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Results: 6
Socio-economic inequalities in glycaemic control in recently diagnosed adults with type 1 and type 2 diabetes.
Esther Seidel-Jacobs, Violetta Ptushkina, Klaus Strassburger, Andrea Icks, Oliver Kuss, Volker Burkart, Julia Szendroedi, Karsten Müssig, Kálmán Bódis, Yanislava Karusheva, Oana-Patricia Zaharia, Michael Roden, Wolfgang Rathmann, GDS Group
Mar 31, 2022
Direct Transcriptional Consequences of Somatic Mutation in Breast Cancer.
Adam Shlien, Keiran Raine, Fabio Fuligni, Roland Arnold, Serena Nik-Zainal, Serge Dronov, Lira Mamanova, Andrej Rosic, Young Seok Ju, Susanna L Cooke, Manasa Ramakrishna, Elli Papaemmanuil, Helen R Davies, Patrick S Tarpey, Peter Van Loo, David C Wedge, David R Jones, Sancha Martin, John Marshall, Elizabeth Anderson, Claire Hardy, Oslo Breast Cancer Research Consortium ICGC Breast Cancer Working Group, Violetta Barbashina, Samuel AJR Aparicio, Torill Sauer, Øystein Garred, Anne Vincent-Salomon, Odette Mariani, Sandrine Boyault, Aquila Fatima, Anita Langerød, Åke Borg, GIlles Thomas, Andrea L Richardson, Anne-Lise Børresen-Dale, Kornelia Polyak, Michael R Stratton, Peter J Campbell
Nov 01, 2018
Disordered transcriptomes of cancer encompass direct effects of somatic mutation on transcription, coordinated secondary pathway alterations, and increased transcriptional noise. To catalog the rules governing how somatic...
Maps of Constitutive-Heterochromatin Distribution for Four Martes Species (Mustelidae, Carnivora, Mammalia) Show the Formative Role of Macrosatellite Repeats in Interspecific Variation of Chromosome Structure.
Violetta R Beklemisheva, Natalya A Lemskaya, Dmitry Yu Prokopov, Polina L Perelman, Svetlana A Romanenko, Anastasia A Proskuryakova, Natalya A Serdyukova, Yaroslav A Utkin, Wenhui Nie, Malcolm A Ferguson-Smith, Fentang Yang, Alexander S Graphodatsky
Mar 06, 2023
Maps of Constitutive-Heterochromatin Distribution for Four <i>Martes</i> Species (Mustelidae, Carnivora, Mammalia) Show the Formative Role of Macrosatellite Repeats in Interspecific Variation of Chromosome Structure.
Violetta R Beklemisheva, Natalya A Lemskaya, Dmitry Yu Prokopov, Polina L Perelman, Svetlana A Romanenko, Anastasia A Proskuryakova, Natalya A Serdyukova, Yaroslav A Utkin, Wenhui Nie, Malcolm A Ferguson-Smith, Fentang Yang, Alexander S Graphodatsky
Mar 28, 2023
Constitutive-heterochromatin placement in the genome affects chromosome structure by occupying centromeric areas and forming large blocks. To investigate the basis for heterochromatin variation in the genome, we chose a group of...
Stone marten Sable fluorescence in situ hybridization Rdna Probe Pine Marten Yellow-throated Marten Telomere Repeat Tandemly Arranged Sequences Cdag Staining Macrosatellite Dna Chromosome Structures Euchromatin Heterochromatin Animals Carnivora Mustelidae In Situ Hybridization Fluorescence
Published by: Genes
Impact of spliceosome mutations on RNA splicing in myelodysplasia
Andrea Pellagatti, Richard N Armstrong, Violetta Steeples, Eshita Sharma, Emmanouela Repapi, Shalini Singh, Andrea Sanchi, Aleksandar Radujkovic, Patrick Horn, Hamid Dolatshad, Swagata Roy, John Broxholme, Helen Lockstone, Stephen Taylor, Aristoteles Giagounidis, Paresh Vyas, Anna Schuh, Angela Hamblin, Elli Papaemmanuil, Sally Killick, Luca Malcovati, Marco L Hennrich, Anne-Claude Gavin, Anthony D Ho, Thomas Luft, Eva Hellström-Lindberg, Mario Cazzola, Christopher WJ Smith, Stephen Smith, Jacqueline Boultwood
Mar 19, 2019
SF3B1, SRSF2, and U2AF1 are the most frequently mutated splicing factor genes in the myelodysplastic syndromes (MDS). We have performed a comprehensive and systematic analysis to determine the effect of these commonly mutated...
Chronic Activation of γ2 AMPK Induces Obesity and Reduces β Cell Function.
Arash Yavari, Claire J Stocker, Sahar Ghaffari, Edward T Wargent, Violetta Steeples, Gabor Czibik, Katalin Pinter, Mohamed Bellahcene, Angela Woods, Pablo B Martínez de Morentin, Céline Cansell, Brian YH Lam, André Chuster, Kasparas Petkevicius, Marie-Sophie Nguyen-Tu, Aida Martinez-Sanchez, Timothy J Pullen, Peter L Oliver, Alexander Stockenhuber, Chinh Nguyen, Merzaka Lazdam, Jacqueline F O'Dowd, Parvathy Harikumar, Mónika Tóth, Craig Beall, Theodosios Kyriakou, Julia Parnis, Dhruv Sarma, George Katritsis, Diana DJ Wortmann, Andrew R Harper, Laurence A Brown, Robin Willows, Silvia Gandra, Victor Poncio, Márcio J de Oliveira Figueiredo, Nathan R Qi, Stuart N Peirson, Rory J McCrimmon, Balázs Gereben, László Tretter, Csaba Fekete, Charles Redwood, Giles SH Yeo, Lora K Heisler, Guy A Rutter, Mark A Smith, Dominic J Withers, David Carling, Eduardo B Sternick, Jonathan RS Arch, Michael A Cawthorne, Hugh Watkins, Houman Ashrafian
Sep 03, 2019
Despite significant advances in our understanding of the biology determining systemic energy homeostasis, the treatment of obesity remains a medical challenge. Activation of AMP-activated protein kinase (AMPK) has been proposed...
AMP-Activated Protein Kinases Adiposity Adult aging Agouti-Related Protein Animals Arcuate Nucleus of Hypothalamus Energy Metabolism Enzyme Activation Feeding Behavior Female Heterozygote Humans Hyperphagia Hypothalamus Insulin Insulin-Secreting Cells Male Mice Mitochondria Mutation Neurons obesity Oxidative Phosphorylation Receptors Ghrelin Ribosomes Signal Transduction Transcriptome Up-Regulation