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Detection of neutralising antibodies to SARS-CoV-2 to determine population exposure in Scottish blood donors between March and May 2020.
Craig P Thompson, Nicholas E Grayson, Robert S Paton, Jai S Bolton, José Lourenço, Bridget S Penman, Lian N Lee, Valerie Odon, Juthathip Mongkolsapaya, Senthil Chinnakannan, Wanwisa Dejnirattisai, Matthew Edmans, Alex Fyfe, Carol Imlach, Kreepa Kooblall, Nicholas Lim, Chang Liu, César López-Camacho, Carol McInally, Anna L McNaughton, Narayan Ramamurthy, Jeremy Ratcliff, Piyada Supasa, Oliver Sampson, Beibei Wang, Alexander J Mentzer, Marc Turner, Malcolm G Semple, Kenneth Baillie, ISARIC4C investigators, Heli Harvala, Gavin R Screaton, Nigel Temperton, Paul Klenerman, Lisa M Jarvis, Sunetra Gupta, Peter Simmonds
Jan 18, 2021
BackgroundThe progression and geographical distribution of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection in the United Kingdom (UK) and elsewhere is unknown because typically only symptomatic individuals...
Covid19 SARS-CoV-2 pandemic serology SURVEILLANCE Scotland Adult Antibodies Neutralizing Antibodies Viral Betacoronavirus Blood Donors covid-19 Cluster Analysis Coronavirus Infections Enzyme-Linked Immunosorbent Assay Female Geography Medical Humans Inhibitory Concentration 50 Male Models Immunological Neutralization Tests Pandemics Pneumonia Viral Population Surveillance prevalence SARS-CoV-2 Scotland Sensitivity and Specificity Seroepidemiologic Studies Urban Population
Evolution of long-term vaccine-induced and hybrid immunity in healthcare workers after different COVID-19 vaccine regimens.
Shona C Moore, Barbara Kronsteiner, Stephanie Longet, Sandra Adele, Alexandra S Deeks, Chang Liu, Wanwisa Dejnirattisai, Laura Silva Reyes, Naomi Meardon, Sian Faustini, Saly Al-Taei, Tom Tipton, Luisa M Hering, Adrienn Angyal, Rebecca Brown, Alexander R Nicols, Susan L Dobson, Piyada Supasa, Aekkachai Tuekprakhon, Andrew Cross, Jessica K Tyerman, Hailey Hornsby, Irina Grouneva, Megan Plowright, Peijun Zhang, Thomas AH Newman, Jeremy M Nell, Priyanka Abraham, Mohammad Ali, Tom Malone, Isabel Neale, Eloise Phillips, Joseph D Wilson, Sam M Murray, Martha Zewdie, Adrian Shields, Emily C Horner, Lucy H Booth, Lizzie Stafford, Sagida Bibi, Daniel G Wootton, Alexander J Mentzer, Christopher P Conlon, Katie Jeffery, Philippa C Matthews, Andrew J Pollard, Anthony Brown, Sarah L Rowland-Jones, Juthathip Mongkolsapaya, Rebecca P Payne, Christina Dold, Teresa Lambe, James ED Thaventhiran, Gavin Screaton, Eleanor Barnes, Susan Hopkins, Victoria Hall, Christopher JA Duncan, Alex Richter, Miles Carroll, Thushan I de Silva, Paul Klenerman, Susanna Dunachie, Lance Turtle, PITCH Consortium
Apr 02, 2023
BACKGROUND: Both infection and vaccination, alone or in combination, generate antibody and T cell responses against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). However, the maintenance of such responses-and...
