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Antibody mediated neutralization of myelin associated EphrinB3 accelerates CNS remyelination
The effect of a coding strategy that removes temporally masked pulses on speech perception by cochlear implant users.
Speech recognition in noisy environments remains a challenge for cochlear implant (CI) recipients. Unwanted charge interactions between current pulses, both within and between electrode channels, are likely to impair...
Cochlear implant Masking Speech Perception Temporal integrator Acoustic Stimulation Aged Aged 80 and over Cochlear Implantation cochlear implants Electric Stimulation Hearing Hearing Loss Humans Loudness Perception Male Middle Aged Noise Perceptual Masking Persons With Hearing Impairments Speech Intelligibility Speech Perception
Oligodendrocyte-encoded Kir4.1 function is required for axonal integrity.
Lucas Schirmer, Wiebke Möbius, Chao Zhao, Andrés Cruz-Herranz, Lucile Ben Haim, Christian Cordano, Lawrence R Shiow, Kevin W Kelley, Boguslawa Sadowski, Garrett Timmons, Anne-Katrin Pröbstel, Jackie N Wright, Jung Hyung Sin, Michael Devereux, Daniel E Morrison, Sandra M Chang, Khalida Sabeur, Ari J Green, Klaus-Armin Nave, Robin Jm Franklin, David H Rowitch
Nov 19, 2018
Glial support is critical for normal axon function and can become dysregulated in white matter (WM) disease. In humans, loss-of-function mutations of KCNJ10, which encodes the inward-rectifying potassium channel KIR4.1, causes...
Age differences in Machiavellianism across the life span
OBJECTIVE: Lifespan perspectives on personality development have gained much momentum in recent years, mostly focusing on benevolent and neutral traits such as the Big Five. Despite their strong associations with critical...
Evaluating Spatial Hearing Using a Dual-Task Approach in a Virtual-Acoustics Environment.
Marina Salorio-Corbetto, Ben Williges, Wiebke Lamping, Lorenzo Picinali, Deborah Vickers
Mar 28, 2022
Spatial hearing is critical for communication in everyday sound-rich environments. It is important to gain an understanding of how well users of bilateral hearing devices function in these conditions. The purpose of this work...
Evaluating Spatial Hearing Using a Dual-Task Approach in a Virtual-Acoustics Environment.
Marina Salorio-Corbetto, Ben Williges, Wiebke Lamping, Lorenzo Picinali, Deborah Vickers
Apr 29, 2022
Spatial hearing is critical for communication in everyday sound-rich environments. It is important to gain an understanding of how well users of bilateral hearing devices function in these conditions. The purpose of this work...
Cross-cultural variations in big five relationships with religiosity
Jochen E Gebauer, Wiebke Bleidorn, Samuel D Gosling, Peter J Rentfrow, Michael E Lamb, Jeff Potter
Mar 16, 2015
The Effect of Phantom Stimulation and Pseudomonophasic Pulse Shapes on Pitch Perception by Cochlear Implant Listeners.
It has been suggested that a specialized high-temporal-acuity brainstem pathway can be activated by stimulating more apically in the cochlea than is achieved by cochlear implants (CIs) when programmed with contemporary clinical...
Neuregulin 1 Type I Overexpression Is Associated with Reduced NMDA Receptor-Mediated Synaptic Signaling in Hippocampal Interneurons Expressing PV or CCK.
Dimitrios Kotzadimitriou, Wiebke Nissen, Melinda Paizs, Kathryn Newton, Paul J Harrison, Ole Paulsen, Karri Lamsa
May 16, 2018
Hypofunction of N-methyl-d-aspartate receptors (NMDARs) in inhibitory GABAergic interneurons is implicated in the pathophysiology of schizophrenia (SZ), a heritable disorder with many susceptibility genes. However, it is still...
Cultural norm fulfillment, interpersonal belonging, or getting ahead? A large-scale cross-cultural test of three perspectives on the function of self-esteem.
Jochen E Gebauer, Constantine Sedikides, Jenny Wagner, Wiebke Bleidorn, Peter J Rentfrow, Jeff Potter, Samuel D Gosling
Jun 16, 2015
Epidemiological impact and cost-effectiveness of universal vaccination with Bexsero(®) to reduce meningococcal group B disease in Germany.
Hannah Christensen, Tom Irving, Judith Koch, Caroline L Trotter, Bernhard Ultsch, Felix Weidemann, Ole Wichmann, Wiebke Hellenbrand
Apr 21, 2016
Evaluation of Possible Effects of a Potassium Channel Modulator on Temporal Processing by Cochlear Implant Listeners.
Robert P Carlyon, John M Deeks, François Guérit, Wiebke Lamping, Alexander J Billig, Charles H Large, Shakeel R Saeed, Peter Harris
Nov 19, 2018
AUT00063 Cochlear implant (CI) gap detection threshold (GDT) kv3.1 midpoint comparison procedure (MPC) rate discrimination ratio (RDR) Temporal processing Aged Aged 80 and over Auditory Perception cochlear implants Cross-Over Studies Deafness Double-Blind Method Hearing Tests Humans Imidazoles Middle Aged Pyrimidines Shaw Potassium Channels
Helical frontier orbitals of conjugated linear molecules
Compounds containing allenes, cumulenes and oligoynes (polyalkynes) have attracted attention for both their conformation and reactivity. Whilst the textbook molecular orbital description explains the general electronic and...
