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Voicing the professional doctorate and the researching professional's identity
Although there is increasing interest in how learning to become a researching professional is understood by students undertaking a professional doctorate of education (EdD), the topic remains under-researched and...
Functional connexin35 increased in the myopic chicken retina.
Seema Banerjee, Qing Wang, George Tang, Chunghim So, Sze Wan Shan, King Kit Li, Chi-Wai Do, Feng Pan
Jun 14, 2021
Our previous research showed that increased phosphorylation of connexin (Cx)36 indicated extended coupling of AII amacrine cells (ACs) in the rod-dominant mouse myopic retina. This research will determine whether...
The underlying structure of visuospatial working memory in children with mathematical learning disability.
This study examined visual, spatial-sequential, and spatial-simultaneous working memory (WM) performance in children with mathematical learning disability (MLD) and low mathematics achievement (LMA) compared with typically...
Targeting the latent human cytomegalovirus reservoir for T-cell-mediated killing with virus-specific nanobodies.
Timo WM De Groof, Elizabeth G Elder, Eleanor Y Lim, Raimond Heukers, Nick D Bergkamp, Ian J Groves, Mark Wills, John H Sinclair, Martine J Smit
Jul 23, 2021
Latent human cytomegalovirus (HCMV) infection is characterized by limited gene expression, making latent HCMV infections refractory to current treatments targeting viral replication. However, reactivation of latent HCMV in...
Automatic prioritization of self-referential stimuli in working memory
People preferentially attend to external stimuli that are related to themselves compared with others. Whether a similar self-reference bias applies to internal representations, such as those maintained in working memory (WM), is...
Interventions targeting working memory in 4-11 year olds within their everyday contexts
It has been suggested that diverse interventions applied within children's everyday contexts have the potential to improve working memory (WM) and produce transfer to real-world skills but little is known about the effectiveness...
Precise Topology of Adjacent Domain-General and Sensory-Biased Regions in the Human Brain.
Recent functional MRI studies identified sensory-biased regions across much of the association cortices and cerebellum. However, their anatomical relationship to multiple-demand (MD) regions, characterized as domain-general due...
A systematic review examining the characteristics of users of NHS patient medicines helpline services, and the types of enquiries they make
Background and objective: Patient medicines helpline services (PMHS) are available from some National Health Service Trusts in the United Kingdom to support patients following discharge. The aim of this systematic review was to...
Cerebral Microbleeds and Structural White Matter Integrity in Patients With Traumatic Brain Injury-A Diffusion Tensor Imaging Study.
Juho Dahl, Olli Tenovuo, Jussi P Posti, Jussi Hirvonen, Ari J Katila, Janek Frantzén, Henna-Riikka Maanpää, Riikka Takala, Eliisa Löyttyniemi, Jussi Tallus, Virginia Newcombe, David K Menon, Peter J Hutchinson, Mehrbod Mohammadian
Jul 18, 2022
Diffuse axonal injury (DAI) is a common neuropathological manifestation of traumatic brain injury (TBI), presenting as traumatic alterations in the cerebral white matter (WM) microstructure and often leading to long-term...
Automatic prioritization of self-referential stimuli in working memory
People preferentially attend to external stimuli that are related to themselves compared with others. Whether a similar self-reference bias applies to internal representations, such as those maintained in working memory (WM), is...
White and gray matter damage in primary progressive MS
Benedetta Bodini, Declan Chard, Daniel R Altmann, Daniel Tozer, David H Miller, Alan J Thompson, Claudia Wheeler-Kingshott, Olga Ciccarelli
Jun 22, 2018
OBJECTIVE: The temporal relationship between white matter (WM) and gray matter (GM) damage in vivo in early primary progressive multiple sclerosis (PPMS) was investigated testing 2 hypotheses: (1) WM tract abnormalities predict...
Sensitivity of Diffusion MRI to White Matter Pathology
Evgenios N Kornaropoulos, Stefan Winzeck, Theodor Rumetshofer, Anna Wikstrom, Linda Knutsson, Marta M Correia, Pia C Sundgren, Markus Nilsson
Jun 13, 2022
There are many ways to acquire and process diffusion MRI (dMRI) data for group studies, but it is unknown which maximizes the sensitivity to white matter (WM) pathology. Inspired by this question, we analyzed data acquired for...
Cerebral Microbleeds and Structural White Matter Integrity in Patients With Traumatic Brain Injury-A Diffusion Tensor Imaging Study.
Juho Dahl, Olli Tenovuo, Jussi P Posti, Jussi Hirvonen, Ari J Katila, Janek Frantzén, Henna-Riikka Maanpää, Riikka Takala, Eliisa Löyttyniemi, Jussi Tallus, Virginia Newcombe, David K Menon, Peter Hutchinson, Mehrbod Mohammadian
Jun 14, 2022
Diffuse axonal injury (DAI) is a common neuropathological manifestation of traumatic brain injury (TBI), presenting as traumatic alterations in the cerebral white matter (WM) microstructure and often leading to long-term...