Persistence of immunogenicity after seven COVID-19 vaccines given as third dose boosters following two doses of ChAdOx1 nCov-19 or BNT162b2 in the UK
Xinxue Liu, Alasdair PS Munro, Shuo Feng, Leila Janani, Parvinder K Aley, Gavin Babbage, David Baxter, Marcin Bula, Katrina Cathie, Krishna Chatterjee, Wanwisa Dejnirattisai, Kate Dodd, Yvanne Enever, Ehsaan Qureshi, Anna L Goodman, Christopher A Green, Linda Harndahl, John Haughney, Alexander Hicks, Agatha A van der Klaauw, Jonathan Kwok, Vincenzo Libri, Martin J Llewelyn, Alastair C McGregor, Angela M Minassian, Patrick Moore, Mehmood Mughal, Yama F Mujadidi, Kyra Holliday, Orod Osanlou, Rostam Osanlou, Daniel R Owens, Mihaela Pacurar, Adrian Palfreeman, Daniel Pan, Tommy Rampling, Karen Regan, Stephen Saich, Teona Serafimova, Dinesh Saralaya, Gavin R Screaton, Sunil Sharma, Ray Sheridan, Ann Sturdy, Piyada Supasa, Emma C Thomson, Shirley Todd, Chris Twelves, Robert C Read, Sue Charlton, Bassam Hallis, Mary Ramsay, Nick Andrews, Teresa Lambe, Jonathan S Nguyen-Van-Tam, Victoria Cornelius, Matthew D Snape, Saul N Faust, COV-BOOST study group
May 13, 2022
OBJECTIVES: To evaluate the persistence of immunogenicity three months after third dose boosters. METHODS: COV-BOOST is a multicentre, randomised, controlled, phase 2 trial of seven COVID-19 vaccines used as a third booster...
COVID-19 vaccine Fractional dose Heterologous boost Homologous boost Immunogenicity Persistence Third dose Ad26COVS1 Adult Aged Aged 80 and over Antibodies Viral BNT162 Vaccine covid-19 COVID-19 Vaccines ChAdOx1 nCoV-19 Humans Immunogenicity Vaccine Immunoglobulin G Middle Aged SARS-CoV-2 United Kingdom Viral Vaccines mRNA Vaccines
An immunodominant NP105-113-B*07
Yanchun Peng, Suet Ling Felce, Danning Dong, Frank Penkava, Alexander J Mentzer, Xuan Yao, Guihai Liu, Zixi Yin, Ji-Li Chen, Yongxu Lu, Dannielle Wellington, Peter AC Wing, Delaney CC Dominey-Foy, Chen Jin, Wenbo Wang, Megat Abd Hamid, Ricardo A Fernandes, Beibei Wang, Anastasia Fries, Xiaodong Zhuang, Neil Ashley, Timothy Rostron, Craig Waugh, Paul Sopp, Philip Hublitz, Ryan Beveridge, Tiong Kit Tan, Christina Dold, Andrew J Kwok, Charlotte Rich-Griffin, Wanwisa Dejnirattisa, Chang Liu, Prathiba Kurupati, Isar Nassiri, Robert A Watson, Orion Tong, Chelsea A Taylor, Piyush Kumar Sharma, Bo Sun, Fabiola Curion, Santiago Revale, Lucy C Garner, Kathrin Jansen, Ricardo C Ferreira, Moustafa Attar, Jeremy W Fry, Rebecca A Russell, COMBAT Consortium, Hans J Stauss, William James, Alain Townsend, Ling-Pei Ho, Paul Klenerman, Juthathip Mongkolsapaya, Gavin R Screaton, Calliope Dendrou, Stephen N Sansom, Rachael Bashford-Rogers, Benny Chain, Geoffrey L Smith, Jane A McKeating, Benjamin P Fairfax, Paul Bowness, Andrew J McMichael, Graham Ogg, Julian C Knight, Tao Dong
Jan 06, 2022
Aged Amino Acid Sequence Antibodies Viral Antibody Affinity covid-19 Cell Line Transformed Female Gene Expression Profiling HLA-B7 Antigen Humans Immunodominant Epitopes Immunologic Memory Male Middle Aged Nucleocapsid Proteins Receptors Antigen T-Cell SARS-CoV-2 Severity of Illness Index T-Lymphocytes Cytotoxic vaccinia virus