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Synthetic long peptide booster immunization in rhesus macaques primed with replication-competent NYVAC-C-KC induces a balanced CD4/CD8 T-cell and antibody response against the conserved regions of HIV-1.
Petra Mooij, Gerrit Koopman, Jan Wouter Drijfhout, Ivonne G Nieuwenhuis, Niels Beenhakker, Josef Koestler, Willy MJM Bogers, Ralf Wagner, Mariano Esteban, Giuseppe Pantaleo, Jonathan L Heeney, Bertram L Jacobs, Cornelis JM Melief
Jun 11, 2015
Increased, Durable B-Cell and ADCC Responses Associated with T-Helper Cell Responses to HIV-1 Envelope in Macaques Vaccinated with gp140 Occluded at the CD4 Receptor Binding Site.
Willy MJM Bogers, Susan W Barnett, Herman Oostermeijer, Ivonne G Nieuwenhuis, Niels Beenhakker, Daniella Mortier, Petra Mooij, Gerrit Koopman, Edmund Remarque, Gregoire Martin, Rachel Pei-Jen Lai, Antu K Dey, Yide Sun, Brian Burke, Guido Ferrari, David Montefiori, Loic Martin, David Davis, Indresh Srivastava, Jonathan L Heeney
Aug 17, 2017
B-cell responses CD4 mimetic CD4 occluded T-cell responses human immunodeficiency virus nonhuman primates vaccines AIDS Vaccines Animals Antibodies Neutralizing Antibody-Dependent Cell Cytotoxicity B-Lymphocytes Binding Sites Antibody CD4 Antigens HIV Antibodies HIV-1 Macaca mulatta T-Lymphocytes Helper-Inducer Vaccination env Gene Products Human Immunodeficiency Virus
Large ferro–pyro–phototronic effect in 0.5Ba(Zr<inf>0.2</inf>Ti<inf>0.8</inf>)O<inf>3</inf>–0.5(Ba<inf>0.7</inf>Ca<inf>0.3</inf>)TiO<inf>3</inf> thin films integrated on silicon for photodetection
Coupling together the ferroelectric, pyroelectric, and photovoltaic characteristics within a single material is a novel way to improve the performance of photodetectors. In this work, we take advantage of the triple...
Dendrochronological evidence for long-distance timber trading in the Roman Empire.
An important question for our understanding of Roman history is how the Empire's economy was structured, and how long-distance trading within and between its provinces was organised and achieved. Moreover, it is still unclear...
A systematic review of school-based interventions targeting physical activity and sedentary behaviour among older adolescents.
S-T Hynynen, MM van Stralen, FF Sniehotta, V Araújo-Soares, W Hardeman, MJM Chinapaw, T Vasankari, N Hankonen
Aug 18, 2015
Radiocarbon offsets and old world chronology as relevant to Mesopotamia, Egypt, Anatolia and Thera (Santorini)
Sturt W. Manning, Lukas Wacker, Ulf Büntgen, Christopher Bronk Ramsey, Michael W. Dee, Bernd Kromer, Brita Lorentzen, Willy Tegel
Aug 17, 2021
Abstract: The new IntCal20 radiocarbon record continues decades of successful practice by employing one calibration curve as an approximation for different regions across the hemisphere. Here we investigate three radiocarbon...
Predicted climate change will increase the truffle cultivation potential in central Europe.
Tomáš Čejka, Miroslav Trnka, Paul J Krusic, Ulrich Stobbe, Daniel Oliach, Tomáš Václavík, Willy Tegel, Ulf Büntgen
Jan 11, 2021
Climate change affects the distribution of many species, including Burgundy and Périgord truffles in central and southern Europe, respectively. The cultivation potential of these high-prized cash crops under future warming...
Tree rings reveal signs of Europe's sustainable forest management long before the first historical evidence.
Bernhard Muigg, Georgios Skiadaresis, Willy Tegel, Franz Herzig, Paul J Krusic, Uwe E Schmidt, Ulf Büntgen
Feb 22, 2021
To satisfy the increasing demand for wood in central Europe during medieval times, a new system of forest management was developed, one far superior to simple coppicing. The adoption of a sophisticated, Coppice-with-Standards...
Predicted climate change will increase the truffle cultivation potential in central Europe
Tomáš Čejka, Miroslav Trnka, Paul J. Krusic, Ulrich Stobbe, Daniel Oliach, Tomáš Václavík, Willy Tegel, Ulf Büntgen
Dec 04, 2020
Abstract: Climate change affects the distribution of many species, including Burgundy and Périgord truffles in central and southern Europe, respectively. The cultivation potential of these high-prized cash crops under future...
