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Biophysical Tools and Concepts Enable Understanding of Asexual Blood Stage Malaria.
Forces and mechanical properties of cells and tissues set constraints on biological functions, and are key determinants of human physiology. Changes in cell mechanics may arise from disease, or directly contribute to...
Evidence against a Role of Elevated Intracellular Ca2+ during Plasmodium falciparum Preinvasion.
Viola Introini, Alex Crick, Teresa Tiffert, Jurij Kotar, Yen-Chun Lin, Pietro Cicuta, Virgilio L Lew
May 16, 2018
Severe malaria is primarily caused by Plasmodium falciparum parasites during their asexual reproduction cycle within red blood cells. One of the least understood stages in this cycle is the brief preinvasion period during which...
Cell Anomaly Localisation using Structured Uncertainty Prediction Networks
Boyko Vodenicharski, Samuel McDermott, Katherine Webber, Viola Introini, Pietro Cicuta, Richard Bowman, Ivor J.A. Simpson, Neill D.F. Campbell
Jul 08, 2022
This paper proposes an unsupervised approach to anomaly detection in bright-field or fluorescence cell microscopy, where our goal is to localise malaria parasites. This is achieved by building a generative model (a...
Cell Anomaly Localisation using Structured Uncertainty Prediction Networks
Boyko Vodenicharski, Samuel McDermott, Katherine Webber, Viola Introini, Pietro Cicuta, Richard Bowman, Ivor J.A. Simpson, Neill D.F. Campbell
Jul 08, 2022
This paper proposes an unsupervised approach to anomaly detection in bright-field or fluorescence cell microscopy, where our goal is to localise malaria parasites. This is achieved by building a generative model (a...
The erythrocyte membrane properties of beta thalassaemia heterozygotes and their consequences for Plasmodium falciparum invasion.
Viola Introini, Alejandro Marin-Menendez, Guilherme Nettesheim, Yen-Chun Lin, Silvia N Kariuki, Adrian L Smith, Letitia Jean, John N Brewin, David C Rees, Pietro Cicuta, Julian C Rayner, Bridget S Penman
Jun 29, 2022
Malaria parasites such as Plasmodium falciparum have exerted formidable selective pressures on the human genome. Of the human genetic variants associated with malaria protection, beta thalassaemia (a haemoglobinopathy) was the...
Red blood cell tension protects against severe malaria in the Dantu blood group.
Silvia N Kariuki, Alejandro Marin-Menendez, Viola Introini, Benjamin J Ravenhill, Yen-Chun Lin, Alex Macharia, Johnstone Makale, Metrine Tendwa, Wilfred Nyamu, Jurij Kotar, Manuela Carrasquilla, J Alexandra Rowe, Kirk Rockett, Dominic Kwiatkowski, Michael P Weekes, Pietro Cicuta, Thomas N Williams, Julian C Rayner
Sep 15, 2020
The erythrocyte membrane properties of beta thalassaemia heterozygotes and their consequences for Plasmodium falciparum invasion.
Roto++
Rotoscoping (cutting out different characters/objects/layers in raw video footage) is a ubiquitous task in modern post-production and represents a significant investment in person-hours. In this work, we study the particular...
Introduction
Funder: Università degli Studi Roma Tre
Roto++
Rotoscoping (cutting out different characters/objects/layers in raw video footage) is a ubiquitous task in modern post-production and represents a significant investment in person-hours. In this work, we study the particular...
Unsteady load mitigation through a passive trailing-edge flap
There are a wide range of applications in which it is desirable to mitigate unsteady load fluctuations while preserving mean loading. This is often achieved with active control systems, but passive systems are sometimes more...
Interview with Horace Goggins
Horace Goggins
Jan 01, 0001
In his April 29, 1981 interview with Viola Sherrill, Horace Goggins shares the story of how he became a dentist, his involvement in the Civil Rights Movement, and how he supports his wife's political career. This interview was...
Friendship College Dentistry organizations Integration of Winthrop Wife in Politics NAACP Oral History
Published by: Winthrop University
“Only the orangutans get a life jacket”
ABSTRACT: In an era of mass extinction, who gets a life jacket, who is left to drown or swim—and on what basis? This article addresses these questions by analyzing how tropes and practices of responsibility are variously...