Feature coding dataset for trained and untrained working memory tasks in randomized controlled trials of working memory training.
The data presented in this article are produced as part of the original research article entitled "Working memory training involves learning new skills" (Gathercole, Dunning, Holmes & Norris, in press). This article presents a...
Predictors of mathematics in primary school
We determined the relative importance of the so-called approximate number system (ANS), symbolic number comparison (SNC) and verbal and spatial short-term and working memory (WM) capacity for mathematics achievement in 1,254...
Oligodendrocyte-encoded Kir4.1 function is required for axonal integrity.
Lucas Schirmer, Wiebke Möbius, Chao Zhao, Andrés Cruz-Herranz, Lucile Ben Haim, Christian Cordano, Lawrence R Shiow, Kevin W Kelley, Boguslawa Sadowski, Garrett Timmons, Anne-Katrin Pröbstel, Jackie N Wright, Jung Hyung Sin, Michael Devereux, Daniel E Morrison, Sandra M Chang, Khalida Sabeur, Ari J Green, Klaus-Armin Nave, Robin Jm Franklin, David H Rowitch
Nov 19, 2018
Glial support is critical for normal axon function and can become dysregulated in white matter (WM) disease. In humans, loss-of-function mutations of KCNJ10, which encodes the inward-rectifying potassium channel KIR4.1, causes...
White Matter Microstructure in Youths with Conduct Disorder
Jack Rogers, Karen Gonzalez-Madruga, Gregor Kohls, Rosalind Baker, Roberta Clanton, Ruth Pauli, Philippa Birch, Alimul Chowdhury, Marietta Kirchner, Jesper Andersson, Areti Smaragdi, Ignazio Puzzo, Sarah Baumann, Nora Maria Raschle, Lynn Valérie Fehlbaum, Willeke Martine Menks, Martin Steppan, Christina Stadler, Kerstin Konrad, Christine Freitag, Graeme Fairchild, Stephane De Brito
Dec 01, 2019
Objective: Studies using diffusion tensor imaging (DTI) to investigate white matter (WM) microstructure in youths with conduct disorder (CD) have reported disparate findings. We investigated WM alterations in a large sample...
FEMNAT-CD Callous-unemotional traits Conduct Disorder diffusion tensor imaging (DTI) Sex differences /dk/atira/pure/subjectarea/asjc/3200/3204 name=Developmental and Educational Psychology /dk/atira/pure/subjectarea/asjc/2700/2738 name=Psychiatry and Mental health /dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_being name=SDG 3 - Good Health and Well-being
New perspectives on binding in visual working memory.
How does visual working memory (WM) store the binding between different features of a visual object (like colour, orientation, and location), and does memorizing these bindings require additional resources beyond memorizing...
Geographies of conservation I
WM ADAMS
Apr 22, 2016
© The Author(s) 2016. Extinction has long been a central concern in biodiversity conservation. Today, de-extinction offers interesting possibilities of restoring charismatic species and ecosystem function, but also risks and...
Sensitivity of Diffusion MRI to White Matter Pathology
Evgenios N Kornaropoulos, Stefan Winzeck, Theodor Rumetshofer, Anna Wikstrom, Linda Knutsson, Marta Morgado Correia, Pia C Sundgren, Markus Nilsson
May 10, 2022
There are many ways to acquire and process diffusion MRI (dMRI) data for group studies, but it is unknown which maximizes the sensitivity to white matter (WM) pathology. Inspired by this question, we analyzed data acquired for...
Diffusion MRI approaches for investigating microstructural complexity in a rat model of traumatic brain injury.
Karthik Chary, Eppu Manninen, Jade Claessens, Alonso Ramirez-Manzanares, Olli Gröhn, Alejandra Sierra
Feb 09, 2023
Our study explores the potential of conventional and advanced diffusion MRI techniques including diffusion tensor imaging (DTI), and single-shell 3-tissue constrained spherical deconvolution (SS3T-CSD) to investigate complex...
A systematic review examining the characteristics of users of NHS patient medicines helpline services, and the types of enquiries they make
Background and objective: Patient medicines helpline services (PMHS) are available from some National Health Service Trusts in the United Kingdom to support patients following discharge. The aim of this systematic review was to...
Reassessing the Evidence for Capacity Limits in Neural Signals Related to Working Memory.
Paul M Bays
Feb 28, 2018
In 2004, two landmark studies described the discovery of brain imaging (functional magnetic resonance imaging and electroencephalography) signals that increase with the number of items held in visual working memory (WM). These...
White-Matter Pathways for Statistical Learning of Temporal Structures.
Vasilis M Karlaftis, Rui Wang, Yuan Shen, Peter Tino, Guy Williams, Andrew E Welchman, Zoe Kourtzi
Aug 09, 2018
Extracting the statistics of event streams in natural environments is critical for interpreting current events and predicting future ones. The brain is known to rapidly find structure and meaning in unfamiliar streams of sensory...
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