Radiocarbon offsets and old world chronology as relevant to Mesopotamia, Egypt, Anatolia and Thera (Santorini)
Sturt W. Manning, Lukas Wacker, Ulf Büntgen, Christopher Bronk Ramsey, Michael W. Dee, Bernd Kromer, Brita Lorentzen, Willy Tegel
Aug 17, 2020
Abstract: The new IntCal20 radiocarbon record continues decades of successful practice by employing one calibration curve as an approximation for different regions across the hemisphere. Here we investigate three radiocarbon...
Radiocarbon offsets and old world chronology as relevant to Mesopotamia, Egypt, Anatolia and Thera (Santorini).
Sturt W Manning, Lukas Wacker, Ulf Büntgen, Christopher Bronk Ramsey, Michael W Dee, Bernd Kromer, Brita Lorentzen, Willy Tegel
Oct 05, 2020
The new IntCal20 radiocarbon record continues decades of successful practice by employing one calibration curve as an approximation for different regions across the hemisphere. Here we investigate three radiocarbon time-series...
Hidden fairy rings and males-Genetic patterns of natural Burgundy truffle (Tuber aestivum Vittad.) populations reveal new insights into its life cycle.
Systematic lymphadenectomy versus sampling of ipsilateral mediastinal lymph-nodes during lobectomy for non-small-cell lung cancer
Sahar Mokhles, Fergus Macbeth, Tom Treasure, Riad N Younes, Robert C Rintoul, Francesca Fiorentino, Ad JJC Bogers, Johanna JM Takkenberg
Sep 08, 2018
OBJECTIVES: To re-examine the evidence for recommendations for complete dissection versus sampling of ipsilateral mediastinal lymph nodes during lobectomy for cancer. METHODS: We searched for randomized trials of systematic...
The fall of the summer truffle
Brian S Steidinger, Ulf Büntgen, Uli Stobbe, Willy Tegel, Ludger Sproll, Matthias Haeni, Barbara Moser, István Bagi, José-Antonio Bonet, Marc Buée, Benjamin Dauphin, Fernando Martínez-Peña, Virginie Molinier, Roman Zweifel, Simon Egli, Martina Peter
Oct 06, 2022
Global warming is pushing populations outside their range of physiological tolerance. According to the environmental envelope framework, the most vulnerable populations occur near the climatic edge of their species'...
Ursinus College Bulletin, Spring 1991
Stephen Heacock, Richard P. Richter, Sally Widman, John Updike, Jon Volkmer, Charlie Jamison, Dave Sherman
Jan 01, 0001
President's memo Letters Bomberger Hall at 100 President Bush's wartime reading? Student receives research grant Ursinus and ISOM 9 Standeven wins McClung Award Kresge grant Hobnobbing with Hollywood's honchos Ursinus...
Ursinus College Collegeville Pennsylvania alumni Deaths Marriages Annual Fund residence halls Sigma Rho Lambda Bomberger Memorial Hall Bonnie Hutchison Andrew Standeven ISOM conference Alan McCabe Ronald E. Hess Hugh R. Clark James L. Baer Michael J. Lewis Berman Art Museum Linda Grace Hoyer John Updike Nigeria Liberia Trina Derstine Jennifer Derstine Basketball Athletic Hall of Fame Caryn Maxim Ruth Kurisu C. Eugene Blum William T. Parsons Higher Education Social History United States History
Published by: Ursinus College
Macaques primed with self-amplifying RNA vaccines expressing HIV-1 envelope and boosted with recombinant protein show potent T- and B-cell responses
WM Bogers, H Oostermeijer, P Mooij, G Koopman, E Verschoor, D Davis, JL Heeney, Y Cu, K Banerjee, B Burke, A Dey, A Geall, SW Barnett
Sep 13, 2012
RIGHTS : This article is licensed under the BioMed Central licence at http://www.biomedcentral.com/about/license which is similar to the 'Creative Commons Attribution Licence'. In brief you may : copy, distribute, and display...
