Dynamic 13C Flux Analysis Captures the Reorganization of Adipocyte Glucose Metabolism in Response to Insulin.
Lake-Ee Quek,
James R Krycer,
Satoshi Ohno,
Katsuyuki Yugi,
Daniel J Fazakerley,
Richard Scalzo,
Sarah D Elkington,
Ziwei Dai,
Akiyoshi Hirayama,
Satsuki Ikeda,
Futaba Shoji,
Kumi Suzuki,
Jason W Locasale,
Tomoyoshi Soga,
David E James,
Shinya Kuroda
Apr 06, 2020
Cellular metabolism is dynamic, but quantifying non-steady metabolic fluxes by stable isotope tracers presents unique computational challenges. Here, we developed an efficient 13C-tracer dynamic metabolic flux analysis...