Helical frontier orbitals of conjugated linear molecules
Compounds containing allenes, cumulenes and oligoynes (polyalkynes) have attracted attention for both their conformation and reactivity. Whilst the textbook molecular orbital description explains the general electronic and...
The religiosity as social value hypothesis
Jochen E Gebauer, Constantine Sedikides, Felix D Schönbrodt, Wiebke Bleidorn, Peter J Rentfrow, Jeff Potter, Samuel D Gosling
Jun 07, 2018
Are religious people psychologically better or worse adjusted than their nonreligious counterparts? Hundreds of studies have reported a positive relation between religiosity and psychological adjustment. Recently, however, a...
Age and gender differences in self-esteem-A cross-cultural window.
Wiebke Bleidorn, Ruben C Arslan, Jaap JA Denissen, Peter J Rentfrow, Jochen E Gebauer, Jeff Potter, Samuel D Gosling
Jun 06, 2019
Research and theorizing on gender and age differences in self-esteem have played a prominent role in psychology over the past 20 years. However, virtually all empirical research has been undertaken in the United States or other...
An enhanced toolkit for the generation of knockout and marker-free fluorescent Plasmodium chabaudi.
Edward J Marr, Rachel M Milne, Burcu Anar, Gareth Girling, Frank Schwach, Jason P Mooney, Wiebke Nahrendorf, Philip J Spence, Deirdre Cunningham, David A Baker, Jean Langhorne, Julian C Rayner, Oliver Billker, Ellen S Bushell, Joanne Thompson
Jun 22, 2020
The rodent parasite Plasmodium chabaudi is an important in vivo model of malaria. The ability to produce chronic infections makes it particularly useful for investigating the development of anti- Plasmodium immunity, as well as...
Liouville quantum gravity and the Brownian map III
Abstract: Previous works in this series have shown that an instance of a 8/3-Liouville quantum gravity (LQG) sphere has a well-defined distance function, and that the resulting metric measure space (mm-space) agrees in law with...
Thyroid Hormone Receptor Beta in the Ventromedial Hypothalamus Is Essential for the Physiological Regulation of Food Intake and Body Weight.
Saira Hameed, Michael Patterson, Waljit S Dhillo, Sofia A Rahman, Yue Ma, Christopher Holton, Apostolos Gogakos, Giles SH Yeo, Brian YH Lam, Joseph Polex-Wolf, Wiebke Fenske, Jimmy Bell, Jelena Anastasovska, Jacques Samarut, Stephen R Bloom, JH Duncan Bassett, Graham R Williams, James V Gardiner
Aug 18, 2017
The obesity epidemic is a significant global health issue. Improved understanding of the mechanisms that regulate appetite and body weight will provide the rationale for the design of anti-obesity therapies. Thyroid hormones...
Mapping the proteo-genomic convergence of human diseases.
Maik Pietzner, Eleanor Wheeler, Julia Carrasco-Zanini, Adrian Cortes, Mine Koprulu, Maria A Wörheide, Erin Oerton, James Cook, Isobel D Stewart, Nicola D Kerrison, Jian'an Luan, Johannes Raffler, Matthias Arnold, Wiebke Arlt, Stephen O'Rahilly, Gabi Kastenmüller, Eric R Gamazon, Aroon D Hingorani, Robert A Scott, Nicholas J Wareham, Claudia Langenberg
Oct 07, 2021
aging Alternative Splicing Blood Proteins covid-19 Connective Tissue Diseases Disease Drug development Female Gallstones Genetic Association Studies genetic variation Genome Human Genome-Wide Association Study Genomics Humans Internet Male Phenotype Proteins Proteome Quantitative Trait Loci Sex Characteristics
The Early Effects of Rapid Androgen Deprivation on Human Prostate Cancer.
Greg L Shaw, Hayley Whitaker, Marie Corcoran, Mark J Dunning, Hayley Luxton, Jonathan Kay, Charlie E Massie, Jodi L Miller, Alastair D Lamb, Helen Ross-Adams, Roslin Russell, Adam W Nelson, Matthew D Eldridge, Andrew G Lynch, Antonio Ramos-Montoya, Ian G Mills, Angela E Taylor, Wiebke Arlt, Nimish Shah, Anne Y Warren, David E Neal
Nov 04, 2015
Androgen receptor Castration clinical trial Gene transcription Immunohistochemistry prostate cancer Estrogen Receptor alpha Gene Expression Profiling Gene Expression Regulation Neoplastic Hormone Antagonists Humans Immunohistochemistry Male Oligopeptides Preoperative Care Prostate Prostatectomy Prostatic Neoplasms Receptors Androgen Spectrum Analysis
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