Published by: American Ethnologist
Unsteady load mitigation through a passive trailing-edge flap
There are a wide range of applications in which it is desirable to mitigate unsteady load fluctuations while preserving mean loading. This is often achieved with active control systems, but passive systems are sometimes more...
The Grizzly, September 19, 2019
Kevin Leon, Samuel Chiche, Rosalia Murphy, Kim Corona, Colleen Murphy, Jenni Berrios, Daniel Walker, Elana Goldman, Gabriela Howell, Lauren Viola
Jan 01, 0001
Two Decades of Ursinus Fringe Festival Professor Walvoord Wins First-Year Advising Award Men's Golf Competes at Spartan Invitational Shammah Bermudez Will Depart from Ursinus Res Life Launches "It's On Me" Campaign Wismer...
Ursinus College Collegeville Pennsylvania newspaper fringe festival Ryan Walvoord golf Shammah Bermudez disability services Residence Life Wismer on Wheels Football field hockey cultural history Higher Education Liberal Studies Social History United States History
Published by: Ursinus College
Enabling Interoperability in the Internet of Things
Semantic Web technologies act as an interoperability glue among different formats, protocols and platforms, providing a uniform vision of heterogeneous devices and services in the Internet of Things (IoT). Semantic Web...
Published by: IGI Global Scientific Publishing
The Grizzly, September 12, 2019
Kevin Leon, Katherine Chicano, Kim Corona, Rosalia Murphy, Madison Rodak, Colleen Murphy, Jenni Berrios, Daniel Walker, Lauren Viola, Gabriela Howell
Jan 01, 0001
The Commons is Coming Ursinus Celebrates its 150th Birthday High Expectations for Women's Field Hockey Proposal Submission Deadline for Ursinus' Inclusive Community Grants is Approaching Berman Exhibit Lands on Campus Who...
Ursinus College Collegeville Pennsylvania newspaper Schellhase Commons sesquicentennial field hockey Diversity Berman Art Museum Rob Coyle Soccer Tom Garlick cultural history Higher Education Liberal Studies Social History United States History
Published by: Ursinus College
The Ursinus Weekly, December 1, 1941
Prince Zu Loewenstein, German exile, will speak at first forum Wednesday Handel's "Messiah" to open Christmas season at Ursinus Artists to present viola-piano recital here Wednesday 'Know your Money' is title of G-man movie...
Ursinus College Collegeville Pennsylvania newspaper debate team Beardwood Chemical Society pre-medical society Hubertus Zu Loewenstein Music Club Bill Power Basketball Football Eleanor Snell cultural history Higher Education Liberal Studies Social History United States History
Published by: Ursinus College
Neurodegenerative disease of the brain
Franca Davenport, John Gallacher, Zoe Kourtzi, Ivan Koychev, Paul M Matthews, Neil P Oxtoby, Laura M Parkes, Viola Priesemann, James B Rowe, Stephen W Smye, Henrik Zetterberg
Feb 17, 2023
Neurodegenerative diseases of the brain pose a major and increasing global health challenge, with only limited progress made in developing effective therapies over the last decade. Interdisciplinary research is improving...
Microfluidic characterisation reveals broad range of SARS-CoV-2 antibody affinity in human plasma.
Matthias M Schneider, Marc Emmenegger, Catherine K Xu, Itzel Condado Morales, Georg Meisl, Priscilla Turelli, Chryssa Zografou, Manuela R Zimmermann, Beat M Frey, Sebastian Fiedler, Viola Denninger, Raphaël PB Jacquat, Lidia Madrigal, Alison Ilsley, Vasilis Kosmoliaptsis, Heike Fiegler, Didier Trono, Tuomas PJ Knowles, Adriano Aguzzi
Jan 10, 2022
A comparison of MEmory Specificity Training (MEST) to education and support (ES) in the treatment of recurrent depression
Tim Dalgleish, Anna Bevan, Anna McKinnon, Lauren Breakwell, Viola Mueller, Isobel Chadwick, Susanne Schweizer, Caitlin Hitchcock, Peter Watson, Filip Raes, Laura Jobson, Aliza Werner-Seidler
Aug 03, 2018
BACKGROUND: Depression is a debilitating mental health problem that tends to run a chronic, recurrent course. Even when effectively treated, relapse and recurrence rates remain high. Accordingly, interventions need to focus not...
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