psychology /dk/atira/pure/subjectarea/asjc/3200/3203 name=Clinical Psychology /dk/atira/pure/subjectarea/asjc/2700/2738 name=Psychiatry and Mental health /dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_being name=SDG 3 - Good Health and Well-being
A Tribute to Philip McShane
Robert Gerard Henman
Mar 16, 2022
Robert Henman lectured in philosophy, ethics, Child Studies, and Peace Studies at Mount St. Vincent University, Halifax, Canada for 35 years. He is the author of The Child as Quest (University Press of America, 1984), Global...
Published by: Memorial University of Newfoundland
Parenting and child mental health during the COVID-19 pandemic
COVID-19 and the subsequent public health response created many additional stresses for families. We examined parental behaviour during the COV-ID-19 pandemic in two European Countries and explored the association between...
child’s anxiety child’s quality of life covid-19 Parenting /dk/atira/pure/subjectarea/asjc/2700/2735 name=Pediatrics, Perinatology, and Child Health /dk/atira/pure/subjectarea/asjc/3200/3205 name=Experimental and Cognitive Psychology /dk/atira/pure/subjectarea/asjc/3200/3204 name=Developmental and Educational Psychology /dk/atira/pure/subjectarea/asjc/3200/3203 name=Clinical Psychology /dk/atira/pure/subjectarea/asjc/2700/2738 name=Psychiatry and Mental health /dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_being name=SDG 3 - Good Health and Well-being
Fumarate induces vesicular release of mtDNA to drive innate immunity
Vincent Zecchini, Vincent Paupe, Irene Herranz-Montoya, Joëlle Janssen, Inge M. N. Wortel, Jordan L. Morris, Ashley Ferguson, Suvagata Roy Chowdury, Marc Segarra-Mondejar, Ana S. H. Costa, Gonçalo C. Pereira, Laura Tronci, Timothy Young, Efterpi Nikitopoulou, Ming Yang, Dóra Bihary, Federico Caicci, Shun Nagashima, Alyson Speed, Kalliopi Bokea, Zara Baig, Shamith Samarajiwa, Maxine Tran, Thomas Mitchell, Mark Johnson, Julien Prudent, Christian Frezza
Mar 15, 2023
A Tribute to Philip McShane
Robert Gerard Henman
Mar 16, 2022
Robert Henman lectured in philosophy, ethics, Child Studies, and Peace Studies at Mount St. Vincent University, Halifax, Canada for 35 years. He is the author of The Child as Quest (University Press of America, 1984), Global...
Published by: Memorial University of Newfoundland
Trick Or Treat: Halloween Events Sure to Terrify the Campus
Winthrop University
Jan 01, 0001
Horror films, pumpkin carving and the annual "fiend fest" highlight this year's Halloween-related events at Winthrop University. Brush up on your Vincent Price impression with a free showing of House on Haunted Hill. The film is...
Published by: Winthrop University
State Political Experts Gather Aug. 21 to Discuss Gubernatorial Election
Winthrop University
Jan 01, 0001
Huffmon and four other scholars will talk about this year's rematch between incumbent Gov. Nikki Haley and challenger Sen. Vincent Sheheen. The symposium, hosted by USC's College of Arts and Sciences and the political science...
Published by: Winthrop University
Lessons learned from the development and implementation of a patient-reported outcome and experience measure (POEM) in an Australian glaucoma practice.
Alison Fraenkel, Graham A Lee, Stephen J Vincent, Roslyn A Vincent, Rupert RA Bourne, Peter Shah
Aug 21, 2020
BACKGROUND: A patient's perception of how their glaucoma is managed will influence both adherence to their medication and outcome measures such as quality of life. METHODS: Prospective consecutive study using a Glaucoma...
Glaucoma Patient engagement Patient-reported outcome experience measure Activities of Daily Living Adult Aged Aged 80 and over Cross-Sectional Studies Female Glaucoma Humans Intraocular Pressure Male Middle Aged Morbidity Patient Reported Outcome Measures Prospective Studies Quality of Health Care Quality of life Queensland Surveys and Questionnaires Visual Acuity Visual Fields Young Adult
Chondrocyte outgrowth into a gelatin scaffold in a single impact load model of damage/repair - effect of BMP-2.
Alterations in the vimentin cytoskeleton in response to single impact load in an in vitro model of cartilage damage in the rat.
Fenômica
Computer vision and image processing procedures could obtain crop data frequently and precisely, such as vegetation indexes, and correlating them with other variables, like biomass and crop yield. This work presents the...
Published by: IGI Global Scientific Publishing
Busy In The Meadow: [Dr. Vincent Dole]
Rockefeller University Research Profiles are a series of scientific profiles that were published quarterly, from 1980-1990, by the Rockefeller University. Each issue features the research and achievements of an individual...
Dole Vincent Rockefeller University Scientists Rockefeller University Hospital methadone maintenance Heroin addiction Van Slyke Donald Nyswander Marie Life Sciences
Published by: The Rockefeller University
The Grizzly, February 19, 2009
Kristi Blust, Gabrielle Poretta, Michael Wasserman, Liz Kilmer, Jeremiah Long, Caitlin Dalik, Eva Bramesco, Serena Mithboakar, Chris Capone, Spencer Jones, Zach Shamberg, Jameson Cooper, Frank Martin
Jan 01, 0001
Opening Minds and Hearts Alumni Advice Lecturer Dr. Andrew Delbanco Reviews Lincoln Now and Then Thai Spice is Giving You a Taste of a Different Part of Asia Sexually Transmitted Diseases: Cautionary Reminder Fresh Talent...
Ursinus College Collegeville Pennsylvania newspaper Jennifer Finney Boylan Mike McGarvey Andrew Delbanco Heather Dougherty dance Vincent Brousse cultural history Higher Education Liberal Studies Social History United States History
Published by: Ursinus College
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