Crosslinking of a CD4 Mimetic Miniprotein with HIV-1 Env gp140 Alters Kinetics and Specificities of Antibody Responses against HIV-1 Env in Macaques
X Shen, WM Bogers, NL Yates, G Ferrari, AK Dey, WT Williams, FH Jaeger, K Wiehe, S Sawant, SM Alam, CC LaBranche, DC Montefiori, L Martin, I Srivastava, J Heeney, SW Barnett, GD Tomaras
Aug 03, 2017
CD4 mimetic Antibody epitope exposure human immunodeficiency virus nonhuman primate structural modification vaccine AIDS Vaccines Animals Antibodies Neutralizing Antibody-Dependent Cell Cytotoxicity CD4 Antigens CD4-Positive T-Lymphocytes Epitopes HIV Antibodies HIV Envelope Protein gp120 HIV-1 Immunoglobulin A Immunoglobulin G Macaca mulatta Vaccination env Gene Products Human Immunodeficiency Virus
Atmospheric characterization of terrestrial exoplanets in the mid-infrared
Sascha P Quanz, Olivier Absil, Willy Benz, Xavier Bonfils, Jean-Philippe Berger, Denis Defrère, Ewine van Dishoeck, David Ehrenreich, Jonathan Fortney, Adrian Glauser, John Lee Grenfell, Markus Janson, Stefan Kraus, Oliver Krause, Lucas Labadie, Sylvestre Lacour, Michael Line, Hendrik Linz, Jérôme Loicq, Yamila Miguel, Enric Pallé, Didier Queloz, Heike Rauer, Ignasi Ribas, Sarah Rugheimer, Franck Selsis, Ignas Snellen, Alessandro Sozzetti, Karl R Stapelfeldt, Stephane Udry, Mark Wyatt
Apr 13, 2023
Exoplanet science is one of the most thriving fields of modern astrophysics. A major goal is the atmospheric characterization of dozens of small, terrestrial exoplanets in order to search for signatures in their atmospheres that...
mid-infrared Extrasolar planets Habitability Planetary atmospheres Direct imaging Space interferometry
Published by: Experimental astronomy
Atmospheric characterization of terrestrial exoplanets in the mid-infrared
Sascha P Quanz, Olivier Absil, Willy Benz, Xavier Bonfils, Jean-Philippe Berger, Denis Defrère, Ewine van Dishoeck, David Ehrenreich, Jonathan Fortney, Adrian Glauser, John Lee Grenfell, Markus Janson, Stefan Kraus, Oliver Krause, Lucas Labadie, Sylvestre Lacour, Michael Line, Hendrik Linz, Jérôme Loicq, Yamila Miguel, Enric Pallé, Didier Queloz, Heike Rauer, Ignasi Ribas, Sarah Rugheimer, Franck Selsis, Ignas Snellen, Alessandro Sozzetti, Karl R Stapelfeldt, Stephane Udry, Mark Wyatt
Mar 09, 2023
Astrocyte-targeted gene delivery of interleukin 2 specifically increases brain-resident regulatory T cell numbers and protects against pathological neuroinflammation.
Lidia Yshii, Emanuela Pasciuto, Pascal Bielefeld, Loriana Mascali, Pierre Lemaitre, Marika Marino, James Dooley, Lubna Kouser, Stijn Verschoren, Vasiliki Lagou, Hannelore Kemps, Pascal Gervois, Antina de Boer, Oliver T Burton, Jérôme Wahis, Jens Verhaert, Samar Hk Tareen, Carlos P Roca, Kailash Singh, Carly E Whyte, Axelle Kerstens, Zsuzsanna Callaerts-Vegh, Suresh Poovathingal, Teresa Prezzemolo, Keimpe Wierda, Amy Dashwood, Junhua Xie, Elien Van Wonterghem, Eline Creemers, Meryem Aloulou, Willy Gsell, Oihane Abiega, Sebastian Munck, Roosmarijn E Vandenbroucke, Annelies Bronckaers, Robin Lemmens, Bart De Strooper, Ludo Van Den Bosch, Uwe Himmelreich, Carlos P Fitzsimons, Matthew G Holt, Adrian Liston
Jun 08, 2022
The ability of immune-modulating biologics to prevent and reverse pathology has transformed recent clinical practice. Full utility in the neuroinflammation space, however, requires identification of both effective targets for...
Astrocyte-targeted gene delivery of interleukin 2 specifically increases brain-resident regulatory T cell numbers and protects against pathological neuroinflammation.
Lidia Yshii, Emanuela Pasciuto, Pascal Bielefeld, Loriana Mascali, Pierre Lemaitre, Marika Marino, James Dooley, Lubna Kouser, Stijn Verschoren, Vasiliki Lagou, Hannelore Kemps, Pascal Gervois, Antina de Boer, Oliver T Burton, Jérôme Wahis, Jens Verhaert, Samar Hk Tareen, Carlos P Roca, Kailash Singh, Carly E Whyte, Axelle Kerstens, Zsuzsanna Callaerts-Vegh, Suresh Poovathingal, Teresa Prezzemolo, Keimpe Wierda, Amy Dashwood, Junhua Xie, Elien Van Wonterghem, Eline Creemers, Meryem Aloulou, Willy Gsell, Oihane Abiega, Sebastian Munck, Roosmarijn E Vandenbroucke, Annelies Bronckaers, Robin Lemmens, Bart De Strooper, Ludo Van Den Bosch, Uwe Himmelreich, Carlos P Fitzsimons, Matthew G Holt, Adrian Liston
Jun 29, 2022
The ability of immune-modulating biologics to prevent and reverse pathology has transformed recent clinical practice. Full utility in the neuroinflammation space, however, requires identification of both effective targets for...
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